{"id":"https://openalex.org/W2199200166","doi":"https://doi.org/10.1007/978-1-4615-4863-8_76","title":"Use of Oxygen-15-Labeled Molecular Oxygen for Oxygen Delivery Studies of Blood and Blood Substitutes","display_name":"Use of Oxygen-15-Labeled Molecular Oxygen for Oxygen Delivery Studies of Blood and Blood Substitutes","publication_year":1998,"publication_date":"1998-01-01","ids":{"openalex":"https://openalex.org/W2199200166","doi":"https://doi.org/10.1007/978-1-4615-4863-8_76","mag":"2199200166","pmid":"https://pubmed.ncbi.nlm.nih.gov/9889945"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4615-4863-8_76","doi":"https://doi.org/10.1007/978-1-4615-4863-8_76","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4615-4863-8_76","pdf_url":null,"source":{"id":"https://openalex.org/S43790123","display_name":"Advances in experimental medicine and biology","issn_l":"0065-2598","issn":["0065-2598","2214-8019"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Experimental Medicine and Biology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W1996362072","display_name":"Oxygen Transport to Tissue XX"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054573497","display_name":"Beth Goins","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B. Goins","raw_affiliation_strings":["Department of Radiology, University of Texas Health Science Center at San Antonio 78284, USA","Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78284, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, University of Texas Health Science Center at San Antonio 78284, USA","institution_ids":["https://openalex.org/I165951966"]},{"raw_affiliation_string":"Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78284, USA","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054669946","display_name":"Robert W. Klipper","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. Klipper","raw_affiliation_strings":["Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78284, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78284, USA","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111644841","display_name":"C. Martin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. Martin","raw_affiliation_strings":["Research Imaging Center, University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78284, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Imaging Center, University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78284, USA","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"middle","author":{"id":null,"display_name":"P. A. Jerabek","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P. A. Jerabek","raw_affiliation_strings":["Research Imaging Center, University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78284, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Imaging Center, University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78284, USA","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008235250","display_name":"S. Khalvati","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Khalvati","raw_affiliation_strings":["Research Imaging Center, University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78284, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Imaging Center, University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78284, USA","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014310950","display_name":"Peter T. Fox","orcid":"https://orcid.org/0000-0002-0465-2028","observed_orcids":["https://orcid.org/0000-0002-0465-2028"]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P. T. Fox","raw_affiliation_strings":["Research Imaging Center, University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78284, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Imaging Center, University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78284, USA","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064217558","display_name":"Richard O. Cliff","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1288214837","display_name":"United States Naval Research Laboratory","ror":"https://ror.org/04d23a975","country_code":"US","type":"facility","lineage":["https://openalex.org/I1288214837","https://openalex.org/I1330347796","https://openalex.org/I175003984","https://openalex.org/I3130687028"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R. O. Cliff","raw_affiliation_strings":["Center For Biomolecular Science and Engineering, Naval Research Laboratory, Washington, D.C., 20375, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center For Biomolecular Science and Engineering, Naval Research Laboratory, Washington, D.C., 20375, USA","institution_ids":["https://openalex.org/I1288214837"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084989668","display_name":"Victoria Kwasiborski","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1288214837","display_name":"United States Naval Research Laboratory","ror":"https://ror.org/04d23a975","country_code":"US","type":"facility","lineage":["https://openalex.org/I1288214837","https://openalex.org/I1330347796","https://openalex.org/I175003984","https://openalex.org/I3130687028"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"V. Kwasiborski","raw_affiliation_strings":["Center For Biomolecular Science and Engineering, Naval Research Laboratory, Washington, D.C., 20375, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center For Biomolecular Science and Engineering, Naval Research Laboratory, Washington, D.C., 20375, USA","institution_ids":["https://openalex.org/I1288214837"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110101086","display_name":"Alan S. Rudolph","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1288214837","display_name":"United States Naval Research Laboratory","ror":"https://ror.org/04d23a975","country_code":"US","type":"facility","lineage":["https://openalex.org/I1288214837","https://openalex.org/I1330347796","https://openalex.org/I175003984","https://openalex.org/I3130687028"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. S. Rudolph","raw_affiliation_strings":["Center For Biomolecular Science and Engineering, Naval Research Laboratory, Washington, D.C., 20375, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center For Biomolecular Science and Engineering, Naval Research Laboratory, Washington, D.C., 20375, USA","institution_ids":["https://openalex.org/I1288214837"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048202536","display_name":"William