{"id":"https://openalex.org/W2195370592","doi":"https://doi.org/10.1124/mol.115.099549","title":"AMPK Inhibits the Stimulatory Effects of TGF-\u03b2 on Smad2/3 Activity, Cell Migration, and Epithelial-to-Mesenchymal Transition","display_name":"AMPK Inhibits the Stimulatory Effects of TGF-\u03b2 on Smad2/3 Activity, Cell Migration, and Epithelial-to-Mesenchymal Transition","publication_year":2015,"publication_date":"2015-10-01","ids":{"openalex":"https://openalex.org/W2195370592","doi":"https://doi.org/10.1124/mol.115.099549","mag":"2195370592","pmid":"https://pubmed.ncbi.nlm.nih.gov/26424816","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4658597"},"language":"en","primary_location":{"id":"doi:10.1124/mol.115.099549","doi":"https://doi.org/10.1124/mol.115.099549","is_oa":true,"landing_page_url":"https://doi.org/10.1124/mol.115.099549","pdf_url":"https://molpharm.aspetjournals.org/content/molpharm/88/6/1062.full.pdf","source":{"id":"https://openalex.org/S62949411","display_name":"Molecular Pharmacology","issn_l":"0026-895X","issn":["0026-895X","1521-0111"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316283","host_organization_name":"American Society for Pharmacology and Experimental Therapeutics","host_organization_lineage":["https://openalex.org/P4310316283"],"host_organization_lineage_names":["American Society for Pharmacology and Experimental Therapeutics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Pharmacology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://molpharm.aspetjournals.org/content/molpharm/88/6/1062.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010983049","display_name":"Hui Lin","orcid":"https://orcid.org/0000-0003-0343-1757","observed_orcids":["https://orcid.org/0000-0003-0343-1757"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]},{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Hui Lin","raw_affiliation_strings":["Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.); Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.)","Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.); Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I12912129","https://openalex.org/I141649914"]},{"raw_affiliation_string":"Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.)","institution_ids":[]},{"raw_affiliation_string":"Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I12912129","https://openalex.org/I141649914"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035341249","display_name":"Nianshuang Li","orcid":"https://orcid.org/0000-0001-7343-9311","observed_orcids":["https://orcid.org/0000-0001-7343-9311"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]},{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Nianshuang Li","raw_affiliation_strings":["Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.); Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.)","Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.); Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I12912129","https://openalex.org/I141649914"]},{"raw_affiliation_string":"Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.)","institution_ids":[]},{"raw_affiliation_string":"Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I12912129","https://openalex.org/I141649914"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101874423","display_name":"Huan He","orcid":"https://orcid.org/0000-0003-1147-903X","observed_orcids":["https://orcid.org/0000-0003-1147-903X"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]},{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Huan He","raw_affiliation_strings":["Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.); Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.)","Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.); Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I12912129","https://openalex.org/I141649914"]},{"raw_affiliation_string":"Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.)","institution_ids":[]},{"raw_affiliation_string":"Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I12912129","https://openalex.org/I141649914"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101755132","display_name":"Ying Ying","orcid":"https://orcid.org/0000-0002-0113-4866","observed_orcids":["https://orcid.org/0000-0002-0113-4866"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]},{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Ying Ying","raw_affiliation_strings":["Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.); Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.)","Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.); Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I12912129","https://openalex.org/I141649914"]},{"raw_affiliation_string":"Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.)","institution_ids":[]},{"raw_affiliation_string":"Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I12912129","https://openalex.org/I141649914"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040727774","display_name":"Shashank Sunkara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]},{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Shashank Sunkara","raw_affiliation_strings":["Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.); Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.)","Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.); Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I12912129","https://openalex.org/I141649914"]},{"raw_affiliation_string":"Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.)","institution_ids":[]},{"raw_affiliation_string":"Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I12912129","https://openalex.org/I141649914"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102058476","display_name":"Lingyu