{"id":"https://openalex.org/W221055069","doi":null,"title":"Metal-cell interactions: investigation of the mode of toxicity of copper to microalgae in plankton and biofilms","display_name":"Metal-cell interactions: investigation of the mode of toxicity of copper to microalgae in plankton and biofilms","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W221055069","mag":"221055069"},"language":"en","primary_location":{"id":"pmh:oai:ro.uow.edu.au:theses-4402","doi":null,"is_oa":false,"landing_page_url":"https://ro.uow.edu.au/theses/3401","pdf_url":null,"source":{"id":"https://openalex.org/S4306400510","display_name":"Research Online (University of Wollongong)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I204824540","host_organization_name":"University of Wollongong","host_organization_lineage":["https://openalex.org/I204824540"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"University of Wollongong Thesis Collection 1954-2016","raw_type":"thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021644151","display_name":"Jacqueline L. Levy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204824540","display_name":"University of Wollongong","ror":"https://ror.org/00jtmb277","country_code":"AU","type":"education","lineage":["https://openalex.org/I204824540"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Jacqueline L. Levy","raw_affiliation_strings":["University of Wollongong"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Wollongong","institution_ids":["https://openalex.org/I204824540"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5021644151"],"corresponding_institution_ids":["https://openalex.org/I204824540"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10447","display_name":"Environmental Toxicology and Ecotoxicology","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10447","display_name":"Environmental Toxicology and Ecotoxicology","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12071","display_name":"Marine Biology and Environmental Chemistry","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2212","display_name":"Ocean Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10236","display_name":"Aquatic Ecosystems and Phytoplankton Dynamics","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2304","display_name":"Environmental Chemistry"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microalgae","display_name":"microalgae","score":0.9769999980926514},{"id":"https://openalex.org/keywords/biofilm","display_name":"biofilm","score":0.7310000061988831},{"id":"https://openalex.org/keywords/plankton","display_name":"plankton","score":0.9089999794960022},{"id":"https://openalex.org/keywords/copper-uptake","display_name":"copper uptake","score":0.550000011920929},{"id":"https://openalex.org/keywords/partition-coefficient","display_name":"partition coefficient","score":0.5669999718666077},{"id":"https://openalex.org/keywords/cell-size","display_name":"cell size","score":0.5720000267028809},{"id":"https://openalex.org/keywords/cell-wall-ultrastructure","display_name":"cell wall ultrastructure","score":0.890999972820282},{"id":"https://openalex.org/keywords/species-sensitivity","display_name":"species sensitivity","score":0.3919999897480011},{"id":"https://openalex.org/keywords/dunaliella-tertiolecta","display_name":"Dunaliella tertiolecta","score":0.8230000138282776},{"id":"https://openalex.org/keywords/cell-ultrastructure","display_name":"cell