{"id":"https://openalex.org/W2188977977","doi":null,"title":"Prostaglandins, Leukotrienes and Essential Fatty Acids","display_name":"Prostaglandins, Leukotrienes and Essential Fatty Acids","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W2188977977","mag":"2188977977"},"language":"en","primary_location":{"id":"mag:2188977977","doi":null,"is_oa":false,"landing_page_url":"http://info.babymilkaction.org/files/Brenna%202008%20ISSFAL%20statement%20ALA%20supplementaiton%20and%20conversion%20to%20LC%20PUFAS%20in%20humans.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056488821","display_name":"Gunveen Kaur","orcid":"https://orcid.org/0000-0002-6250-0495","observed_orcids":["https://orcid.org/0000-0002-6250-0495"]},"institutions":[{"id":"https://openalex.org/I149704539","display_name":"Deakin University","ror":"https://ror.org/02czsnj07","country_code":"AU","type":"education","lineage":["https://openalex.org/I149704539"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Gunveen Kaur","raw_affiliation_strings":["Deakin University"],"raw_orcid":"https://orcid.org/0000-0002-6250-0495","affiliations":[{"raw_affiliation_string":"Deakin University","institution_ids":["https://openalex.org/I149704539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018868735","display_name":"Andrew James Sinclair","orcid":"https://orcid.org/0000-0002-9515-9721","observed_orcids":["https://orcid.org/0000-0002-9515-9721"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrew J. Sinclair","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-9515-9721","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024814922","display_name":"David Cameron\u2010Smith","orcid":"https://orcid.org/0000-0002-0144-5816","observed_orcids":["https://orcid.org/0000-0002-0144-5816"]},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Cameron\u2010Smith","raw_affiliation_strings":["Columbia University"],"raw_orcid":"https://orcid.org/0000-0002-0144-5816","affiliations":[{"raw_affiliation_string":"Columbia University","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Daniel P. Barr","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I39387349","display_name":"University of Chieti-Pescara","ror":"https://ror.org/00qjgza05","country_code":"IT","type":"education","lineage":["https://openalex.org/I39387349"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Daniel P. Barr","raw_affiliation_strings":["University of Chieti-Pescara"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Chieti-Pescara","institution_ids":["https://openalex.org/I39387349"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028300485","display_name":"Juan Carlos Molero","orcid":"https://orcid.org/0000-0002-2728-7019","observed_orcids":["https://orcid.org/0000-0002-2728-7019"]},"institutions":[{"id":"https://openalex.org/I34352273","display_name":"Maastricht University","ror":"https://ror.org/02jz4aj89","country_code":"NL","type":"education","lineage":["https://openalex.org/I34352273"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Juan Carlos Molero-Navajas","raw_affiliation_strings":["Maastricht University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Maastricht University","institution_ids":["https://openalex.org/I34352273"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053163967","display_name":"Nicky Konstantopoulos","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nicky Konstantopoulos","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":8.1454,"has_fulltext":false,"cited_by_count":321,"citation_normalized_percentile":{"value":0.97758591,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10450","display_name":"Aquaculture Nutrition and Growth","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/docosapentaenoic-acid","display_name":"docosapentaenoic acid","score":0.9990000128746033},{"id":"https://openalex.org/keywords/eicosapentaenoic-acid","display_name":"eicosapentaenoic acid","score":0.949999988079071},{"id":"https://openalex.org/keywords/docosahexaenoic-acid","display_name":"docosahexaenoic acid","score":1.0},{"id":"https://openalex.org/keywords/omega-3-fatty-acids","display_name":"omega-3 fatty