Luo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]},{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Lingyu Luo","raw_affiliation_strings":["Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.); Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.)","Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.); Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I12912129","https://openalex.org/I141649914"]},{"raw_affiliation_string":"Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.)","institution_ids":[]},{"raw_affiliation_string":"Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I12912129","https://openalex.org/I141649914"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111776765","display_name":"Nonghua Lv","orcid":"https://orcid.org/0000-0001-7405-4069","observed_orcids":["https://orcid.org/0000-0001-7405-4069"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]},{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Nonghua Lv","raw_affiliation_strings":["Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.); Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.)","Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.); Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I12912129","https://openalex.org/I141649914"]},{"raw_affiliation_string":"Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.)","institution_ids":[]},{"raw_affiliation_string":"Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I12912129","https://openalex.org/I141649914"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108589608","display_name":"Deqiang Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]},{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]},{"id":"https://openalex.org/I9224756","display_name":"Northeastern University","ror":"https://ror.org/03awzbc87","country_code":"CN","type":"education","lineage":["https://openalex.org/I9224756"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Deqiang Huang","raw_affiliation_strings":["Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.); Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts zluo@bu.edu hdq0515@163.com","Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.)","Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.); Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts zluo@bu.edu hdq0515@163.com","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I12912129","https://openalex.org/I141649914","https://openalex.org/I9224756"]},{"raw_affiliation_string":"Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.)","institution_ids":[]},{"raw_affiliation_string":"Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I12912129","https://openalex.org/I141649914"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043860726","display_name":"Zhijun Luo","orcid":"https://orcid.org/0000-0001-8105-5289","observed_orcids":["https://orcid.org/0000-0001-8105-5289"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]},{"id":"https://openalex.org/I12912129","display_name":"Northeastern University","ror":"https://ror.org/04t5xt781","country_code":"US","type":"education","lineage":["https://openalex.org/I12912129"]},{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]},{"id":"https://openalex.org/I9224756","display_name":"Northeastern University","ror":"https://ror.org/03awzbc87","country_code":"CN","type":"education","lineage":["https://openalex.org/I9224756"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Zhijun Luo","raw_affiliation_strings":["Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.); Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts zluo@bu.edu hdq0515@163.com","Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.)","Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.); Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts zluo@bu.edu hdq0515@163.com","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I12912129","https://openalex.org/I141649914","https://openalex.org/I9224756"]},{"raw_affiliation_string":"Graduate Program of Clinical Medicine, School of Basic Medical Sciences (H.L, N.-S.L., H.H., Y.Y., Z.L.), Research Institute of Digestive Diseases, and Department of Gastroenterology, the First Affiliated Hospital (L.L., D.H., N.L.)","institution_ids":[]},{"raw_affiliation_string":"Nanchang University, Nanchang, Jiangxi and Graduate Program in Biological Sciences, Northeastern University (S.S.) and Department of Biochemistry, Boston University School of Medicine (H.L., H.H., Y.Y. Z.L.), Boston, Massachusetts","institution_ids":["https://openalex.org/I111088046","https://openalex.org/I12912129","https://openalex.org/I141649914"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3600,"currency":"USD","value_usd":3600},"apc_paid":null,"fwci":2.8587,"has_fulltext":true,"cited_by_count":98,"citation_normalized_percentile":{"value":0.92205,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"88","issue":"6","first_page":"1062","last_page":"1071"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11501","display_name":"TGF-\u03b2 signaling in diseases","score":0.9218999743461609,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11501","display_name":"TGF-\u03b2 signaling in diseases","score":0.9218999743461609,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11339","display_name":"Metabolism, Diabetes, and