{"id":"https://openalex.org/W2197486153","doi":null,"title":"Relationship between interleukin-1beta and lipids in type 1 diabetic patients.","display_name":"Relationship between interleukin-1beta and lipids in type 1 diabetic patients.","publication_year":2007,"publication_date":"2007-08-01","ids":{"openalex":"https://openalex.org/W2197486153","mag":"2197486153","pmid":"https://pubmed.ncbi.nlm.nih.gov/17660728"},"language":"en","primary_location":{"id":"pmid:17660728","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17660728","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical science monitor : international medical journal of experimental and clinical research","raw_type":"Journal Article"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046980798","display_name":"Mourad Aribi","orcid":"https://orcid.org/0000-0002-6522-7252","observed_orcids":["https://orcid.org/0000-0002-6522-7252"]},"institutions":[{"id":"https://openalex.org/I233209018","display_name":"University of Abou Bekr Belka\u00efd","ror":"https://ror.org/00jsjm362","country_code":"DZ","type":"education","lineage":["https://openalex.org/I233209018"]},{"id":"https://openalex.org/I4210125514","display_name":"Universit\u00e9 Djilali de Sidi Bel Abb\u00e8s","ror":"https://ror.org/0378szg41","country_code":"DZ","type":"education","lineage":["https://openalex.org/I4210125514"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Mourad Aribi","raw_affiliation_strings":["Department of Biology, Djillali Liabes University, Biotoxicology Laboratory, National Research Center, Sidi-Bel-Abbes, Algeria","Department of Biology, Djillali Liabes University, Biotoxicology Laboratory, National Research Center, Sidi-Bel-Abbes, Algeria and Department of Pharmacy, Abou-Bekr Belakaid University, Tlemcen, Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Djillali Liabes University, Biotoxicology Laboratory, National Research Center, Sidi-Bel-Abbes, Algeria","institution_ids":["https://openalex.org/I4210125514"]},{"raw_affiliation_string":"Department of Biology, Djillali Liabes University, Biotoxicology Laboratory, National Research Center, Sidi-Bel-Abbes, Algeria and Department of Pharmacy, Abou-Bekr Belakaid University, Tlemcen, Algeria","institution_ids":["https://openalex.org/I233209018","https://openalex.org/I4210125514"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057545142","display_name":"Soraya Moulessehoul","orcid":"https://orcid.org/0009-0007-0024-5146","observed_orcids":["https://orcid.org/0009-0007-0024-5146"]},"institutions":[{"id":"https://openalex.org/I4210125514","display_name":"Universit\u00e9 Djilali de Sidi Bel Abb\u00e8s","ror":"https://ror.org/0378szg41","country_code":"DZ","type":"education","lineage":["https://openalex.org/I4210125514"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Soraya Moulessehoul","raw_affiliation_strings":["Department of Biology, Djillali Liabes University, Biotoxicology Laboratory, National Research Center, Sidi-Bel-Abbes, Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Djillali Liabes University, Biotoxicology Laboratory, National Research Center, Sidi-Bel-Abbes, Algeria","institution_ids":["https://openalex.org/I4210125514"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088914271","display_name":"Mohammed Kendouci-Tani","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I233209018","display_name":"University of Abou Bekr Belka\u00efd","ror":"https://ror.org/00jsjm362","country_code":"DZ","type":"education","lineage":["https://openalex.org/I233209018"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Mohammed Kendouci-Tani","raw_affiliation_strings":["Department of Medicine, Internal Medicine Board, University Medical Center of Tlemcen, Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Internal Medicine Board, University Medical Center of Tlemcen, Algeria","institution_ids":["https://openalex.org/I233209018"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080036475","display_name":"Ahmed-Bakir Benabadji","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I233209018","display_name":"University of Abou Bekr Belka\u00efd","ror":"https://ror.org/00jsjm362","country_code":"DZ","type":"education","lineage":["https://openalex.org/I233209018"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Ahmed-Bakir Benabadji","raw_affiliation_strings":["Department of Pharmacy, Abou-Bekr Belakaid University, Tlemcen, Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, Abou-Bekr Belakaid