{"id":"https://openalex.org/W2201598970","doi":"https://doi.org/10.1093/carcin/bgv170","title":"Evaluation of potential regulatory function of breast cancer risk locus at 6q25.1","display_name":"Evaluation of potential regulatory function of breast cancer risk locus at 6q25.1","publication_year":2015,"publication_date":"2015-12-08","ids":{"openalex":"https://openalex.org/W2201598970","doi":"https://doi.org/10.1093/carcin/bgv170","mag":"2201598970","pmid":"https://pubmed.ncbi.nlm.nih.gov/26645718","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5006208"},"language":"en","primary_location":{"id":"doi:10.1093/carcin/bgv170","doi":"https://doi.org/10.1093/carcin/bgv170","is_oa":true,"landing_page_url":"https://doi.org/10.1093/carcin/bgv170","pdf_url":"https://academic.oup.com/carcin/article-pdf/37/2/163/17294416/bgv170.pdf","source":{"id":"https://openalex.org/S184620562","display_name":"Carcinogenesis","issn_l":"0143-3334","issn":["0143-3334","1460-2180"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Carcinogenesis","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/carcin/article-pdf/37/2/163/17294416/bgv170.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062525385","display_name":"Yaqiong Sun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4210161402","display_name":"Shanghai Municipal Center For Disease Control Prevention","ror":"https://ror.org/04w00xm72","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210161402","https://openalex.org/I4210165456"]},{"id":"https://openalex.org/I4390039299","display_name":"Vanderbilt-Ingram Cancer Center","ror":"https://ror.org/02rjj2m04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I4390039299","https://openalex.org/I901861585"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Yaqiong Sun","raw_affiliation_strings":["Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA","Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I4390039299"]},{"raw_affiliation_string":"Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China and","institution_ids":["https://openalex.org/I4210161402"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012748035","display_name":"Chuanzhong Ye","orcid":"https://orcid.org/0000-0002-3584-1075","observed_orcids":["https://orcid.org/0000-0002-3584-1075"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4390039299","display_name":"Vanderbilt-Ingram Cancer Center","ror":"https://ror.org/02rjj2m04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I4390039299","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chuanzhong Ye","raw_affiliation_strings":["Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA,","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I4390039299"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086299976","display_name":"Xingyi Guo","orcid":"https://orcid.org/0000-0001-5269-1294","observed_orcids":["https://orcid.org/0000-0001-5269-1294"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4390039299","display_name":"Vanderbilt-Ingram Cancer Center","ror":"https://ror.org/02rjj2m04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I4390039299","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xingyi Guo","raw_affiliation_strings":["Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA,","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I4390039299"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086118402","display_name":"Wanqing Wen","orcid":"https://orcid.org/0000-0002-3004-5168","observed_orcids":["https://orcid.org/0000-0002-3004-5168"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4390039299","display_name":"Vanderbilt-Ingram Cancer Center","ror":"https://ror.org/02rjj2m04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I4390039299","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wanqing Wen","raw_affiliation_strings":["Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA,","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I4390039299"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101592761","display_name":"Jirong Long","orcid":"https://orcid.org/0000-0002-7433-9766","observed_orcids":["https://orcid.org/0000-0002-7433-9766"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4390039299","display_name":"Vanderbilt-Ingram Cancer Center","ror":"https://ror.org/02rjj2m04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I4390039299","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jirong Long","raw_affiliation_strings":["Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA,","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I4390039299"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080361653","display_name":"Yu\u2010Tang Gao","orcid":"https://orcid.org/0000-0003-3904-1777","observed_orcids":["https://orcid.org/0000-0003-3904-1777"]},"institutions":[{"id":"https://openalex.org/I4210110011","display_name":"Shanghai Cancer Institute","ror":"https://ror.org/01ty4bg86","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210110011"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yu-Tang Gao","raw_affiliation_strings":["Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China","institution_ids":["https://openalex.org/I4210110011"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045077450","display_name":"Xiao Ou Shu","orcid":"https://orcid.org/0000-0002-1053-1353","observed_orcids":["https://orcid.org/0000-0002-1053-1353"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4390039299","display_name":"Vanderbilt-Ingram Cancer Center","ror":"https://ror.org/02rjj2m04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I4390039299","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiao Ou Shu","raw_affiliation_strings":["Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA,","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I4390039299"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100401143","display_name":"Wei