{"id":"https://openalex.org/W2201539629","doi":"https://doi.org/10.1161/circ.130.suppl_2.271","title":"Abstract 271: Continuous Amplitude Spectral Area May Reflect Adequacy of Myocardial Perfusion Before Attempting Defibrillation","display_name":"Abstract 271: Continuous Amplitude Spectral Area May Reflect Adequacy of Myocardial Perfusion Before Attempting Defibrillation","publication_year":2014,"publication_date":"2014-11-25","ids":{"openalex":"https://openalex.org/W2201539629","doi":"https://doi.org/10.1161/circ.130.suppl_2.271","mag":"2201539629"},"language":"en","primary_location":{"id":"doi:10.1161/circ.130.suppl_2.271","doi":"https://doi.org/10.1161/circ.130.suppl_2.271","is_oa":false,"landing_page_url":"https://doi.org/10.1161/circ.130.suppl_2.271","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014186524","display_name":"Ra\u00fal J. Gazmuri","orcid":"https://orcid.org/0000-0002-3848-7227","observed_orcids":["https://orcid.org/0000-0002-3848-7227"]},"institutions":[{"id":"https://openalex.org/I189273616","display_name":"Rosalind Franklin University of Medicine and Science","ror":"https://ror.org/04fegvg32","country_code":"US","type":"education","lineage":["https://openalex.org/I189273616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ra\u00fal J Gazmuri","raw_affiliation_strings":["Medicine, Rosalind Franklin Univ of Medicine and Science, North Chicago, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medicine, Rosalind Franklin Univ of Medicine and Science, North Chicago, IL","institution_ids":["https://openalex.org/I189273616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111780669","display_name":"Christopher L. Kaufman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4392738065","display_name":"ZOLL Medical Corporation (United States)","ror":"https://ror.org/036wkjd70","country_code":"US","type":"company","lineage":["https://openalex.org/I4210102907","https://openalex.org/I4392738065"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher L Kaufman","raw_affiliation_strings":["ZOLL Med Corp, Chelmsford, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ZOLL Med Corp, Chelmsford, MA","institution_ids":["https://openalex.org/I4392738065"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008101045","display_name":"Herbert K Whitehouse","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189273616","display_name":"Rosalind Franklin University of Medicine and Science","ror":"https://ror.org/04fegvg32","country_code":"US","type":"education","lineage":["https://openalex.org/I189273616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Herbert K Whitehouse","raw_affiliation_strings":["Rosalind Franklin Univ of Medicine and Science, North Chicago, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rosalind Franklin Univ of Medicine and Science, North Chicago, IL","institution_ids":["https://openalex.org/I189273616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054402310","display_name":"Alvin Baetiong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189273616","display_name":"Rosalind Franklin University of Medicine and Science","ror":"https://ror.org/04fegvg32","country_code":"US","type":"education","lineage":["https://openalex.org/I189273616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alvin Baetiong","raw_affiliation_strings":["Rosalind Franklin Univ of Medicine and Science, North Chicago, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rosalind Franklin Univ of Medicine and Science, North Chicago, IL","institution_ids":["https://openalex.org/I189273616"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113764706","display_name":"Jeejabai Radhakrishnan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189273616","display_name":"Rosalind Franklin University of Medicine and Science","ror":"https://ror.org/04fegvg32","country_code":"US","type":"education","lineage":["https://openalex.org/I189273616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeejabai Radhakrishnan","raw_affiliation_strings":["Rosalind Franklin Univ of Medicine and Science, North Chicago, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rosalind Franklin Univ of Medicine and Science, North Chicago, IL","institution_ids":["https://openalex.org/I189273616"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"130","issue":"suppl_2","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10645","display_name":"Cardiac Arrest and Resuscitation","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10645","display_name":"Cardiac Arrest and Resuscitation","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10675","display_name":"Mechanical Circulatory Support Devices","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ventricular-fibrillation","display_name":"ventricular fibrillation","score":0.9240000247955322},{"id":"https://openalex.org/keywords/defibrillation","display_name":"defibrillation","score":0.796999990940094},{"id":"https://openalex.org/keywords/myocardial-perfusion","display_name":"myocardial perfusion","score":0.8429999947547913},{"id":"https://openalex.org/keywords/coronary-perfusion-pressure","display_name":"coronary perfusion pressure","score":0.8450000286102295},{"id":"https://openalex.org/keywords/extracorporeal-circulation","display_name":"extracorporeal circulation","score":0.9710000157356262},{"id":"https://openalex.org/keywords/cardiopulmonary-resuscitation","display_name":"cardiopulmonary resuscitation","score":0.9089999794960022},{"id":"https://openalex.org/keywords/electric-shock","display_name":"electric shock","score":0.5889999866485596},{"id":"https://openalex.org/keywords/pig-model","display_name":"porcine model","score":0.7910000085830688},{"id":"https://openalex.org/keywords/return-of-spontaneous-circulation","display_name":"return of spontaneous circulation","score":0.8360000252723694}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9050508737564087},{"id":"https://openalex.org/C146957229","wikidata":"https://www.wikidata.org/wiki/Q1266915","display_name":"Perfusion","level":2,"score":0.682533860206604},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.646507740020752},{"id":"https://openalex.org/C2781300812","wikidata":"https://www.wikidata.org/wiki/Q178061","display_name":"Shock (circulatory)","level":2,"score":0.5975282788276672},{"id":"https://openalex.org/C2777795826","wikidata":"https://www.wikidata.org/wiki/Q954202","display_name":"Defibrillation","level":2,"score":0.5762220025062561},{"id":"https://openalex.org/C2776157398","wikidata":"https://www.wikidata.org/wiki/Q497232","display_name":"Coronary circulation","level":3,"score":0.5369778275489807},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5296573042869568},{"id":"https://openalex.org/C2994232697","wikidata":"https://www.wikidata.org/wiki/Q1115882","display_name":"Extracorporeal circulation","level":2,"score":0.4567053020000458},{"id":"https://openalex.org/C2777862461","wikidata":"https://www.wikidata.org/wiki/Q5172193","display_name":"Coronary perfusion pressure","level":4,"score":0.4460931420326233},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.44511353969573975},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.35920238494873047},{"id":"https://openalex.org/C2777055891","wikidata":"https://www.wikidata.org/wiki/Q185325","display_name":"Cardiopulmonary