{"id":"https://openalex.org/W2211887481","doi":null,"title":"Effect of simulated adult and infant digestion on the antioxidant and cellular protective effects of Camellia sinensis and Aspalathus linearis tea","display_name":"Effect of simulated adult and infant digestion on the antioxidant and cellular protective effects of Camellia sinensis and Aspalathus linearis tea","publication_year":2015,"publication_date":"2015-09-01","ids":{"openalex":"https://openalex.org/W2211887481","mag":"2211887481"},"language":"en","primary_location":{"id":"pmh:oai:repository.up.ac.za:2263/50724","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2263/50724","pdf_url":"http://hdl.handle.net/2263/50724","source":{"id":"https://openalex.org/S4306401870","display_name":"UpSpace Institutional Repository (University of Pretoria)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I69552723","host_organization_name":"University of Pretoria","host_organization_lineage":["https://openalex.org/I69552723"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dissertation"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/2263/50724","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"P.J. Muller","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"P.J. Muller","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11411","display_name":"Tea Polyphenols and Effects","score":0.6215999722480774,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11411","display_name":"Tea Polyphenols and Effects","score":0.6215999722480774,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.37720000743865967,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11264","display_name":"Coffee research and impacts","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/camellia-sinensis","display_name":"Camellia sinensis","score":0.8970000147819519},{"id":"https://openalex.org/keywords/aspalathus-linearis","display_name":"Aspalathus linearis","score":0.984000027179718},{"id":"https://openalex.org/keywords/fermented-tea","display_name":"fermented tea","score":0.7770000100135803},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.7419999837875366},{"id":"https://openalex.org/keywords/in-vitro-digestion","display_name":"in vitro digestion","score":0.7860000133514404},{"id":"https://openalex.org/keywords/infant-digestion","display_name":"infant digestion","score":0.9810000061988831},{"id":"https://openalex.org/keywords/polyphenols","display_name":"polyphenols","score":0.800000011920929},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.968999981880188},{"id":"https://openalex.org/keywords/nitric-oxide-scavenging","display_name":"nitric oxide scavenging","score":0.824999988079071},{"id":"https://openalex.org/keywords/caco-2-cells","display_name":"Caco-2 cells","score":0.8370000123977661},{"id":"https://openalex.org/keywords/cytoprotection","display_name":"cytoprotection","score":0.49399998784065247},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.8610000014305115},{"id":"https://openalex.org/keywords/bioaccessibility","display_name":"bioaccessibility","score":0.4620000123977661}],"concepts":[{"id":"https://openalex.org/C2992816389","wikidata":"https://www.wikidata.org/wiki/Q101815","display_name":"Camellia sinensis","level":2,"score":0.9480578899383545},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.6053010821342468},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.5209333300590515},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4475767910480499},{"id":"https://openalex.org/C2781357212","wikidata":"https://www.wikidata.org/wiki/Q5275608","display_name":"Digestion (alchemy)","level":2,"score":0.4265546202659607},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.3392183482646942},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.29074010252952576},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2771236300468445},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23031669855117798},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.14194869995117188},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:repository.up.ac.za:2263/50724","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2263/50724","pdf_url":"http://hdl.handle.net/2263/50724","source":{"id":"https://openalex.org/S4306401870","display_name":"UpSpace Institutional Repository (University of Pretoria)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I69552723","host_organization_name":"University of Pretoria","host_organization_lineage":["https://openalex.org/I69552723"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dissertation"},{"id":"mag:2211887481","doi":null,"is_oa":false,"landing_page_url":"https://repository.up.ac.za/handle/2263/50724","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:repository.up.ac.za:2263/50724","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2263/50724","pdf_url":"http://hdl.handle.net/2263/50724","source":{"id":"https://openalex.org/S4306401870","display_name":"UpSpace