ultrastructure","score":0.5249999761581421},{"id":"https://openalex.org/keywords/metal-detoxification","display_name":"metal detoxification","score":0.35100001096725464}],"concepts":[{"id":"https://openalex.org/C108469399","wikidata":"https://www.wikidata.org/wiki/Q25367","display_name":"Plankton","level":2,"score":0.7404932975769043},{"id":"https://openalex.org/C544778455","wikidata":"https://www.wikidata.org/wiki/Q753","display_name":"Copper","level":2,"score":0.6922473311424255},{"id":"https://openalex.org/C58123911","wikidata":"https://www.wikidata.org/wiki/Q467410","display_name":"Biofilm","level":3,"score":0.6033065915107727},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.538063645362854},{"id":"https://openalex.org/C2778302132","wikidata":"https://www.wikidata.org/wiki/Q4215775","display_name":"Metal toxicity","level":3,"score":0.4964292645454407},{"id":"https://openalex.org/C107872376","wikidata":"https://www.wikidata.org/wiki/Q321355","display_name":"Environmental chemistry","level":1,"score":0.4855913519859314},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.44811397790908813},{"id":"https://openalex.org/C39432304","wikidata":"https://www.wikidata.org/wiki/Q188847","display_name":"Environmental science","level":0,"score":0.4203876554965973},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.349273681640625},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.30843430757522583},{"id":"https://openalex.org/C2776053758","wikidata":"https://www.wikidata.org/wiki/Q105789","display_name":"Heavy metals","level":2,"score":0.3077540397644043},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2843945026397705},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:ro.uow.edu.au:theses-4402","doi":null,"is_oa":false,"landing_page_url":"https://ro.uow.edu.au/theses/3401","pdf_url":null,"source":{"id":"https://openalex.org/S4306400510","display_name":"Research Online (University of Wollongong)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I204824540","host_organization_name":"University of Wollongong","host_organization_lineage":["https://openalex.org/I204824540"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"University of Wollongong Thesis Collection 1954-2016","raw_type":"thesis"},{"id":"pmh:oai:figshare.com:article/27661293","doi":null,"is_oa":false,"landing_page_url":"https://figshare.com/articles/thesis/Metal-cell_interactions_investigation_of_the_mode_of_toxicity_of_copper_to_microalgae_in_plankton_and_biofilms/27661293","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Thesis"},{"id":"mag:221055069","doi":null,"is_oa":false,"landing_page_url":"https://ro.uow.edu.au/cgi/viewcontent.cgi?article=4402&context=theses","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":98,"referenced_works":["https://openalex.org/W16965521","https://openalex.org/W66535486","https://openalex.org/W586358893","https://openalex.org/W1004829090","https://openalex.org/W1246100206","https://openalex.org/W1482129608","https://openalex.org/W1491340377","https://openalex.org/W1492617550","https://openalex.org/W1526320464","https://openalex.org/W1571698813","https://openalex.org/W1878254292","https://openalex.org/W1926389685","https://openalex.org/W1969886952","https://openalex.org/W1974454653","https://openalex.org/W1977149896","https://openalex.org/W1978151446","https://openalex.org/W1982160607","https://openalex.org/W1982269094","https://openalex.org/W1984006517","https://openalex.org/W1985694301","https://openalex.org/W1986376122","https://openalex.org/W1986898384","https://openalex.org/W1988158299","https://openalex.org/W1989537542","https://openalex.org/W1996403178","https://openalex.org/W1997325343","https://openalex.org/W1997493014","https://openalex.org/W1998649751","https://openalex.org/W2002173519","https://openalex.org/W2008190750","https://openalex.org/W2008623746","https://openalex.org/W2009164211","https://openalex.org/W2011364286","https://openalex.org/W2013774941","https://openalex.org/W2015441111","https://openalex.org/W2015715459","https://openalex.org/W2019138421","https://openalex.org/W2021221294","https://openalex.org/W2024772676","https://openalex.org/W2033965857","https://openalex.org/W2034306040","https://openalex.org/W2037541581","https://openalex.org/W2037825672","https://openalex.org/W2047988525","https://openalex.org/W2048899172","https://openalex.org/W2052293046","https://openalex.org/W2053778452","https://openalex.org/W2054004222","https://openalex.org/W2054385611","https://openalex.org/W2061213182","https://openalex.org/W2063509957","https://openalex.org/W2072059447","https://openalex.org/W2072116693","https://openalex.org/W2074213856","https://openalex.org/W2077805719","https://openalex.org/W2082630861","https://openalex.org/W2086942492","https://openalex.org/W2088280037","https://openalex.org/W2092708409","https://openalex.org/W2092731805","https://openalex.org/W2096756074","https://openalex.org/W2101884722","https://openalex.org/W2104467958","https://openalex.org/W2108938757","https://openalex.org/W2109842871","https://openalex.org/W2112969093","https://openalex.org/W2113892199","https://openalex.org/W2118654926","https://openalex.org/W2119152927","https://openalex.org/W2123089666","https://openalex.org/W2125040423","https://openalex.org/W2130141774","https://openalex.org/W2133831814","https://openalex.org/W2138582996","https://openalex.org/W2139145635","https://openalex.org/W2139504675","https://openalex.org/W2139639179","https://openalex.org/W2143707536","https://openalex.org/W2146890671","https://openalex.org/W2150413334","https://openalex.org/W2150931933","https://openalex.org/W2155670231","https://openalex.org/W2157859508","https://openalex.org/W2158185109","https://openalex.org/W2160446311","https://openalex.org/W2160884217","https://openalex.org/W2167590255","https://openalex.org/W2168778829","https://openalex.org/W2169277573","https://openalex.org/W2170498142","https://openalex.org/W2170728970","https://openalex.org/W2246895013","https://openalex.org/W2500823084","https://openalex.org/W2504092510","https://openalex.org/W2569066005","https://openalex.org/W2804078503","https://openalex.org/W4241523079","https://openalex.org/W4244010491"],"related_works":["https://openalex.org/W2016963475","https://openalex.org/W958010025","https://openalex.org/W652028056","https://openalex.org/W4391383770","https://openalex.org/W2059930917","https://openalex.org/W2156455817","https://openalex.org/W2112435953","https://openalex.org/W2119878191","https://openalex.org/W2792376482","https://openalex.org/W2015869197"],"abstract_inverted_index":{"Microalgae":[0],"are":[1,17,40,51,1174,1186],"sensitive":[2,242,412],"indicators":[3],"of":[4,11,23,28,57,99,104,116,132,140,160,181,189,204,231,263,280,313,419,533,552,601,620,646,662,703,722,734,745,749,773,810,841,862,865,872,886,893,899,954,985,1009,1