{"id":"https://openalex.org/W2189290902","doi":null,"title":"An in vitro anticoagulant effect of Fenugreek (Trigonella foenum-graecum) in blood samples of normal Sudanese individuals.","display_name":"An in vitro anticoagulant effect of Fenugreek (Trigonella foenum-graecum) in blood samples of normal Sudanese individuals.","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2189290902","mag":"2189290902","pmid":"https://pubmed.ncbi.nlm.nih.gov/27493374","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4949941"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:3935081","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4949941","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4949941","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111836400","display_name":"Imad M. Taj Eldin","orcid":"https://orcid.org/0000-0002-4230-952X","observed_orcids":["https://orcid.org/0000-0002-4230-952X"]},"institutions":[{"id":"https://openalex.org/I78157869","display_name":"University of Gezira","ror":"https://ror.org/001mf9v16","country_code":"SD","type":"education","lineage":["https://openalex.org/I78157869"]}],"countries":["SD"],"is_corresponding":false,"raw_author_name":"Imadeldin M Taj Eldin","raw_affiliation_strings":["(1) Department of Pharmacology , Faculty of Pharmacy, University of Gezira , Sudan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"(1) Department of Pharmacology , Faculty of Pharmacy, University of Gezira , Sudan","institution_ids":["https://openalex.org/I78157869"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002544749","display_name":"Majed M Abdalmutalab","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Majed M Abdalmutalab","raw_affiliation_strings":["(2) Islamic Medical Association laboratory , Wad Medani , Sudan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"(2) Islamic Medical Association laboratory , Wad Medani , Sudan","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089937188","display_name":"Haydar E Bikir","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I78157869","display_name":"University of Gezira","ror":"https://ror.org/001mf9v16","country_code":"SD","type":"education","lineage":["https://openalex.org/I78157869"]}],"countries":["SD"],"is_corresponding":false,"raw_author_name":"Haydar E Bikir","raw_affiliation_strings":["(3) Postgraduate Medical studies , Faculty of Medicine, University of Gezira , Sudan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"(3) Postgraduate Medical studies , Faculty of Medicine, University of Gezira , Sudan","institution_ids":["https://openalex.org/I78157869"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":98},"biblio":{"volume":"13","issue":"2","first_page":"52","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.49880000948905945,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.49880000948905945,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.1527000069618225,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11721","display_name":"Blood properties and coagulation","score":0.15230000019073486,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fenugreek","display_name":"fenugreek","score":0.9990000128746033},{"id":"https://openalex.org/keywords/anticoagulant-activity","display_name":"anticoagulant activity","score":0.9399999976158142},{"id":"https://openalex.org/keywords/plant-aqueous-extracts","display_name":"aqueous plant extract","score":0.8889999985694885},{"id":"https://openalex.org/keywords/prothrombin-time","display_name":"prothrombin time","score":0.9919999837875366},{"id":"https://openalex.org/keywords/blood-coagulation","display_name":"coagulation","score":0.800000011920929},{"id":"https://openalex.org/keywords/hemostasis","display_name":"hemostasis","score":0.9710000157356262},{"id":"https://openalex.org/keywords/dose-dependent-effects","display_name":"dose-dependent effects","score":0.7400000095367432},{"id":"https://openalex.org/keywords/hypercoagulability","display_name":"hypercoagulability","score":0.8019999861717224},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.6620000004768372}],"concepts":[{"id":"https://openalex.org/C2778753648","wikidata":"https://www.wikidata.org/wiki/Q132655","display_name":"Trigonella","level":2,"score":0.9832321405410767},{"id":"https://openalex.org/C2778205648","wikidata":"https://www.wikidata.org/wiki/Q215118","display_name":"Anticoagulant","level":2,"score":0.7424575090408325},{"id":"https://openalex.org/C2780434524","wikidata":"https://www.wikidata.org/wiki/Q1144385","display_name":"Prothrombin