Zheng","orcid":"https://orcid.org/0000-0003-1226-070X","observed_orcids":["https://orcid.org/0000-0003-1226-070X","https://orcid.org/0000-0003-1034-0757","https://orcid.org/0009-0008-5993-0647"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4390039299","display_name":"Vanderbilt-Ingram Cancer Center","ror":"https://ror.org/02rjj2m04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I4390039299","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wei Zheng","raw_affiliation_strings":["Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA,","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I4390039299"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005513706","display_name":"Qiuyin Cai","orcid":"https://orcid.org/0000-0002-9384-5648","observed_orcids":["https://orcid.org/0000-0002-9384-5648"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4390039299","display_name":"Vanderbilt-Ingram Cancer Center","ror":"https://ror.org/02rjj2m04","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I4390039299","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Qiuyin Cai","raw_affiliation_strings":["Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, 37203, USA,","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I4390039299"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5005513706"],"corresponding_institution_ids":["https://openalex.org/I200719446","https://openalex.org/I4390039299"],"apc_list":{"value":4835,"currency":"USD","value_usd":4835},"apc_paid":null,"fwci":1.6543,"has_fulltext":true,"cited_by_count":22,"citation_normalized_percentile":{"value":0.84154706,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"37","issue":"2","first_page":"163","last_page":"168"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":0.007199999876320362,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.0031999999191612005,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.9340000152587891},{"id":"https://openalex.org/keywords/akap12","display_name":"AKAP12","score":0.875},{"id":"https://openalex.org/keywords/esr1","display_name":"ESR1","score":1.0},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.7870000004768372},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.8830000162124634},{"id":"https://openalex.org/keywords/linkage-disequilibrium","display_name":"linkage disequilibrium","score":0.7570000290870667},{"id":"https://openalex.org/keywords/chinese-women","display_name":"Chinese women","score":0.5659999847412109},{"id":"https://openalex.org/keywords/tumor-versus-normal-tissue-expression","display_name":"tumor versus normal tissue expression","score":0.5460000038146973}],"concepts":[{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.8099209070205688},{"id":"https://openalex.org/C84597430","wikidata":"https://www.wikidata.org/wiki/Q106227","display_name":"Locus (genetics)","level":3,"score":0.7867016792297363},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.7865349054336548},{"id":"https://openalex.org/C139275648","wikidata":"https://www.wikidata.org/wiki/Q17134011","display_name":"SNP","level":5,"score":0.6803992986679077},{"id":"https://openalex.org/C35605836","wikidata":"https://www.wikidata.org/wiki/Q2064311","display_name":"Linkage disequilibrium","level":5,"score":0.6354809403419495},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5836900472640991},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.5765354633331299},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5342098474502563},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.5232828259468079},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.50332111120224},{"id":"https://openalex.org/C186413461","wikidata":"https://www.wikidata.org/wiki/Q744727","display_name":"Genetic association","level":5,"score":0.44925224781036377},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.34143948554992676},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.32152658700942993},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23856490850448608}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002896","descriptor_name":"Chromosomes, Human, Pair 6","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015810","descriptor_name":"Linkage Disequilibrium","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018797","descriptor_name":"Cell Cycle Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D020641","descriptor_name":"Polymorphism, Single Nucleotide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D044466","descriptor_name":"Asian People","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D054758","descriptor_name":"A Kinase Anchor Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D055106","descriptor_name":"Genome-Wide Association Study","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1093/carcin/bgv170","doi":"https://doi.org/10.1093/carcin/bgv170","is_oa":true,"landing_page_url":"https://doi.org/10.1093/carcin/bgv170","pdf_url":"https://academic.oup.com/carcin/article-pdf/37/2/163/17294416/bgv170.pdf","source":{"id":"https://openalex.org/S184620562","display_name":"Carcinogenesis","issn_l":"0143-3334","issn":["0143-3334","1460-2180"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Carcinogenesis","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5006208","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5006208","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Carcinogenesis","raw_type":"Text"},{"id":"pmid:26645718","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26645718","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Carcinogenesis","raw_type":"Journal Article"},{"id":"pmh:oai:open-archive.highwire.org:carcin:37/2/163","doi":null,"is_oa":false,"landing_page_url":"http://carcin.oxfordjournals.org/cgi/content/short/37/2/163","pdf_url":null,"source":{"id":"https://openalex.org/S4406923041","display_name":"HighWire Press Open