Cancer","score":0.07530000060796738,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13437","display_name":"Mechanisms of cancer metastasis","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ampk","display_name":"AMPK","score":0.9539999961853027},{"id":"https://openalex.org/keywords/metformin","display_name":"metformin","score":0.890999972820282},{"id":"https://openalex.org/keywords/tgf-beta-signaling","display_name":"TGF-beta signaling","score":0.8870000243186951},{"id":"https://openalex.org/keywords/smad2-3-phosphorylation","display_name":"Smad2/3 phosphorylation","score":0.9980000257492065},{"id":"https://openalex.org/keywords/liver-kinase-b1","display_name":"LKB1","score":0.878000020980835},{"id":"https://openalex.org/keywords/epithelial-mesenchymal-transition","display_name":"epithelial-mesenchymal transition","score":0.9950000047683716},{"id":"https://openalex.org/keywords/tumor-cell-migration","display_name":"tumor cell migration","score":0.996999979019165},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.7300000190734863},{"id":"https://openalex.org/keywords/ampkalpha1","display_name":"AMPK\u03b11","score":0.7559999823570251},{"id":"https://openalex.org/keywords/plasminogen-activator-inhibitor-1","display_name":"plasminogen activator inhibitor-1","score":0.8870000243186951},{"id":"https://openalex.org/keywords/fibronectin","display_name":"fibronectin","score":0.9110000133514404},{"id":"https://openalex.org/keywords/connective-tissue-growth-factor","display_name":"connective tissue growth factor","score":1.0},{"id":"https://openalex.org/keywords/interleukin-6","display_name":"interleukin-6","score":0.9760000109672546},{"id":"https://openalex.org/keywords/phenformin","display_name":"phenformin","score":0.7929999828338623},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.6060000061988831}],"concepts":[{"id":"https://openalex.org/C2780124434","wikidata":"https://www.wikidata.org/wiki/Q12357464","display_name":"AMPK","level":4,"score":0.8301008939743042},{"id":"https://openalex.org/C2778877718","wikidata":"https://www.wikidata.org/wiki/Q753100","display_name":"Phenformin","level":4,"score":0.7664602994918823},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5821298956871033},{"id":"https://openalex.org/C76419328","wikidata":"https://www.wikidata.org/wiki/Q74419","display_name":"Epithelial\u2013mesenchymal transition","level":4,"score":0.5374472737312317},{"id":"https://openalex.org/C97029542","wikidata":"https://www.wikidata.org/wiki/Q281417","display_name":"Protein kinase A","level":3,"score":0.5199933648109436},{"id":"https://openalex.org/C2780323712","wikidata":"https://www.wikidata.org/wiki/Q19484","display_name":"Metformin","level":3,"score":0.5087280869483948},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4826551079750061},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.47173988819122314},{"id":"https://openalex.org/C118131993","wikidata":"https://www.wikidata.org/wiki/Q423671","display_name":"Transforming growth factor","level":2,"score":0.46479979157447815},{"id":"https://openalex.org/C2778229498","wikidata":"https://www.wikidata.org/wiki/Q24785672","display_name":"Transforming growth factor beta","level":3,"score":0.44708141684532166},{"id":"https://openalex.org/C2780631158","wikidata":"https://www.wikidata.org/wiki/Q14907752","display_name":"CTGF","level":4,"score":0.42690175771713257},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.42624300718307495},{"id":"https://openalex.org/C2776780712","wikidata":"https://www.wikidata.org/wiki/Q295240","display_name":"AMP-activated protein kinase","level":5,"score":0.4231637716293335},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3824986517429352},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.3556579649448395},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.29829269647598267},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2971842288970947},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.2968893349170685},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.24436986446380615},{"id":"https://openalex.org/C2775960820","wikidata":"https://www.wikidata.org/wiki/Q408378","display_name":"Growth factor","level":3,"score":0.20407748222351074},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1339871883392334},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.06839552521705627},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.06386500597000122},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010766","descriptor_name":"Phosphorylation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D010766","descriptor_name":"Phosphorylation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D016212","descriptor_name":"Transforming Growth Factor beta","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D016212","descriptor_name":"Transforming Growth Factor beta","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051899","descriptor_name":"Smad2 Protein","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D051899","descriptor_name":"Smad2 Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051900","descriptor_name":"Smad3 Protein","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D051900","descriptor_name":"Smad3 Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D055372","descriptor_name":"AMP-Activated Protein Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D058750","descriptor_name":"Epithelial-Mesenchymal Transition","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D058750","descriptor_name":"Epithelial-Mesenchymal