University, Tlemcen, Algeria","institution_ids":["https://openalex.org/I233209018"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089518272","display_name":"Aziz Hichami","orcid":"https://orcid.org/0000-0003-4331-5152","observed_orcids":["https://orcid.org/0000-0003-4331-5152"]},"institutions":[{"id":"https://openalex.org/I177064439","display_name":"Universit\u00e9 de Bourgogne","ror":"https://ror.org/03k1bsr36","country_code":"FR","type":"education","lineage":["https://openalex.org/I177064439","https://openalex.org/I4405253280"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Aziz Hichami","raw_affiliation_strings":["Lipids and Cell Signaling, UFR Sciences de la vie, Universit\u00e9 de Bourgogne, Dijon, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lipids and Cell Signaling, UFR Sciences de la vie, Universit\u00e9 de Bourgogne, Dijon, France","institution_ids":["https://openalex.org/I177064439"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015564038","display_name":"Naim A. Khan","orcid":"https://orcid.org/0000-0002-8930-9332","observed_orcids":["https://orcid.org/0000-0002-8930-9332"]},"institutions":[{"id":"https://openalex.org/I177064439","display_name":"Universit\u00e9 de Bourgogne","ror":"https://ror.org/03k1bsr36","country_code":"FR","type":"education","lineage":["https://openalex.org/I177064439","https://openalex.org/I4405253280"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Naim Akhtar Khan","raw_affiliation_strings":["Lipids and Cell Signaling, UFR Sciences de la vie, Universit\u00e9 de Bourgogne, Dijon, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lipids and Cell Signaling, UFR Sciences de la vie, Universit\u00e9 de Bourgogne, Dijon, France","institution_ids":["https://openalex.org/I177064439"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.8929,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.76110462,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"13","issue":"8","first_page":"CR372","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11171","display_name":"Diabetes and associated disorders","score":0.9564999938011169,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11171","display_name":"Diabetes and associated disorders","score":0.9564999938011169,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.02710000053048134,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.010499999858438969,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interleukin-1beta","display_name":"IL-1\u03b2","score":0.9449999928474426},{"id":"https://openalex.org/keywords/type-1-diabetes","display_name":"type 1 diabetes","score":0.9940000176429749},{"id":"https://openalex.org/keywords/circulating-lipids","display_name":"circulating lipids","score":0.9509999752044678},{"id":"https://openalex.org/keywords/cholesterol","display_name":"cholesterol","score":0.5130000114440918},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.9860000014305115},{"id":"https://openalex.org/keywords/hdl-cholesterol","display_name":"HDL cholesterol","score":0.9269999861717224},{"id":"https://openalex.org/keywords/triglycerides","display_name":"triglycerides","score":0.9909999966621399},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.9810000061988831},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.5460000038146973},{"id":"https://openalex.org/keywords/disease-duration","display_name":"disease duration","score":0.8119999766349792},{"id":"https://openalex.org/keywords/newly-diagnosed-diabetes","display_name":"newly diagnosed diabetes","score":0.8209999799728394},{"id":"https://openalex.org/keywords/hba1c","display_name":"HbA1c","score":0.8460000157356262}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7773619294166565},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6377004384994507},{"id":"https://openalex.org/C2781232474","wikidata":"https://www.wikidata.org/wiki/Q124407","display_name":"Type 1 diabetes","level":3,"score":0.5923179984092712},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5807196497917175},{"id":"https://openalex.org/C3020110884","wikidata":"https://www.wikidata.org/wiki/Q695416","display_name":"Outpatient clinic","level":2,"score":0.5794692039489746},{"id":"https://openalex.org/C74172505","wikidata":"https://www.wikidata.org/wiki/Q194908","display_name":"Interleukin","level":3,"score":0.4722520709037781},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4451625347137451},{"id":"https://openalex.org/C2778270857","wikidata":"https://www.wikidata.org/wiki/Q2723972","display_name":"Lipid profile","level":3,"score":0.42261937260627747},{"id":"https://openalex.org/C146304588","wikidata":"https://www.wikidata.org/wiki/Q961652","display_name":"Case-control