{"id":"https://openalex.org/W2208515426","doi":null,"title":"The Inter-Relation of the Cardio-Autonomic Nervous System and HPA-Axis and its Association with Cardiovascular Precursors in Children","display_name":"The Inter-Relation of the Cardio-Autonomic Nervous System and HPA-Axis and its Association with Cardiovascular Precursors in Children","publication_year":2015,"publication_date":"2015-09-01","ids":{"openalex":"https://openalex.org/W2208515426","mag":"2208515426"},"language":"en","primary_location":{"id":"pmh:oai:https://spectrum.library.concordia.ca:980481","doi":null,"is_oa":true,"landing_page_url":"https://spectrum.library.concordia.ca/980481/1/Rotenberg_PhD_F2015.pdf","pdf_url":"https://spectrum.library.concordia.ca/980481/1/Rotenberg_PhD_F2015.pdf","source":{"id":"https://openalex.org/S4306400871","display_name":"Spectrum Research Repository (Concordia University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I60158472","host_organization_name":"Concordia University","host_organization_lineage":["https://openalex.org/I60158472"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://spectrum.library.concordia.ca/980481/1/Rotenberg_PhD_F2015.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037039254","display_name":"Sivan Rotenberg","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Sivan Rotenberg","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5037039254"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.7554000020027161,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.7554000020027161,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.22660000622272491,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypothalamic-pituitary-adrenal-axis","display_name":"hypothalamic-pituitary-adrenal axis","score":0.9110000133514404},{"id":"https://openalex.org/keywords/stress-response-system","display_name":"stress system","score":0.906000018119812},{"id":"https://openalex.org/keywords/stress-exposure","display_name":"stress exposure","score":0.49300000071525574},{"id":"https://openalex.org/keywords/stressful-life-events","display_name":"life events","score":0.9279999732971191},{"id":"https://openalex.org/keywords/children","display_name":"children","score":0.5519999861717224},{"id":"https://openalex.org/keywords/adolescents","display_name":"adolescents","score":0.9390000104904175},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.43700000643730164},{"id":"https://openalex.org/keywords/cardiovascular-health","display_name":"cardiovascular health","score":0.656000018119812}],"concepts":[{"id":"https://openalex.org/C2777372248","wikidata":"https://www.wikidata.org/wiki/Q171064","display_name":"Autonomic nervous system","level":4,"score":0.6937116980552673},{"id":"https://openalex.org/C142853389","wikidata":"https://www.wikidata.org/wiki/Q744778","display_name":"Association (psychology)","level":2,"score":0.6831472516059875},{"id":"https://openalex.org/C21036866","wikidata":"https://www.wikidata.org/wiki/Q181767","display_name":"Stress (linguistics)","level":2,"score":0.6043580770492554},{"id":"https://openalex.org/C78604142","wikidata":"https://www.wikidata.org/wiki/Q1640582","display_name":"Fight-or-flight response","level":3,"score":0.49879980087280273},{"id":"https://openalex.org/C76709773","wikidata":"https://www.wikidata.org/wiki/Q7623445","display_name":"Stress measures","level":3,"score":0.4911007881164551},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4895404279232025},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.48125573992729187},{"id":"https://openalex.org/C125370674","wikidata":"https://www.wikidata.org/wiki/Q1527480","display_name":"Stressor","level":2,"score":0.45306122303009033},{"id":"https://openalex.org/C25343380","wikidata":"https://www.wikidata.org/wiki/Q277521","display_name":"Relation (database)","level":2,"score":0.45132556557655334},{"id":"https://openalex.org/C2776533406","wikidata":"https://www.wikidata.org/wiki/Q187215","display_name":"Sympathetic nervous