acids","score":0.8840000033378601},{"id":"https://openalex.org/keywords/srebp-1c","display_name":"SREBP-1c","score":0.9049999713897705},{"id":"https://openalex.org/keywords/hepatic-lipogenesis","display_name":"hepatic lipogenesis","score":0.7129999995231628},{"id":"https://openalex.org/keywords/fatty-acid-synthesis","display_name":"fatty acid synthesis","score":0.7590000033378601},{"id":"https://openalex.org/keywords/hmg-coa-reductase","display_name":"HMG-CoA reductase","score":0.9549999833106995},{"id":"https://openalex.org/keywords/acetyl-coa-carboxylase","display_name":"acetyl-CoA carboxylase","score":0.9120000004768372},{"id":"https://openalex.org/keywords/fatty-acid-synthase","display_name":"fatty acid synthase","score":0.9990000128746033},{"id":"https://openalex.org/keywords/lipogenic-gene-expression","display_name":"lipogenic gene expression","score":0.6600000262260437},{"id":"https://openalex.org/keywords/phospholipid-fatty-acid-composition","display_name":"phospholipid fatty acid composition","score":0.8410000205039978},{"id":"https://openalex.org/keywords/rat-hepatocytes","display_name":"rat hepatocytes","score":0.41999998688697815}],"concepts":[{"id":"https://openalex.org/C2781349093","wikidata":"https://www.wikidata.org/wiki/Q17177300","display_name":"Docosapentaenoic acid","level":5,"score":0.8248050212860107},{"id":"https://openalex.org/C48289651","wikidata":"https://www.wikidata.org/wiki/Q106916817","display_name":"Fatty acid synthase","level":3,"score":0.7793385982513428},{"id":"https://openalex.org/C2777171753","wikidata":"https://www.wikidata.org/wiki/Q423345","display_name":"Docosahexaenoic acid","level":4,"score":0.7118191719055176},{"id":"https://openalex.org/C2776091944","wikidata":"https://www.wikidata.org/wiki/Q409990","display_name":"Eicosapentaenoic acid","level":4,"score":0.6132254600524902},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5616191625595093},{"id":"https://openalex.org/C85051948","wikidata":"https://www.wikidata.org/wiki/Q416064","display_name":"Sterol regulatory element-binding protein","level":4,"score":0.5447183847427368},{"id":"https://openalex.org/C2779123261","wikidata":"https://www.wikidata.org/wiki/Q407635","display_name":"Coenzyme A","level":4,"score":0.5377135276794434},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.5347838401794434},{"id":"https://openalex.org/C19038510","wikidata":"https://www.wikidata.org/wiki/Q2005087","display_name":"Polyunsaturated fatty acid","level":3,"score":0.4663516581058502},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4549831748008728},{"id":"https://openalex.org/C2776941171","wikidata":"https://www.wikidata.org/wiki/Q900209","display_name":"Fatty acid synthesis","level":3,"score":0.43361395597457886},{"id":"https://openalex.org/C2779828298","wikidata":"https://www.wikidata.org/wiki/Q4035577","display_name":"CD36","level":3,"score":0.4296319782733917},{"id":"https://openalex.org/C2781403372","wikidata":"https://www.wikidata.org/wiki/Q207688","display_name":"Oleic acid","level":2,"score":0.42605969309806824},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3916813135147095},{"id":"https://openalex.org/C134651460","wikidata":"https://www.wikidata.org/wiki/Q3100717","display_name":"Reductase","level":3,"score":0.3650169372558594},{"id":"https://openalex.org/C2778718757","wikidata":"https://www.wikidata.org/wiki/Q143623","display_name":"Sterol","level":3,"score":0.30579349398612976},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.2756073772907257},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.22226890921592712},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08322614431381226}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2188977977","doi":null,"is_oa":false,"landing_page_url":"http://info.babymilkaction.org/files/Brenna%202008%20ISSFAL%20statement%20ALA%20supplementaiton%20and%20conversion%20to%20LC%20PUFAS%20in%20humans.