{"id":"https://openalex.org/W2206287630","doi":null,"title":"Soluble cell adhesion molecules and parameters of lipoprotein metabolism in patients with severe burns.","display_name":"Soluble cell adhesion molecules and parameters of lipoprotein metabolism in patients with severe burns.","publication_year":2009,"publication_date":"2009-11-01","ids":{"openalex":"https://openalex.org/W2206287630","mag":"2206287630","pmid":"https://pubmed.ncbi.nlm.nih.gov/20441058"},"language":"en","primary_location":{"id":"pmid:20441058","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20441058","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The West Indian medical journal","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113650320","display_name":"F Rassoul","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210125843","display_name":"University Hospital Leipzig","ror":"https://ror.org/028hv5492","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210125843"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"F Rassoul","raw_affiliation_strings":["Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany. rassf@medizin.uni-leipzig.de"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Leipzig, Germany. rassf@medizin.uni-leipzig.de","institution_ids":["https://openalex.org/I4210125843"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066874948","display_name":"V Richter","orcid":"https://orcid.org/0000-0002-4723-1055","observed_orcids":["https://orcid.org/0000-0002-4723-1055"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V Richter","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"C Kistner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C Kistner","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009839298","display_name":"Dirk Wisser","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Wisser","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"B Reichert","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B Reichert","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3452,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.69251501,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"58","issue":"5","first_page":"417","last_page":"21"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11422","display_name":"Burn Injury Management and Outcomes","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11422","display_name":"Burn Injury Management and Outcomes","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14165","display_name":"Inflammation biomarkers and pathways","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/severe-burns","display_name":"severe burns","score":0.7689999938011169},{"id":"https://openalex.org/keywords/soluble-cell-adhesion-molecules","display_name":"soluble adhesion molecules","score":0.9309999942779541},{"id":"https://openalex.org/keywords/sicam-1","display_name":"sICAM-1","score":0.8579999804496765},{"id":"https://openalex.org/keywords/svcam-1","display_name":"sVCAM-1","score":0.9990000128746033},{"id":"https://openalex.org/keywords/soluble-e-selectin","display_name":"soluble E-selectin","score":0.9909999966621399},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.9100000262260437},{"id":"https://openalex.org/keywords/fibrinogen","display_name":"fibrinogen","score":1.0},{"id":"https://openalex.org/keywords/lipoprotein-metabolism","display_name":"lipoprotein metabolism","score":0.9739999771118164},{"id":"https://openalex.org/keywords/cholesterol","display_name":"cholesterol","score":0.5630000233650208},{"id":"https://openalex.org/keywords/triglycerides","display_name":"triglycerides","score":0.8510000109672546},{"id":"https://openalex.org/keywords/endothelial-activation","display_name":"endothelial activation","score":0.8899999856948853},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.7120000123977661},{"id":"https://openalex.org/keywords/burns","display_name":"burns","score":0.7820000052452087}],"concepts":[{"id":"https://openalex.org/C2779036427","wikidata":"https://www.wikidata.org/wiki/Q381899","display_name":"Fibrinogen","level":2,"score":0.7620964050292969},{"id":"https://openalex.org/C16224149","wikidata":"https://www.wikidata.org/wiki/Q187637","display_name":"Cell adhesion molecule","level":2,"score":0.7026828527450562},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6675242781639099},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.6481547355651855},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.6053295731544495},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5708335041999817},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.5411967039108276},{"id":"https://openalex.org/C132155493","wikidata":"https://www.wikidata.org/wiki/Q7558942","display_name":"Soluble cell adhesion molecules","level":4,"score":0.540111243724823},{"id":"https://openalex.org/C85789140","wikidata":"https://www.wikidata.org/wiki/Q187640","display_name":"Cell adhesion","level":3,"score":0.5155782103538513},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.5105100870132446},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.47252848744392395},{"id":"https://openalex.org/C4733338","wikidata":"https://www.wikidata.org/wiki/Q2792936","display_name":"Lipid metabolism","level":2,"score":0.4506511688232422},{"id":"https://openalex.org/C2780541478","wikidata":"https://www.wikidata.org/wiki/Q410020","display_name":"High-density