{"id":"https://openalex.org/W2189175330","doi":null,"title":"Role of GGT in diagnosis of metabolic syndrome: a clinic-based cross-sectional survey.","display_name":"Role of GGT in diagnosis of metabolic syndrome: a clinic-based cross-sectional survey.","publication_year":2010,"publication_date":"2010-07-01","ids":{"openalex":"https://openalex.org/W2189175330","mag":"2189175330","pmid":"https://pubmed.ncbi.nlm.nih.gov/20693590"},"language":"en","primary_location":{"id":"pmid:20693590","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20693590","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Indian journal of medical research","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054466164","display_name":"Benan Kasapo\u011flu","orcid":"https://orcid.org/0000-0003-3858-0103","observed_orcids":["https://orcid.org/0000-0003-3858-0103"]},"institutions":[{"id":"https://openalex.org/I32462889","display_name":"Fatih University","ror":"https://ror.org/02wbrth70","country_code":"TR","type":"education","lineage":["https://openalex.org/I32462889","https://openalex.org/I67581229"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"B Kasapoglu","raw_affiliation_strings":["Fatih University Medical School, Department of Internal Medicine, Ankara, Turkey. benankasapoglu@hotmail.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fatih University Medical School, Department of Internal Medicine, Ankara, Turkey. benankasapoglu@hotmail.com","institution_ids":["https://openalex.org/I32462889"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080503559","display_name":"Cansel T\u00fcrkay","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C Turkay","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Y Bayram","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y Bayram","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5108481635","display_name":"Cemile Koca","orcid":"https://orcid.org/0000-0001-5175-4230","observed_orcids":["https://orcid.org/0000-0001-5175-4230"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C Koca","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.9407,"has_fulltext":false,"cited_by_count":40,"citation_normalized_percentile":{"value":0.8517645,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"132","issue":null,"first_page":"56","last_page":"61"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.5375999808311462,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.5375999808311462,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.45649999380111694,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12964","display_name":"Diet, Metabolism, and Disease","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gamma-glutamyl-transferase","display_name":"gamma-glutamyl transferase","score":0.9039999842643738},{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":0.9909999966621399},{"id":"https://openalex.org/keywords/liver-function-tests","display_name":"liver function tests","score":0.9160000085830688},{"id":"https://openalex.org/keywords/alanine-aminotransferase","display_name":"alanine aminotransferase","score":0.871999979019165},{"id":"https://openalex.org/keywords/aspartate-aminotransferase","display_name":"aspartate aminotransferase","score":1.0},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.7590000033378601},{"id":"https://openalex.org/keywords/hepatic-steatosis","display_name":"hepatic steatosis","score":0.5270000100135803},{"id":"https://openalex.org/keywords/diagnostic-biomarkers","display_name":"diagnostic biomarkers","score":0.5979999899864197},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.3490000069141388}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7494425177574158},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7006340026855469},{"id":"https://openalex.org/C2781278919","wikidata":"https://www.wikidata.org/wiki/Q285870","display_name":"Gamma-glutamyltransferase","level":3,"score":0.675284206867218},{"id":"https://openalex.org/C68443243","wikidata":"https://www.wikidata.org/wiki/Q2786686","display_name":"Quartile","level":3,"score":0.6495805978775024},{"id":"https://openalex.org/C142052008","wikidata":"https://www.wikidata.org/wiki/Q954027","display_name":"Cross-sectional study","level":2,"score":0.6411588788032532},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.6143657565116882},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.5497546195983887},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.5288844108581543},{"id":"https://openalex.org/C2992872382","wikidata":"https://www.wikidata.org/wiki/Q305481","display_name":"Alanine aminotransferase","level":2,"score":0.5061673521995544},{"id":"https://openalex.org/C2780578515","wikidata":"https://www.wikidata.org/wiki/Q657193","display_name":"Metabolic syndrome","level":3,"score":0.4886322617530823},{"id":"https://openalex.org/C2992208098","wikidata":"https://www.wikidata.org/wiki/Q1359801","display_name":"Liver function","level":2,"score":0.48445725440979004},{"id":"https://openalex.org/C512861765","wikidata":"https://www.wikidata.org/wiki/Q1359801","display_name":"Liver function tests","level":2,"score":0.477762371301651},{"id":"https://openalex.org/C2778606649","wikidata":"https://www.wikidata.org/wiki/Q305481","display_name":"Alanine transaminase","level":2,"score":0.4715682864189148},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.32518270611763},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.24554091691970825},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.20592114329338074},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.19059306383132935},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1896819770336151},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.09567943215370178},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0858975350856781}],"mesh":[{"descriptor_ui":"D000410","descriptor_name":"Alanine Transaminase","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001219","descriptor_name":"Aspartate