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8560000061988831,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":519,"referenced_works":["https://openalex.org/W1153830","https://openalex.org/W26296931","https://openalex.org/W59509408","https://openalex.org/W68250443","https://openalex.org/W81324557","https://openalex.org/W82460519","https://openalex.org/W94256558","https://openalex.org/W146546530","https://openalex.org/W153902777","https://openalex.org/W181063792","https://openalex.org/W193604910","https://openalex.org/W272111838","https://openalex.org/W328561729","https://openalex.org/W777578576","https://openalex.org/W976844117","https://openalex.org/W1239246082","https://openalex.org/W1480078612","https://openalex.org/W1487144814","https://openalex.org/W1488817590","https://openalex.org/W1490261790","https://openalex.org/W1490452970","https://openalex.org/W1491700890","https://openalex.org/W1497630404","https://openalex.org/W1513732013","https://openalex.org/W1517011095","https://openalex.org/W1522335173","https://openalex.org/W1532082124","https://openalex.org/W1550747483","https://openalex.org/W1550917147","https://openalex.org/W1553790148","https://openalex.org/W1555174877","https://openalex.org/W1561059299","https://openalex.org/W1566489422","https://openalex.org/W1569736468","https://openalex.org/W1578779604","https://openalex.org/W1589823408","https://openalex.org/W1597746336","https://openalex.org/W1629308315","https://openalex.org/W1629878108","https://openalex.org/W1644344232","https://openalex.org/W1674585484","https://openalex.org/W1775749144","https://openalex.org/W1781305560","https://openalex.org/W1857358306","https://openalex.org/W1876053957","https://openalex.org/W1884359734","https://openalex.org/W1893083459","https://openalex.org/W1896271480","https://openalex.org/W1897536934","https://openalex.org/W1900762885","https://openalex.org/W1902942903","https://openalex.org/W1903183160","https://openalex.org/W1905475768","https://openalex.org/W1906834912","https://openalex.org/W1907710778","https://openalex.org/W1910238291","https://openalex.org/W1911154327","https://openalex.org/W1911310383","https://openalex.org/W1921371649","https://openalex.org/W1925942814","https://openalex.org/W1926170255","https://openalex.org/W1929906524","https://openalex.org/W1932182428","https://openalex.org/W1938646558","https://openalex.org/W1941861624","https://openalex.org/W1943200861","https://openalex.org/W1945140151","https://openalex.org/W1954377392","https://openalex.org/W1962935964","https://openalex.org/W1965285528","https://openalex.org/W1966647036","https://openalex.org/W1967279745","https://openalex.org/W1967512553","https://openalex.org/W1967629384","https://openalex.org/W1968418992","https://openalex.org/W1969989200","https://openalex.org/W1971118360","https://openalex.org/W1971999946","https://openalex.org/W1972379535","https://openalex.org/W1972424096","https://openalex.org/W1973077654","https://openalex.org/W1973237645","https://openalex.org/W1973944606","https://openalex.org/W1974730258","https://openalex.org/W1974974158","https://openalex.org/W1975009642","https://openalex.org/W1975200587","https://openalex.org/W1975284825","https://openalex.org/W1975388725","https://openalex.org/W1976495499","https://openalex.org/W1977009898","https://openalex.org/W1977600914","https://openalex.org/W1977857319","https://openalex.org/W1978282844","https://openalex.org/W1978684519","https://openalex.org/W1979122474","https://openalex.org/W1979886110","https://openalex.org/W1980358069","https://openalex.org/W1980541542","https://openalex.org/W1980951339","https://openalex.org/W1980985799","https://openalex.org/W1981237781","https://openalex.org/W1981289071","https://openalex.org/W1981546117","https://openalex.org/W1984418452","https://openalex.org/W1985032848","https://openalex.org/W1985501998","https://openalex.org/W1986852320","https://openalex.org/W1986859888","https://openalex.org/W1987229312","https://openalex.org/W1987481358","https://openalex.org/W1987494247","https://openalex.org/W1988143463","https://openalex.org/W1988802259","https://openalex.org/W1988877121","https://openalex.org/W1988924112","https://openalex.org/W1989539426","https://openalex.org/W1990005524","https://openalex.org/W1990595453","https://openalex.org/W1991366780","https://openalex.org/W1991619890","https://openalex.org/W1993025459","https://openalex.org/W1993315944","https://openalex.org/W1993552026","https://openalex.org/W1993690986","https://openalex.org/W1994138655","https://openalex.org/W1994611556","https://openalex.org/W1995744610","https://openalex.org/W1996196835","https://openalex.org/W1996644850","https://