{"id":"https://openalex.org/W2189990240","doi":null,"title":"Transnasal butorphanol for pain relief after uvulopalatopharyngoplasty - a hospital-based,randomized study.","display_name":"Transnasal butorphanol for pain relief after uvulopalatopharyngoplasty - a hospital-based,randomized study.","publication_year":2009,"publication_date":"2009-07-01","ids":{"openalex":"https://openalex.org/W2189990240","mag":"2189990240","pmid":"https://pubmed.ncbi.nlm.nih.gov/19664345"},"language":"en","primary_location":{"id":"pmid:19664345","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19664345","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chang Gung medical journal","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102301783","display_name":"Hao-Chun Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I173093425","display_name":"Chang Gung University","ror":"https://ror.org/00d80zx46","country_code":"TW","type":"education","lineage":["https://openalex.org/I173093425"]},{"id":"https://openalex.org/I3020100970","display_name":"Chang Gung Memorial Hospital","ror":"https://ror.org/02verss31","country_code":"TW","type":"healthcare","lineage":["https://openalex.org/I3020100970"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Hao-Chun Huang","raw_affiliation_strings":["Department of Otolaryngology, Chang Gung Memorial Hospital, Taipei, Chang Gung University College of Medicine, Taoyuan, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otolaryngology, Chang Gung Memorial Hospital, Taipei, Chang Gung University College of Medicine, Taoyuan, Taiwan","institution_ids":["https://openalex.org/I173093425","https://openalex.org/I3020100970"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064348942","display_name":"Li\u2010Ang Lee","orcid":"https://orcid.org/0000-0001-8414-595X","observed_orcids":["https://orcid.org/0000-0001-8414-595X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Li-Ang Lee","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091165194","display_name":"Tuan\u2010Jen Fang","orcid":"https://orcid.org/0000-0002-7805-3458","observed_orcids":["https://orcid.org/0000-0002-7805-3458","https://orcid.org/0000-0002-8762-3635"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tuan-Jen Fang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062560431","display_name":"Hsueh\u2010Yu Li","orcid":"https://orcid.org/0000-0002-9016-8098","observed_orcids":["https://orcid.org/0000-0002-9016-8098","https://orcid.org/0000-0003-2224-093X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hsueh-Yu Li","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003094698","display_name":"Ching\u2010Chia Lo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ching-Chia Lo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5046481278","display_name":"Jo\u2010Hsuan Wu","orcid":"https://orcid.org/0000-0002-9435-746X","observed_orcids":["https://orcid.org/0000-0002-9435-746X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jo-Hsuan Wu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3616,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.65270957,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"32","issue":"4","first_page":"390","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10189","display_name":"Anesthesia and Pain Management","score":0.9487000107765198,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10189","display_name":"Anesthesia and Pain Management","score":0.9487000107765198,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11199","display_name":"Pain Management and Opioid Use","score":0.030500000342726707,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research","score":0.01119999960064888,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/uvulopalatopharyngoplasty","display_name":"uvulopalatopharyngoplasty","score":0.9950000047683716},{"id":"https://openalex.org/keywords/obstructive-sleep-apnea","display_name":"obstructive sleep apnea","score":0.9110000133514404},{"id":"https://openalex.org/keywords/postoperative-pain","display_name":"postoperative pain","score":0.9610000252723694},{"id":"https://openalex.org/keywords/oropharyngeal-pain","display_name":"oropharyngeal pain","score":0.9200000166893005},{"id":"https://openalex.org/keywords/mefenamic-acid","display_name":"mefenamic acid","score":0.8019999861717224},{"id":"https://openalex.org/keywords/meperidine","display_name":"pethidine","score":0.9779999852180481}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9823178648948669},{"id":"https://openalex.org/C2779761351","wikidata":"https://www.wikidata.org/wiki/Q3047612","display_name":"Uvulopalatopharyngoplasty","level":4,"score":0.8152078986167908},{"id":"https://openalex.org/C14184104","wikidata":"https://www.wikidata.org/wiki/Q1362526","display_name":"Visual analogue scale","level":2,"score":0.7553174495697021},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.7064513564109802},{"id":"https://openalex.org/C2781020239","wikidata":"https://www.wikidata.org/wiki/Q1185089","display_name":"Butorphanol","level":2,"score":0.6821469068527222},{"id":"https://openalex.org/C2780820201","wikidata":"https://www.wikidata.org/wiki/Q173235","display_name":"Analgesic","level":2,"score":0.4865368902683258},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.47309187054634094},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.4665527045726776},{"id":"https://openalex.org/C2776006263","wikidata":"https://www.wikidata.org/wiki/Q16606552","display_name":"Obstructive sleep