017,1032,1041,1057,1106,1149,1218,1232,1275,1287,1298,1312,1328,1351,1376,1384,1420,1456,1481],"environmental":[5,29,58,102],"change":[6],"and,":[7],"as":[8,81,83,228,664,912,962,1101,1115,1179,1367],"the":[9,21,26,72,89,97,117,130,138,219,229,240,249,296,365,378,425,490,495,531,553,611,615,628,642,704,743,770,805,832,839,863,870,923,928,952,955,963,967,980,999,1015,1019,1034,1079,1083,1094,1147,1176,1180,1216,1219,1228,1266,1269,1283,1288,1296,1305,1326,1337,1349,1374,1404,1421,1423],"basis":[10],"most":[12,241],"freshwater":[13,929],"and":[14,25,44,77,91,121,123,134,150,154,178,195,234,246,265,286,292,298,331,390,435,472,518,537,562,585,599,644,699,713,732,766,826,905,914,934,946,982,1038,1044,1103,1136,1157,1183,1230,1247,1372,1390,1453],"marine":[15,182,205,818,924,1122,1234,1277],"ecosystems,":[16],"widely":[18],"used":[19,921,1213],"in":[20,36,69,71,88,96,162,336,354,361,369,374,392,395,545,559,610,614,618,627,635,641,671,724,742,777,783,790,812,831,835,853,951,1014,1077,1152,1169,1192,1227,1304,1333,1407,1415,1431,1448,1489,1499],"assessment":[22,1171],"risk":[24],"development":[27],"regulations":[30],"for":[31,54,142,277,669,684,708,816,979,991,1268,1386,1409],"metals.":[32],"However,":[33,324,747,1362],"inter-species":[34],"differences":[35,335,360,368,544,1151],"sensitivity":[37,180,338,355,840,871,1023,1154,1217,1408,1416],"to":[38,94,152,213,218,244,257,342,359,402,413,424,505,565,569,608,652,680,726,759,779,844,875,959,965,1025,1111,1214,1225,1250,1254,1279,1295,1330,1344,1437,1442,1445,1460],"metals":[39,120],"not":[41,67,340,625,658,793,802,848,976,1087,1301,1468],"well":[42,82,1401],"understood":[43],"laboratory-based":[45],"toxicity":[46,105,166,815,855,1162,1280,1327,1447,1472],"tests":[47,106,1163,1281,1391],"with":[48,75,165,252,308,316,399,415,890,901,1121,1336,1373,1392],"planktonic":[49],"microalgae":[50,183,887],"often":[52],"criticised":[53],"their":[55,827],"lack":[56],"relevance.":[59],"One":[60],"such":[61,227],"criticism":[62],"is":[63,127,147,157,847,1458],"that":[64,483,530,719,764,797,1073,1159],"algae":[65,122,206,281,427,825,874,900,920],"do":[66],"exist":[68],"isolation":[70],"field,":[73],"interacting":[74],"bacteria":[76,133,908,1018,1074,1095,1112,1173],"other":[78,629],"algal":[79,397,546,555,672,842,879,1080,1181],"species,":[80],"higher":[84,451,649],"order":[85],"organisms,":[86],"both":[87,148,1033],"plankton":[90,833],"when":[92],"attached":[93,1249,1441],"substrates":[95],"form":[98],"biofilms.":[100,135,1235],"The":[101,172,290,406,549,631,660,808,918,1029,1124,1273,1310],"relevance":[103],"could":[107],"be":[108,357,1402,1461],"improved":[109,1282],"by":[110,129,224,261,970,1061,1381],"having":[111,512],"a":[112,158,187,283,304,309,416,513,665,897,915,1006,1104,1368,1382,1449,1476,1492],"better":[113,506,950],"fundamental":[114],"understanding":[115],"interactions":[118,1191],"between":[119,174,329,377,824,1155],"how":[124],"this":[125,143,774,1399,1454],"relationship":[126,173,326],"affected":[128],"presence":[131,953,1016,1231],"Copper":[136,270],"was":[137,184,222,239,327,410,557,657,674,730,792,975,1049,1071,1417,1425,1435,1487],"metal":[139,1170,1199],"choice":[141],"research":[144],"because":[145,155],"it":[146,156],"essential":[149],"toxic":[151],"microalgae,":[153],"contaminant":[159],"concern":[161],"aquatic":[163],"environments,":[164],"occurring":[167],"at":[168,494,523,769,1315],"low":[169],"\u00b5g/L":[170],"concentrations.":[171,526],"metal-algal":[175],"cell":[176,220,232,235,285,318,343,345,393,550,616,771,1182,1240,1316,1355,1465,1479],"binding":[177,371],"copper":[179,216,245,332,337,385,403,453,488,498,508,515,521,535,566,670,690,706,814,876,960,1153,1226,1329],"investigated":[185,384,675,1050],"using":[186,591,877,1051,1064,1364],"series":[188],"72-h":[190,253,417,757,878,1007,1207,1270,1338],"growth":[191,259,880,968,1208,1285],"rate":[192,260,517,881,969,1209,1286],"inhibition":[193,619,882,1210],"bioassays":[194,1211,1438],"short-term":[196],"(1-h)":[197],"uptake":[198,362,539],"studies":[199],"(Chapter":[200,404,596,676],"3).":[201],"A":[202,380,1412],"range":[203],"from":[207,1175,1265,1342],"different":[208,978],"taxonomic":[209,348],"groups":[210],"were":[211,275,339,624,638,692,801,888,922,1075,1086,1097,1212,1252,1262,1370,1501],"screened":[212],"determine":[214],"whether":[215],"adsorption":[217],"membrane":[221],"influenced":[223],"biotic":[225],"factors,":[226],"ultrastructure":[230,394,551],"walls":[233],"size.":[236],"Minutocellus":[237],"polymorphus":[238],"species":[243,279,398,547,556,819,843,885,895,1118,1221,1290],"Dunaliella":[247,436],"tertiolecta":[248,437,474,503,755],"least":[250],"sensitive,":[251],"IC50":[254,418,431,439,445,572,1008,1020,1339],"values":[255],"(concentration":[256],"inhibit":[258,966],"50%)":[262],"0.6":[264],"530":[266,440],"\u00b5g":[267,421,433,441,576,581,587,682,728,761,1011,1027,1346],"Cu/L,":[268,422,1012],"respectively.":[269,716],"solution-cell":[271],"partition":[272],"coefficients":[273],"(Kd)":[274],"calculated":[276],"six":[278],"on":[282,869,1091,1138,1202],"per":[284],"surface":[287,305,319,772],"area":[288,306,320],"basis.":[289],"largest":[291],"smallest":[293],"cells":[294,561,563,604,637,673,1261],"had":[295,449,1005,1108],"lowest":[297],"highest":[299],"Kd":[300,315,330,351],"values,":[301,446],"respectively":[302],"(on":[303],"basis),":[307],"general":[310],"(non-linear)":[311],"trend":[312],"decreasing":[314],"increasing":[317,1341],"(p":[321],"=":[322],"0.026).":[323],"no":[325,902,906],"found":[328,1072],"sensitivity.":[333,548],"Interspecies":[334],"related":[341,607],"size,":[344],"wall":[346],"type,":[347],"group":[349],"or":[350,654,788,834,990,1117,1189,1194,1428],"values.":[352],"Variation":[353],"may":[356,837,1196,1400],"due":[358,1294],"rates":[363,540],"across":[364],"plasma":[366,653],"membrane,":[367],"internal":[370,520,534],"processes":[372],"and/or":[373],"detoxification":[375,667],"mechanisms":[376],"species.":[379,630],"more":[381,1450,1462],"in-depth":[382],"study":[383],"adsorption,":[386],"internalisation,":[387],"exudate":[388,740],"production":[389,661,721,741],"changes":[391,609,623,633],"three":[396,554],"differing":[400],"sensitivities":[401],"4).":[405,597,677],"diatom":[407,925,1494],"Phaeodactylum":[408],"tricornutum":[409,464,603],"particularly":[411],"copper,":[414],"8.0":[420],"compared":[423],"green":[426,930],"Tetraselmis":[428,447,484,510,711,1222,1259,1331,1377,1410],"sp.":[429,448,485,712,993,1002,1046,1223,1260,1332,1378,1411],"(72-h":[430,438],"47":[432],"Cu/L)":[434],"Cu/L).":[442],"At":[443,648,996],"these":[444,636,817],"much":[450],"intracellular":[452],"concentrations":[454,522,536,567,691,707,768],"(1.97":[455],"\u00b1":[456,466,476,694,697,701],"0.01":[457],"\uf0b4":[458,468,478,1243,1320,1358,1395,1483],"10-13":[459,469,479],"g":[460,470,480],"Cu/cell)":[461,471],"than