Institutional Repository (University of Pretoria)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I69552723","host_organization_name":"University of Pretoria","host_organization_lineage":["https://openalex.org/I69552723"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dissertation"},"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"},{"score":0.4359000027179718,"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320692","display_name":"University of Pretoria","ror":"https://ror.org/00g0p6g84"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2211887481.pdf","grobid_xml":"https://content.openalex.org/works/W2211887481.grobid-xml"},"referenced_works_count":115,"referenced_works":["https://openalex.org/W641770611","https://openalex.org/W1482309452","https://openalex.org/W1877059317","https://openalex.org/W1914843938","https://openalex.org/W1937169612","https://openalex.org/W1963503466","https://openalex.org/W1966881539","https://openalex.org/W1969318170","https://openalex.org/W1970536865","https://openalex.org/W1972009654","https://openalex.org/W1972508135","https://openalex.org/W1972715563","https://openalex.org/W1974079203","https://openalex.org/W1974789390","https://openalex.org/W1975895609","https://openalex.org/W1978042751","https://openalex.org/W1979189704","https://openalex.org/W1981157132","https://openalex.org/W1981577290","https://openalex.org/W1981637398","https://openalex.org/W1982009066","https://openalex.org/W1983207054","https://openalex.org/W1985236418","https://openalex.org/W1988696784","https://openalex.org/W1988925065","https://openalex.org/W1992538565","https://openalex.org/W1993034915","https://openalex.org/W1993695095","https://openalex.org/W1996638916","https://openalex.org/W2000519650","https://openalex.org/W2000732112","https://openalex.org/W2001106467","https://openalex.org/W2001834891","https://openalex.org/W2005076338","https://openalex.org/W2007183030","https://openalex.org/W2007790334","https://openalex.org/W2007837111","https://openalex.org/W2010816660","https://openalex.org/W2011514657","https://openalex.org/W2014114876","https://openalex.org/W2020018314","https://openalex.org/W2021174872","https://openalex.org/W2021438241","https://openalex.org/W2025727132","https://openalex.org/W2025941585","https://openalex.org/W2027680092","https://openalex.org/W2027823058","https://openalex.org/W2027921068","https://openalex.org/W2028821224","https://openalex.org/W2029097306","https://openalex.org/W2029327224","https://openalex.org/W2031529504","https://openalex.org/W2037256135","https://openalex.org/W2038644618","https://openalex.org/W2046215898","https://openalex.org/W2046908156","https://openalex.org/W2048343883","https://openalex.org/W2050208507","https://openalex.org/W2050822595","https://openalex.org/W2050897897","https://openalex.org/W2053625942","https://openalex.org/W2054230997","https://openalex.org/W2054418710","https://openalex.org/W2054882765","https://openalex.org/W2056580915","https://openalex.org/W2057687949","https://openalex.org/W2058247783","https://openalex.org/W2061929176","https://openalex.org/W2064099549","https://openalex.org/W2065503241","https://openalex.org/W2065678834","https://openalex.org/W2067838245","https://openalex.org/W2070785261","https://openalex.org/W2072497577","https://openalex.org/W2077531758","https://openalex.org/W2080058698","https://openalex.org/W2080636610","https://openalex.org/W2082178298","https://openalex.org/W2084375116","https://openalex.org/W2086868978","https://openalex.org/W2087692771","https://openalex.org/W2090901001","https://openalex.org/W2091348010","https://openalex.org/W2091382514","https://openalex.org/W2092308614","https://openalex.org/W2095786197","https://openalex.org/W2097826825","https://openalex.org/W2107157101","https://openalex.org/W2111222642","https://openalex.org/W2113140652","https://openalex.org/W2118837440","https://openalex.org/W2120982778","https://openalex.org/W2127157107","https://openalex.org/W2127718764","https://openalex.org/W2129097213","https://openalex.org/W2130171550","https://openalex.org/W2132407933","https://openalex.org/W2132985922","https://openalex.org/W2138823361","https://openalex.org/W2140573009","https://openalex.org/W2144868623","https://openalex.org/W2145292804","https://openalex.org/W2149421704","https://openalex.org/W2149476637","https://openalex.org/W2151905670","https://openalex.org/W2153473625","https://openalex.org/W2155382398","https://openalex.org/W2162518284","https://openalex.org/W2163744431","https://openalex.org/W2167