{"id":"https://openalex.org/W2200777547","doi":null,"title":"Propranolol and D-cycloserine as adjunctive medications in reducing dental fear in sedation practice.","display_name":"Propranolol and D-cycloserine as adjunctive medications in reducing dental fear in sedation practice.","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W2200777547","mag":"2200777547","pmid":"https://pubmed.ncbi.nlm.nih.gov/20151608","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2893885"},"language":"en","primary_location":{"id":"pmid:20151608","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20151608","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SAAD digest","raw_type":"Journal Article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2893885/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013410879","display_name":"Lisa J. Heaton","orcid":"https://orcid.org/0000-0003-2670-7402","observed_orcids":["https://orcid.org/0000-0003-2670-7402"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lisa J Heaton","raw_affiliation_strings":["Dental Fears Research Clinic, Department of Dental Public Health Sciences, Box 357475, University of Washington, Seattle, WA 98195-7475, USA. lheaton@u.washington.edu","Dental Fears Research Clinic, Department of Dental Public Health Sciences, Box 357475, University of Washington, Seattle, WA 98195-7475, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dental Fears Research Clinic, Department of Dental Public Health Sciences, Box 357475, University of Washington, Seattle, WA 98195-7475, USA. lheaton@u.washington.edu","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Dental Fears Research Clinic, Department of Dental Public Health Sciences, Box 357475, University of Washington, Seattle, WA 98195-7475, USA","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059822764","display_name":"Daniel W. McNeil","orcid":"https://orcid.org/0000-0002-0766-8455","observed_orcids":["https://orcid.org/0000-0002-0766-8455"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel W McNeil","raw_affiliation_strings":["University of Washington ;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Washington ;","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006178504","display_name":"Peter Milgrom","orcid":"https://orcid.org/0000-0003-0784-9181","observed_orcids":["https://orcid.org/0000-0003-0784-9181"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter Milgrom","raw_affiliation_strings":["University of Washington ;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Washington ;","institution_ids":["https://openalex.org/I201448701"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I201448701"],"apc_list":null,"apc_paid":null,"fwci":0.3738,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.28205128,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"26","issue":null,"first_page":"27","last_page":"35"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12145","display_name":"Dental Anxiety and Anesthesia Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12145","display_name":"Dental Anxiety and Anesthesia Techniques","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3504","display_name":"Oral Surgery"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10436","display_name":"Anesthesia and Sedative Agents","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/propranolol","display_name":"propranolol","score":0.9610000252723694},{"id":"https://openalex.org/keywords/d-cycloserine","display_name":"D-cycloserine","score":1.0},{"id":"https://openalex.org/keywords/dental-anxiety","display_name":"dental anxiety","score":0.9039999842643738},{"id":"https://openalex.org/keywords/sedation","display_name":"sedation","score":0.531000018119812},{"id":"https://openalex.org/keywords/adjunctive-pharmacotherapy","display_name":"adjunctive pharmacotherapy","score":0.8939999938011169},{"id":"https://openalex.org/keywords/dental-treatment","display_name":"dental treatment","score":0.43299999833106995}],"concepts":[{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.7134377956390381},{"id":"https://openalex.org/C2776814716","wikidata":"https://www.wikidata.org/wiki/Q574801","display_name":"Sedation","level":2,"score":0.65510094165802},{"id":"https://openalex.org/C2778151854","wikidata":"https://www.wikidata.org/wiki/Q423364","display_name":"Propranolol","level":2,"score":0.4837034344673157},{"id":"https://openalex.org/C2991918945","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dental practice","level":2,"score":0.4645084738731384},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4636586308479309},{"id":"https://openalex.org/C2776693998","wikidata":"https://www.wikidata.org/wiki/Q5259410","display_name":"Dental care","level":2,"score":0.4280022382736206},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.42309531569480896},{"id":"https://openalex.org/C202269582","wikidata":"https://www.wikidata.org/wiki/Q2644277","display_name":"Complementarity (molecular