openalex.org/W1996839747","https://openalex.org/W1998050886","https://openalex.org/W1998167247","https://openalex.org/W1998583126","https://openalex.org/W1998826672","https://openalex.org/W1999083827","https://openalex.org/W1999236343","https://openalex.org/W1999312002","https://openalex.org/W1999394306","https://openalex.org/W2000302106","https://openalex.org/W2000568970","https://openalex.org/W2000825465","https://openalex.org/W2001352584","https://openalex.org/W2001373277","https://openalex.org/W2002250647","https://openalex.org/W2002611894","https://openalex.org/W2003169826","https://openalex.org/W2003819440","https://openalex.org/W2004313693","https://openalex.org/W2004723561","https://openalex.org/W2005248681","https://openalex.org/W2006221512","https://openalex.org/W2006574739","https://openalex.org/W2006940628","https://openalex.org/W2007252021","https://openalex.org/W2007633562","https://openalex.org/W2008292459","https://openalex.org/W2008767898","https://openalex.org/W2008821667","https://openalex.org/W2008927402","https://openalex.org/W2009106946","https://openalex.org/W2009717200","https://openalex.org/W2011005808","https://openalex.org/W2012483858","https://openalex.org/W2013268035","https://openalex.org/W2013623558","https://openalex.org/W2013627320","https://openalex.org/W2013859761","https://openalex.org/W2013925962","https://openalex.org/W2014903703","https://openalex.org/W2016328321","https://openalex.org/W2016903803","https://openalex.org/W2018157511","https://openalex.org/W2018736745","https://openalex.org/W2019209408","https://openalex.org/W2019532826","https://openalex.org/W2019665740","https://openalex.org/W2020495227","https://openalex.org/W2020563114","https://openalex.org/W2021964673","https://openalex.org/W2022294953","https://openalex.org/W2022754433","https://openalex.org/W2022845057","https://openalex.org/W2023216244","https://openalex.org/W2023464568","https://openalex.org/W2023555072","https://openalex.org/W2023823156","https://openalex.org/W2024372419","https://openalex.org/W2024867274","https://openalex.org/W2025318581","https://openalex.org/W2025700478","https://openalex.org/W2025867450","https://openalex.org/W2026199030","https://openalex.org/W2026325665","https://openalex.org/W2026785948","https://openalex.org/W2027065972","https://openalex.org/W2027789300","https://openalex.org/W2028089693","https://openalex.org/W2028105898","https://openalex.org/W2028676438","https://openalex.org/W2029191095","https://openalex.org/W2029415019","https://openalex.org/W2029533353","https://openalex.org/W2029898126","https://openalex.org/W2030053709","https://openalex.org/W2030284668","https://openalex.org/W2030507620","https://openalex.org/W2030977683","https://openalex.org/W2032140907","https://openalex.org/W2032371793","https://openalex.org/W2032456267","https://openalex.org/W2032494769","https://openalex.org/W2032638458","https://openalex.org/W2034046497","https://openalex.org/W2034999453","https://openalex.org/W2035120304","https://openalex.org/W2036299072","https://openalex.org/W2036550812","https://openalex.org/W2037369436","https://openalex.org/W2037708775","https://openalex.org/W2037984276","https://openalex.org/W2038628152","https://openalex.org/W2039840615","https://openalex.org/W2040456660","https://openalex.org/W2041176514","https://openalex.org/W2041580344","https://openalex.org/W2041584988","https://openalex.org/W2042340425","https://openalex.org/W2042455028","https://openalex.org/W2042630135","https://openalex.org/W2042800640","https://openalex.org/W2043652950","https://openalex.org/W2044710410","https://openalex.org/W2045464339","https://openalex.org/W2045599452","https://openalex.org/W2046482251","https://openalex.org/W2046933775","https://openalex.org/W2049554768","https://openalex.org/W2049911635","https://openalex.org/W2051271931","https://openalex.org/W2051888070","https://openalex.org/W2051901597","https://openalex.org/W2051904771","https://openalex.org/W2053097726","https://openalex.org/W2053150532","https://openalex.org/W2053388585","https://openalex.org/W2053491088","https://openalex.org/W2054710749","https://openalex.org/W2054714399","https://openalex.org/W2055143941","https://openalex.org/W2056258261","https://openalex.org/W2056