{"id":"https://openalex.org/W2191601048","doi":"https://doi.org/10.1016/b978-0-08-029775-0.50085-7","title":"Lipoxygenase Products of Arachidonic Acid: their Role in Inflammatory Events Mediated by Human Basophils and Mast Cells","display_name":"Lipoxygenase Products of Arachidonic Acid: their Role in Inflammatory Events Mediated by Human Basophils and Mast Cells","publication_year":1983,"publication_date":"1983-01-01","ids":{"openalex":"https://openalex.org/W2191601048","doi":"https://doi.org/10.1016/b978-0-08-029775-0.50085-7","mag":"2191601048"},"language":"en","primary_location":{"id":"doi:10.1016/b978-0-08-029775-0.50085-7","doi":"https://doi.org/10.1016/b978-0-08-029775-0.50085-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-08-029775-0.50085-7","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Immunopharmacology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W6903035034","display_name":"Advances in Immunopharmacology"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047213494","display_name":"Stephen P. Peters","orcid":"https://orcid.org/0000-0003-4176-7999","observed_orcids":["https://orcid.org/0000-0003-4176-7999"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S.P. PETERS","raw_affiliation_strings":["The Johns Hopkins University School of Medicine, Department of Medicine, Divisions of Clinical immunology and Respiratory Medicine, at The Good Samaritan Hospital, 5601 Loch Raven Boulevard, Baltimore, MD 21239, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins University School of Medicine, Department of Medicine, Divisions of Clinical immunology and Respiratory Medicine, at The Good Samaritan Hospital, 5601 Loch Raven Boulevard, Baltimore, MD 21239, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056666751","display_name":"Robert P. Schleimer","orcid":"https://orcid.org/0000-0002-8330-0097","observed_orcids":["https://orcid.org/0000-0002-8330-0097"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R.P. SCHLEIMER","raw_affiliation_strings":["The Johns Hopkins University School of Medicine, Department of Medicine, Divisions of Clinical immunology and Respiratory Medicine, at The Good Samaritan Hospital, 5601 Loch Raven Boulevard, Baltimore, MD 21239, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins University School of Medicine, Department of Medicine, Divisions of Clinical immunology and Respiratory Medicine, at The Good Samaritan Hospital, 5601 Loch Raven Boulevard, Baltimore, MD 21239, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081046119","display_name":"Donald W. MacGlashan","orcid":"https://orcid.org/0000-0003-4525-0452","observed_orcids":["https://orcid.org/0000-0003-4525-0452"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D.W. MacGLASHAN","raw_affiliation_strings":["The Johns Hopkins University School of Medicine, Department of Medicine, Divisions of Clinical immunology and Respiratory Medicine, at The Good Samaritan Hospital, 5601 Loch Raven Boulevard, Baltimore, MD 21239, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins University School of Medicine, Department of Medicine, Divisions of Clinical immunology and Respiratory Medicine, at The Good Samaritan Hospital, 5601 Loch Raven Boulevard, Baltimore, MD 21239, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065558462","display_name":"Edward S. Schulman","orcid":"https://orcid.org/0000-0003-2928-2665","observed_orcids":["https://orcid.org/0000-0003-2928-2665"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E.S. SCHULMAN","raw_affiliation_strings":["The Johns Hopkins University School of Medicine, Department of Medicine, Divisions of Clinical immunology and Respiratory Medicine, at The Good Samaritan Hospital, 5601 Loch Raven Boulevard, Baltimore, MD 21239, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins University School of Medicine, Department of Medicine, Divisions of Clinical immunology and Respiratory Medicine, at The Good Samaritan Hospital, 5601 Loch Raven Boulevard, Baltimore, MD 21239, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067592962","display_name":"Anne Kagey\u2010Sobotka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. KAGEY-SOBOTKA","raw_affiliation_strings":["The Johns Hopkins University School of Medicine, Department of Medicine, Divisions of Clinical immunology and Respiratory Medicine, at The Good Samaritan Hospital, 5601 Loch Raven Boulevard, Baltimore, MD 21239, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins University School of Medicine, Department of Medicine, Divisions of Clinical immunology and Respiratory Medicine, at The Good Samaritan Hospital, 5601 Loch Raven Boulevard, Baltimore, MD 21239, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112066790","display_name":"G. Kenneth Adams","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G.K. ADAMS","raw_affiliation_strings":["The Johns Hopkins University School of Medicine, Department of Medicine, Divisions of Clinical immunology and Respiratory Medicine, at The Good Samaritan Hospital, 5601 Loch Raven Boulevard, Baltimore, MD 21239, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins University School of Medicine, Department of Medicine, Divisions of Clinical immunology and Respiratory Medicine, at The Good Samaritan