{"id":"https://openalex.org/W2210968261","doi":"https://doi.org/10.1016/j.jacc.2010.09.043","title":"Use of Mouse Models to Evaluate Novel Therapeutic Approaches to Treatment of Arrhythmogenic Right Ventricular Cardiomyopathy","display_name":"Use of Mouse Models to Evaluate Novel Therapeutic Approaches to Treatment of Arrhythmogenic Right Ventricular Cardiomyopathy","publication_year":2011,"publication_date":"2011-02-01","ids":{"openalex":"https://openalex.org/W2210968261","doi":"https://doi.org/10.1016/j.jacc.2010.09.043","mag":"2210968261","pmid":"https://pubmed.ncbi.nlm.nih.gov/21292135"},"language":"en","primary_location":{"id":"doi:10.1016/j.jacc.2010.09.043","doi":"https://doi.org/10.1016/j.jacc.2010.09.043","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jacc.2010.09.043","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0735109710046516/pdf","source":{"id":"https://openalex.org/S60865174","display_name":"Journal of the American College of Cardiology","issn_l":"0735-1097","issn":["0735-1097","1558-3597"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"journal-article"},"volume":null,"type":"editorial","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.sciencedirect.com/science/article/pii/S0735109710046516/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025889874","display_name":"Hugh G Calkins","orcid":"https://orcid.org/0000-0002-9262-9433","observed_orcids":["https://orcid.org/0000-0002-9262-9433"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Hugh Calkins","raw_affiliation_strings":["Electrophysiology and Arrhythmia Service, Division of Cardiology, Department of Internal Medicine, Johns Hopkins University, Baltimore, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Electrophysiology and Arrhythmia Service, Division of Cardiology, Department of Internal Medicine, Johns Hopkins University, Baltimore, Maryland","institution_ids":["https://openalex.org/I145311948"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5025889874"],"corresponding_institution_ids":["https://openalex.org/I145311948"],"apc_list":{"value":7166,"currency":"USD","value_usd":7166},"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"57","issue":"6","first_page":"751","last_page":"752"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11922","display_name":"Cardiovascular Effects of Exercise","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11922","display_name":"Cardiovascular Effects of Exercise","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.007000000216066837,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.004600000102072954,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/arrhythmogenic-right-ventricular-cardiomyopathy","display_name":"arrhythmogenic right ventricular cardiomyopathy","score":0.9950000047683716},{"id":"https://openalex.org/keywords/mouse-model","display_name":"mouse model","score":0.9679999947547913},{"id":"https://openalex.org/keywords/inherited-cardiomyopathy","display_name":"familial cardiomyopathy","score":0.8830000162124634},{"id":"https://openalex.org/keywords/ventricular-arrhythmias","display_name":"ventricular arrhythmias","score":0.9559999704360962},{"id":"https://openalex.org/keywords/sudden-cardiac-death","display_name":"sudden cardiac death","score":0.9850000143051147},{"id":"https://openalex.org/keywords/therapeutic-target","display_name":"therapeutic target","score":0.4090000092983246}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9734632968902588},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6339244842529297},{"id":"https://openalex.org/C2778797674","wikidata":"https://www.wikidata.org/wiki/Q847583","display_name":"Cardiomyopathy","level":3,"score":0.6109121441841125},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5648519992828369},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.21599683165550232}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002306","descriptor_name":"Cardiac Volume","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D004232","descriptor_name":"Diuretics","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005665","descriptor_name":"Furosemide","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D009566","descriptor_name":"Nitrates","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D017725","descriptor_name":"Ventricular Pressure","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D019571","descriptor_name":"Arrhythmogenic Right Ventricular Dysplasia","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jacc.2010.09.043","doi":"https://doi.org/10.1016/j.jacc.2010.09.043","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jacc.2010.09.043","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0735109710046516/pdf","source":{"id":"https://openalex.org/S60865174","display_name":"Journal of the American College of Cardiology","issn_l":"0735-1097","issn":["0735-1097","1558-3597"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"journal-article"},{"id":"pmid:21292135","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21292135","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"Editorial"}],"best_oa_location":{"id":"doi:10.1016/j.jacc.2010.09.043","doi":"https://doi.org/10.1016/j.jacc.2010.09.043","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jacc.2010.09.043","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0735109710046516/pdf","source":{"id":"https://openalex.org/S60865174","display_name":"Journal of the American College of Cardiology","issn_l":"0735-1097","issn":["0735-1097","1558-3597"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American College of Cardiology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332389","display_name":"St. Jude Medical","ror":"https://ror.org/00t9de449"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2210968261.pdf","grobid_xml":"https://content.openalex.org/works/W2210968261.grobid-xml"},"referenced_works_count":11,"referenced_works":["https://openalex.org/W1969774384","https://openalex.org/W1972265503","https://openalex.org/W2032094196","https://openalex.org/W2033551834","https://openalex.org/W2036211423","https://openalex.org/W2052675296","https://openalex.org/W2089090129","https://openalex.org/W2102339256","https://openalex.org/W2121220509","https://openalex.org/W2131810639","https://openalex.org/W2405693981"],"related_works":["https://openalex.org/W3112108943","https://openalex.org/W102621638","https://openalex.org/W4417257136","https://openalex.org/W2335926476","https://openalex.org/W2058324819","https://openalex.org/W2918981893","https://openalex.org/W4238305081","https://openalex.org/W2007634115","https://openalex.org/W2092900376","https://openalex.org/W2141994630"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}