":[462,509,1131],"P.":[463,602,709,947,988],"(0.23":[465],"0.19":[467],"D.":[473,502,714,754],"(0.59":[475],"0.05":[477],"Cu/cell),":[481],"suggesting":[482,796],"effectively":[486,1324],"detoxifies":[487],"within":[489,1403],"cell.":[491],"By":[492],"contrast,":[493],"same":[496,1177],"external":[497],"concentration":[499,964],"(50":[500],"\u00b5g/L),":[501],"appears":[504],"exclude":[507],"sp.,":[511],"slower":[514],"internalisation":[516],"lower":[519],"equivalent":[524,1133],"extracellular":[525],"These":[527],"results":[528,1363],"suggest":[529],"use":[532,1166],"net":[538],"alone":[541],"cannot":[542],"explain":[543],"examined":[558],"control":[560,735,940,1284],"exposed":[564],"similar":[568,1413],"each":[570,894],"species\u2019":[571],"value,":[573],"i.e.":[574,1082],"15":[575,1482],"Cu/L":[577,582,588,683,729,762,1347],"(P.":[578],"tricornutum),":[579],"50":[580,681,727],"(Tetraselmis":[583,1291],"sp.)":[584],"500":[586,760],"(D.":[589],"tertiolecta)":[590],"transmission":[592],"electron":[593],"microscopy":[594],"(TEM)":[595],"Swelling":[598],"clumping":[600],"occurred,":[605],"potentially":[606],"glutathione":[612],"ratio":[613],"resulting":[617],"mitosis.":[621],"Size":[622],"evident":[626],"main":[632],"observed":[634,1418],"an":[639,860,1132],"increase":[640,782,1469],"size":[643],"number":[645,1105],"vacuoles.":[647],"magnification,":[650],"disruption":[651],"thykaloid":[655],"membranes":[656],"observed.":[659],"exudates":[663,723,811],"potential":[666],"mechanism":[668],"Following":[678],"exposure":[679,758],"72-h,":[685],"anodic":[686],"stripping":[687],"voltammetry":[688],"(ASV)-labile":[689],"92":[693],"9%,":[695],"94":[696],"9%":[698],"114":[700],"3%":[702],"dissolved":[705],"tricornutum,":[710],"tertiolecta,":[715],"This":[717,1145],"suggests":[718,1158],"major":[720],"response":[725,778],"unlikely,":[731],"analysis":[733],"samples":[736],"also":[737,1140],"suggested":[738,763],"limited":[739],"absence":[744,1229],"copper.":[746,780],"examination":[748],"spent":[750],"test":[751,806,1220,1271,1289,1308,1473],"media":[752],"containing":[753],"after":[756,972],"carbohydrate":[765],"protein":[767,787],"alga":[775,931],"increased":[776,1021],"An":[781],"organic":[784],"matter":[785],"(as":[786],"carbohydrate)":[789],"solution":[791],"detected":[794],"however,":[795],"any":[798],"additional":[799],"ligands":[800],"excreted":[803],"into":[804,851],"medium.":[807,1309],"role":[809],"ameliorating":[813],"requires":[820],"further":[821],"research.":[822],"Interactions":[823],"associated":[828,1120],"bacteria,":[829],"either":[830],"biofilms,":[836],"alter":[838],"contaminants,":[845],"which":[846,1432,1490],"currently":[849],"taken":[850],"account":[852],"laboratory":[854,1471],"tests.":[856],"Chapter":[857,1205],"5":[858],"describes":[859],"investigation":[861],"effects":[864],"simple":[866],"algal-bacterial":[867],"relationships":[868],"laboratory-cultured":[873],"bioassays.":[883,1255],"Four":[884],"used,":[889,1488],"two":[891,935,1385],"isolates":[892,1107],"tested;":[896],"strain":[898],"microscopically":[903],"visible":[904],"culturable":[907],"present":[909,1076,1096],"(operationally":[910],"defined":[911,1036],"axenic)":[913],"non-axenic":[916,983,1039,1134,1167],"strain.":[917],"four":[919],"Nitzschia":[926],"closterium,":[927,987],"Pseudokirchneriella":[932],"subcapitata":[933,948,989],"tropical":[936],"Chlorella":[937,992,1001,1045],"spp.":[938],"Under