{"id":"https://openalex.org/W2189154756","doi":null,"title":"Review Article Positron emission tomography (PET) imaging with","display_name":"Review Article Positron emission tomography (PET) imaging with","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W2189154756","mag":"2189154756"},"language":"en","primary_location":{"id":"mag:2189154756","doi":null,"is_oa":false,"landing_page_url":"http://ajnmmi.us/files/ajnmmi1109002.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064151398","display_name":"Mian M. Alauddin","orcid":"https://orcid.org/0000-0002-0954-3605","observed_orcids":["https://orcid.org/0000-0002-0954-3605"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Mian M. Alauddin","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-0954-3605","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5064151398"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.19509708,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11395","display_name":"Radiopharmaceutical Chemistry and Applications","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.004999999888241291,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13561","display_name":"Chemical Reactions and Isotopes","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/positron-emission-tomography","display_name":"positron emission tomography","score":0.9990000128746033},{"id":"https://openalex.org/keywords/fluorine-18","display_name":"fluorine-18","score":0.9620000123977661},{"id":"https://openalex.org/keywords/radiofluorination","display_name":"radiofluorination","score":0.8389999866485596},{"id":"https://openalex.org/keywords/fluorination","display_name":"fluorination","score":0.7850000262260437},{"id":"https://openalex.org/keywords/18f-fdg","display_name":"18F-FDG","score":0.9290000200271606},{"id":"https://openalex.org/keywords/glucose-metabolism-imaging","display_name":"glucose metabolism imaging","score":0.6809999942779541},{"id":"https://openalex.org/keywords/tumor-detection","display_name":"tumor detection","score":0.8429999947547913},{"id":"https://openalex.org/keywords/radioactive-tracers","display_name":"radioactive tracers","score":0.6650000214576721},{"id":"https://openalex.org/keywords/tumor-imaging","display_name":"tumor imaging","score":0.44200000166893005}],"concepts":[{"id":"https://openalex.org/C2775842073","wikidata":"https://www.wikidata.org/wiki/Q208376","display_name":"Positron emission tomography","level":2,"score":0.9119309186935425},{"id":"https://openalex.org/C3017724952","wikidata":"https://www.wikidata.org/wiki/Q208376","display_name":"Pet imaging","level":3,"score":0.695754885673523},{"id":"https://openalex.org/C49853544","wikidata":"https://www.wikidata.org/wiki/Q206229","display_name":"Biomolecule","level":2,"score":0.6425224542617798},{"id":"https://openalex.org/C202100949","wikidata":"https://www.wikidata.org/wiki/Q3229","display_name":"Positron","level":3,"score":0.6155025362968445},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.587864100933075},{"id":"https://openalex.org/C136339569","wikidata":"https://www.wikidata.org/wiki/Q1142297","display_name":"Molecular imaging","level":3,"score":0.5411436557769775},{"id":"https://openalex.org/C177322064","wikidata":"https://www.wikidata.org/wiki/Q750955","display_name":"Radiochemistry","level":1,"score":0.5258967280387878},{"id":"https://openalex.org/C127077266","wikidata":"https://www.wikidata.org/wiki/Q3488638","display_name":"PET-CT","level":3,"score":0.4720381498336792},{"id":"https://openalex.org/C112390072","wikidata":"https://www.wikidata.org/wiki/Q4955834","display_name":"Brain positron emission tomography","level":4,"score":0.4659356474876404},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.457226425409317},{"id":"https://openalex.org/C182752723","wikidata":"https://www.wikidata.org/wiki/Q1474590","display_name":"Functional imaging","level":2,"score":0.44222551584243774},{"id":"https://openalex.org/C29331040","wikidata":"https://www.wikidata.org/wiki/Q7239554","display_name":"Preclinical imaging","level":3,"score":0.3565980792045593},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.350229948759079},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28627678751945496},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.20549806952476501},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.17852795124053955},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.1358109712600708},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.13335633277893066},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0932040810585022},{"id":"https://openalex.org/C185544564","wikidata":"https://www.wikidata.org/wiki/Q81197","display_name":"Nuclear physics","level":1,"score":0.07663652300834656},{"id":"https://openalex.org/C147120987","wikidata":"https://www.wikidata.org/wiki/Q2225","display_name":"Electron","level":2,"score":0.0},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2189154756","doi":null,"is_oa":false,"landing_page_url":"http://ajnmmi.us/files/ajnmmi1109002.