{"id":"https://openalex.org/W2202033765","doi":null,"title":"Atypical Takayasu arteritis: a family with five affected siblings.","display_name":"Atypical Takayasu arteritis: a family with five affected siblings.","publication_year":2007,"publication_date":"2007-08-01","ids":{"openalex":"https://openalex.org/W2202033765","mag":"2202033765","pmid":"https://pubmed.ncbi.nlm.nih.gov/17660729"},"language":"en","primary_location":{"id":"pmid:17660729","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17660729","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical science monitor : international medical journal of experimental and clinical research","raw_type":"Case Reports"},"parent_works":[],"lineage":["https://openalex.org/W2202033765"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://ecommons.aku.edu/pakistan_fhs_mc_surg_ophthalmol/20","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035423204","display_name":"Irfan Kabiruddin Jeeva","orcid":"https://orcid.org/0000-0001-6786-0222","observed_orcids":["https://orcid.org/0000-0001-6786-0222"]},"institutions":[{"id":"https://openalex.org/I118185606","display_name":"Aga Khan University","ror":"https://ror.org/03gd0dm95","country_code":"PK","type":"education","lineage":["https://openalex.org/I118185606","https://openalex.org/I4210114929"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Irfan Jeeva","raw_affiliation_strings":["Department of Biological and Biomedical Sciences, Faculty of Health Sciences, Medical College, Faculty of Health Sciences, Aga Khan University, Karachi, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological and Biomedical Sciences, Faculty of Health Sciences, Medical College, Faculty of Health Sciences, Aga Khan University, Karachi, Pakistan","institution_ids":["https://openalex.org/I118185606"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044515109","display_name":"Jamal Sajid","orcid":"https://orcid.org/0000-0001-9318-4619","observed_orcids":["https://orcid.org/0000-0001-9318-4619"]},"institutions":[{"id":"https://openalex.org/I130828816","display_name":"University of Leeds","ror":"https://ror.org/024mrxd33","country_code":"GB","type":"education","lineage":["https://openalex.org/I130828816"]},{"id":"https://openalex.org/I2801331674","display_name":"St James's University Hospital","ror":"https://ror.org/013s89d74","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799390153","https://openalex.org/I2801331674"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jamal Sajid","raw_affiliation_strings":["Molecular Medicine Unit, University of Leeds, St. James\u2019s University Hospital, Leeds, U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Medicine Unit, University of Leeds, St. James\u2019s University Hospital, Leeds, U.K","institution_ids":["https://openalex.org/I130828816","https://openalex.org/I2801331674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017001334","display_name":"Ali Osman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I118185606","display_name":"Aga Khan University","ror":"https://ror.org/03gd0dm95","country_code":"PK","type":"education","lineage":["https://openalex.org/I118185606","https://openalex.org/I4210114929"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Osman Ali","raw_affiliation_strings":["Department of Biological and Biomedical Sciences, Faculty of Health Sciences, Medical College, Faculty of Health Sciences, Aga Khan University, Karachi, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological and Biomedical Sciences, Faculty of Health Sciences, Medical College, Faculty of Health Sciences, Aga Khan University, Karachi, Pakistan","institution_ids":["https://openalex.org/I118185606"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008230485","display_name":"David T. Bonthron","orcid":"https://orcid.org/0000-0001-8132-8179","observed_orcids":["https://orcid.org/0000-0001-8132-8179"]},"institutions":[{"id":"https://openalex.org/I130828816","display_name":"University of Leeds","ror":"https://ror.org/024mrxd33","country_code":"GB","type":"education","lineage":["https://openalex.org/I130828816"]},{"id":"https://openalex.org/I2801331674","display_name":"St James's University Hospital","ror":"https://ror.org/013s89d74","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2799390153","https://openalex.org/I2801331674"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David T Bonthron","raw_affiliation_strings":["Molecular Medicine Unit, University of Leeds, St. James\u2019s University Hospital, Leeds, U.K"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Medicine Unit, University of Leeds, St. James\u2019s University Hospital, Leeds, U.K","institution_ids":["https://openalex.org/I130828816","https://openalex.org/I2801331674"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103472297","display_name":"Philippe M. Frossard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I118185606","display_name":"Aga Khan University","ror":"https://ror.org/03gd0dm95","country_code":"PK","type":"education","lineage":["https://openalex.org/I118185606","https://openalex.org/I4210114929"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Philippe