{"id":"https://openalex.org/W2195366155","doi":"https://doi.org/10.1016/j.devcel.2015.11.014","title":"Liquids, Fibers, and Gels: The Many Phases of Neurodegeneration","display_name":"Liquids, Fibers, and Gels: The Many Phases of Neurodegeneration","publication_year":2015,"publication_date":"2015-12-01","ids":{"openalex":"https://openalex.org/W2195366155","doi":"https://doi.org/10.1016/j.devcel.2015.11.014","mag":"2195366155","pmid":"https://pubmed.ncbi.nlm.nih.gov/26651288"},"language":"en","primary_location":{"id":"doi:10.1016/j.devcel.2015.11.014","doi":"https://doi.org/10.1016/j.devcel.2015.11.014","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.devcel.2015.11.014","pdf_url":"http://www.cell.com/article/S1534580715007492/pdf","source":{"id":"https://openalex.org/S83804233","display_name":"Developmental Cell","issn_l":"1534-5807","issn":["1534-5807","1878-1551"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Cell","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.cell.com/article/S1534580715007492/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055503247","display_name":"Shana Elbaum\u2010Garfinkle","orcid":"https://orcid.org/0000-0002-3953-7329","observed_orcids":["https://orcid.org/0000-0002-3953-7329"]},"institutions":[{"id":"https://openalex.org/I20089843","display_name":"Princeton University","ror":"https://ror.org/00hx57361","country_code":"US","type":"education","lineage":["https://openalex.org/I20089843"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shana Elbaum-Garfinkle","raw_affiliation_strings":["Department of Chemical and Biological Engineering, Princeton University, Princeton, NJ 08544, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical and Biological Engineering, Princeton University, Princeton, NJ 08544, USA","institution_ids":["https://openalex.org/I20089843"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042735526","display_name":"Clifford P. Brangwynne","orcid":"https://orcid.org/0000-0002-1350-9960","observed_orcids":["https://orcid.org/0000-0002-1350-9960"]},"institutions":[{"id":"https://openalex.org/I20089843","display_name":"Princeton University","ror":"https://ror.org/00hx57361","country_code":"US","type":"education","lineage":["https://openalex.org/I20089843"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Clifford\u00a0P. Brangwynne","raw_affiliation_strings":["Department of Chemical and Biological Engineering, Princeton University, Princeton, NJ 08544, USA. Electronic address: cbrangwy@princeton.edu","Department of Chemical and Biological Engineering, Princeton University, Princeton, NJ 08544, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical and Biological Engineering, Princeton University, Princeton, NJ 08544, USA. Electronic address: cbrangwy@princeton.edu","institution_ids":["https://openalex.org/I20089843"]},{"raw_affiliation_string":"Department of Chemical and Biological Engineering, Princeton University, Princeton, NJ 08544, USA","institution_ids":["https://openalex.org/I20089843"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5042735526"],"corresponding_institution_ids":["https://openalex.org/I20089843"],"apc_list":{"value":10400,"currency":"USD","value_usd":10400},"apc_paid":null,"fwci":4.4583,"has_fulltext":false,"cited_by_count":59,"citation_normalized_percentile":{"value":0.94471119,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"35","issue":"5","first_page":"531","last_page":"532"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":0.9487000107765198,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":0.9487000107765198,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.017000000923871994,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.014800000004470348,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neurodegeneration","display_name":"neurodegeneration","score":0.8289999961853027},{"id":"https://openalex.org/keywords/protein-phase-transitions","display_name":"protein phase transitions","score":0.7419999837875366},{"id":"https://openalex.org/keywords/liquid-liquid-phase-separation","display_name":"liquid-liquid phase separation","score":0.8069999814033508},{"id":"https://openalex.org/keywords/protein-gels","display_name":"protein gels","score":0.6420000195503235},{"id":"https://openalex.org/keywords/fus-mutations","display_name":"FUS mutations","score":0.8510000109672546},{"id":"https://openalex.org/keywords/amyotrophic-lateral-sclerosis","display_name":"amyotrophic lateral sclerosis","score":0.996999979019165},{"id":"https://openalex.org/keywords/neurotoxicity","display_name":"neurotoxicity","score":0.9150000214576721},{"id":"https://openalex.org/keywords/caenorhabditis-elegans","display_name":"Caenorhabditis elegans","score":0.9079999923706055}],"concepts":[{"id":"https://openalex.org/C2776925932","wikidata":"https://www.wikidata.org/wiki/Q1755122","display_name":"Neurodegeneration","level":3,"score":0.8610008358955383},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7505803108215332},{"id":"https://openalex.org/C2779491297","wikidata":"https://www.wikidata.org/wiki/Q3338704","display_name":"Neurotoxicity","level":3,"score":0.7079213857650757},{"id":"https://openalex.org/C108586683","wikidata":"https://www.wikidata.org/wiki/Q17164826","display_name":"Self-healing hydrogels","level":2,"score":0.4815950095653534},{"id":"https://openalex.org/C2778794669","wikidata":"https://www.wikidata.org/wiki/Q43054","display_name":"Neuron","level":2,"score":0.47948798537254333},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.448709100484848},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.44594940543174744},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.4102684259414673},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3610520660877228},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3325497508049011},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.12906277179718018},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.10287651419639587},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.08795318007469177},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.07322239875793457},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000690","descriptor_name":"Amyotrophic Lateral Sclerosis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009043","descriptor_name":"Motor Activity","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020100","descriptor_name":"Hydrogels","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D029742","descriptor_name":"Caenorhabditis elegans Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D034702","descriptor_name":"RNA-Binding Protein FUS","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D044367","descriptor_name":"Phase Transition","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057174","descriptor_name":"Frontotemporal Lobar Degeneration","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.devcel.2015.11.014","doi":"https://doi.org/10.1016/j.devcel.2015.11.014","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.devcel.2015.11.014","pdf_url":"http://www.cell.com/article/S1534580715007492/pdf","source":{"id":"https://openalex.org/S83804233","display_name":"Developmental Cell","issn_l":"1534-5807","issn":["1534-5807","1878-1551"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Cell","raw_type":"journal-article"},{"id":"pmid:26651288","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26651288","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental cell","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.devcel.2015.11.014","doi":"https://doi.org/10.1016/j.devcel.2015.11.014","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.devcel.2015.11.014","pdf_url":"http://www.cell.com/article/S1534580715007492/pdf","source":{"id":"https://openalex.org/S83804233","display_name":"Developmental Cell","issn_l":"1534-5807","issn":["1534-5807","1878-1551"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Cell","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8371999859809875,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2195366155.pdf"},"referenced_works_count":10,"referenced_works":["https://openalex.org/W1854281301","https://openalex.org/W1938908576","https://openalex.org/W1952608303","https://openalex.org/W2100383597","https://openalex.org/W2102898524","https://openalex.org/W2111796925","https://openalex.org/W2150860983","https://openalex.org/W2168639701","https://openalex.org/W2168958678","https://openalex.org/W2271817176"],"related_works":["https://openalex.org/W1952608303","https://openalex.org/W2168958678","https://openalex.org/W7211959353","https://openalex.org/W4385618104","https://openalex.org/W2800004384","https://openalex.org/W7223315815","https://openalex.org/W3128587423","https://openalex.org/W2934039982","https://openalex.org/W7167334766","https://openalex.org/W2600049383"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":8},{"year":2016,"cited_by_count":6}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}