Archive","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"TEXT"}],"best_oa_location":{"id":"doi:10.1093/carcin/bgv170","doi":"https://doi.org/10.1093/carcin/bgv170","is_oa":true,"landing_page_url":"https://doi.org/10.1093/carcin/bgv170","pdf_url":"https://academic.oup.com/carcin/article-pdf/37/2/163/17294416/bgv170.pdf","source":{"id":"https://openalex.org/S184620562","display_name":"Carcinogenesis","issn_l":"0143-3334","issn":["0143-3334","1460-2180"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Carcinogenesis","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9907000064849854,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G1114082741","display_name":"Vanderbilt-Shanghai Chronic Disease Research Training Program","funder_award_id":"D43TW008313","funder_id":"https://openalex.org/F4320337356","funder_display_name":"Fogarty International Center"},{"id":"https://openalex.org/G1520898414","display_name":"Shanghai Breast Cancer Study","funder_award_id":"R01CA064277","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G2763861","display_name":"Cell Cycle/Apoptosis Gene Variants and Breast Cancer Risk","funder_award_id":"R01CA122756","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G3236030556","display_name":"Consortium Study to Identify Breast Cancer Susceptibility Loci","funder_award_id":"R01CA148667","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G3269002440","display_name":null,"funder_award_id":"P30 CA068485","funder_id":"https://openalex.org/F4320309601","funder_display_name":"Vanderbilt-Ingram Cancer Center"},{"id":"https://openalex.org/G3717058984","display_name":"Molecular Epidemiologic Study of Breast Cancer","funder_award_id":"R01CA090899","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000880732","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA068485","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320309151","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34"},{"id":"https://openalex.org/F4320309601","display_name":"Vanderbilt-Ingram Cancer Center","ror":"https://ror.org/05dq2gs74"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337356","display_name":"Fogarty International Center","ror":"https://ror.org/02xey9a22"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2201598970.pdf","grobid_xml":"https://content.openalex.org/works/W2201598970.grobid-xml"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W151919668","https://openalex.org/W1972578281","https://openalex.org/W1988403972","https://openalex.org/W1994911859","https://openalex.org/W1999016712","https://openalex.org/W2001701937","https://openalex.org/W2008651555","https://openalex.org/W2009703738","https://openalex.org/W2025962794","https://openalex.org/W2038228368","https://openalex.org/W2057268591","https://openalex.org/W2057994246","https://openalex.org/W2061096783","https://openalex.org/W2067272783","https://openalex.org/W2067975491","https://openalex.org/W2088524199","https://openalex.org/W2097901251","https://openalex.org/W2103707052","https://openalex.org/W2111890489","https://openalex.org/W2113328185","https://openalex.org/W2122698311","https://openalex.org/W2123411711","https://openalex.org/W2135665336","https://openalex.org/W2137353408","https://openalex.org/W2141820415","https://openalex.org/W2142329875","https://openalex.org/W2144151059","https://openalex.org/W2151787127","https://openalex.org/W2153981365","https://openalex.org/W2159876044","https://openalex.org/W2164547119","https://openalex.org/W2167144418","https://openalex.org/W2168230468","https://openalex.org/W2168568597","https://openalex.org/W2184996901","https://openalex.org/W4232254206","https://openalex.org/W6686160282"],"related_works":["https://openalex.org/W2113328185","https://openalex.org/W2004620524","https://openalex.org/W1991608470","https://openalex.org/W2019537886","https://openalex.org/W2001701937","https://openalex.org/W3211035402","https://openalex.org/W7028718578","https://openalex.org/W1964251403","https://openalex.org/W2009703738","https://openalex.org/W2156244763"],"abstract_inverted_index":{"In":[0,135],"a":[1,25,68,151,161,191],"genome-wide":[2],"association":[3,71,209],"study":[4,205],"conducted":[5],"among":[6],"Chinese":[7],"women,":[8],"we":[9,33],"identified":[10],"the":[11,41,58,73,77,90,114,141,157,165,196,208,211,227],"single":[12],"nucleotide":[13],"polymorphism":[14],"(SNP)":[15],"rs2046210":[16,66,125,147],"at":[17,40],"6q25.1":[18,212],"for":[19,29,113],"breast":[20,44,85,215],"cancer":[21,45,216],"risk.":[22],"To":[23],"explore":[24],"potential":[26,192],"regulatory":[27],"role":[28],"this":[30],"risk":[31,92,143,217],"locus,":[32],"measured":[34],"expression":[35,74,128,154],"levels":[36,75,129],"of":[37,76,97,123,145,156,164,226],"nine":[38],"genes":[39,81,100],"locus":[42,213],"in":[43,57,82,132,168,182],"tissue":[46,50],"and":[47,79,111,116,160,214],"adjacent":[48,83],"normal":[49,84],"samples":[51],"obtained":[52],"from":[53,203],"67":[54],"patients":[55],"recruited":[56],"Shanghai":[59],"Breast":[60],"Cancer":[61,137],"Study.":[62],"We":[63],"found":[64,131],"that":[65,177,207,223],"had":[67,94],"statistically":[69],"significant":[70,121],"with":[72,126,150,186],"AKAP12":[78,115,158,197,228],"ESR1":[80,166],"tissues.":[86,134],"Women":[87],"who":[88,104],"carry":[89,105],"AA/AG":[91,142],"genotypes":[93,107,144],"higher":[95,153],"expressions":[96,225],"these":[98,201],"two":[99],"compared":[101],"to":[102],"those":[103],"G/G":[106],"(P":[108],"=":[109],"0.02":[110],"0.04":[112],"ESR1,":[117],"respectively).":[118],"However,":[119],"no":[120],"differences":[122],"SNP":[124,146,178,187],"gene":[127,159,167],"were":[130,148],"tumor":[133,169],"The":[136],"Genome":[138],"Atlas":[139],"samples,":[140],"associated":[149],"significantly":[152],"level":[155,163],"lower":[162],"tissue.":[170],"Functional":[171],"analysis":[172],"using":[173],"ENCODE":[174],"data":[175],"revealed":[176],"rs7763637,":[179],"which":[180],"is":[181,189],"strong":[183],"linkage":[184],"disequilibrium":[185],"rs2046210,":[188],"likely":[190],"functional":[193],"variant,":[194],"regulating":[195],"gene.":[198,229],"Taken":[199],"together,":[200],"results":[202],"our":[204],"suggest":[206],"between":[210],"may":[218],"be":[219],"mediated":[220],"through":[221],"SNPs":[222],"regulate":[224]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