Transition","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1124/mol.115.099549","doi":"https://doi.org/10.1124/mol.115.099549","is_oa":true,"landing_page_url":"https://doi.org/10.1124/mol.115.099549","pdf_url":"https://molpharm.aspetjournals.org/content/molpharm/88/6/1062.full.pdf","source":{"id":"https://openalex.org/S62949411","display_name":"Molecular Pharmacology","issn_l":"0026-895X","issn":["0026-895X","1521-0111"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316283","host_organization_name":"American Society for Pharmacology and Experimental Therapeutics","host_organization_lineage":["https://openalex.org/P4310316283"],"host_organization_lineage_names":["American Society for Pharmacology and Experimental Therapeutics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Pharmacology","raw_type":"journal-article"},{"id":"pmid:26424816","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26424816","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular pharmacology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4658597","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4658597/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Pharmacol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1124/mol.115.099549","doi":"https://doi.org/10.1124/mol.115.099549","is_oa":true,"landing_page_url":"https://doi.org/10.1124/mol.115.099549","pdf_url":"https://molpharm.aspetjournals.org/content/molpharm/88/6/1062.full.pdf","source":{"id":"https://openalex.org/S62949411","display_name":"Molecular Pharmacology","issn_l":"0026-895X","issn":["0026-895X","1521-0111"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316283","host_organization_name":"American Society for Pharmacology and Experimental Therapeutics","host_organization_lineage":["https://openalex.org/P4310316283"],"host_organization_lineage_names":["American Society for Pharmacology and Experimental Therapeutics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Pharmacology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2004210869","display_name":null,"funder_award_id":"31460304","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5054179607","display_name":null,"funder_award_id":"81460374","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G636600238","display_name":"LITAF\u7684\u80bf\u7624\u6291\u5236\u4f5c\u7528","funder_award_id":"81171952","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6848885284","display_name":null,"funder_award_id":"81272926","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7194435696","display_name":"AMPK regulates angiogenesis by inhibition of the ALK1 signaling pathway","funder_award_id":"R21EY024388","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322792","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2195370592.pdf","grobid_xml":"https://content.openalex.org/works/W2195370592.grobid-xml"},"referenced_works_count":56,"referenced_works":["https://openalex.org/W200635154","https://openalex.org/W1505978562","https://openalex.org/W1760215417","https://openalex.org/W1918990441","https://openalex.org/W1970195787","https://openalex.org/W1978690582","https://openalex.org/W1982547932","https://openalex.org/W1986471913","https://openalex.org/W1986834354","https://openalex.org/W1991085635","https://openalex.org/W1995069275","https://openalex.org/W1998912122","https://openalex.org/W2001832472","https://openalex.org/W2009407308","https://openalex.org/W2012106528","https://openalex.org/W2019710745","https://openalex.org/W2022474551","https://openalex.org/W2026967508","https://openalex.org/W2028593825","https://openalex.org/W2037177985","https://openalex.org/W2039152216","https://openalex.org/W2040605398","https://openalex.org/W2043376395","https://openalex.org/W2044874695","https://openalex.org/W2049102197","https://openalex.org/W2061059838","https://openalex.org/W2063699543","https://openalex.org/W2066419333","https://openalex.org/W2071975518","https://openalex.org/W2078767636","https://openalex.org/W2082866035","https://openalex.org/W2090836265","https://openalex.org/W2096662041","https://openalex.org/W2105665055","https://openalex.org/W2107261560","https://openalex.org/W2114408324","https://openalex.org/W2117748926","https://openalex.org/W2119584041","https://openalex.org/W2122855514","https://openalex.org/W2133916339","https://openalex.org/W2134345362","https://openalex.org/W2136887307","https://openalex.org/W2138226825","https://openalex.org/W2142686308","https://openalex.org/W2144144349","https://openalex.org/W2150563600","https://openalex.org/W2154024784","https://openalex.org/W2155598285","https://openalex.org/W2156323704","https://openalex.org/W2165190419","https://openalex.org/W2168471697","https://openalex.org/W2169520827","https://openalex.org/W2170095317","https://openalex.org/W2171998898","https://openalex.org/W4253422011","https://openalex.org/W6640071169"],"related_works":["https://openalex.org/W2276308812","https://openalex.org/W3129164101","https://openalex.org/W2049102197","https://openalex.org/W2549072901","https://openalex.org/W2810462336","https://openalex.org/W2170095317","https://openalex.org/W2807063223","https://openalex.org/W4323257146","https://openalex.org/W2221293297","https://openalex.org/W4254495983"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":11},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":10},{"year":2017,"cited_by_count":10},{"year":2016,"cited_by_count":7}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}
