{"id":"https://openalex.org/W2199451964","doi":"https://doi.org/10.21307/immunohematology-2019-136","title":"Alloimmunization of patients by blood units harboring distinct DEL variants","display_name":"Alloimmunization of patients by blood units harboring distinct DEL variants","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2199451964","doi":"https://doi.org/10.21307/immunohematology-2019-136","mag":"2199451964","pmid":"https://pubmed.ncbi.nlm.nih.gov/24689683"},"language":"en","primary_location":{"id":"doi:10.21307/immunohematology-2019-136","doi":"https://doi.org/10.21307/immunohematology-2019-136","is_oa":false,"landing_page_url":"https://doi.org/10.21307/immunohematology-2019-136","pdf_url":null,"source":{"id":"https://openalex.org/S2754767779","display_name":"Immunohematology","issn_l":"0894-203X","issn":["0894-203X","1930-3955"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315546","host_organization_name":"Exeley Inc","host_organization_lineage":["https://openalex.org/P4310315546"],"host_organization_lineage_names":["Exeley Inc"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunohematology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113594140","display_name":"M. St\u2010Louis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1328242539","display_name":"H\u00e9ma-Qu\u00e9bec","ror":"https://ror.org/008jvv944","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I1328242539","https://openalex.org/I2801902503","https://openalex.org/I4210139015"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"M. St-Louis","raw_affiliation_strings":["H\u00e9ma-Qu\u00e9bec , 1070, avenue des Sciences-de-laVie , Qu\u00e9bec (Qu\u00e9bec) , Canada ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"H\u00e9ma-Qu\u00e9bec , 1070, avenue des Sciences-de-laVie , Qu\u00e9bec (Qu\u00e9bec) , Canada ,","institution_ids":["https://openalex.org/I1328242539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110446812","display_name":"Andre J. Lebrun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1328242539","display_name":"H\u00e9ma-Qu\u00e9bec","ror":"https://ror.org/008jvv944","country_code":"CA","type":"nonprofit","lineage":["https://openalex.org/I1328242539","https://openalex.org/I2801902503","https://openalex.org/I4210139015"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"A. Lebrun","raw_affiliation_strings":["Vice-President Medical Affairs Hematology , H\u00e9ma-Qu\u00e9bec , Montr\u00e9al (Qu\u00e9bec) , Canada ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vice-President Medical Affairs Hematology , H\u00e9ma-Qu\u00e9bec , Montr\u00e9al (Qu\u00e9bec) , Canada ,","institution_ids":["https://openalex.org/I1328242539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043247526","display_name":"Mindy Goldman","orcid":"https://orcid.org/0000-0001-9904-9952","observed_orcids":["https://orcid.org/0000-0001-9904-9952"]},"institutions":[{"id":"https://openalex.org/I95297979","display_name":"Canadian Blood Services","ror":"https://ror.org/01jays723","country_code":"CA","type":"funder","lineage":["https://openalex.org/I95297979"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"M. Goldman","raw_affiliation_strings":["Donor and Transplantation Services , Canadian Blood Services , Ottawa (Ontario) , Canada ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Donor and Transplantation Services , Canadian Blood Services , Ottawa (Ontario) , Canada ,","institution_ids":["https://openalex.org/I95297979"]}]},{"author_position":"last","author":{"id":null,"display_name":"M. Lavoie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210093650","display_name":"Centre hospitalier universitaire de Qu\u00e9bec","ror":"https://ror.org/006a7pj43","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801902503","https://openalex.org/I4210093650","https://openalex.org/I4210139015","https://openalex.org/I4405257837","https://openalex.org/I4405279980"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"M. Lavoie","raw_affiliation_strings":["Centre Hospitalier Universitaire de Qu\u00e9bec , Qu\u00e9bec (Qu\u00e9bec) , Canada "],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre Hospitalier Universitaire de Qu\u00e9bec , Qu\u00e9bec (Qu\u00e9bec) , Canada ","institution_ids":["https://openalex.org/I4210093650"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.6389,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.73797835,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"29","issue":"4","first_page":"136","last_page":"140"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11660","display_name":"Blood groups and transfusion","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11660","display_name":"Blood groups and transfusion","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12735","display_name":"Blood donation and transfusion practices","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alloimmunization","display_name":"alloimmunization","score":0.9480000138282776},{"id":"https://openalex.org/keywords/rhd-variants","display_name":"RhD variants","score":0.6970000267028809},{"id":"https://openalex.org/keywords/del-phenotype","display_name":"DEL phenotype","score":0.7390000224113464},{"id":"https://openalex.org/keywords/anti-d","display_name":"anti-D","score":0.5220000147819519},{"id":"https://openalex.org/keywords/rhd-genotyping","display_name":"RhD genotyping","score":0.6179999709129333},{"id":"https://openalex.org/keywords/transfusion-risks","display_name":"transfusion risks","score":0.40799999237060547}],"concepts":[{"id":"https://openalex.org/C31467283","wikidata":"https://www.wikidata.org/wiki/Q912147","display_name":"Genotyping","level":4,"score":0.7548477649688721},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6633114218711853},{"id":"https://openalex.org/C2994072243","wikidata":"https://www.wikidata.org/wiki/Q763244","display_name":"Blood bank","level":2,"score":0.6324158310890198},{"id":"https://openalex.org/C2776557347","wikidata":"https://www.wikidata.org/wiki/Q37187","display_name":"Red blood cell","level":2,"score":0.5759257674217224},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.5636770129203796},{"id":"https://openalex.org/C2780014101","wikidata":"https://www.wikidata.org/wiki/Q183605","display_name":"Blood transfusion","level":2,"score":0.47929471731185913},{"id":"https://openalex.org/C2993617979","wikidata":"https://www.wikidata.org/wiki/Q53467","display_name":"Blood donor","level":2,"score":0.4666682779788971},{"id":"https://openalex.org/C3019670348","wikidata":"https://www.wikidata.org/wiki/Q1024817","display_name":"Blood group antigens","level":3,"score":0.44078707695007324},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4341731071472168},{"id":"https://openalex.org/C121857725","wikidata":"https://www.wikidata.org/wiki/Q425832","display_name":"Rh blood group system","level":3,"score":0.41695451736450195},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.36710408329963684},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2330288589000702},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.23253098130226135},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.22795754671096802},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.184919536113739},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1587238311767578},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.11720514297485352}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001782","descriptor_name":"Blood Donors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001787","descriptor_name":"Blood Group Incompatibility","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001803","descriptor_name":"Blood Transfusion","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005838","descriptor_name":"Genotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007518","descriptor_name":"Isoantibodies","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012204","descriptor_name":"Rh-Hr Blood-Group System","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012204","descriptor_name":"Rh-Hr Blood-Group System","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D018029","descriptor_name":"Rho(D) Immune Globulin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D065227","descriptor_name":"Transfusion Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.21307/immunohematology-2019-136","doi":"https://doi.org/10.21307/immunohematology-2019-136","is_oa":false,"landing_page_url":"https://doi.org/10.21307/immunohematology-2019-136","pdf_url":null,"source":{"id":"https://openalex.org/S2754767779","display_name":"Immunohematology","issn_l":"0894-203X","issn":["0894-203X","1930-3955"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315546","host_organization_name":"Exeley