resuscitation","level":3,"score":0.3038925528526306},{"id":"https://openalex.org/C2778165595","wikidata":"https://www.wikidata.org/wiki/Q5491454","display_name":"Resuscitation","level":2,"score":0.17212021350860596}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1161/circ.130.suppl_2.271","doi":"https://doi.org/10.1161/circ.130.suppl_2.271","is_oa":false,"landing_page_url":"https://doi.org/10.1161/circ.130.suppl_2.271","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Circulation","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9476000070571899}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7699999809265137}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2901307720","https://openalex.org/W2518575026","https://openalex.org/W4404344090","https://openalex.org/W2760424230","https://openalex.org/W4200197778","https://openalex.org/W2901670068","https://openalex.org/W2210306273","https://openalex.org/W2408961690","https://openalex.org/W2889920494","https://openalex.org/W2766037853"],"abstract_inverted_index":{"Background:":[0],"Previous":[1],"studies":[2],"have":[3],"shown":[4],"that":[5,24,162,236,262,286],"analysis":[6],"of":[7,16,35,59,96,103,120,185,212,275,289],"the":[8,21,87,107,136,181,210,224,273,279,287,299,303],"VF":[9,36,63,199],"amplitude-spectral":[10],"area":[11],"(AMSA)":[12],"contains":[13],"information":[14],"predictive":[15],"electrical":[17,127,276],"shock":[18,194],"success.":[19],"However,":[20],"underlying":[22],"factors":[23],"determine":[25],"AMSA":[26,54,149,178,227,243,261,290],"remain":[27],"elusive.":[28],"We":[29],"developed":[30],"an":[31,104],"open-chest":[32],"swine":[33],"model":[34],"in":[37,55,73,202,209,215,260],"which":[38,77,206,302],"we":[39],"modeled":[40],"\u201caverage":[41],"CPR\u201d":[42,47],"followed":[43],"by":[44,269,298],"\u201chighly":[45],"effective":[46],"using":[48],"extracorporeal":[49],"circulation":[50,214],"(ECC)":[51],"and":[52,67,81,112,158,168,266,272],"assessed":[53],"relation":[56],"to":[57,89,114,145,197,204,220,292],"adequacy":[58],"coronary":[60,92,307],"perfusion.":[61],"Methods:":[62],"was":[64,79,110,142,150,169,244],"electrically":[65],"induced":[66],"left":[68,137],"untreated":[69],"for":[70,83,173,234],"8":[71,74],"min":[72,85,172,184],"pigs":[75],"after":[76,218],"ECC":[78,108,203],"started":[80],"maintained":[82],"10":[84,97],"adjusting":[86],"flow":[88,109,134],"generate":[90],"a":[91,116,154,159],"perfusion":[93,271],"pressure":[94,119],"(CPP)":[95],"mmHg":[98,122],"(low-flow":[99],"ECC).":[100],"After":[101],"delivery":[102],"initial":[105,182,193],"shock,":[106],"increased":[111,179,229],"titrated":[113],"secure":[115],"mean":[117],"aortic":[118],"40":[121],"(high-flow":[123],"ECC)":[124],"delivering":[125],"additional":[126],"shocks":[128,277],"at":[129],"60":[130],"s":[131,156],"intervals.":[132],"Blood":[133],"through":[135],"anterior":[138],"descending":[139],"(LAD)":[140],"artery":[141],"reported":[143],"relative":[144],"baseline":[146],"(LAD":[147],"rel).":[148],"measured":[151],"continuously":[152],"with":[153,247,301],"2.1":[155],"timeframe":[157],"Tukey":[160],"window":[161],"moved":[163],"ahead":[164],"every":[165,171],"0.5":[166],"s,":[167],"averaged":[170],"this":[174],"report":[175],"(Figure).":[176,191],"Results:":[177],"during":[180],"5":[183,221],"low-flow":[186],"ECC,":[187,226],"but":[188,230],"subsequently":[189],"decreased":[190,233],"The":[192,253,281],"uniformly":[195],"failed":[196],"terminate":[198],"prompting":[200],"increases":[201],"high-flow,":[205],"then":[207,231],"resulted":[208],"return":[211],"spontaneous":[213],"each":[216],"instance":[217],"3":[219],"shocks.":[222],"During":[223],"high-flow":[225],"initially":[228],"gradually":[232],"reasons":[235],"are":[237,263],"not":[238],"clear.":[239],"Before":[240],"attempting":[241,293],"defibrillation,":[242],"positively":[245],"correlated":[246],"LAD":[248],"rel":[249],"(r=0.73,":[250],"p=0.04).":[251],"Conclusion:":[252],"study":[254,283],"provides":[255],"intriguing":[256],"data":[257],"showing":[258],"changes":[259],"time":[264],"dependent":[265],"likely":[267],"influenced":[268,297],"myocardial":[270],"effects":[274],"on":[278],"myocardium.":[280],"present":[282],"also":[284],"suggests":[285],"level":[288],"prior":[291],"defibrillation":[294],"may":[295],"be":[296],"efficacy":[300],"CPR":[304],"intervention":[305],"generates":[306],"blood":[308],"flow.":[309]},"counts_by_year":[],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2016-06-24T00:00:00"}