{"id":"https://openalex.org/W2192474532","doi":"https://doi.org/10.1200/jco.2015.33.15_suppl.5059","title":"Tissue-based genomics to augment post-prostatectomy risk stratification in a natural history cohort.","display_name":"Tissue-based genomics to augment post-prostatectomy risk stratification in a natural history cohort.","publication_year":2015,"publication_date":"2015-05-20","ids":{"openalex":"https://openalex.org/W2192474532","doi":"https://doi.org/10.1200/jco.2015.33.15_suppl.5059","mag":"2192474532"},"language":"en","primary_location":{"id":"doi:10.1200/jco.2015.33.15_suppl.5059","doi":"https://doi.org/10.1200/jco.2015.33.15_suppl.5059","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2015.33.15_suppl.5059","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039646183","display_name":"Ashley Evan Ross","orcid":"https://orcid.org/0000-0001-7044-9688","observed_orcids":["https://orcid.org/0000-0001-7044-9688"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ashley Ross","raw_affiliation_strings":["The Johns Hopkins University School of Medicine, Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins University School of Medicine, Baltimore, MD","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049688133","display_name":"Michael Hiroshi Johnson","orcid":"https://orcid.org/0000-0003-4393-2468","observed_orcids":["https://orcid.org/0000-0003-4393-2468"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Hiroshi Johnson","raw_affiliation_strings":["Johns Hopkins Hosp, Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Johns Hopkins Hosp, Baltimore, MD","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076810623","display_name":"Kasra Yousefi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kasra Yousefi","raw_affiliation_strings":["GenomeDx Biosciences, Inc., Vancouver, BC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GenomeDx Biosciences, Inc., Vancouver, BC, Canada","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014582211","display_name":"Elai Davicioni","orcid":"https://orcid.org/0000-0001-9136-099X","observed_orcids":["https://orcid.org/0000-0001-9136-099X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elai Davicioni","raw_affiliation_strings":["GenomeDx Biosciences, Inc., Vancouver, BC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GenomeDx Biosciences, Inc., Vancouver, BC, Canada","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110356860","display_name":"Helen L. Fedor","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Helen L. Fedor","raw_affiliation_strings":["Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000152049","display_name":"Stephanie A. Glavaris","orcid":"https://orcid.org/0000-0002-8695-052X","observed_orcids":["https://orcid.org/0000-0002-8695-052X"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephanie Glavaris","raw_affiliation_strings":["The Johns Hopkins University School of Medicine, Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins University School of Medicine, Baltimore, MD","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089925113","display_name":"Voleak Choeurng","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Voleak Choeurng","raw_affiliation_strings":["GenomeDx Biosciences, Inc., Vancouver, BC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GenomeDx Biosciences, Inc., Vancouver, BC, Canada","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005277533","display_name":"Christine Buerki","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christine Buerki","raw_affiliation_strings":["GenomeDx Biosciences, Inc., Vancouver, BC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GenomeDx Biosciences, Inc., Vancouver, BC, Canada","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033660195","display_name":"Lucia L.C. Lam","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lucia L.C. Lam","raw_affiliation_strings":["GenomeDx Biosciences, Inc., Vancouver, BC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GenomeDx Biosciences, Inc., Vancouver, BC, Canada","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044704274","display_name":"Nicholas Erho","orcid":"https://orcid.org/0000-0002-5857-2701","observed_orcids":["https://orcid.org/0000-0002-5857-2701"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nicholas Erho","raw_affiliation_strings":["GenomeDx Biosciences, Inc., Vancouver, BC, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"GenomeDx Biosciences, Inc., Vancouver, BC, Canada","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085439390","display_name":"Elizabeth B. Humphreys","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elizabeth B. Humphreys","raw_affiliation_strings":["The Johns Hopkins University School of Medicine, Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins University School of Medicine, Baltimore, MD","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064618296","display_name":"George Jabboure