Inc","host_organization_lineage":["https://openalex.org/P4310315546"],"host_organization_lineage_names":["Exeley Inc"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunohematology","raw_type":"journal-article"},{"id":"pmid:24689683","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/24689683","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Immunohematology","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W1545176113","https://openalex.org/W1580509081","https://openalex.org/W1581552278","https://openalex.org/W1842587630","https://openalex.org/W1862441416","https://openalex.org/W1969338900","https://openalex.org/W1972690866","https://openalex.org/W1978710476","https://openalex.org/W1982090182","https://openalex.org/W2006544161","https://openalex.org/W2025405812","https://openalex.org/W2031061849","https://openalex.org/W2049962750","https://openalex.org/W2053575490","https://openalex.org/W2064237753","https://openalex.org/W2072043535","https://openalex.org/W2084930351","https://openalex.org/W2091917999","https://openalex.org/W2092366508","https://openalex.org/W2093181579","https://openalex.org/W2094256042","https://openalex.org/W2121812530","https://openalex.org/W2127036604","https://openalex.org/W2127945724","https://openalex.org/W2147921835","https://openalex.org/W2148525849","https://openalex.org/W2160726543","https://openalex.org/W2169422649","https://openalex.org/W4238559831"],"related_works":["https://openalex.org/W4221067544","https://openalex.org/W2072043535","https://openalex.org/W4387542862","https://openalex.org/W4387806651","https://openalex.org/W2238011004","https://openalex.org/W7221057980","https://openalex.org/W2509202849","https://openalex.org/W1734811546","https://openalex.org/W2349095774","https://openalex.org/W2121812530"],"abstract_inverted_index":{"The":[0],"alloimmunization":[1,69,191,222],"potential":[2,70,192,221],"of":[3,25,71,90,98,137,148,193],"many":[4],"RHD":[5,23,36,88],"variants":[6],"is":[7,59],"unknown,":[8],"and":[9,16,40,49,140],"it":[10],"can":[11],"be":[12,35,213],"explored":[13],"by":[14,85],"lookback":[15],"traceback":[17],"studies.":[18],"Hema-Quebec":[19],"(HQ)":[20,112],"investigated":[21],"the":[22,68,87,115,135,173,180,190,220],"status":[24,89,211],"3980":[26],"D-":[27,100,156],"repeat":[28,145],"blood":[29,102,130,168],"donors.":[30,75],"Thirteen":[31],"were":[32,64,120,126,152],"found":[33,159],"to":[34,66,128,133,141,143,155,217],"positive:":[37],"4":[38],"RHD*1p,":[39],"1":[41,47],"RHD*487delACAG,":[42],"which":[43],"show":[44],"a":[45,53,81,201,204],"Dphenotype;and":[46],"RHD*885T":[48],"7":[50],"RHD*(93-94insT)":[51,165],"causing":[52],"DEL":[54,74,166,175,194,205],"phenotype":[55],"when":[56],"C":[57],"antigen":[58],"present.":[60],"Look":[61],"back":[62,83,182],"studies":[63],"done":[65,109],"verify":[67,134],"these":[72],"eight":[73],"Coincidentally,":[76],"Canadian":[77],"Blood":[78],"Services":[79],"(CBS)performed":[80],"trace":[82,181],"study":[84],"investigating":[86],"donors":[91,142],"after":[92],"aD-":[93],"recipient":[94],"developed":[95],"anti-Dafter":[96],"transfusion":[97],"two":[99],"red":[101,167],"cell":[103],"(RBC)":[104],"units.":[105],"Donor":[106],"genotyping":[107],"was":[108,158,177],"either":[110],"manually":[111],"or":[113,198,208],"using":[114],"Progenika":[116],"Bloodchip":[117],"platform(CBS).":[118],"Donations":[119],"traced":[121],"through":[122],"computer":[123],"records.":[124],"Letters":[125],"sent":[127],"hospital":[129],"bank":[131],"physicians":[132],"presence":[136],"anti-Din":[138],"recipients":[139],"request":[144],"samples.A":[146],"total":[147],"118":[149],"RBC":[150],"units":[151],"transfused,":[153],"82":[154],"recipients.Anti-D":[157],"in":[160,179],"three":[161],"patients":[162],"transfused":[163],"with":[164],"cells.":[169],"One":[170],"donor":[171,202],"presenting":[172],"same":[174],"variant":[176],"involved":[178],"study.":[183],"Even":[184],"without":[185],"strong":[186],"evidence":[187],"clearly":[188],"demonstrating":[189],"variants,":[195],"whenever":[196],"HQ":[197],"CBS":[199],"identifies":[200],"harboring":[203],"phenotype,":[206],"his":[207],"her":[209],"D":[210],"will":[212],"changed":[214],"from":[215],"DtoD+":[216],"protect":[218],"against":[219],"risk.":[223]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}