study","level":2,"score":0.4194284975528717},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4149476885795593},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.399943470954895},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.3973050117492676},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.36862897872924805},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.2184332311153412}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001327","descriptor_name":"Autoimmune Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002097","descriptor_name":"C-Reactive Protein","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003922","descriptor_name":"Diabetes Mellitus, Type 1","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006442","descriptor_name":"Glycated Hemoglobin","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008055","descriptor_name":"Lipids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015233","descriptor_name":"Models, Statistical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D053583","descriptor_name":"Interleukin-1beta","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D053583","descriptor_name":"Interleukin-1beta","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:17660728","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17660728","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical science monitor : international medical journal of experimental and clinical research","raw_type":"Journal Article"},{"id":"mag:2197486153","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17660728","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4214722146","https://openalex.org/W2071663190","https://openalex.org/W3183398051","https://openalex.org/W2511126158","https://openalex.org/W4205490074","https://openalex.org/W4415271728","https://openalex.org/W2033252213","https://openalex.org/W2897722170","https://openalex.org/W2110346429","https://openalex.org/W2036009783"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,32,86],"auto-immune":[2],"response":[3],"leading":[4],"to":[5,39,116,214],"type":[6,219],"1":[7,220],"diabetes":[8,221],"(T1D)":[9],"is":[10,43],"closely":[11],"associated":[12,44,118,216],"with":[13,45,119,196,204,217],"the":[14,46,49,55,74,108,149,185,218,239],"overproduction":[15],"of":[16,25,35,48,52,77,88,97,188,192,206,241],"T":[17],"helper-1":[18],"(Th1)":[19],"cytokines":[20],"which":[21],"activate":[22],"macrophage":[23],"production":[24],"inflammatory":[26,50,222],"mediators":[27],"such":[28],"as":[29,236,238],"interleukin":[30],"(IL)-1beta.":[31],"principal":[33],"aim":[34],"this":[36,242],"study":[37],"was":[38],"elucidate":[40],"whether":[41],"IL-1beta":[42,111,212],"development":[47],"state":[51],"disease":[53],"and":[54,65,93,112,136,141,155,179,202,232,244],"altered":[56],"circulating":[57,245],"lipid":[58],"levels":[59,87,143,201,240],"in":[60,102,107,148,161,165,173,177,208],"T1D.":[61],"MATERIAL/METHODS:":[62],"Sixty-nine":[63],"T1D":[64,104,120,124,209,234],"74":[66],"age-matched":[67],"non-diabetic":[68],"(ND)":[69],"subjects":[70,105,125],"were":[71,99,114,144,158,171],"recruited":[72],"from":[73],"outpatient":[75],"department":[76],"Internal":[78],"Medicine,":[79],"University":[80],"Medical":[81],"Center,":[82],"Tlemcen,":[83],"Algeria.":[84],"RESULTS:":[85],"IL-1beta,":[89,129,189],"CRP,":[90,132,193],"HbA1c,":[91],"CHOL,":[92,197],"LDLc,":[94,198],"but":[95,130,190],"not":[96,131,145,191],"HDLc,":[98],"significantly":[100,127,159],"higher":[101,128,160],"all":[103],"than":[106,134,164,176],"ND":[109],"controls.":[110],"CRP":[113,207],"found":[115],"be":[117,215],"(OR>1).":[121],"Newly":[122],"diagnosed":[123,167,181,231],"exhibited":[126],"concentrations":[133,157,187],"controls":[135,178],"long-standing":[137,162,174,233],"diabetic":[138,151,182],"subjects.":[139,183],"TG":[140,200],"HbA1c":[142],"statistically":[146],"different":[147],"two":[150],"populations.":[152],"However,":[153],"CHOL":[154],"LDLc":[156],"patients":[163,175,235],"newly":[166,180,230],"ones.":[168],"HDLc":[169],"fractions":[170],"lower":[172],"Furthermore,":[184],"plasmatic":[186],"negatively":[194],"correlated":[195],"or":[199],"positively":[203],"those":[205],"patients.":[210],"CONCLUSIONS:":[211],"seems":[213],"process.":[223],"Moreover,":[224],"a":[225],"reciprocal":[226],"relationship":[227],"exists":[228],"between":[229],"far":[237],"cytokine":[243],"lipids":[246],"are":[247],"concerned.":[248]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}