761299","https://openalex.org/W2057060667","https://openalex.org/W2057360928","https://openalex.org/W2057901567","https://openalex.org/W2058109600","https://openalex.org/W2058420732","https://openalex.org/W2058610272","https://openalex.org/W2058759125","https://openalex.org/W2059135236","https://openalex.org/W2059275312","https://openalex.org/W2060657502","https://openalex.org/W2060971088","https://openalex.org/W2061032018","https://openalex.org/W2061378977","https://openalex.org/W2061980190","https://openalex.org/W2062115516","https://openalex.org/W2062198383","https://openalex.org/W2063270248","https://openalex.org/W2064833161","https://openalex.org/W2065996500","https://openalex.org/W2066465207","https://openalex.org/W2066992082","https://openalex.org/W2067184340","https://openalex.org/W2067412138","https://openalex.org/W2067495470","https://openalex.org/W2067738475","https://openalex.org/W2068891547","https://openalex.org/W2069583796","https://openalex.org/W2070301836","https://openalex.org/W2071124826","https://openalex.org/W2071244034","https://openalex.org/W2072291193","https://openalex.org/W2072351410","https://openalex.org/W2072396130","https://openalex.org/W2072734944","https://openalex.org/W2072855809","https://openalex.org/W2074045859","https://openalex.org/W2074160626","https://openalex.org/W2075737315","https://openalex.org/W2076375837","https://openalex.org/W2077201251","https://openalex.org/W2077647756","https://openalex.org/W2077756191","https://openalex.org/W2077794554","https://openalex.org/W2077890102","https://openalex.org/W2078043484","https://openalex.org/W2078335108","https://openalex.org/W2078472811","https://openalex.org/W2078600385","https://openalex.org/W2079020530","https://openalex.org/W2079080580","https://openalex.org/W2079230824","https://openalex.org/W2079378050","https://openalex.org/W2080350725","https://openalex.org/W2081246578","https://openalex.org/W2081747125","https://openalex.org/W2083331590","https://openalex.org/W2083516615","https://openalex.org/W2084566407","https://openalex.org/W2085260744","https://openalex.org/W2085301617","https://openalex.org/W2086099113","https://openalex.org/W2086437482","https://openalex.org/W2086459386","https://openalex.org/W2086685655","https://openalex.org/W2086790252","https://openalex.org/W2087115130","https://openalex.org/W2087264367","https://openalex.org/W2087318414","https://openalex.org/W2087928272","https://openalex.org/W2088364769","https://openalex.org/W2088629264","https://openalex.org/W2088717034","https://openalex.org/W2089036448","https://openalex.org/W2089100905","https://openalex.org/W2089321175","https://openalex.org/W2089855176","https://openalex.org/W2089965961","https://openalex.org/W2090253137","https://openalex.org/W2090439188","https://openalex.org/W2090481389","https://openalex.org/W2090744550","https://openalex.org/W2090912192","https://openalex.org/W2091456991","https://openalex.org/W2091940311","https://openalex.org/W2092167363","https://openalex.org/W2092512375","https://openalex.org/W2092515735","https://openalex.org/W2093578572","https://openalex.org/W2094337384","https://openalex.org/W2095024948","https://openalex.org/W2095555940","https://openalex.org/W2095912834","https://openalex.org/W2098230404","https://openalex.org/W2099187662","https://openalex.org/W2099286764","https://openalex.org/W2099380050","https://openalex.org/W2100649229","https://openalex.org/W2100797984","https://openalex.org/W2102023134","https://openalex.org/W2102053893","https://openalex.org/W2102618353","https://openalex.org/W2103010344","https://openalex.org/W2103739377","https://openalex.org/W2103951395","https://openalex.org/W2103961074","https://openalex.org/W2104982697","https://openalex.org/W2105812305","https://openalex.org/W2105935520","https://openalex.org/W2106363644","https://openalex.org/W2106624438","https://openalex.org/W2107104127","https://openalex.org/W2108282128","https://openalex.org/W2108363649","https://openalex.org/W2108418875","https://openalex.org/W2108596755","https://openalex.org/W2109216981","https://openalex.org/W2109706976","https://openalex.org/W2111087545","https://openalex.org/W2111288662","https://openalex.org/W2114613490","https://openalex.org/W2114655998","https://