system","level":3,"score":0.4433459937572479},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.44313207268714905},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.441417396068573},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.4349466562271118},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4292307496070862},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2831501364707947},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.16340982913970947},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.13780611753463745},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13744735717773438},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.12287113070487976},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.10013830661773682},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.0},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:https://spectrum.library.concordia.ca:980481","doi":null,"is_oa":true,"landing_page_url":"https://spectrum.library.concordia.ca/980481/1/Rotenberg_PhD_F2015.pdf","pdf_url":"https://spectrum.library.concordia.ca/980481/1/Rotenberg_PhD_F2015.pdf","source":{"id":"https://openalex.org/S4306400871","display_name":"Spectrum Research Repository (Concordia University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I60158472","host_organization_name":"Concordia University","host_organization_lineage":["https://openalex.org/I60158472"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"mag:2208515426","doi":null,"is_oa":false,"landing_page_url":"https://spectrum.library.concordia.ca/980481/1/Rotenberg_PhD_F2015.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:https://spectrum.library.concordia.ca:980481","doi":null,"is_oa":true,"landing_page_url":"https://spectrum.library.concordia.ca/980481/1/Rotenberg_PhD_F2015.pdf","pdf_url":"https://spectrum.library.concordia.ca/980481/1/Rotenberg_PhD_F2015.pdf","source":{"id":"https://openalex.org/S4306400871","display_name":"Spectrum Research Repository (Concordia University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I60158472","host_organization_name":"Concordia University","host_organization_lineage":["https://openalex.org/I60158472"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2208515426.pdf","grobid_xml":"https://content.openalex.org/works/W2208515426.grobid-xml"},"referenced_works_count":221,"referenced_works":["https://openalex.org/W28296901","https://openalex.org/W62145855","https://openalex.org/W170233873","https://openalex.org/W321726205","https://openalex.org/W1264889757","https://openalex.org/W1491300853","https://openalex.org/W1531145115","https://openalex.org/W1555626073","https://openalex.org/W1566577700","https://openalex.org/W1570752686","https://openalex.org/W1577078797","https://openalex.org/W1577497395","https://openalex.org/W1604211023","https://openalex.org/W1610612296","https://openalex.org/W1682025172","https://openalex.org/W1739793538","https://openalex.org/W1849190772","https://openalex.org/W1917026153","https://openalex.org/W1955229004","https://openalex.org/W1963629744","https://openalex.org/W1963910089","https://openalex.org/W1964536565","https://openalex.org/W1965321175","https://openalex.org/W1965337411","https://openalex.org/W1965561480","https://openalex.org/W1966296687","https://openalex.org/W1966409424","https://openalex.org/W1966432951","https://openalex.org/W1967900132","https://openalex.org/W1968787277","https://openalex.org/W1970832453","https://openalex.org/W1971127409","https://openalex.org/W1971299923","https://openalex.org/W1971376356","https://openalex.org/W1971639265","https://openalex.org/W1973501977","https://openalex.org/W1973926831","https://openalex.org/W1974698688","https://openalex.org/W1976414968","https://openalex.org/W1976976596","https://openalex.org/W1977282282","https://openalex.org/W1977546485","https://openalex.org/W1980427432","https://openalex.org/W1980533762","https://openalex.org/W1983016072","https://openalex.org/W1983381709","https://openalex.org/W1983890872","https://openalex.org/W1984088895","https://openalex.org/W1985211733","https://openalex.org/W1987375729","https://openalex.org/W1987538872","https://openalex.org/W1987752641","https://openalex.org/W1988648434","https://openalex.org/W1989110716","https://openalex.org/W1991558113","https://openalex.org/W1991678398","https://openalex.org/W1991897097","https://openalex.org/W1994735233","https://openalex.org/W1996299251","https://openalex.org/W1997110253","https://openalex.org/W1998099581","https://openalex.org/W1998275162","https://openalex.org/W1998642320","https://openalex.org/W2006085701","https://openalex.org/W2006617357","https://openalex.org/W2007139321","https://openalex.org/W2007497220","https://openalex.org/W2007684928","https://openalex.org/W2008446010","