{"id":"https://openalex.org/W218944486","doi":null,"title":"Polymorphism of the C3 component of the complement system and its impact on serum lysozyme concentrations and complement activity.","display_name":"Polymorphism of the C3 component of the complement system and its impact on serum lysozyme concentrations and complement activity.","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W218944486","mag":"218944486"},"language":"en","primary_location":{"id":"pmh:oai:bpos.bg:22610","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/20.500.12641/22610","pdf_url":null,"source":{"id":"https://openalex.org/S7407055231","display_name":"Bulgarian Portal for Open Science","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/20.500.12641/22610","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004390792","display_name":"Tsvetoslav Koynarski","orcid":"https://orcid.org/0000-0003-1876-2372","observed_orcids":["https://orcid.org/0000-0003-1876-2372"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tsvetoslav Koynarski","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-1876-2372","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5040279670","display_name":"L. Sotirov","orcid":"https://orcid.org/0000-0002-5967-497X","observed_orcids":["https://orcid.org/0000-0002-5967-497X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L. Sotirov","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2882,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.52309246,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"4","issue":"2","first_page":"97","last_page":"101"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.7139000296592712,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.7139000296592712,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases","score":0.24150000512599945,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12322","display_name":"Animal health and immunology","score":0.03840000182390213,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/complement-c3","display_name":"complement C3","score":0.7749999761581421},{"id":"https://openalex.org/keywords/serum-lysozyme","display_name":"serum lysozyme","score":0.8339999914169312},{"id":"https://openalex.org/keywords/sheep-breeds","display_name":"sheep breeds","score":0.9539999961853027},{"id":"https://openalex.org/keywords/innate-immunity","display_name":"innate immunity","score":0.7070000171661377},{"id":"https://openalex.org/keywords/indirect-selection","display_name":"indirect selection","score":0.6669999957084656},{"id":"https://openalex.org/keywords/genetic-markers","display_name":"genetic markers","score":0.4259999990463257},{"id":"https://openalex.org/keywords/ile-de-france","display_name":"\u00cele-de-France","score":0.8889999985694885}],"concepts":[{"id":"https://openalex.org/C2776966407","wikidata":"https://www.wikidata.org/wiki/Q24779410","display_name":"Lysozyme","level":2,"score":0.7903298139572144},{"id":"https://openalex.org/C112313634","wikidata":"https://www.wikidata.org/wiki/Q7886648","display_name":"Complement (music)","level":5,"score":0.7411316633224487},{"id":"https://openalex.org/C168167062","wikidata":"https://www.wikidata.org/wiki/Q1117970","display_name":"Component (thermodynamics)","level":2,"score":0.6289795637130737},{"id":"https://openalex.org/C149737253","wikidata":"https://www.wikidata.org/wiki/Q3240252","display_name":"Polymorphism (computer science)","level":4,"score":0.48096075654029846},{"id":"https://openalex.org/C111684460","wikidata":"https://www.wikidata.org/wiki/Q334848","display_name":"Complement system","level":3,"score":0.48091599345207214},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4108029305934906},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3497433066368103},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3197634816169739},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2243654727935791},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.17218610644340515},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.15428265929222107},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07977128028869629},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.07727336883544922},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0},{"id":"https://openalex.org/C188082640","wikidata":"https://www.wikidata.org/wiki/Q1780899","display_name":"Complementation","level":4,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:bpos.bg:22610","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/20.500.12641/22610","pdf_url":null,"source":{"id":"https://openalex.org/S7407055231","display_name":"Bulgarian Portal for Open Science","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"},{"id":"mag:218944486","doi":null,"is_oa":false,"landing_page_url":"https://www.cabdirect.org/abstracts/20123237666.html","pdf_url":null,"source":{"id":"https://openalex.org/S2764393385","display_name":"Agricultural Science and Technology","issn_l":"1313-8820","issn":["1313-8820","1314-412X"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310314724","host_organization_name":"Trakia University. Faculty of Agriculture, Stara Zagora","host_organization_lineage":["https://openalex.org/P4310314724"],"host_organization_lineage_names":["Trakia University. Faculty of Agriculture, Stara Zagora"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Agricultural Science and Technology","raw_type":null}],"best_oa_location":{"id":"pmh:oai:bpos.bg:22610","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/20.500.12641/22610","pdf_url":null,"source":{"id":"https://openalex.org/S7407055231","display_name":"Bulgarian Portal for Open Science","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"},"sustainable_development_goals":[{"score":0.40450000762939453,"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2117583318","https://openalex.org/W2151018461","https://openalex.org/W7132530717","https://openalex.org/W7132522066","https://openalex.org/W344426804","https://openalex.org/W2135588702","https://openalex.org/W7132698571","https://openalex.org/W4283759205","https://openalex.org/W2415121826","https://openalex.org/W2099397137"],"abstract_inverted_index":{"The":[0,35,91],"aim":[1],"of":[2,10,14,21,29,78,87,131,149],"the":[3,8,11,15,19,26,84,115,122,129,147],"investigation":[4],"was":[5,37,89,118],"to":[6,45],"determine":[7],"influence":[9],"C3":[12,100,123],"component":[13],"complement":[16,30],"system":[17],"on":[18],"levels":[20,130,148],"blood":[22],"serum":[23,132],"lysozyme":[24,133],"and":[25,42,66,96,109,135],"alternative":[27],"pathway":[28],"activity":[31],"(APCA)":[32],"in":[33,153],"sheep.":[34,154],"experiment":[36],"carried":[38],"out":[39,120],"with":[40,111],"sheep":[41,47],"rams":[43],"belonging":[44],"nine":[46,99],"breeds":[48],"\u2013":[49],"Mouton":[50],"Charollais,":[51],"Ile":[52],"de":[53],"France,":[54],"Trakia":[55],"Merino,":[56],"Dairy":[57],"crosses,":[58],"White":[59],"Maritsa,":[60,62],"Patch-faced":[61],"Karnobat,":[63],"Pleven":[64],"Blackhead":[65],"Local":[67],"Stara":[68],"Zagora.":[69],"For":[70],"more":[71],"accurate":[72],"results":[73],"we":[74],"tested":[75],"equal":[76],"number":[77,86],"animals":[79],"from":[80],"each":[81],"breed":[82],"(48),":[83],"total":[85],"samples":[88],"432.":[90],"two":[92],"allelic":[93],"genes":[94],"(C3S":[95],"C3F)":[97],"formed":[98],"genotypes\u2013SS,":[101],"SS1,":[102],"FF,":[103],"FS,":[104],"FS5,":[105],"FS7,":[106],"FS10,":[107],"FF1,":[108],"F1F1":[110],"different":[112],"prevalence":[113],"between":[114],"breeds.":[116],"It":[117],"found":[119],"that":[121],"genotypes":[124],"do":[125],"not":[126,145],"impact":[127],"significantly":[128],"concentrations":[134],"APCA,":[136],"therefore":[137],"indirect":[138],"selection":[139],"after":[140],"this":[141],"gene":[142],"marker":[143],"will":[144],"improve":[146],"innate":[150],"immune":[151],"response":[152]},"counts_by_year":[{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2025-10-10T17:16:08.811792","created_date":"2016-06-24T00:00:00"}