Netto","orcid":"https://orcid.org/0000-0003-3915-9134","observed_orcids":["https://orcid.org/0000-0003-3915-9134"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"George J. Netto","raw_affiliation_strings":["The Johns Hopkins Medical Institutions, Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins Medical Institutions, Baltimore, MD","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030178630","display_name":"Misop Han","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Misop Han","raw_affiliation_strings":["The James Buchanan Brady Urological Institute, Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The James Buchanan Brady Urological Institute, Baltimore, MD","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063449536","display_name":"Alan Wayne Partin","orcid":"https://orcid.org/0000-0003-2523-7592","observed_orcids":["https://orcid.org/0000-0003-2523-7592"]},"institutions":[{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alan W. Partin","raw_affiliation_strings":["The Johns Hopkins Hosp, Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins Hosp, Baltimore, MD","institution_ids":["https://openalex.org/I4210150714"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010930816","display_name":"Bruce J. Trock","orcid":"https://orcid.org/0000-0003-3529-9295","observed_orcids":["https://orcid.org/0000-0003-3529-9295"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bruce J. Trock","raw_affiliation_strings":["The Johns Hopkins University, Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins University, Baltimore, MD","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013881851","display_name":"Edward Matthew Schaeffer","orcid":"https://orcid.org/0000-0003-0699-1899","observed_orcids":["https://orcid.org/0000-0003-0699-1899"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Edward M. Schaeffer","raw_affiliation_strings":["The Johns Hopkins University School of Medicine, Baltimore, MD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins University School of Medicine, Baltimore, MD","institution_ids":["https://openalex.org/I145311948"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"33","issue":"15_suppl","first_page":"5059","last_page":"5059"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.42649999260902405,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.42649999260902405,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10543","display_name":"Prostate Cancer Treatment and Research","score":0.3831000030040741,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.14429999887943268,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"prostate cancer","score":0.875},{"id":"https://openalex.org/keywords/radical-prostatectomy","display_name":"radical prostatectomy","score":0.9980000257492065},{"id":"https://openalex.org/keywords/genomic-classifier","display_name":"genomic classifier","score":0.4860000014305115},{"id":"https://openalex.org/keywords/gene-expression-signatures","display_name":"gene expression signatures","score":0.6819999814033508},{"id":"https://openalex.org/keywords/metastasis-risk-stratification","display_name":"metastasis risk stratification","score":0.843999981880188},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.9160000085830688},{"id":"https://openalex.org/keywords/metastasis-free-survival","display_name":"metastasis-free survival","score":0.8450000286102295},{"id":"https://openalex.org/keywords/intermediate-and-high-risk-prostate-cancer","display_name":"intermediate- and high-risk prostate cancer","score":0.609000027179718},{"id":"https://openalex.org/keywords/capra-s-score","display_name":"CAPRA-S score","score":0.6850000023841858},{"id":"https://openalex.org/keywords/natural-history-cohort","display_name":"natural history cohort","score":0.6349999904632568}],"concepts":[{"id":"https://openalex.org/C2779070825","wikidata":"https://www.wikidata.org/wiki/Q760434","display_name":"Augment","level":2,"score":0.8869279623031616},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8118561506271362},{"id":"https://openalex.org/C163276114","wikidata":"https://www.wikidata.org/wiki/Q484591","display_name":"Natural history","level":2,"score":0.7575664520263672},{"id":"https://openalex.org/C3020404979","wikidata":"https://www.wikidata.org/wiki/Q1058438","display_name":"Risk stratification","level":2,"score":0.6987736225128174},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.586919903755188},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.4578801989555359},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.45399317145347595},{"id":"https://openalex.org/C192943249","wikidata":"https://www.wikidata.org/wiki/Q1893382","display_name":"Stratification (seeds)","level":5,"score":0.4530602693557739},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4275187849998474},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4002602696418762},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.22158929705619812},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.20551735162734985},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.16296261548995972},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.13852116465568542},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13226893544197083},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C88548481","wikidata":"https://www.wikidata.org/wiki/Q2397491","display_name":"Seed dormancy","level":4,"score":0.0},{"id":"https://openalex.org/C3527866","wikidata":"https://www.wikidata.org/wiki/Q162267","display_name":"Dormancy","level":3,"score":0.0},{"id":"https://openalex.org/C100701293","wikidata":"https://www.wikidata.org/wiki/Q193838","display_name":"Germination","level":2,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1200/jco.2015.33.15_suppl.5059","doi":"https://doi.org/10.1200/jco.2015.33.15_suppl.5059","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2015.33.15_suppl.5059","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1998343146","https://openalex.org/W3135147882","https://openalex.org/W1508662657","https://openalex.org/W2042984497","https://openalex.org/W2257053422","https://openalex.org/W2590818354","https://openalex.org/W2012073236","https://openalex.org/W2775397021","https://openalex.org/W4324136965","https://openalex.org/W2965677442"],"abstract_inverted_index":{"5059":[0],"Background:":[1],"Genomics":[2],"has":[3],"provided":[4,171,329],"insight":[5],"into":[6],"the":[7,16,77,172,278,290,293],"underpinnings":[8],"of":[9,21,41,79,123,136,144,187,222,246,265,292,312,332],"lethal":[10],"prostate":[11],"cancer":[12],"and":[13,18,64,71,89,98,121,168,198,208,302,325],"led":[14],"to":[15,60,100,175,257],"development":[17],"clinical":[19],"use":[20],"RNA":[22,94,129],"expression":[23,31,108,266,282,297,318],"based":[24,156],"gene":[25,150],"signatures.":[26,334],"We":[27],"performed":[28],"genome":[29],"wide":[30],"profiling":[32],"on":[33,157,224],"tissue":[34],"from":[35,106,132,268,277],"a":[36,57,140,308],"large":[37],"natural":[38,309],"history":[39,310],"cohort":[40,311],"at":[42,180,211],"risk":[43,66,237],"men":[44,67,134,190,242,313],"undergoing":[45,314],"radical":[46],"prostatectomy":[47],"(RP).":[48],"Methods:":[49],"In":[50],"an":[51],"IRB":[52],"approved":[53],"study,":[54],"we":[55],"utilized":[56],"case-cohort":[58],"design":[59],"identify":[61],"356":[62],"intermediate":[63,196,236],"high":[65,199,262],"who":[68],"underwent":[69],"RP":[70,81],"had":[72,322],"no":[73],"further":[74],"treatment":[75],"until":[76],"time":[78],"metastasis.":[80],"specimens":[82],"were":[83,92,110,152],"regraded":[84],"by":[85,228],"2005":[86],"ISUP":[87],"criteria":[88],"index":[90],"lesions":[91],"sampled.":[93],"was":[95,130,205,219,230],"prepared,":[96],"labelled":[97],"hybridized":[99],"Human":[101],"Exon":[102],"1.0":[103],"ST":[104],"microarrays":[105],"which":[107],"signatures":[109,151,267,298,319],"analyzed.":[111],"The":[112],"study":[113],"followed":[114],"REMARK":[115],"guidelines":[116],"for":[117],"prospective":[118],"blinded":[119],"evaluation":[120],"analysis":[122,331],"prognostic":[124,221,305,327],"biomarkers.":[125],"Results:":[126],"Microarray":[127],"quality":[128],"obtained":[131],"260":[133],"(99":[135],"whom":[137],"metastasized)":[138],"with":[139,191,243,249,261],"median":[141],"follow":[142],"up":[143],"9":[145],"years":[146,182,213],"(IQR":[147],"6-12).":[148],"34":[149,317],"evaluated,":[153],"including":[154],"3":[155],"commercially":[158],"available":[159],"assays":[160],"(genomic":[161],"classifier":[162],"[GC,":[163],"Decipher],":[164],"microarray":[165],"derived":[166],"[md]-CCP,":[167],"md-GPS).":[169],"GC":[170,203,218,229,251,321],"highest":[173],"c-index":[174,285],"predict":[176],"metastasis":[177,188,223,255],"free":[178],"survival":[179],"10":[181],"post-RP":[183,214],"(0.76).":[184],"Cumulative":[185],"incidence":[186],"among":[189,233,241,259],"low":[192,250],"(":[193,200],"<":[194,216],"0.45),":[195],"(0.45-0.6)":[197],">":[201],"0.6)":[202],"scores":[204,252],"12,":[206],"31":[207],"47%":[209],"respectively":[210],"5":[212],"(p":[215],"0.001).":[217],"independently":[220],"multivariable":[225],"analysis.":[226],"Stratification":[227],"most":[231],"notable":[232],"nomogram":[234],"predicted":[235],"men.":[238],"For":[239],"instance,":[240],"CAPRA-S":[244],"score":[245],"3-5,":[247],"10%":[248],"would":[253],"develop":[254],"compared":[256],"27%":[258],"those":[260],"scores.":[263],"Addition":[264],"other":[269,333],"CLIA":[270],"certified":[271],"tests":[272],"(md-CCP":[273],"or":[274,276],"md-GPS)":[275],"next":[279],"best":[280],"performing":[281],"signature":[283],"(md-Penney,":[284],"0.74)":[286],"did":[287],"not":[288],"improve":[289],"performance":[291,324],"GC.":[294],"Conclusions:":[295],"Genomic":[296],"stratify":[299],"metastatic":[300],"outcomes":[301],"provide":[303],"additional":[304],"information":[306,328],"in":[307],"RP.":[315],"Of":[316],"analyzed,":[320],"optimal":[323],"captured":[326],"via":[330]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2016-06-24T00:00:00"}