https://openalex.org/W2009200163","https://openalex.org/W2009381080","https://openalex.org/W2012653434","https://openalex.org/W2013137850","https://openalex.org/W2014205754","https://openalex.org/W2014520341","https://openalex.org/W2017692334","https://openalex.org/W2020512725","https://openalex.org/W2022139094","https://openalex.org/W2022880000","https://openalex.org/W2027953236","https://openalex.org/W2028253727","https://openalex.org/W2028533410","https://openalex.org/W2028744383","https://openalex.org/W2028793343","https://openalex.org/W2028900007","https://openalex.org/W2030075252","https://openalex.org/W2032197162","https://openalex.org/W2033342135","https://openalex.org/W2034631176","https://openalex.org/W2034860511","https://openalex.org/W2034868207","https://openalex.org/W2035473397","https://openalex.org/W2035863630","https://openalex.org/W2036643530","https://openalex.org/W2037677597","https://openalex.org/W2038307448","https://openalex.org/W2038390253","https://openalex.org/W2040740684","https://openalex.org/W2040991357","https://openalex.org/W2041408564","https://openalex.org/W2041813688","https://openalex.org/W2042280485","https://openalex.org/W2044819977","https://openalex.org/W2046059023","https://openalex.org/W2046338576","https://openalex.org/W2046350184","https://openalex.org/W2046492532","https://openalex.org/W2046960533","https://openalex.org/W2049571889","https://openalex.org/W2053596632","https://openalex.org/W2054155432","https://openalex.org/W2056964135","https://openalex.org/W2057833102","https://openalex.org/W2057962659","https://openalex.org/W2058866099","https://openalex.org/W2062668919","https://openalex.org/W2064653350","https://openalex.org/W2066062828","https://openalex.org/W2067664488","https://openalex.org/W2068870243","https://openalex.org/W2069233820","https://openalex.org/W2069745518","https://openalex.org/W2070961645","https://openalex.org/W2071592631","https://openalex.org/W2072546823","https://openalex.org/W2073081893","https://openalex.org/W2073537354","https://openalex.org/W2073752934","https://openalex.org/W2074467897","https://openalex.org/W2075569196","https://openalex.org/W2076507733","https://openalex.org/W2077878019","https://openalex.org/W2077878361","https://openalex.org/W2078085538","https://openalex.org/W2078881833","https://openalex.org/W2079938187","https://openalex.org/W2083323397","https://openalex.org/W2084168249","https://openalex.org/W2085060024","https://openalex.org/W2086951593","https://openalex.org/W2089830108","https://openalex.org/W2093039467","https://openalex.org/W2093549515","https://openalex.org/W2094680561","https://openalex.org/W2097291981","https://openalex.org/W2097431774","https://openalex.org/W2097854556","https://openalex.org/W2098121774","https://openalex.org/W2100653236","https://openalex.org/W2102132607","https://openalex.org/W2105078707","https://openalex.org/W2105512321","https://openalex.org/W2107391440","https://openalex.org/W2108287509","https://openalex.org/W2108824181","https://openalex.org/W2109264166","https://openalex.org/W2109309002","https://openalex.org/W2110928922","https://openalex.org/W2111593351","https://openalex.org/W2113269449","https://openalex.org/W2114865973","https://openalex.org/W2116404316","https://openalex.org/W2117077354","https://openalex.org/W2117501598","https://openalex.org/W2120842367","https://openalex.org/W2122338287","https://openalex.org/W2122563474","https://openalex.org/W2123814189","https://openalex.org/W2125065795","https://openalex.org/W2125315255","https://openalex.org/W2127412413","https://openalex.org/W2129241490","https://openalex.org/W2132539548","https://openalex.org/W2133188156","https://openalex.org/W2133589238","https://openalex.org/W2133591735","https://openalex.org/W2134073711","https://openalex.org/W2134096679","https://openalex.org/W2135387276","https://openalex.org/W2136429434","https://openalex.org/W2138738783","https://openalex.org/W2141335918","https://openalex.org/W2142724666","https://openalex.org/W2143467061","https://openalex.org/W2144184072","https://openalex.org/W2144716474","https://openalex.org/W2145053954","https://openalex.org/W2145296402","https://openalex.org/W2145926418","https://openalex.org/W2149257689","https://openalex.org/W2149347145","https://openalex.org/W2149612743","https://openalex.org/W2151336952","https://openalex.org/W2151429049","https://openalex.