{"id":"https://openalex.org/W2200523834","doi":"https://doi.org/10.1016/j.drudis.2015.12.005","title":"Patent production is a prerequisite for successful exit of a biopharmaceutical company","display_name":"Patent production is a prerequisite for successful exit of a biopharmaceutical company","publication_year":2015,"publication_date":"2015-12-22","ids":{"openalex":"https://openalex.org/W2200523834","doi":"https://doi.org/10.1016/j.drudis.2015.12.005","mag":"2200523834","pmid":"https://pubmed.ncbi.nlm.nih.gov/26721189"},"language":"en","primary_location":{"id":"doi:10.1016/j.drudis.2015.12.005","doi":"https://doi.org/10.1016/j.drudis.2015.12.005","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.drudis.2015.12.005","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1359644615004572/pdf","source":{"id":"https://openalex.org/S152068293","display_name":"Drug Discovery Today","issn_l":"1359-6446","issn":["1359-6446","1878-5832"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drug Discovery Today","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.sciencedirect.com/science/article/pii/S1359644615004572/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055485008","display_name":"Chikako Saotome","orcid":"https://orcid.org/0000-0001-9415-661X","observed_orcids":["https://orcid.org/0000-0001-9415-661X"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Chikako Saotome","raw_affiliation_strings":["Kyoto University Graduate School of Medicine, 53 Kawaharacho, Shogoin, Sakyoku, Kyoto 606-8507, Japan. Electronic address: saotome.chikako.2z@kyoto-u.ac.jp","Kyoto University Graduate School of Medicine, 53 Kawaharacho, Shogoin, Sakyoku, Kyoto 606-8507, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kyoto University Graduate School of Medicine, 53 Kawaharacho, Shogoin, Sakyoku, Kyoto 606-8507, Japan. Electronic address: saotome.chikako.2z@kyoto-u.ac.jp","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"Kyoto University Graduate School of Medicine, 53 Kawaharacho, Shogoin, Sakyoku, Kyoto 606-8507, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066994163","display_name":"Yurie Nakaya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yurie Nakaya","raw_affiliation_strings":["Kyoto University Graduate School of Medicine, 53 Kawaharacho, Shogoin, Sakyoku, Kyoto 606-8507, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kyoto University Graduate School of Medicine, 53 Kawaharacho, Shogoin, Sakyoku, Kyoto 606-8507, Japan","institution_ids":["https://openalex.org/I22299242"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003302142","display_name":"Seiji Abe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Seiji Abe","raw_affiliation_strings":["Kyoto University Graduate School of Medicine, 53 Kawaharacho, Shogoin, Sakyoku, Kyoto 606-8507, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kyoto University Graduate School of Medicine, 53 Kawaharacho, Shogoin, Sakyoku, Kyoto 606-8507, Japan","institution_ids":["https://openalex.org/I22299242"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5055485008"],"corresponding_institution_ids":["https://openalex.org/I22299242"],"apc_list":{"value":4720,"currency":"USD","value_usd":4720},"apc_paid":{"value":4720,"currency":"USD","value_usd":4720},"fwci":1.5513,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.87883696,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"21","issue":"3","first_page":"406","last_page":"409"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10856","display_name":"Intellectual Property and Patents","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/1405","display_name":"Management of Technology and Innovation"},"field":{"id":"https://openalex.org/fields/14","display_name":"Business, Management and Accounting"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10856","display_name":"Intellectual Property and Patents","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/1405","display_name":"Management of Technology and Innovation"},"field":{"id":"https://openalex.org/fields/14","display_name":"Business, Management and Accounting"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11792","display_name":"Pharmaceutical Economics and Policy","score":0.012500000186264515,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T12851","display_name":"Firm Innovation