time","level":2,"score":0.6733531951904297},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5777519941329956},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5561733841896057},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.5524131059646606},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5092214345932007},{"id":"https://openalex.org/C2778382381","wikidata":"https://www.wikidata.org/wiki/Q179217","display_name":"Coagulation","level":2,"score":0.4462246298789978},{"id":"https://openalex.org/C2993907526","wikidata":"https://www.wikidata.org/wiki/Q1259977","display_name":"Aqueous extract","level":2,"score":0.4196609854698181},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3894941806793213},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2505677342414856},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1766306459903717}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:europepmc.org:3935081","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4949941","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:27493374","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27493374","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sudanese journal of paediatrics","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4949941","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC4949941/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sudan J Paediatr","raw_type":"Text"},{"id":"mag:2189290902","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27493374","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:3935081","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4949941","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1794261056","https://openalex.org/W1858649922","https://openalex.org/W1985310665","https://openalex.org/W1995253545","https://openalex.org/W2002447805","https://openalex.org/W2009520402","https://openalex.org/W2020454028","https://openalex.org/W2046186673","https://openalex.org/W2119041802","https://openalex.org/W2144386438","https://openalex.org/W2149204290","https://openalex.org/W2170869207","https://openalex.org/W2171967315"],"related_works":["https://openalex.org/W2947563143","https://openalex.org/W3099279609","https://openalex.org/W7099742406","https://openalex.org/W3170312874","https://openalex.org/W7119500062","https://openalex.org/W4285592166","https://openalex.org/W2992920647","https://openalex.org/W2111334571","https://openalex.org/W2134350699","https://openalex.org/W3108731536"],"abstract_inverted_index":{"Haemostasis":[0],"is":[1,28],"the":[2,8,50,87,147],"process":[3,108],"of":[4,10,43,54,64,71,90,101],"forming":[5],"clots":[6],"in":[7,23,58,76,86,109,116,123,146,154],"walls":[9],"damaged":[11],"blood":[12,22,62,88],"vessels":[13],"to":[14,19,48,105,134,158],"prevent":[15,159],"abnormal":[16],"bleeding":[17],"and":[18,36,81,111,129,139,157],"maintain":[20],"intravascular":[21],"a":[24,117,150],"fluid":[25],"state.":[26],"Fenugreek":[27,55,72,102,120],"largely":[29],"universal":[30],"staple":[31],"herb,":[32],"popular":[33],"throughout":[34],"history":[35],"it":[37],"has":[38],"been":[39],"consumed":[40],"for":[41],"treatment":[42],"different":[44,77,124],"disorders.":[45],"We":[46],"aimed":[47],"study":[49],"possible":[51],"anticoagulant":[52,69,152],"effect":[53],"aqueous":[56,73,99,121],"extract":[57,74,100,122],"vitro":[59,68,110],"by":[60,93],"using":[61],"samples":[63,89],"normal":[65,91],"individuals.":[66],"In":[67],"effects":[70],"(5%)":[75],"volumes":[78],"(25,":[79],"50":[80],"75":[82],"\u03bcL)":[83],"were":[84],"examined":[85],"individuals":[92],"measuring":[94],"prothrombin":[95,114,131],"time":[96,115],"(PT).":[97],"The":[98],"was":[103],"found":[104],"inhibit":[106],"coagulation":[107],"significantly":[112],"prolonged":[113],"dose-dependent":[118],"manner.":[119],"concentrations":[125],"inhibits":[126],"clot":[127],"formation":[128],"increases":[130],"time.":[132],"Subject":[133],"further":[135],"studies":[136],"on":[137],"efficacy":[138],"safety,":[140],"It":[141],"can":[142],"well":[143],"be":[144],"used,":[145],"future,":[148],"as":[149],"supplementary":[151],"agent":[153],"cardiovascular":[155],"diseases":[156],"hypercoagulable":[160],"states.":[161]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}