M Frossard","raw_affiliation_strings":["Department of Biological and Biomedical Sciences, Faculty of Health Sciences, Medical College, Faculty of Health Sciences, Aga Khan University, Karachi, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological and Biomedical Sciences, Faculty of Health Sciences, Medical College, Faculty of Health Sciences, Aga Khan University, Karachi, Pakistan","institution_ids":["https://openalex.org/I118185606"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4002,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.6443959,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"13","issue":"8","first_page":"CS101","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11194","display_name":"Ocular Diseases and Beh\u00e7et\u2019s Syndrome","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11892","display_name":"Kawasaki Disease and Coronary Complications","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/takayasu-arteritis","display_name":"Takayasu arteritis","score":0.9319999814033508},{"id":"https://openalex.org/keywords/giant-cell-arteritis","display_name":"giant cell arteritis","score":0.9660000205039978},{"id":"https://openalex.org/keywords/siblings","display_name":"siblings","score":0.4729999899864197},{"id":"https://openalex.org/keywords/pediatric-vasculitis","display_name":"pediatric vasculitis","score":0.6370000243186951},{"id":"https://openalex.org/keywords/aortic-involvement","display_name":"aortic involvement","score":0.6700000166893005},{"id":"https://openalex.org/keywords/vision-loss","display_name":"vision loss","score":0.4970000088214874},{"id":"https://openalex.org/keywords/retinal-changes","display_name":"retinal changes","score":0.6660000085830688},{"id":"https://openalex.org/keywords/renal-blood-flow","display_name":"renal blood flow","score":0.7020000219345093},{"id":"https://openalex.org/keywords/mitral-valve-prolapse","display_name":"mitral valve prolapse","score":0.9549999833106995},{"id":"https://openalex.org/keywords/autosomal-recessive-inheritance","display_name":"autosomal recessive inheritance","score":0.8190000057220459},{"id":"https://openalex.org/keywords/hla-association","display_name":"HLA association","score":0.7390000224113464},{"id":"https://openalex.org/keywords/magnetic-resonance-angiography","display_name":"magnetic resonance angiography","score":0.7680000066757202}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8058186769485474},{"id":"https://openalex.org/C2777910003","wikidata":"https://www.wikidata.org/wiki/Q1707292","display_name":"Asymptomatic","level":2,"score":0.6557873487472534},{"id":"https://openalex.org/C188997412","wikidata":"https://www.wikidata.org/wiki/Q1640386","display_name":"Proband","level":4,"score":0.6379672288894653},{"id":"https://openalex.org/C2781343717","wikidata":"https://www.wikidata.org/wiki/Q1751810","display_name":"Arteritis","level":2,"score":0.5295679569244385},{"id":"https://openalex.org/C2778212899","wikidata":"https://www.wikidata.org/wiki/Q907325","display_name":"Magnetic resonance angiography","level":3,"score":0.4996819496154785},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.47608819603919983},{"id":"https://openalex.org/C2781030672","wikidata":"https://www.wikidata.org/wiki/Q735652","display_name":"Mitral valve prolapse","level":3,"score":0.4729430675506592},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.470452219247818},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.40776678919792175},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.25490710139274597},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.1973746418952942},{"id":"https://openalex.org/C2777543888","wikidata":"https://www.wikidata.org/wiki/Q369939","display_name":"Mitral valve","level":2,"score":0.1341896653175354},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001766","descriptor_name":"Blindness","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005192","descriptor_name":"Family Health","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005808","descriptor_name":"Genes, Recessive","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006680","descriptor_name":"HLA Antigens","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D006680","descriptor_name":"HLA Antigens","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009422","descriptor_name":"Nervous System Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010154","descriptor_name":"Pakistan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010375","descriptor_name":"Pedigree","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013625","descriptor_name":"Takayasu Arteritis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D013625","descriptor_name":"Takayasu Arteritis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D013625","descriptor_name":"Takayasu Arteritis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D035781","descriptor_name":"Siblings","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"pmid:17660729","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17660729","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical science monitor : international medical journal of experimental and clinical research","raw_type":"Case Reports"},{"id":"pmh:oai:ecommons.aku.edu:pakistan_fhs_mc_bbs-2012","doi":null,"is_oa":false,"landing_page_url":"https://ecommons.aku.edu/pakistan_fhs_mc_bbs/1013","pdf_url":null,"source":{"id":"https://openalex.org/S4377196301","display_name":"eCommons - AKU (Aga Khan University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I118185606","host_organization_name":"Aga Khan University","host_organization_lineage":["https://openalex.org/I118185606"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Department of Biological & Biomedical Sciences","raw_type":"article"},{"id":"pmh:oai:ecommons.aku.edu:pakistan_fhs_mc_surg_ophthalmol-1019","doi":null,"is_oa":true,"landing_page_url":"https://ecommons.aku.edu/pakistan_fhs_mc_surg_ophthalmol/20","pdf_url":null,"source":{"id":"https://openalex.org/S4377196301","display_name":"eCommons - AKU (Aga Khan University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I118185606","host_organization_name":"Aga Khan University","host_organization_lineage":["https://openalex.org/I118185606"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Section of Ophthalmology","raw_type":"text"},{"id":"mag:2202033765","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17660729","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:ecommons.aku.edu:pakistan_fhs_mc_surg_ophthalmol-1019","doi":null,"is_oa":true,"landing_page_url":"https://ecommons.aku.edu/pakistan_fhs_mc_surg_ophthalmol/20","pdf_url":null,"source":{"id":"https://openalex.org/S4377196301","display_name":"eCommons - AKU (Aga Khan University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I118185606","host_organization_name":"Aga Khan University","host_organization_lineage":["https://openalex.org/I118185606"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Section of Ophthalmology","raw_type":"text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2150390014","https://openalex.org/W1988562875","https://openalex.org/W3037714306","https://openalex.org/W2164669615","https://openalex.org/W2404929108","https://openalex.org/W2057302144","https://openalex.org/W3198181781","https://openalex.org/W7166135995","https://openalex.org/W2130723322","https://openalex.org/W2413106134"],"abstract_inverted_index":{"BACKGROUND:":[0],"Takayasu":[1,67,100,190,210,229],"disease":[2,211,241],"is":[3,23,71,183],"a":[4,49,72],"giant":[5],"cell":[6],"arteritis,":[7,191],"primarily":[8],"affecting":[9],"the":[10,18,121,141,147,159,167,173,177,184,199,232,240],"aorta":[11,122,148],"and":[12,30,92,127,225,231],"its":[13],"main":[14],"branches,":[15],"particularly":[16],"over":[17],"first":[19,185],"1.5":[20],"cm.":[21],"It":[22],"more":[24,194],"common":[25],"in":[26,31,52,125,146,158,192,212,228],"South-East":[27],"Asian":[28],"countries":[29],"young":[32],"females,":[33],"whose":[34],"clinical":[35,224],"manifestations":[36],"range":[37],"from":[38],"asymptomatic":[39,170],"to":[40,60,86,154],"catastrophic":[41],"neurological":[42],"impairment.":[43],"CASE":[44],"REPORT:":[45],"We":[46],"report":[47],"on":[48],"Pakistani":[50],"family":[51,188],"which":[53,193],"five":[54],"of":[55,81,99,111,120,140,162,166,176,180,209,239],"seven":[56],"siblings,":[57],"aged":[58],"12":[59],"19":[61],"years,":[62],"are":[63,136,169],"affected":[64],"with":[65,77,189],"atypical":[66,118],"arteritis.":[68,101],"The":[69,143],"proband":[70,168],"14-year-old":[73],"male":[74],"who":[75],"presented":[76],"sudden,":[78],"painless":[79],"loss":[80],"vision.":[82],"He":[83],"was":[84],"found":[85],"have":[87],"absent":[88],"pulses,":[89],"retinal":[90],"changes":[91],"magnetic":[93],"resonance":[94],"angiography":[95],"(MRA)":[96],"findings":[97,135],"diagnostic":[98,174,200],"In":[102],"addition,":[103],"though,":[104],"he":[105],"had":[106],"decreased":[107,128],"intraocular":[108],"pressure,":[109],"murmur":[110],"mitral":[112],"valve":[113],"prolapse,":[114],"as":[115,117,123],"well":[116],"involvement":[119,145],"visualized":[124],"MRA":[126],"renal":[129],"blood":[130],"flow;":[131],"these":[132],"last":[133],"three":[134],"not":[137],"usual":[138],"features":[139],"disease.":[142],"unique":[144],"indicates":[149,218],"that":[150,220,234],"this":[151],"patient":[152],"corresponds":[153],"yet":[155],"another":[156],"sub-type":[157],"angiographic":[160],"classification":[161],"TA.":[163],"Four":[164],"siblings":[165],"but":[171],"fulfill":[172],"criteria":[175],"American":[178],"College":[179],"Rheumatology.":[181],"This":[182],"reported":[186],"multiplex":[187],"than":[195],"two":[196],"members":[197],"meet":[198],"criteria.":[201],"CONCLUSIONS:":[202],"Previous":[203],"reports":[204],"indicate":[205],"possible":[206],"HLA":[207],"associations":[208],"Japanese":[213],"patients.":[214],"Our":[215],"present":[216],"study":[217],"both":[219],"there":[221],"may":[222],"be":[223],"etiological":[226],"heterogeneity":[227],"disease,":[230],"possibility":[233],"an":[235],"autosomal":[236],"recessive":[237],"form":[238],"exists.":[242]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}