openalex.org/W2115268091","https://openalex.org/W2115477649","https://openalex.org/W2115671819","https://openalex.org/W2115826909","https://openalex.org/W2116649573","https://openalex.org/W2117361714","https://openalex.org/W2117537443","https://openalex.org/W2117539624","https://openalex.org/W2118824504","https://openalex.org/W2121668473","https://openalex.org/W2122143736","https://openalex.org/W2122248435","https://openalex.org/W2122551250","https://openalex.org/W2122772014","https://openalex.org/W2122852774","https://openalex.org/W2123074911","https://openalex.org/W2123273468","https://openalex.org/W2123670288","https://openalex.org/W2123712092","https://openalex.org/W2123937038","https://openalex.org/W2123973590","https://openalex.org/W2124568143","https://openalex.org/W2125389594","https://openalex.org/W2126317966","https://openalex.org/W2127020273","https://openalex.org/W2127265093","https://openalex.org/W2127967616","https://openalex.org/W2129527328","https://openalex.org/W2129643943","https://openalex.org/W2129949205","https://openalex.org/W2130225708","https://openalex.org/W2131044019","https://openalex.org/W2131600626","https://openalex.org/W2131973909","https://openalex.org/W2132365435","https://openalex.org/W2132676123","https://openalex.org/W2133382659","https://openalex.org/W2134507238","https://openalex.org/W2135275958","https://openalex.org/W2135805245","https://openalex.org/W2135813547","https://openalex.org/W2135963023","https://openalex.org/W2135971398","https://openalex.org/W2136579709","https://openalex.org/W2136943950","https://openalex.org/W2137074831","https://openalex.org/W2137419334","https://openalex.org/W2138705025","https://openalex.org/W2138809584","https://openalex.org/W2138825852","https://openalex.org/W2138978161","https://openalex.org/W2139002144","https://openalex.org/W2139189234","https://openalex.org/W2139450675","https://openalex.org/W2139803734","https://openalex.org/W2139867736","https://openalex.org/W2140198358","https://openalex.org/W2140486183","https://openalex.org/W2141492787","https://openalex.org/W2141723796","https://openalex.org/W2141732795","https://openalex.org/W2142133740","https://openalex.org/W2142438877","https://openalex.org/W2142849241","https://openalex.org/W2142955539","https://openalex.org/W2143455325","https://openalex.org/W2143789137","https://openalex.org/W2144538553","https://openalex.org/W2144651778","https://openalex.org/W2144665117","https://openalex.org/W2144786229","https://openalex.org/W2144978193","https://openalex.org/W2145213030","https://openalex.org/W2145710987","https://openalex.org/W2146544786","https://openalex.org/W2147073885","https://openalex.org/W2147271582","https://openalex.org/W2147347287","https://openalex.org/W2147758955","https://openalex.org/W2147779511","https://openalex.org/W2148119611","https://openalex.org/W2148344516","https://openalex.org/W2148766286","https://openalex.org/W2149225499","https://openalex.org/W2149710982","https://openalex.org/W2150421099","https://openalex.org/W2150920523","https://openalex.org/W2151049164","https://openalex.org/W2151613538","https://openalex.org/W2151644819","https://openalex.org/W2153157231","https://openalex.org/W2155456310","https://openalex.org/W2155759352","https://openalex.org/W2157029653","https://openalex.org/W2157152468","https://openalex.org/W2158314747","https://openalex.org/W2158369256","https://openalex.org/W2158718693","https://openalex.org/W2159036864","https://openalex.org/W2159833666","https://openalex.org/W2160085646","https://openalex.org/W2160647021","https://openalex.org/W2160957374","https://openalex.org/W2161793782","https://openalex.org/W2164082439","https://openalex.org/W2164280695","https://openalex.org/W2165360151","https://openalex.org/W2165608495","https://openalex.org/W2165645973","https://openalex.org/W2165737281","https://openalex.org/W2166762863","https://openalex.org/W2166840629","https://openalex.org/W2167218265","https://openalex.org/W2168526937","https://openalex.org/W2169044812","https://openalex.org/W2169786466","https://openalex.org/W2170028724","https://openalex.org/W2170754594","https://openalex.org/W2175504413","https://openalex.org/W2185295959","https://openalex.org/W2192223169","https://openalex.org/W2239