631033","https://openalex.org/W2168556140","https://openalex.org/W2183852738","https://openalex.org/W2185342906","https://openalex.org/W2334959688","https://openalex.org/W2437360500"],"related_works":["https://openalex.org/W3204111029","https://openalex.org/W3181705430","https://openalex.org/W3194973178","https://openalex.org/W2331230758","https://openalex.org/W4239679910","https://openalex.org/W3200686023","https://openalex.org/W4412630102","https://openalex.org/W4294683787","https://openalex.org/W3021697179","https://openalex.org/W3158285963"],"abstract_inverted_index":{"Background:":[0],"Many":[1],"South":[2],"Africans":[3],"have":[4,378],"a":[5,28,246,350,385],"poor":[6],"antioxidant":[7,61,144,164,217,380,389],"status":[8],"and":[9,14,25,41,70,82,89,94,105,115,129,160,169,193,204,224,229,236,254,271,280,290,296,305,313,365,396,403,407,423],"fermented":[10,369],"Camellia":[11],"sinensis":[12],"(BT)":[13],"Aspalathus":[15],"linearis":[16],"(RT)":[17],"teas":[18,65,331],"that":[19,309,353],"are":[20,66],"widely":[21],"consumed":[22],"by":[23,38,68,221,259,263],"adults":[24],"infants":[26],"is":[27],"possible":[29],"source":[30],"of":[31,51,63,77,136,172,186,191,197,227,269,301,320,329,337,368,388,405],"antioxidants":[32],"which":[33,60,414],"can":[34],"address":[35],"this":[36,52],"deficiency":[37],"protecting":[39],"cells":[40],"tissue":[42],"against":[43,275,356],"reactive":[44],"oxygen":[45],"species":[46],"damage.":[47],"\\nObjective:":[48],"The":[49,132,299],"aim":[50],"study":[53],"was":[54,119,123,155,278,288,303,307,375],"to":[55,59,92,180,377],"determine":[56],"the":[57,111,126,142,147,152,167,189,222,318,335,401,417],"extent":[58],"properties":[62,165,381],"these":[64,163],"affected":[67,258],"adult":[69,93,159,205,235,264,284],"infant":[71,95,161,203,211,237,260,267,366],"gastrointestinal":[72],"digestion.":[73,99,250,265],"\\nMethods:":[74],"Water":[75],"extracts":[76],"BT":[78,198,228,270,295,312,370,397,411],"(n":[79,84],"=":[80,85],"4)":[81],"RT":[83,230,316,395],"3)":[86],"were":[87,90,174,231,256],"prepared":[88],"subjected":[91],"simulated":[96],"in":[97,146,166,216,372,400],"vitro":[98],"For":[100,283],"pH":[101,181,357],"controls,":[102],"stomach":[103],"(SD)":[104],"subsequent":[106],"duodenal":[107],"digestion":[108,162,173,261,268],"(SDD)":[109],"fractions":[110],"total":[112],"polyphenolic":[113],"(TPC)":[114],"flavonoid":[116],"(TFC)":[117],"content":[118],"determined.":[120],"Antioxidant":[121],"activity":[122,145,218,390],"determined":[124,220],"with":[125,202,210,371],"DPPH,":[127],"TEAC":[128,240],"ORAC":[130,225],"assays.":[131],"NO":[133,251],"scavenging":[134,252],"ability":[135],"each":[137],"fraction":[138],"as":[139,141,207,209,219,349],"well":[140,208],"cellular":[143,273,286],"Caco-2":[148],"cell":[149],"line":[150],"using":[151],"DCHF-DA":[153],"assay":[154,241,253],"evaluated.":[156],"\\nResults:":[157],"With":[158],"SD":[168],"SDD":[170],"phase":[171],"increased,":[175],"unchanged":[176],"or":[177,184,360],"reduced":[178],"due":[179],"dependent":[182],"extraction":[183],"degradation":[185,359],"polyphenolics":[187],"and/or":[188],"biotransformation":[190],"flavanols":[192],"other":[194],"flavonoids.":[195],"TFC":[196],"remained":[199,391],"relatively":[200],"stable":[201],"digestion,":[206,238,285,393],"digested":[212,294],"RT.":[213,383],"Significant":[214],"losses":[215],"DPPH":[223],"assays":[226],"found":[232,308,376],"following":[233,249,392],"complete":[234,293],"whereas":[239],"did":[242],"not":[243],"show":[244],"such":[245],"great":[247],"loss":[248],"DCFH-DA":[255],"less":[257],"than":[262,334,382],"Following":[266],"RT,":[272,297,416],"protection":[274,287],"oxidative":[276],"damage":[277],"94.97%":[279],"83.99%,":[281],"respectively.":[282,298],"83.15%":[289],"71.71%":[291],"for":[292,325,343,420],"RSC":[300],"tea":[302],"calculated":[304],"it":[306],"one":[310],"cup":[311,328],"two":[314],"cups":[315],"provided":[317,332],"equivalent":[319,336],"200":[321],"mg":[322,339],"vitamin":[323,340],"C":[324,341],"adults.":[326,426],"One":[327],"both":[330,394],"more":[333],"30":[338],"needed":[342],"infants.":[344],"GIT":[345],"enzymes":[346],"may":[347,398],"serve":[348],"protein":[351],"matrix":[352],"protects":[354],"polyphenols":[355],"driven":[358],"quench":[361],"radicals.":[362],"\\nConclusion:":[363],"Adult":[364],"digests":[367],"most":[373],"instances":[374],"better":[379,418],"As":[384],"significant":[386],"amount":[387],"assist":[399],"prevention":[402],"management":[404],"infections":[406],"chronic":[408],"diseases.":[409],"However":[410],"contains":[412],"caffeine":[413,424],"makes":[415],"choice":[419],"infants,":[421],"children":[422],"sensitive":[425]},"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}