org/W2154265360","https://openalex.org/W2154549730","https://openalex.org/W2156579478","https://openalex.org/W2157500613","https://openalex.org/W2158378430","https://openalex.org/W2160273439","https://openalex.org/W2160808328","https://openalex.org/W2161365979","https://openalex.org/W2162917240","https://openalex.org/W2163659027","https://openalex.org/W2163857054","https://openalex.org/W2164141618","https://openalex.org/W2165139442","https://openalex.org/W2166596324","https://openalex.org/W2166624057","https://openalex.org/W2167549446","https://openalex.org/W2167849338","https://openalex.org/W2168647804","https://openalex.org/W2168681940","https://openalex.org/W2168699761","https://openalex.org/W2169664690","https://openalex.org/W2171589158","https://openalex.org/W2305271344","https://openalex.org/W2315613231","https://openalex.org/W2412994771","https://openalex.org/W2797247465","https://openalex.org/W3021422392"],"related_works":["https://openalex.org/W2268919308","https://openalex.org/W4220680523","https://openalex.org/W4394673608","https://openalex.org/W2041911074","https://openalex.org/W6925272244","https://openalex.org/W4206256883","https://openalex.org/W4415301677","https://openalex.org/W4387747087","https://openalex.org/W7113546303","https://openalex.org/W2766343543"],"abstract_inverted_index":{"Stress,":[0],"via":[1],"the":[2,5,13,23,28,34,39,55,68,74,79,82,93,100,106,113,116,125,146,149,156,164,169,184,204,241,264,267,299,308,315,329,333],"activation":[3],"of":[4,15,20,38,54,95,105,115,148,198,208,233,314,335],"stress":[6,40,44,56,75,83,129,150,159,167,170,187,202,209,244,256,268,302,309,316,326],"response":[7,41,57,76,151,171,317],"system,":[8,42,152],"has":[9,319],"been":[10],"linked":[11],"to":[12,43,111,201,248,272,279,331],"emergence":[14,94],"cardiovascular":[16,46,96,134,192,212,249,273,304],"precursors.":[17],"The":[18,103,312],"majority":[19],"studies":[21,140,286,323],"relating":[22],"autonomic":[24],"nervous":[25,118],"system":[26,58,119,172,175,318],"and":[27,45,70,87,120,123,153,168,211,238,275,303],"hypothalamic":[29],"pituitary":[30],"adrenal":[31],"(HPA)":[32],"axis,":[33,122],"two":[35],"main":[36],"branches":[37],"precursors":[47,97,135,193,250],"have":[48],"focused":[49],"on":[50],"examining":[51,324],"each":[52],"branch":[53],"in":[59,99,194,230],"isolation.":[60],"However,":[61],"considering":[62,307],"only":[63],"these":[64,128,178,228,283],"singular":[65],"associations":[66],"disregards":[67],"structural":[69],"functional":[71],"inter-connection":[72],"between":[73,81,127,158,166,186,206,243,266,301],"systems.":[77],"Examining":[78],"inter-relation":[80,126,157,185,207,242,265,291],"systems":[84,130,160,188,210,245,269,310],"among":[85,136,218,251],"children":[86,219,234,253],"adolescents":[88],"is":[89],"particular":[90],"opportune":[91],"given":[92],"early":[98],"life":[101,223],"course.":[102],"objective":[104],"current":[107],"research":[108,260],"program":[109,261],"was":[110,131,189,215,246,270],"examine":[112],"patterning":[114,147,313],"cardio-autonomic":[117],"HPA":[121],"whether":[124],"associated":[132,190],"with":[133,191,220,254],"children.":[137,199],"\\n":[138],"Three":[139],"were":[141],"conducted.":[142],"Study":[143,180,225],"1":[144],"demonstrated":[145,182,239],"found":[154,262],"that":[155,183,240,263],"better":[161],"accounted":[162],"for":[163,236,321],"relation":[165],"than":[173,306],"either":[174],"alone.":[176],"Extending":[177],"results,":[179],"2":[181],"a":[195,231],"population-based":[196],"sample":[197,232],"Exposure":[200],"moderated":[203],"association":[205,300],"precursors,":[213,274],"which":[214,293],"more":[216],"robust":[217],"greater":[221,255,296],"stressful":[222,280],"events.":[224],"3":[226],"replicated":[227],"results":[229],"at-risk":[235,252],"obesity,":[237],"related":[247,271],"exposure.":[257],"\\nOverall,":[258],"this":[259],"children\u2019s":[276],"environmental":[277],"exposure":[278],"events":[281],"influenced":[282],"associations.":[284],"Future":[285],"should":[287],"consider":[288],"using":[289],"an":[290],"approach,":[292],"may":[294],"provide":[295],"insight":[297],"into":[298],"health":[305],"independently.":[311],"implications":[320],"future":[322],"how":[325],"\u201cgets":[327],"under":[328],"skin\u201d":[330],"promote":[332],"development":[334],"disease.":[336]},"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}