384431","https://openalex.org/W2247640027","https://openalex.org/W2256917183","https://openalex.org/W2273510741","https://openalex.org/W2282145689","https://openalex.org/W2290691325","https://openalex.org/W2315929780","https://openalex.org/W2322802533","https://openalex.org/W2324841714","https://openalex.org/W2330012690","https://openalex.org/W2333641169","https://openalex.org/W2336425450","https://openalex.org/W2352387075","https://openalex.org/W2391176442","https://openalex.org/W2397114017","https://openalex.org/W2414929403","https://openalex.org/W2416309522","https://openalex.org/W2417352060","https://openalex.org/W2419194999","https://openalex.org/W2420924697","https://openalex.org/W2430143578","https://openalex.org/W2735928575","https://openalex.org/W2790360897","https://openalex.org/W3003425499","https://openalex.org/W3027895630"],"related_works":["https://openalex.org/W2145692767","https://openalex.org/W2160561631","https://openalex.org/W2349922588","https://openalex.org/W2376695000","https://openalex.org/W2947326489","https://openalex.org/W1991742012","https://openalex.org/W2023212009","https://openalex.org/W3147540203","https://openalex.org/W78205198","https://openalex.org/W2372522171"],"abstract_inverted_index":{"Previous":[0],"studies":[1],"have":[2],"shown":[3],"that":[4,103,164,200],"Eicosapentaenoic":[5],"Acid":[6,10,49,138,144],"(EPA)":[7],"and":[8,19,31,71,113,136,146,156,166,221],"Docosahexaenoic":[9],"(DHA)":[11],"exhibit":[12],"triacylglycerol":[13],"(TAG)":[14],"lowering":[15],"effect":[16,46,83,203],"in":[17,20,64,91,93,119,150,170],"vitro":[18,94],"vivo":[21],"by":[22],"down-regulating":[23],"the":[24,33,45,82,120,151,171,181,192,201,211],"Sterol":[25],"Regulating":[26],"Element":[27],"Binding":[28],"Protein":[29],"(SREBP-1c)":[30],"reducing":[32],"expression":[34,53,122,189,208],"levels":[35,123,153,209],"of":[36,47,73,84,124,154,177,191,204,210],"lipogenic":[37,193,212],"genes.":[38],"However,":[39],"there":[40],"is":[41,56],"no":[42],"evidence":[43],"on":[44,51,86,206],"Docosapentaenoic":[48],"(DPA)":[50],"SREBP-1c":[52],"levels.":[54],"DPA":[55,85,104,165,205,219],"a":[57,116,148],"long":[58],"chain":[59],"n-3":[60],"fatty":[61,88,160],"acid":[62,89,161],"present":[63],"our":[65],"diet":[66],"through":[67],"fish,":[68],"red":[69],"meat":[70],"milk":[72],"ruminant":[74],"animals.":[75],"Therefore,":[76],"this":[77],"study":[78],"aimed":[79],"to":[80,218,224],"elucidate":[81],"liver":[87,98],"synthesis":[90],"an":[92],"model":[95],"using":[96],"rat":[97],"cells.":[99],"Our":[100],"results":[101],"suggested":[102],"incubation":[105,178],"(50":[106],"mM)":[107],"for":[108],"48":[109],"h":[110,176,198],"(like":[111],"EPA":[112,167],"DHA)":[114],"caused":[115],"significant":[117],"decrease":[118,149],"mRNA":[121,207],"SREBP-1c,":[125],"3-Hydroxy-3Methyl-Glutaryl-Coenzyme":[126],"A":[127,133,158],"reductase":[128],"(HMG-CoA":[129],"reductase),":[130],"Acetyl":[131],"Coenzyme":[132],"Carboxylase":[134],"(ACC-1)":[135],"Fatty":[137],"Synthase":[139],"(FASn)":[140],"compared":[141],"with":[142,179],"Oleic":[143],"(OA)":[145],"also":[147],"protein":[152],"SREBP-1":[155],"ACC-1.":[157],"time-course":[159],"analysis":[162],"showed":[163],"are":[168],"interconvertable":[169],"cells;":[172],"however,":[173],"after":[174],"8":[175,197],"DPA,":[180],"cell":[182],"phospholipids":[183],"contained":[184],"mainly":[185],"DPA.":[186],"The":[187],"gene":[188],"profiling":[190],"genes":[194,213],"repeated":[195],"at":[196],"confirmed":[199],"inhibitory":[202],"was":[214],"most":[215],"likely":[216],"due":[217,223],"itself":[220],"not":[222],"its":[225],"conversion":[226],"into":[227],"EPA.":[228],"&":[229],"2011":[230],"Elsevier":[231],"Ltd.":[232],"All":[233],"rights":[234],"reserved.":[235]},"counts_by_year":[{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":21},{"year":2022,"cited_by_count":26},{"year":2021,"cited_by_count":42},{"year":2020,"cited_by_count":31},{"year":2019,"cited_by_count":24},{"year":2018,"cited_by_count":16},{"year":2017,"cited_by_count":17},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":11},{"year":2014,"cited_by_count":8},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":7}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}