{"id":"https://openalex.org/W2189063958","doi":null,"title":"A Study on the Effectiveness of Acarbose in combination with other Hypoglycemic Agents in Reducing Blood Glucose Values in Type 2 Diabetes","display_name":"A Study on the Effectiveness of Acarbose in combination with other Hypoglycemic Agents in Reducing Blood Glucose Values in Type 2 Diabetes","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W2189063958","mag":"2189063958"},"language":"en","primary_location":{"id":"mag:2189063958","doi":null,"is_oa":false,"landing_page_url":"http://ijapbc.com/files/17-1436.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068525541","display_name":"Sheena Marin Thomas","orcid":"https://orcid.org/0000-0003-1635-2716","observed_orcids":["https://orcid.org/0000-0003-1635-2716"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sheena Marin Thomas","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5061092228","display_name":"Bincy Varghese","orcid":"https://orcid.org/0000-0002-4610-3246","observed_orcids":["https://orcid.org/0000-0002-4610-3246"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bincy Varghese","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-4610-3246","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acarbose","display_name":"acarbose","score":0.996999979019165},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9660000205039978},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.8399999737739563},{"id":"https://openalex.org/keywords/oral-antidiabetic-drugs","display_name":"oral antidiabetic drugs","score":0.9929999709129333},{"id":"https://openalex.org/keywords/postprandial-blood-glucose","display_name":"postprandial blood glucose","score":0.9449999928474426},{"id":"https://openalex.org/keywords/hba1c","display_name":"HbA1c","score":0.9169999957084656},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.8740000128746033},{"id":"https://openalex.org/keywords/glycemic-control","display_name":"glycemic control","score":0.7260000109672546},{"id":"https://openalex.org/keywords/drug-efficacy-and-safety","display_name":"drug safety and efficacy","score":0.7770000100135803}],"concepts":[{"id":"https://openalex.org/C2776617576","wikidata":"https://www.wikidata.org/wiki/Q338005","display_name":"Acarbose","level":3,"score":0.9853096008300781},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8578345775604248},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5947344899177551},{"id":"https://openalex.org/C2778917026","wikidata":"https://www.wikidata.org/wiki/Q43041","display_name":"Hemoglobin","level":2,"score":0.5805745124816895},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.5383670330047607},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.5234096646308899},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5070545673370361},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.47578752040863037},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.43487656116485596},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3005611002445221},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2189063958","doi":null,"is_oa":false,"landing_page_url":"http://ijapbc.com/files/17-1436.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1976369579","https://openalex.org/W2017777092","https://openalex.org/W2041883344","https://openalex.org/W2048433033","https://openalex.org/W2087536878","https://openalex.org/W2120471801","https://openalex.org/W2165099877","https://openalex.org/W2168707041","https://openalex.org/W2484312744"],"related_works":["https://openalex.org/W3029976898","https://openalex.org/W2254507804","https://openalex.org/W2379501405","https://openalex.org/W2923322584","https://openalex.org/W2015950058","https://openalex.org/W2083333813","https://openalex.org/W2017777092","https://openalex.org/W2359096866","https://openalex.org/W2388105763","https://openalex.org/W2375970232"],"abstract_inverted_index":{"Objective":[0],"-":[1],"To":[2],"obtain":[3],"data":[4],"on":[5,44,95,194],"efficacy":[6],"and":[7,47,73,106,109,120,138,154,181,191,203,214,223,230],"safety":[8],"of":[9,26,35,61,146,179,212],"Acarbose":[10,45,66,147,165,184,226],"combination":[11],"therapy":[12,46,227],"during":[13],"daily":[14,234],"life":[15,235],"treatment.":[16],"Methods-":[17],"It\u2019s":[18],"a":[19,24,30,59],"prospective":[20],"study":[21,132],"done":[22],"for":[23,71,81],"period":[25,60],"7":[27],"months":[28,63],"in":[29,51,64,74,85,89,113,124,160,164,183,219,233,236],"south":[31],"Indian":[32],"hospital.":[33],"Out":[34],"74":[36],"Type":[37],"II":[38,240],"diabetic":[39],"patients":[40,42,49,69,79,101,221,237],"40":[41],"were":[43,50,92,102,127,136,141,149,197],"34":[48],"another":[52],"group":[53,67,77,126,166,185],"taking":[54],"oral":[55,173],"hypoglycemics":[56,174],"alone.":[57,175],"After":[58],"three":[62],"the":[65,75,100,110,131],"35":[68],"came":[70,80],"review":[72],"other":[76],"26":[78],"review.":[82],"The":[83,143,157,176,209],"reduction":[84,112,159],"blood":[86,116,161],"glucose":[87,117,162],"profile":[88],"both":[90],"groups":[91],"done.":[93],"Based":[94,193],"body":[96],"mass":[97],"index":[98],"(BMI)":[99],"classified":[103,198],"as":[104,199,206],"obese":[105,108,202,220],"non":[107,207],"significant":[111,218],"post":[114],"prandial":[115],"level":[118],"(PPBS)":[119],"glycosylated":[121],"hemoglobin":[122],"(HbA1C)":[123],"each":[125],"determined.":[128],"Results-":[129],"Among":[130],"population":[133],"42":[134],"(56.7%)":[135],"male":[137],"59":[139],"(43.2%)":[140],"female.":[142],"different":[144],"doses":[145],"prescribed":[148],"25mg":[150],"(48.64%),":[151],"50mg":[152],"(37.83%)":[153],"100mg":[155],"(13.51%).":[156],"percentage":[158],"values":[163],"was":[167,186,216,228],"found":[168,187],"to":[169,188],"be":[170,189],"higher":[171],"than":[172],"p":[177,210],"value":[178,211],"PPBS":[180,213],"HbA1C":[182,215],"(p=0.002)":[190],"(p=0.043).":[192],"BMI":[195],"they":[196],"27":[200],"(77.14)":[201],"8":[204],"(22.8)":[205],"obese.":[208],"highly":[217],"(p=0.0006)":[222],"(p<0.0001).":[224],"Conclusion-":[225],"efficacious":[229],"well":[231],"tolerated":[232],"with":[238],"type":[239],"diabetes":[241],"mellitus.":[242]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2016-06-24T00:00:00"}