and Growth","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/patents","display_name":"patents","score":0.7160000205039978},{"id":"https://openalex.org/keywords/patent-families","display_name":"patent families","score":0.8740000128746033},{"id":"https://openalex.org/keywords/biopharmaceutical-companies","display_name":"biopharmaceutical companies","score":0.9909999966621399},{"id":"https://openalex.org/keywords/bankruptcy","display_name":"bankruptcy","score":0.8980000019073486},{"id":"https://openalex.org/keywords/mergers-and-acquisitions","display_name":"mergers and acquisitions","score":0.9739999771118164},{"id":"https://openalex.org/keywords/acquisition-cost","display_name":"acquisition cost","score":0.621999979019165},{"id":"https://openalex.org/keywords/patentability","display_name":"patentability","score":0.5870000123977661},{"id":"https://openalex.org/keywords/foreign-patent-applications","display_name":"foreign patent applications","score":0.7919999957084656},{"id":"https://openalex.org/keywords/listed-companies","display_name":"listed companies","score":0.6029999852180481}],"concepts":[{"id":"https://openalex.org/C2781047461","wikidata":"https://www.wikidata.org/wiki/Q679692","display_name":"Biopharmaceutical","level":2,"score":0.9511436223983765},{"id":"https://openalex.org/C504631918","wikidata":"https://www.wikidata.org/wiki/Q152074","display_name":"Bankruptcy","level":2,"score":0.7617680430412292},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.7199664115905762},{"id":"https://openalex.org/C2778348673","wikidata":"https://www.wikidata.org/wiki/Q739302","display_name":"Production (economics)","level":2,"score":0.5056166648864746},{"id":"https://openalex.org/C204983608","wikidata":"https://www.wikidata.org/wiki/Q2111958","display_name":"Productivity","level":2,"score":0.48029014468193054},{"id":"https://openalex.org/C2780697943","wikidata":"https://www.wikidata.org/wiki/Q7144533","display_name":"Patentability","level":4,"score":0.452815443277359},{"id":"https://openalex.org/C90287048","wikidata":"https://www.wikidata.org/wiki/Q197952","display_name":"Corporate group","level":3,"score":0.4483741521835327},{"id":"https://openalex.org/C40700","wikidata":"https://www.wikidata.org/wiki/Q1411783","display_name":"Industrial organization","level":1,"score":0.3694186210632324},{"id":"https://openalex.org/C162853370","wikidata":"https://www.wikidata.org/wiki/Q39809","display_name":"Marketing","level":1,"score":0.3204997181892395},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.2680807113647461},{"id":"https://openalex.org/C34974158","wikidata":"https://www.wikidata.org/wiki/Q131257","display_name":"Intellectual property","level":2,"score":0.24226447939872742},{"id":"https://openalex.org/C10138342","wikidata":"https://www.wikidata.org/wiki/Q43015","display_name":"Finance","level":1,"score":0.1869463324546814},{"id":"https://openalex.org/C2984145337","wikidata":"https://www.wikidata.org/wiki/Q253623","display_name":"Patent law","level":3,"score":0.15325981378555298},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.14801108837127686},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.08893764019012451},{"id":"https://openalex.org/C50522688","wikidata":"https://www.wikidata.org/wiki/Q189833","display_name":"Economic growth","level":1,"score":0.08090069890022278},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07098686695098877},{"id":"https://openalex.org/C39389867","wikidata":"https://www.wikidata.org/wiki/Q380767","display_name":"Corporate governance","level":2,"score":0.06710189580917358},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001688","descriptor_name":"Biological Products","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003132","descriptor_name":"Commerce","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004345","descriptor_name":"Drug Industry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D010330","descriptor_name":"Patents as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.drudis.2015.12.005","doi":"https://doi.org/10.1016/j.drudis.2015.12.005","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.drudis.2015.12.005","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1359644615004572/pdf","source":{"id":"https://openalex.org/S152068293","display_name":"Drug Discovery