Aminotransferases","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005723","descriptor_name":"gamma-Glutamyltransferase","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008111","descriptor_name":"Liver Function Tests","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008111","descriptor_name":"Liver Function Tests","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016017","descriptor_name":"Odds Ratio","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D024821","descriptor_name":"Metabolic Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D024821","descriptor_name":"Metabolic Syndrome","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D024821","descriptor_name":"Metabolic Syndrome","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true}],"locations_count":3,"locations":[{"id":"pmid:20693590","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20693590","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Indian journal of medical research","raw_type":"Journal Article"},{"id":"pmh:942a5cda-54a4-420e-959c-820025982cb7","doi":null,"is_oa":false,"landing_page_url":"https://avesis.aybu.edu.tr/publication/details/942a5cda-54a4-420e-959c-820025982cb7/oai","pdf_url":null,"source":{"id":"https://openalex.org/S7407055213","display_name":"AYBU AVESIS","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"mag:2189175330","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20693590","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W164653050","https://openalex.org/W1946263363","https://openalex.org/W1963739832","https://openalex.org/W1969564411","https://openalex.org/W1977338615","https://openalex.org/W1982191867","https://openalex.org/W2002557725","https://openalex.org/W2011556186","https://openalex.org/W2011801069","https://openalex.org/W2021304489","https://openalex.org/W2032549598","https://openalex.org/W2040538211","https://openalex.org/W2067866675","https://openalex.org/W2072390396","https://openalex.org/W2107732097","https://openalex.org/W2108916652","https://openalex.org/W2111408436","https://openalex.org/W2123289485","https://openalex.org/W2126732462","https://openalex.org/W2127510700","https://openalex.org/W2154774609","https://openalex.org/W2181441354","https://openalex.org/W2415296771","https://openalex.org/W2418699414","https://openalex.org/W2477872031","https://openalex.org/W4249825849"],"related_works":["https://openalex.org/W4249376463","https://openalex.org/W2128830987","https://openalex.org/W3011033077","https://openalex.org/W2740392634","https://openalex.org/W4390355637","https://openalex.org/W2390956791","https://openalex.org/W2246977394","https://openalex.org/W7100329278","https://openalex.org/W4415312490","https://openalex.org/W6949338225"],"abstract_inverted_index":{"BACKGROUND":[0],"&":[1,241],"OBJECTIVES:":[2],"The":[3,87,108],"aim":[4],"of":[5,28,48,81,90,111,140,234,261,272],"this":[6],"study":[7,36],"is":[8,136,147,158,168],"to":[9,229,264,284],"know":[10],"if":[11],"the":[12,82,134,141,163,265,268],"liver":[13,71,112,244],"function":[14,72],"tests":[15,274],"(LFT),":[16],"especially":[17,250,280],"gamma":[18],"glutamyl":[19],"transferase":[20,93],"(GGT),":[21],"have":[22,282],"a":[23,213,255],"predictive":[24],"value":[25],"in":[26,105,118,145,210,247,258,275,287],"diagnosis":[27,260],"metabolic":[29,290],"syndrome":[30],"(MS).":[31],"METHODS:":[32],"A":[33],"cross-sectional,":[34],"single-center":[35],"was":[37,182,216],"carried":[38],"out":[39],"with":[40,53,55,150,162,219],"908":[41],"subjects.":[42,68],"Four":[43],"hundred":[44],"and":[45,63,78,98,123,189,197,204,237,270],"forty":[46],"two":[47],"these":[49,273],"subjects":[50,83,117],"were":[51,61,84,101],"diagnosed":[52],"MS":[54,106,119,152,190,198,211],"IDF":[56,164,171],"criteria;":[57,200],"while":[58],"other":[59],"466":[60],"sex":[62,196,236],"age":[64],"matched":[65],"healthy":[66],"control":[67],"Blood":[69],"pressure,":[70],"tests,":[73],"fasting":[74],"blood":[75,176],"glucose":[76],"levels":[77,100,188],"lipid":[79],"profile":[80],"recorded.":[85],"RESULTS:":[86],"mean":[88,109],"values":[89,110],"alanine":[91],"amino":[92],"(ALT),":[94],"aspartate":[95],"aminotransferase":[96],"(AST)":[97],"GGT":[99,124,142,146,157,187,215,231],"statistically":[102],"significantly":[103],"higher":[104],"group.":[107],"enzymes,":[113,245],"for":[114,194,289],"female/":[115],"male":[116],"group,":[120,212],"AST;":[121],"ALT":[122,205],"respectively,":[125],"were;":[126],"20.5/19.7":[127],"U/l;":[128,130],"25.9/28.5":[129],"35.9/42.1":[131],"U/l.":[132],"When":[133],"sample":[135],"divided":[137],"into":[138],"quartiles":[139],"levels,":[143],"increase":[144],"positively":[148,217],"correlated":[149],"increased":[151],"prevalence.":[153],"In":[154,178,207],"ROC":[155],"analysis":[156],"as":[159,167],"strongly":[160],"associated":[161,218],"diagnostic":[165,199],"components":[166],"each":[169],"individual":[170],"component,":[172],"except":[173],"elevated":[174,186],"systolic":[175],"pressure.":[177],"covariance":[179],"analysis,":[180,209],"there":[181],"significant":[183],"relationship":[184],"between":[185],"presence":[191],"after":[192],"adjustment":[193],"age,":[195,235],"but":[201],"not":[202],"AST":[203],"levels.":[206],"multivariance":[208],"high":[214],"CVD":[220],"prevalance":[221],"(odds":[222],"ratio:":[223],"2.011,":[224],"95%":[225],"CI":[226],"1.10-4.57)":[227],"compared":[228],"low":[230],"group":[232],"independent":[233],"smoking":[238],"habits.":[239],"INTERPRETATION":[240],"CONCLUSIONS:":[242],"Elevated":[243],"although":[246],"normal":[248],"ranges,":[249],"at":[251],"upper":[252],"quartiles,":[253],"play":[254],"central":[256],"role":[257],"early":[259],"fat":[262],"overflow":[263],"liver.":[266],"Regarding":[267],"availability":[269],"simplicity":[271],"routine":[276],"clinical":[277],"practice,":[278],"they,":[279],"GGT,":[281],"potential":[283],"be":[285],"considered":[286],"algorithms":[288],"syndrome.":[291]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}