Hospital, 5601 Loch Raven Boulevard, Baltimore, MD 21239, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110859557","display_name":"L.M. Lichtenstein","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I2799853436","display_name":"Johns Hopkins Medicine","ror":"https://ror.org/037zgn354","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L.M. LICHTENSTEIN","raw_affiliation_strings":["The Johns Hopkins University School of Medicine, Department of Medicine, Divisions of Clinical immunology and Respiratory Medicine, at The Good Samaritan Hospital, 5601 Loch Raven Boulevard, Baltimore, MD 21239, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Johns Hopkins University School of Medicine, Department of Medicine, Divisions of Clinical immunology and Respiratory Medicine, at The Good Samaritan Hospital, 5601 Loch Raven Boulevard, Baltimore, MD 21239, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I2799853436"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.30651872,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"617","last_page":"622"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.9434000253677368,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.9434000253677368,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.026100000366568565,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12910","display_name":"Eicosanoids and Hypertension Pharmacology","score":0.007799999788403511,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lipoxygenase-products","display_name":"lipoxygenase products","score":0.9549999833106995},{"id":"https://openalex.org/keywords/arachidonic-acid","display_name":"arachidonic acid","score":0.9350000023841858},{"id":"https://openalex.org/keywords/basophils","display_name":"basophils","score":0.8700000047683716},{"id":"https://openalex.org/keywords/mast-cells","display_name":"mast cells","score":0.8600000143051147},{"id":"https://openalex.org/keywords/allergic-inflammation","display_name":"allergic inflammation","score":0.6840000152587891},{"id":"https://openalex.org/keywords/inflammatory-mediators","display_name":"inflammatory mediators","score":0.871999979019165},{"id":"https://openalex.org/keywords/mediator-release","display_name":"mediator release","score":0.8840000033378601},{"id":"https://openalex.org/keywords/pulmonary-mast-cells","display_name":"pulmonary mast cells","score":0.7229999899864197},{"id":"https://openalex.org/keywords/cell-activation","display_name":"cell activation","score":0.45899999141693115}],"concepts":[{"id":"https://openalex.org/C2780857362","wikidata":"https://www.wikidata.org/wiki/Q1827455","display_name":"Lipoxygenase","level":3,"score":0.8034168481826782},{"id":"https://openalex.org/C2778078955","wikidata":"https://www.wikidata.org/wiki/Q407699","display_name":"Arachidonic acid","level":3,"score":0.7117074728012085},{"id":"https://openalex.org/C2779726688","wikidata":"https://www.wikidata.org/wiki/Q191989","display_name":"Mast cell","level":2,"score":0.6163325309753418},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5929515957832336},{"id":"https://openalex.org/C141105273","wikidata":"https://www.wikidata.org/wiki/Q79455","display_name":"Immunoglobulin E","level":3,"score":0.5718097686767578},{"id":"https://openalex.org/C90342290","wikidata":"https://www.wikidata.org/wiki/Q94234745","display_name":"Arachidonate 5-lipoxygenase","level":4,"score":0.5572175979614258},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.4650007486343384},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.435091495513916},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.42301011085510254},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.3872557580471039},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.37496525049209595},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.29259294271469116},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23585712909698486},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.09922757744789124}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/b978-0-08-029775-0.50085-7","doi":"https://doi.org/10.1016/b978-0-08-029775-0.50085-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-08-029775-0.50085-7","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Immunopharmacology","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1528190130","https://openalex.org/W1577486091","https://openalex.org/W1896640126","https://openalex.org/W1990747805","https://openalex.org/W2010729010","https://openalex.org/W2011793087","https://openalex.org/W2023213942","https://openalex.org/W2033110553","https://openalex.org/W2064186229","https://openalex.org/W2088435132","https://openalex.org/W2090334210","https://openalex.org/W2091780008","https://openalex.org/W2123773797","https://openalex.org/W2132211952","https://openalex.org/W2281179837"],"related_works":["https://openalex.org/W1968625436","https://openalex.org/W2417058367","https://openalex.org/W2033269144","https://openalex.org/W2480666188","https://openalex.org/W2092446496","https://openalex.org/W2147409179","https://openalex.org/W2410249044","https://openalex.org/W153197441","https://openalex.org/W156068408","https://openalex.org/W2033110553"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