Today","issn_l":"1359-6446","issn":["1359-6446","1878-5832"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drug Discovery Today","raw_type":"journal-article"},{"id":"pmid:26721189","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26721189","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drug discovery today","raw_type":"Journal Article"},{"id":"pmh:oai:repository.kulib.kyoto-u.ac.jp:2433/292223","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2433/292223","pdf_url":null,"source":{"id":"https://openalex.org/S4306401454","display_name":"Kyoto University Research Information Repository (Kyoto University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I22299242","host_organization_name":"Kyoto University","host_organization_lineage":["https://openalex.org/I22299242"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"journal article"},{"id":"pmh:oai:irdb.nii.ac.jp:01221:0006600684","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2433/292223","pdf_url":null,"source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Drug Discovery Today","raw_type":"journal article"}],"best_oa_location":{"id":"doi:10.1016/j.drudis.2015.12.005","doi":"https://doi.org/10.1016/j.drudis.2015.12.005","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.drudis.2015.12.005","pdf_url":"https://www.sciencedirect.com/science/article/pii/S1359644615004572/pdf","source":{"id":"https://openalex.org/S152068293","display_name":"Drug Discovery Today","issn_l":"1359-6446","issn":["1359-6446","1878-5832"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Drug Discovery Today","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3052024142","display_name":null,"funder_award_id":"00447963","funder_id":"https://openalex.org/F4320307120","funder_display_name":"Aid for Cancer Research"},{"id":"https://openalex.org/G4610130172","display_name":"Research on a patent productivity of biotech companies","funder_award_id":"26380504","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320307120","display_name":"Aid for Cancer Research","ror":"https://ror.org/01yv62k92"},{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2200523834.pdf","grobid_xml":"https://content.openalex.org/works/W2200523834.grobid-xml"},"referenced_works_count":4,"referenced_works":["https://openalex.org/W2003525387","https://openalex.org/W2013290649","https://openalex.org/W2107437045","https://openalex.org/W2146599835"],"related_works":["https://openalex.org/W2765831670","https://openalex.org/W3110051942","https://openalex.org/W2274759474","https://openalex.org/W7220516457","https://openalex.org/W2805852001","https://openalex.org/W1985686774","https://openalex.org/W3159537245","https://openalex.org/W2061111675","https://openalex.org/W2064880718","https://openalex.org/W2385251826"],"abstract_inverted_index":{"Patents":[0],"are":[1,120],"especially":[2],"important":[3],"for":[4,13,135],"the":[5,24,56,61,71,76,85,88,95,101,106,124,127,132],"business":[6,30,43,72],"of":[7,32,39,45,63,75,84,108,116,129,137],"drug":[8],"discovery;":[9],"however,":[10],"their":[11],"importance":[12],"biopharmaceutical":[14,33,48,138],"companies":[15,34,49],"has":[16],"not":[17,121],"been":[18],"revealed":[19],"quantitatively":[20],"yet.":[21],"To":[22],"examine":[23],"correlation":[25],"between":[26],"patents":[27],"and":[28,42,87,90,114],"long-term":[29],"outcome":[31],"we":[35],"analyze":[36],"annual":[37,109],"number":[38,62,107],"patent":[40,64,110,118],"families":[41,65],"conditions":[44],"123":[46],"public-listed":[47],"established":[50],"from":[51],"1990":[52],"to":[53],"1995":[54],"in":[55],"USA.":[57],"Our":[58],"results":[59],"show":[60],"per":[66],"year":[67],"correlates":[68,104],"well":[69],"with":[70,105],"condition:":[73],"average":[74],"bankruptcy":[77],"group":[78],"is":[79,131],"significantly":[80],"smaller":[81],"than":[82],"those":[83],"continuing":[86],"merger":[89],"acquisitions":[91],"(M&A)":[92],"groups.":[93,125],"In":[94],"M&A":[96],"by":[97],"big":[98],"pharma":[99],"group,":[100],"acquisition":[102],"cost":[103],"families.":[111],"However,":[112],"patentability":[113],"strategy":[115],"foreign":[117],"application":[119],"different":[122],"among":[123],"Therefore,":[126],"productivity":[128],"invention":[130],"key":[133],"factor":[134],"success":[136],"companies.":[139]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}