{"id":"https://openalex.org/W2211032348","doi":"https://doi.org/10.1016/s0076-6879(77)46060-9","title":"[56] Bivalent affinity labeling haptens in the formation of model immune complexes","display_name":"[56] Bivalent affinity labeling haptens in the formation of model immune complexes","publication_year":1977,"publication_date":"1977-01-01","ids":{"openalex":"https://openalex.org/W2211032348","doi":"https://doi.org/10.1016/s0076-6879(77)46060-9","mag":"2211032348","pmid":"https://pubmed.ncbi.nlm.nih.gov/561876"},"language":"en","primary_location":{"id":"doi:10.1016/s0076-6879(77)46060-9","doi":"https://doi.org/10.1016/s0076-6879(77)46060-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0076-6879(77)46060-9","pdf_url":null,"source":{"id":"https://openalex.org/S182211142","display_name":"Methods in enzymology on CD-ROM/Methods in enzymology","issn_l":"0076-6879","issn":["0076-6879","1079-2376","1557-7988"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319955","host_organization_name":"Academic Press","host_organization_lineage":["https://openalex.org/P4310319955","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Academic Press","Elsevier BV"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in Enzymology","raw_type":"book-chapter"},"volume":null,"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056507445","display_name":"Paul H. Pl\u00f6tz","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Paul H Plotz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5056507445"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.6495,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.92634561,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":"46","issue":null,"first_page":"505","last_page":"508"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.7827000021934509,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.7827000021934509,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.1843000054359436,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/immune-complexes","display_name":"immune complexes","score":0.9200000166893005},{"id":"https://openalex.org/keywords/covalent-cross-linking","display_name":"covalent cross-linking","score":0.6959999799728394},{"id":"https://openalex.org/keywords/hapten-synthesis","display_name":"hapten synthesis","score":0.7419999837875366},{"id":"https://openalex.org/keywords/polymerization","display_name":"polymerization","score":0.4189999997615814},{"id":"https://openalex.org/keywords/affinity-chromatography","display_name":"affinity chromatography","score":0.6359999775886536},{"id":"https://openalex.org/keywords/p-nitrophenol-release","display_name":"p-nitrophenol release","score":0.8880000114440918},{"id":"https://openalex.org/keywords/complement-system","display_name":"complement system","score":0.5339999794960022},{"id":"https://openalex.org/keywords/immunoglobulin-receptors","display_name":"immunoglobulin receptors","score":0.8560000061988831}],"concepts":[{"id":"https://openalex.org/C2776620830","wikidata":"https://www.wikidata.org/wiki/Q4919211","display_name":"Bivalent (engine)","level":3,"score":0.9341314435005188},{"id":"https://openalex.org/C29144244","wikidata":"https://www.wikidata.org/wiki/Q506441","display_name":"Hapten","level":3,"score":0.8249006271362305},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5482965707778931},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20332738757133484},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.14576691389083862},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.11577939987182617},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.09274664521217346},{"id":"https://openalex.org/C544153396","wikidata":"https://www.wikidata.org/wiki/Q11426","display_name":"Metal","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000345","descriptor_name":"Affinity Labels","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000936","descriptor_name":"Antigen-Antibody Complex","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003998","descriptor_name":"Dicarboxylic Acids","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006241","descriptor_name":"Haptens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008722","descriptor_name":"Methods","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009596","descriptor_name":"Nitrophenols","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0076-6879(77)46060-9","doi":"https://doi.org/10.1016/s0076-6879(77)46060-9","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0076-6879(77)46060-9","pdf_url":null,"source":{"id":"https://openalex.org/S182211142","display_name":"Methods in enzymology on CD-ROM/Methods in enzymology","issn_l":"0076-6879","issn":["0076-6879","1079-2376","1557-7988"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319955","host_organization_name":"Academic Press","host_organization_lineage":["https://openalex.org/P4310319955","https://openalex.org/P4310320990"],"host_organization_lineage_names":["Academic Press","Elsevier BV"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in Enzymology","raw_type":"book-chapter"},{"id":"pmid:561876","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/561876","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in enzymology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W1990344075","https://openalex.org/W1997250042","https://openalex.org/W1998421692","https://openalex.org/W2028232536","https://openalex.org/W2031331955","https://openalex.org/W2057550325","https://openalex.org/W4235753237"],"related_works":["https://openalex.org/W2006040039","https://openalex.org/W1966263386","https://openalex.org/W2028232536","https://openalex.org/W1978881873","https://openalex.org/W1553512865","https://openalex.org/W2087695868","https://openalex.org/W1983435795","https://openalex.org/W2021353715","https://openalex.org/W2013518947","https://openalex.org/W1969043569"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}