{"id":"https://openalex.org/W2210160087","doi":null,"title":"Resistance following chronic HIV-1 exposure is associated with increased virus-driven IFN gamma and reduced IL-4 synthesis, independent of changes in other Th2-associated cytokines.","display_name":"Resistance following chronic HIV-1 exposure is associated with increased virus-driven IFN gamma and reduced IL-4 synthesis, independent of changes in other Th2-associated cytokines.","publication_year":2003,"publication_date":"2003-01-01","ids":{"openalex":"https://openalex.org/W2210160087","mag":"2210160087"},"language":"en","primary_location":{"id":"mag:2210160087","doi":null,"is_oa":false,"landing_page_url":"http://erepository.uonbi.ac.ke/handle/11295/50313","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042926974","display_name":"HN Trivedi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"HN Trivedi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007459903","display_name":"Aggrey Omu Anzala","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aggrey O. Anzala","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059345380","display_name":"Ephantus Njagi","orcid":"https://orcid.org/0000-0002-1484-0241","observed_orcids":["https://orcid.org/0000-0002-1484-0241"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E.N.M. Njagi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1484-0241","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111876549","display_name":"J. J. Bwayo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"JJ Bwayo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069964336","display_name":"ELIZABETH N. NGUGI","orcid":"https://orcid.org/0000-0001-5835-2752","observed_orcids":["https://orcid.org/0000-0001-5835-2752"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elizabeth Ngugi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5835-2752","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072841776","display_name":"Kent T. HayGlass","orcid":"https://orcid.org/0000-0002-4621-7737","observed_orcids":["https://orcid.org/0000-0002-4621-7737"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kent T. HayGlass","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-4621-7737","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5064970400","display_name":"F. A. Plummer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F. A. Plummer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hiv-1","display_name":"HIV-1","score":0.7940000295639038},{"id":"https://openalex.org/keywords/chronic-hiv-infection","display_name":"chronic HIV infection","score":0.7710000276565552},{"id":"https://openalex.org/keywords/hiv-drug-resistance","display_name":"HIV drug resistance","score":0.3790000081062317},{"id":"https://openalex.org/keywords/interferon-gamma","display_name":"interferon-gamma","score":0.6890000104904175},{"id":"https://openalex.org/keywords/il-4","display_name":"IL-4","score":0.9039999842643738},{"id":"https://openalex.org/keywords/th2-cytokines","display_name":"Th2 cytokines","score":0.972000002861023},{"id":"https://openalex.org/keywords/th1-th2-balance","display_name":"Th1/Th2 balance","score":0.7760000228881836},{"id":"https://openalex.org/keywords/immune-response-to-hiv","display_name":"immune response to HIV","score":0.4950000047683716}],"concepts":[{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.6124142408370972},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5275958180427551},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.4926760792732239},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4537217915058136},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.4432598650455475}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2210160087","doi":null,"is_oa":false,"landing_page_url":"http://erepository.uonbi.ac.ke/handle/11295/50313","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W6980533307","https://openalex.org/W2106874119","https://openalex.org/W2015471095","https://openalex.org/W1813961829","https://openalex.org/W2046813477","https://openalex.org/W2901031007","https://openalex.org/W2077736967","https://openalex.org/W1530102271","https://openalex.org/W2001114840","https://openalex.org/W1982857233"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-25T08:18:29.962427","created_date":"2016-06-24T00:00:00"}