lipoprotein","level":3,"score":0.4233730435371399},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4051188826560974},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.28632378578186035},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.254629909992218},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.2166532576084137}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002056","descriptor_name":"Burns","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D002097","descriptor_name":"C-Reactive Protein","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005340","descriptor_name":"Fibrinogen","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008074","descriptor_name":"Lipoproteins","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008076","descriptor_name":"Cholesterol, HDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008078","descriptor_name":"Cholesterol, LDL","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010865","descriptor_name":"Pilot Projects","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014280","descriptor_name":"Triglycerides","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015815","descriptor_name":"Cell Adhesion Molecules","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D018799","descriptor_name":"Intercellular Adhesion Molecule-1","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D019010","descriptor_name":"Vascular Cell Adhesion Molecule-1","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D019040","descriptor_name":"E-Selectin","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:20441058","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20441058","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The West Indian medical journal","raw_type":"Journal Article"},{"id":"mag:2206287630","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20441058","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1804556602","https://openalex.org/W1969582648","https://openalex.org/W1972840092","https://openalex.org/W1989200494","https://openalex.org/W1990025748","https://openalex.org/W2036909935","https://openalex.org/W2047334427","https://openalex.org/W2057699266","https://openalex.org/W2058030813","https://openalex.org/W2060521796","https://openalex.org/W2083175169","https://openalex.org/W2084852217","https://openalex.org/W2099422153","https://openalex.org/W2116404316","https://openalex.org/W2119427805","https://openalex.org/W2160841115","https://openalex.org/W2161470156","https://openalex.org/W2182743584","https://openalex.org/W2466944836"],"related_works":["https://openalex.org/W2099422153","https://openalex.org/W2362783502","https://openalex.org/W1994836351","https://openalex.org/W2364566055","https://openalex.org/W2043772494","https://openalex.org/W1154075862","https://openalex.org/W2401634930","https://openalex.org/W2263404729","https://openalex.org/W2413982528","https://openalex.org/W1971006680"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,59,169,211],"role":[2],"of":[3,17,38,46,62,100,106,111,141,160,205,215,237],"leukocyte":[4],"adhesion":[5,41,64,68,73,218],"molecules":[6,42,219],"in":[7,35,51,83,103,223,259],"patients":[8,52,85,238],"with":[9,53,86,148,177,194,239,264],"burns":[10,88,240],"and":[11,19,43,48,76,81,114,133,145,172,181,190],"their":[12],"relationship":[13],"to":[14,26,96,243,247],"other":[15,44],"parameters":[16,45],"inflammation":[18,47],"lipid":[20],"metabolism":[21,50],"is":[22],"only":[23],"recently":[24],"beginning":[25],"be":[27,221,257],"explored.":[28],"Therefore,":[29],"we":[30],"investigated":[31],"the":[32,36,98,104,179,182,245,252,261],"temporal":[33,253],"changes":[34,254],"levels":[37,61,110,140,159,174,207],"soluble":[39,63,216],"cell":[40,67,72,217],"lipoprotein":[49,124,129],"thermal":[54,154,167,200,229,265],"injury.":[55,155,168,201,230,266],"MATERIALS":[56],"AND":[57],"METHODS:":[58],"serum":[60,158],"molecules,":[65],"intercellular":[66],"molecule-1":[69,74],"(sICAM-1),":[70],"vascular":[71],"(sVCAM-1),":[75],"sE-selectin,":[77],"C-reactive":[78],"protein":[79],"(CRP)":[80],"fibrinogen":[82,146,183],"seven":[84],"severe":[87,107],"over":[89],"a":[90,234],"30-":[91],"day":[92],"period":[93],"were":[94,116,136,162],"measured":[95,249],"determine":[97],"involvement":[99],"these":[101],"factors":[102],"pathophysiology":[105],"burns.":[108],"Serum":[109],"slCAM-1,":[112],"sVCAM-1":[113,171],"sE-selectin":[115,161,173],"determined":[117],"by":[118],"ELISA.":[119],"Furthermore,":[120,202],"total":[121,186],"cholesterol,":[122,187],"high-density":[123],"cholesterol":[125,130,189,192],"(HDL":[126],"chol),":[127],"low-density":[128],"(LDL":[131],"chol)":[132],"triglycerides":[134],"(TG)":[135],"measured.":[137],"RESULTS:":[138],"Blood":[139],"sICAM-1,":[142,170],"sVCAM-1,":[143],"CRP":[144,180],"increased":[147],"maximum":[149],"values":[150,196],"six":[151],"days":[152,165,198],"after":[153,166,199],"In":[156],"contrast,":[157],"elevated":[163],"two":[164],"correlated":[175],"significantly":[176],"both":[178],"levels.":[184],"Plasma":[185],"HDL":[188],"LDL":[191],"decreased":[193],"minimum":[195],"four":[197],"an":[203],"increase":[204],"triglyceride":[206],"was":[208],"observed.":[209],"CONCLUSION:":[210],"observed":[212],"inflammatory":[213],"response":[214],"could":[220,256],"useful":[222],"monitoring":[224],"endothelial":[225],"activation":[226],"immediately":[227],"following":[228],"Further":[231],"studies":[232],"involving":[233],"larger":[235],"number":[236],"should":[241],"help":[242],"clarify":[244],"extent":[246],"which":[248],"parameters,":[250],"especially":[251],"ofsCAMs,":[255],"relevant":[258],"assessing":[260],"morbidity":[262],"ofpatients":[263]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}