apnea","level":2,"score":0.4164336621761322},{"id":"https://openalex.org/C2781326671","wikidata":"https://www.wikidata.org/wiki/Q754424","display_name":"Apnea","level":2,"score":0.33993417024612427},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.32192322611808777},{"id":"https://openalex.org/C2778205975","wikidata":"https://www.wikidata.org/wiki/Q1754874","display_name":"Polysomnography","level":3,"score":0.2092704474925995},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.10458552837371826}],"mesh":[{"descriptor_ui":"D000281","descriptor_name":"Administration, Intranasal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002077","descriptor_name":"Butorphanol","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D002077","descriptor_name":"Butorphanol","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008528","descriptor_name":"Mefenamic Acid","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D008614","descriptor_name":"Meperidine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010147","descriptor_name":"Pain Measurement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010149","descriptor_name":"Postoperative Pain","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D010160","descriptor_name":"Palate, Soft","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D010614","descriptor_name":"Pharynx","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014609","descriptor_name":"Uvula","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D020181","descriptor_name":"Sleep Apnea, Obstructive","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true}],"locations_count":3,"locations":[{"id":"pmid:19664345","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19664345","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chang Gung medical journal","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.511.8623","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.511.8623","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://memo.cgu.edu.tw/cgmj/3204/320405.pdf","raw_type":"text"},{"id":"mag:2189990240","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19664345","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W651414284","https://openalex.org/W1963710671","https://openalex.org/W1963822485","https://openalex.org/W1967073951","https://openalex.org/W1995189949","https://openalex.org/W2004358122","https://openalex.org/W2010824248","https://openalex.org/W2020723984","https://openalex.org/W2024286088","https://openalex.org/W2058905056","https://openalex.org/W2063316498","https://openalex.org/W2135851538","https://openalex.org/W2151280731","https://openalex.org/W2154932696","https://openalex.org/W2159158789","https://openalex.org/W2170690772","https://openalex.org/W2341497390","https://openalex.org/W2402964451"],"related_works":["https://openalex.org/W7096550080","https://openalex.org/W1995189949","https://openalex.org/W1530928809","https://openalex.org/W1963822485","https://openalex.org/W7213307860","https://openalex.org/W2471727045","https://openalex.org/W2254848945","https://openalex.org/W2153386656","https://openalex.org/W2349504212","https://openalex.org/W1966900371"],"abstract_inverted_index":{"BACKGROUND:":[0],"Nasal":[1],"spray":[2],"of":[3,20,138,171,204,224,243],"analgesic":[4],"is":[5],"a":[6,61,110],"novel":[7],"administration":[8],"for":[9,24],"postoperative":[10],"pain":[11,25,38,77,106,132,142,154,205,231],"control.":[12],"In":[13],"this":[14],"study,":[15],"we":[16],"assessed":[17],"the":[18,113,124,168,191,202,210,229,241],"efficacy":[19],"transnasal":[21],"butorphanol":[22],"(TB)":[23],"relief":[26,206],"following":[27],"uvulopalatopharyngoplasty":[28],"(UPPP)":[29],"in":[30,60,117,140,190,201,234,245],"obstructive":[31],"sleep":[32,64],"apnea":[33],"(OSA)":[34],"patients,":[35],"and":[36,45,72,100,112,120,127,136,185,220],"compared":[37],"alleviation":[39],"effect":[40],"to":[41,94],"oral":[42],"mefenamic":[43],"acid":[44],"intramuscular":[46],"meperidine":[47],"(M>":[48],"or":[49,84],"=&M).":[50],"METHODS:":[51],"A":[52],"prospective,":[53],"randomized,":[54],"open":[55],"label":[56],"study":[57,238],"was":[58,107,207],"conducted":[59],"tertiary":[62],"care":[63],"center.":[65],"Twelve":[66],"OSA":[67,235],"patients":[68,246],"with":[69],"full":[70],"consciousness":[71],"at":[73,123],"least":[74],"moderate":[75],"oropharyngeal":[76,248],"(pain":[78],"visual":[79],"analogue":[80],"scale":[81],"[VAS]":[82],">":[83,199],"=":[85,98,103,179,183,188],"4)":[86],"after":[87,232],"UPPP":[88,233],"were":[89,92,144,156],"recruited.":[90],"They":[91],"randomized":[93],"receive":[95],"TB":[96,192,225,244],"(n":[97,102],"7)":[99],"M&M":[101],"5).":[104],"Oropharyngeal":[105],"measured":[108],"by":[109,153,215],"VAS":[111,177],"Clinical":[114],"Global":[115],"Impression":[116],"Severity":[118],"(CGI-S)":[119],"Improvement":[121],"(CGI-I)":[122],"12th,":[125],"24th,":[126],"72th":[128],"hours":[129,148],"postoperatively.":[130,149],"Postoperative":[131],"related":[133],"morbidities":[134],"(PRMs)":[135],"quality":[137],"life":[139],"bodily":[141],"(QOL-BP)":[143],"also":[145,239],"evaluated":[146],"72":[147],"Adverse":[150],"events":[151],"incurred":[152],"treatment":[155],"carefully":[157],"monitored":[158],"during":[159],"patients'":[160],"hospitalizations.":[161],"RESULTS:":[162],"No":[163],"major":[164],"complication":[165],"occurred":[166],"throughout":[167],"study.":[169],"Analysis":[170],"clinical":[172],"measures":[173],"revealed":[174],"significantly":[175,227],"improved":[176],"(p":[178,182,187,198],"0.04),":[180],"CGI-S":[181],"0.03),":[184],"CGI-I":[186],"0.02)":[189],"group.":[193],"However,":[194],"no":[195],"significant":[196],"difference":[197],"0.05)":[200],"degree":[203],"found":[208],"between":[209],"two":[211],"groups,":[212],"as":[213],"denoted":[214],"aforementioned":[216],"three":[217],"variables,":[218],"PRMs,":[219],"QOL-BP.":[221],"CONCLUSIONS:":[222],"Administration":[223],"can":[226],"alleviate":[228],"wound":[230],"patients.":[236],"This":[237],"confirmed":[240],"safety":[242],"undergoing":[247],"surgery.":[249]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}