biology)","level":2,"score":0.41372811794281006},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.37196213006973267},{"id":"https://openalex.org/C542102704","wikidata":"https://www.wikidata.org/wiki/Q183257","display_name":"Psychotherapist","level":1,"score":0.33460158109664917},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.27816179394721985},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.1917077600955963},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000223","descriptor_name":"Adaptation, Psychological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000759","descriptor_name":"Adjuvants, Anesthesia","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000766","descriptor_name":"Anesthesia, Dental","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001521","descriptor_name":"Behavior Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003523","descriptor_name":"Cycloserine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011433","descriptor_name":"Propranolol","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D014151","descriptor_name":"Anti-Anxiety Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D016292","descriptor_name":"Procedural Sedation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016854","descriptor_name":"Dental Anxiety","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true}],"locations_count":3,"locations":[{"id":"pmid:20151608","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20151608","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"SAAD digest","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:2893885","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2893885/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"SAAD Dig","raw_type":"Text"},{"id":"mag:2200777547","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20151608","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2893885","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2893885/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"SAAD Dig","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2613247470","display_name":"Addressing Oral Health Disparities in Individuals with Mental Health Problems","funder_award_id":"K23DE019202","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"},{"id":"https://openalex.org/G4403401385","display_name":"Factors Contributing to Oral Health Disparities in Appalachia","funder_award_id":"R01DE014899","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"}],"funders":[{"id":"https://openalex.org/F4320337365","display_name":"National Institute of Dental and Craniofacial Research","ror":"https://ror.org/004a2wv92"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W20629824","https://openalex.org/W140616327","https://openalex.org/W1597387448","https://openalex.org/W1946000001","https://openalex.org/W1964760077","https://openalex.org/W1967606659","https://openalex.org/W1972985959","https://openalex.org/W1998070471","https://openalex.org/W2026243530","https://openalex.org/W2026396276","https://openalex.org/W2030575311","https://openalex.org/W2033202446","https://openalex.org/W2033446143","https://openalex.org/W2052506441","https://openalex.org/W2053996919","https://openalex.org/W2054212814","https://openalex.org/W2064130167","https://openalex.org/W2065714116","https://openalex.org/W2066121955","https://openalex.org/W2067201491","https://openalex.org/W2068143995","https://openalex.org/W2074789448","https://openalex.org/W2074985784","https://openalex.org/W2078599937","https://openalex.org/W2081001452","https://openalex.org/W2091982759","https://openalex.org/W2094668040","https://openalex.org/W2098259948","https://openalex.org/W2107069925","https://openalex.org/W2125350651","https://openalex.org/W2156900283","https://openalex.org/W2156992514","https://openalex.org/W2168398179","https://openalex.org/W2346677443","https://openalex.org/W2411256387","https://openalex.org/W2414959001","https://openalex.org/W2417794794","https://openalex.org/W3132675089"],"related_works":["https://openalex.org/W2064130167","https://openalex.org/W4393381951","https://openalex.org/W2117707789","https://openalex.org/W4389085227","https://openalex.org/W2178437857","https://openalex.org/W2406813363","https://openalex.org/W2122647882","https://openalex.org/W10912772","https://openalex.org/W7024436051","https://openalex.org/W2981499081"],"abstract_inverted_index":{"Extensive":[0],"research":[1],"and":[2,53,77],"clinical":[3],"experience":[4],"have":[5,21],"demonstrated":[6],"the":[7,27,61,64,68,90],"usefulness":[8],"of":[9,29,63,70,83],"sedation":[10],"in":[11,50,92],"helping":[12],"fearful":[13],"patients":[14],"receive":[15],"dental":[16,34,105],"treatment,":[17],"particularly":[18],"when":[19],"they":[20],"urgent":[22],"treatment":[23],"needs.":[24],"In":[25],"addition,":[26],"efficacy":[28],"behavioural":[30,101],"programmes":[31],"for":[32],"managing":[33,104],"fears":[35],"is":[36],"well":[37],"established.":[38],"While":[39],"often":[40],"these":[41,94],"two":[42,65,71],"approaches":[43,102],"are":[44],"seen":[45],"as":[46],"oppositional,":[47],"our":[48],"work":[49],"Seattle,":[51],"Morgantown":[52],"at":[54],"King's":[55],"College":[56],"London":[57],"Dental":[58],"Institute":[59],"demonstrates":[60],"complementarity":[62],"approaches.":[66],"Using":[67],"example":[69],"compounds,":[72],"one":[73,78],"very":[74],"familiar,":[75],"propranolol,":[76],"that":[79],"has":[80],"recently":[81],"become":[82],"interest,":[84],"D-cycloserine,":[85],"we":[86],"wish":[87],"to":[88,99,103],"illustrate":[89],"manner":[91],"which":[93],"medications":[95],"can":[96],"be":[97],"used":[98],"enhance":[100],"anxiety.":[106]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}