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":116,"referenced_works":["https://openalex.org/W12167749","https://openalex.org/W66097355","https://openalex.org/W1516926652","https://openalex.org/W1576591897","https://openalex.org/W1924219923","https://openalex.org/W1930781902","https://openalex.org/W1935191222","https://openalex.org/W1969489549","https://openalex.org/W1970648991","https://openalex.org/W1971288173","https://openalex.org/W1973705376","https://openalex.org/W1975617027","https://openalex.org/W1976424313","https://openalex.org/W1977854718","https://openalex.org/W1979398201","https://openalex.org/W1979743501","https://openalex.org/W1979876729","https://openalex.org/W1980210856","https://openalex.org/W1980260496","https://openalex.org/W1980718355","https://openalex.org/W1982461399","https://openalex.org/W1983786329","https://openalex.org/W1983793094","https://openalex.org/W1987934775","https://openalex.org/W1988177860","https://openalex.org/W1988840268","https://openalex.org/W1989170359","https://openalex.org/W1992795850","https://openalex.org/W1995531141","https://openalex.org/W1995689598","https://openalex.org/W1997840637","https://openalex.org/W1999081489","https://openalex.org/W1999625705","https://openalex.org/W1999656185","https://openalex.org/W2001468757","https://openalex.org/W2002042920","https://openalex.org/W2005109049","https://openalex.org/W2017564917","https://openalex.org/W2017712098","https://openalex.org/W2018239968","https://openalex.org/W2023438612","https://openalex.org/W2023843590","https://openalex.org/W2024928163","https://openalex.org/W2025058554","https://openalex.org/W2025130298","https://openalex.org/W2030587115","https://openalex.org/W2030624477","https://openalex.org/W2032158647","https://openalex.org/W2032643964","https://openalex.org/W2034135634","https://openalex.org/W2038057738","https://openalex.org/W2039559374","https://openalex.org/W2044076900","https://openalex.org/W2045102424","https://openalex.org/W2057843201","https://openalex.org/W2061669618","https://openalex.org/W2065912583","https://openalex.org/W2071076853","https://openalex.org/W2076052242","https://openalex.org/W2076382064","https://openalex.org/W2080431464","https://openalex.org/W2082320594","https://openalex.org/W2084518024","https://openalex.org/W2084664715","https://openalex.org/W2085533853","https://openalex.org/W2086184737","https://openalex.org/W2086749473","https://openalex.org/W2088788493","https://openalex.org/W2092940972","https://openalex.org/W2097593804","https://openalex.org/W2099569385","https://openalex.org/W2104375206","https://openalex.org/W2106194191","https://openalex.org/W2110511446","https://openalex.org/W2110997670","https://openalex.org/W2112039607","https://openalex.org/W2115229958","https://openalex.org/W2115367933","https://openalex.org/W2117665515","https://openalex.org/W2120555115","https://openalex.org/W2123246617","https://openalex.org/W2133525371","https://openalex.org/W2134725504","https://openalex.org/W2134909191","https://openalex.org/W2140026659","https://openalex.org/W2141070882","https://openalex.org/W2142591952","https://openalex.org/W2144163438","https://openalex.org/W2144869962","https://openalex.org/W2146702849","https://openalex.org/W2147960486","https://openalex.org/W2149327053","https://openalex.org/W2149644390","https://openalex.org/W2151774893","https://openalex.org/W2151879275","https://openalex.org/W2155957746","https://openalex.org/W2163660556","https://openalex.org/W2164230553","https://openalex.org/W2164813102","https://openalex.org/W2172299296","https://openalex.org/W2180991434","https://openalex.org/W2182762443","https://openalex.org/W2183324061","https://openalex.org/W2184889437","https://openalex.org/W2188024599","https://openalex.org/W2232925116","https://openalex.org/W2260527364","https://openalex.org/W2264395641","https://openalex.org/W2271853326","https://openalex.org/W2273539664","https://openalex.org/W2319347090","https://openalex.org/W2328838310","https://openalex.org/W2411790861","https://openalex.org/W2567675072","https://openalex.org/W2595191862","https://openalex.org/W2879316556"],"related_works":["https://openalex.org/W2314687714","https://openalex.org/W2021958510","https://openalex.org/W4237545182","https://openalex.org/W2478375802","https://openalex.org/W2502267555","https://openalex.org/W2509378822","https://openalex.org/W2316439331","https://openalex.org/W2990559803","https://openalex.org/W4294233232","https://openalex.org/W2084693381"],"abstract_inverted_index":{"Positron":[0],"Emission":[1],"Tomography":[2],"(PET)":[3],"is":[4,11,43,52,82,150],"a":[5],"nuclear":[6],"medicine":[7],"imaging":[8,40,149],"technique":[9],"that":[10,51],"widely":[12],"used":[13,54,79,120],"in":[14,55,108,121,147],"early":[15,91],"detection":[16,92],"and":[17,67,114,134,139,144],"treatment":[18],"follow":[19],"up":[20],"of":[21,45,49,57,62,70,88,93,97,106,110,141],"many":[22],"diseases,":[23],"including":[24],"cancer.":[25],"This":[26],"modality":[27],"requires":[28],"positron-emitting":[29],"iso-":[30],"tope":[31],"labeled":[32],"biomolecules,":[33],"which":[34],"are":[35,118],"synthesized":[36],"prior":[37],"to":[38,123],"perform":[39],"studies.":[41],"Fluorine-18":[42],"one":[44],"the":[46,103,125],"several":[47],"isotopes":[48],"fluorine":[50],"routinely":[53],"radiolabeling":[56,140],"biomolecules":[58],"for":[59,80,90],"PET;":[60],"because":[61],"its":[63],"positron":[64],"emitting":[65],"property":[66],"favorable":[68],"half-life":[69],"109.8":[71],"min.":[72],"The":[73,95],"biologically":[74],"active":[75],"molecule":[76],"most":[77],"commonly":[78],"PET":[81,122,148],"2-deoxy":[83],"-2-18F-fluoro-\u03b2-D-glucose":[84],"(18F-FDG),":[85],"an":[86],"analogue":[87],"glucose,":[89],"tumors.":[94],"concentrations":[96],"tracer":[98],"accumulation":[99],"(PET":[100],"image)":[101],"demonstrate":[102],"metabolic":[104],"activity":[105],"tissues":[107],"terms":[109],"regional":[111],"glucose":[112],"metabolism":[113],"accumulation.":[115],"Other":[116],"tracers":[117],"also":[119],"image":[124],"tissue":[126],"concentration.":[127],"In":[128],"this":[129],"review,":[130],"information":[131],"on":[132],"fluorination":[133],"radiofluorination":[135],"reactions,":[136],"radiofluorinating":[137],"agents,":[138],"various":[142],"compounds":[143],"their":[145],"application":[146],"presented.":[151]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}