Thomas Phillips","orcid":"https://orcid.org/0000-0001-8248-7817","observed_orcids":["https://orcid.org/0000-0001-8248-7817"]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W. T. Phillips","raw_affiliation_strings":["Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78284, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, 78284, USA","institution_ids":["https://openalex.org/I165951966"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.20948617,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"454","issue":null,"first_page":"643","last_page":"652"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12094","display_name":"Hemoglobin structure and function","score":0.5073000192642212,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12094","display_name":"Hemoglobin structure and function","score":0.5073000192642212,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10977","display_name":"Optical Imaging and Spectroscopy Techniques","score":0.13289999961853027,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12930","display_name":"Biomedical and Chemical Research","score":0.05559999868273735,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oxygen-15","display_name":"oxygen-15","score":0.6690000295639038},{"id":"https://openalex.org/keywords/molecular-oxygen","display_name":"molecular oxygen","score":0.7839999794960022},{"id":"https://openalex.org/keywords/blood-substitutes","display_name":"blood substitutes","score":0.8360000252723694},{"id":"https://openalex.org/keywords/oxygen-delivery","display_name":"oxygen delivery","score":0.9520000219345093},{"id":"https://openalex.org/keywords/oxygen-carriers","display_name":"oxygen carriers","score":0.6759999990463257},{"id":"https://openalex.org/keywords/tissue-oxygenation","display_name":"tissue oxygenation","score":0.8450000286102295},{"id":"https://openalex.org/keywords/erythrocytes","display_name":"erythrocytes","score":0.8500000238418579},{"id":"https://openalex.org/keywords/oxygen-consumption","display_name":"oxygen consumption","score":0.550000011920929},{"id":"https://openalex.org/keywords/combat-casualty-care","display_name":"combat casualty care","score":0.48100000619888306}],"concepts":[{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.6973074674606323},{"id":"https://openalex.org/C2994142871","wikidata":"https://www.wikidata.org/wiki/Q7873","display_name":"Oxygen delivery","level":3,"score":0.48581457138061523},{"id":"https://openalex.org/C1621761","wikidata":"https://www.wikidata.org/wiki/Q7997549","display_name":"Whole blood","level":2,"score":0.47651636600494385},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.46147724986076355},{"id":"https://openalex.org/C70289976","wikidata":"https://www.wikidata.org/wiki/Q17143603","display_name":"Oxygenation","level":2,"score":0.4500999450683594},{"id":"https://openalex.org/C2778337571","wikidata":"https://www.wikidata.org/wiki/Q831050","display_name":"Blood substitute","level":3,"score":0.446688711643219},{"id":"https://openalex.org/C121745418","wikidata":"https://www.wikidata.org/wiki/Q585536","display_name":"Quenching (fluorescence)","level":3,"score":0.4364803731441498},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34363529086112976},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3431949019432068},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2766960859298706},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.24375233054161072},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.1753421425819397},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.08755788207054138},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001802","descriptor_name":"Blood Substitutes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005078","descriptor_name":"Exchange Transfusion, Whole Blood","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006454","descriptor_name":"Hemoglobins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008081","descriptor_name":"Liposomes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010100","descriptor_name":"Oxygen","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D010104","descriptor_name":"Oxygen Radioisotopes","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":true},{"descriptor_ui":"D010108","descriptor_name":"Oxyhemoglobins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/978-1-4615-4863-8_76","doi":"https://doi.org/10.1007/978-1-4615-4863-8_76","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4615-4863-8_76","pdf_url":null,"source":{"id":"https://openalex.org/S43790123","display_name":"Advances in experimental medicine and biology","issn_l":"0065-2598","issn":["0065-2598","2214-8019"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Experimental Medicine and Biology","raw_type":"book-chapter"},{"id":"pmid:9889945","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9889945","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in experimental medicine and biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5683000087738037}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5400000214576721}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2504990260","display_name":null,"funder_award_id":"R01HL53052","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7182571541","display_name":"PLATELET INTERACTION AND EFFICACY STUDIES OF LEH","funder_award_id":"5r01hl053052-03","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W33045538","https://openalex.org/W637987249","https://openalex.org/W1147337017","https://openalex.org/W1557910602","https://openalex.org/W1587882030","https://openalex.org/W1905631108","https://openalex.org/W2004118876","https://openalex.org/W2014450669","https://openalex.org/W2046555684","https://openalex.org/W2053655750","https://openalex.org/W2130409056","https://openalex.org/W2436046287","https://openalex.org/W4242134579","https://openalex.org/W4294704644","https://openalex.org/W4302457680"],"related_works":["https://openalex.org/W1972291858","https://openalex.org/W2130409056","https://openalex.org/W2728888199","https://openalex.org/W2145038796","https://openalex.org/W4240498871","https://openalex.org/W2395502943","https://openalex.org/W2019992851","https://openalex.org/W2274226329","https://openalex.org/W1996037648","https://openalex.org/W562641976"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}