{"id":"https://openalex.org/W2196949355","doi":null,"title":"Effect of carrageenan on activity of the mononuclear phagocyte system in the mouse.","display_name":"Effect of carrageenan on activity of the mononuclear phagocyte system in the mouse.","publication_year":1978,"publication_date":"1978-04-01","ids":{"openalex":"https://openalex.org/W2196949355","mag":"2196949355","pmid":"https://pubmed.ncbi.nlm.nih.gov/656321","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2041325"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2041325","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2041325","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Br J Exp Pathol","raw_type":"Text"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2041325","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"E F Fowler","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E F Fowler","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5069651723","display_name":"Angus W. Thomson","orcid":"https://orcid.org/0000-0001-6731-8871","observed_orcids":["https://orcid.org/0000-0001-6731-8871"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A W Thomson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.7097,"has_fulltext":false,"cited_by_count":37,"citation_normalized_percentile":{"value":0.84009667,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"59","issue":"2","first_page":"213","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12672","display_name":"Phagocytosis and Immune Regulation","score":0.513700008392334,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12672","display_name":"Phagocytosis and Immune Regulation","score":0.513700008392334,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses","score":0.2264000028371811,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.08839999884366989,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carrageenan","display_name":"carrageenan","score":0.9990000128746033},{"id":"https://openalex.org/keywords/reticuloendothelial-system","display_name":"reticuloendothelial system","score":0.996999979019165},{"id":"https://openalex.org/keywords/kupffer-cells","display_name":"Kupffer cells","score":0.9760000109672546},{"id":"https://openalex.org/keywords/hepatosplenomegaly","display_name":"hepatosplenomegaly","score":0.9879999756813049},{"id":"https://openalex.org/keywords/thymic-involution","display_name":"thymic involution","score":0.9929999709129333},{"id":"https://openalex.org/keywords/sheep-red-blood-cells","display_name":"sheep red blood cells","score":0.8230000138282776},{"id":"https://openalex.org/keywords/colloidal-carbon","display_name":"colloidal carbon","score":0.800000011920929},{"id":"https://openalex.org/keywords/spleen","display_name":"spleen","score":0.7919999957084656}],"concepts":[{"id":"https://openalex.org/C19702531","wikidata":"https://www.wikidata.org/wiki/Q929966","display_name":"Mononuclear phagocyte system","level":2,"score":0.9535822868347168},{"id":"https://openalex.org/C2781227287","wikidata":"https://www.wikidata.org/wiki/Q421991","display_name":"Carrageenan","level":2,"score":0.7929038405418396},{"id":"https://openalex.org/C160448771","wikidata":"https://www.wikidata.org/wiki/Q184726","display_name":"Phagocytosis","level":2,"score":0.7532201409339905},{"id":"https://openalex.org/C2780931953","wikidata":"https://www.wikidata.org/wiki/Q9371","display_name":"Spleen","level":2,"score":0.6939671635627747},{"id":"https://openalex.org/C2781409172","wikidata":"https://www.wikidata.org/wiki/Q17056802","display_name":"Involution (esoterism)","level":3,"score":0.5991345047950745},{"id":"https://openalex.org/C2777700362","wikidata":"https://www.wikidata.org/wiki/Q107647","display_name":"Phagocyte","level":3,"score":0.5525036454200745},{"id":"https://openalex.org/C137061746","wikidata":"https://www.wikidata.org/wiki/Q736033","display_name":"Peripheral blood mononuclear cell","level":3,"score":0.48100098967552185},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4526382386684418},{"id":"https://openalex.org/C2778904781","wikidata":"https://www.wikidata.org/wiki/Q513486","display_name":"Kupffer cell","level":2,"score":0.4414239823818207},{"id":"https://openalex.org/C2778468042","wikidata":"https://www.wikidata.org/wiki/Q273976","display_name":"Blockade","level":3,"score":0.41644155979156494},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4107283651828766},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3487924337387085},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3312775492668152},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.313198983669281},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.27837711572647095},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.24285337328910828},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16177663207054138},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.1182871162891388},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.08667129278182983},{"id":"https://openalex.org/C186720457","wikidata":"https://www.wikidata.org/wiki/Q7087","display_name":"Consciousness","level":2,"score":0.0},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002244","descriptor_name":"Carbon","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002351","descriptor_name":"Carrageenan","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D003864","descriptor_name":"Depression, Chemical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008099","descriptor_name":"Liver","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D009929","descriptor_name":"Organ Size","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010587","descriptor_name":"Phagocytosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:2041325","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2041325","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Br J Exp Pathol","raw_type":"Text"},{"id":"pmid:656321","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/656321","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British journal of experimental pathology","raw_type":"Journal Article"},{"id":"mag:2196949355","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/656321","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2041325","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2041325","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Br J Exp Pathol","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W24165031","https://openalex.org/W68445933","https://openalex.org/W142314628","https://openalex.org/W146652658","https://openalex.org/W278994876","https://openalex.org/W1518291377","https://openalex.org/W1601639127","https://openalex.org/W1694827920","https://openalex.org/W2004757943","https://openalex.org/W2028957549","https://openalex.org/W2041117923","https://openalex.org/W2044696409","https://openalex.org/W2069558318","https://openalex.org/W2080959072","https://openalex.org/W2089999770","https://openalex.org/W2111031157","https://openalex.org/W2267841716","https://openalex.org/W2399962260","https://openalex.org/W2409484886","https://openalex.org/W2414246928","https://openalex.org/W2416594573","https://openalex.org/W4245252069"],"related_works":["https://openalex.org/W146652658","https://openalex.org/W2403926544","https://openalex.org/W2303606280","https://openalex.org/W2023092802","https://openalex.org/W2134255763","https://openalex.org/W1597375959","https://openalex.org/W1558503283","https://openalex.org/W97392005","https://openalex.org/W2172719869","https://openalex.org/W1996938266"],"abstract_inverted_index":{"Injection":[0],"of":[1,15,30,43,53,66,73],"5":[2],"mg":[3],"carrageenan":[4,50,58],"caused":[5],"hepatosplenomegaly":[6],"and":[7,10,35,55,59],"thymic":[8],"involution":[9],"resulted":[11],"in":[12,63],"temporary":[13],"blockade":[14],"the":[16,77],"mononuclear":[17],"phagocyte":[18],"system":[19],"(MPS).":[20],"Impaired":[21],"MPS":[22],"activity":[23,46],"was":[24,47,68],"shown":[25],"by":[26,70],"decreased":[27],"hepatic":[28,64],"phagocytosis":[29],"i.v.":[31],"injected":[32],"colloidal":[33],"carbon":[34],"51Cr-labelled":[36],"sheep":[37],"red":[38],"blood":[39],"cells":[40,75],"(SRBC).":[41],"Depression":[42],"Kupffer":[44],"cell":[45],"dependent":[48],"on":[49],"dose,":[51],"route":[52],"administration":[54],"interval":[56],"between":[57],"particle":[60],"injection.":[61],"Reduction":[62],"uptake":[65],"SRBC":[67],"accompanied":[69],"increased":[71],"localization":[72],"these":[74],"within":[76],"spleen.":[78]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}