":[939],"conditions":[941,1474],"(no":[942,1388],"copper),":[943],"N.":[944,986,1042],"closterium":[945,1043],"grew":[949,1495],"bacterial":[956,1030,1129,1143,1184],"community.":[957],"Sensitivity":[958],"(assessed":[961],"50%":[971],"72":[973],"h)":[974],"significantly":[977,1340],"axenic":[981,1000,1037,1084],"strains":[984],"(PNG":[994],"isolate).":[995],"pH":[997],"5.7,":[998],"(NT":[1003,1047],"isolate)":[1004,1048],"46":[1010],"while":[1013,1439],"(i.e.,":[1022],"decreased)":[1024],"208":[1026],"Cu/L.":[1028],"status":[1031],"operationally":[1035],"cultures":[1040,1085,1126,1168],"polymerase":[1052],"chain":[1053],"reaction":[1054],"(PCR)":[1055],"amplification":[1056],"16S":[1058],"rDNA":[1059],"followed":[1060],"DNA":[1062],"fingerprinting":[1063],"denaturing":[1065],"gradient":[1066],"gel":[1067],"electrophoresis":[1068],"(DGGE).":[1069],"It":[1070],"all":[1078,1099],"cultures,":[1081],"truly":[1088],"bacteria-free.":[1089],"Based":[1090],"sequence":[1092],"information,":[1093],"nearly":[1098],"identified":[1100,1114],"alphaproteobacteria":[1102],"high":[1109],"similarity":[1110],"previously":[1113],"symbionts":[1116],"endophytically":[1119],"organisms.":[1123],"\u201caxenic\u201d":[1125],"contained":[1127,1141],"less":[1128,1142],"phylotypes":[1130],"culture,":[1135],"based":[1137],"band-intensity,":[1139],"DNA.":[1144],"supported":[1146],"findings":[1148],"few":[1150],"strains,":[1156],"standard":[1160],"microalgal":[1161],"probably":[1164,1293],"inadvertently":[1165],"where":[1172],"environment":[1178],"numbers":[1185],"low.":[1187],"Cell-cell":[1188],"cell-exudate":[1190],"biofilms":[1193,1248,1278,1393],"periphyton":[1195],"help":[1197],"alleviate":[1198],"stress":[1200],"exerted":[1201],"microalgae.":[1203],"In":[1204],"6,":[1206],"assess":[1215],"(Prasinophyceae)":[1224],"field-collected":[1233,1276],"Harvested":[1236],"biofilm":[1237,1267,1313,1352,1354,1365,1424,1433],"homogenate":[1238,1369],"(initial":[1239,1353],"density":[1241,1480],"1.5-15":[1242],"104":[1244,1321,1359,1396,1484],"fluorescent":[1245,1322,1360,1397,1485],"cells/mL)":[1246],"slides":[1251,1443],"added":[1253,1366,1436],"Using":[1256],"flow":[1257],"cytometry,":[1258],"easily":[1263],"distinguished":[1264],"duration.":[1272],"addition":[1274,1311,1350],"sp.),":[1292],"provision":[1297],"extra":[1299],"nutrients":[1300],"otherwise":[1302],"available":[1303],"minimal":[1306],"nutrient":[1307],"material":[1314,1434],"densities":[1317,1466],"\uf0b3":[1318],"6":[1319,1357],"cells/mL":[1323,1486],"ameliorated":[1325],"some":[1334],"tests,":[1335],"43":[1343],"67":[1345],"upon":[1348,1504],"density,":[1356],"cells/mL).":[1361],"variable":[1371],"copper-sensitivity":[1375],"varying":[1379],"only":[1380],"factor":[1383],"controls":[1387],"biofilm)":[1389],"(1.5-15":[1394],"cells/mL),":[1398],"natural":[1405],"variation":[1406],"decrease":[1414],"regardless":[1419],"season":[1422],"collected":[1426,1498],"(winter":[1427],"spring).":[1429],"Tests":[1430],"still":[1440],"appeared":[1444],"ameliorate":[1446],"consistent":[1451],"fashion,":[1452],"type":[1455],"bioassay":[1457],"likely":[1459],"appropriate.":[1463],"Biofilm":[1464],"did":[1467],"under":[1470],"unless":[1475],"critical":[1477],"initial":[1478],"case":[1491],"centric":[1493],"rapidly.":[1496],"Biofilms":[1497],"spring":[1500],"visibly":[1502],"thicker":[1503],"collection":[1505]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
