{"id":"https://openalex.org/W2188952714","doi":null,"title":"Rodent models of heart failure: an updated review","display_name":"Rodent models of heart failure: an updated review","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2188952714","mag":"2188952714"},"language":"en","primary_location":{"id":"mag:2188952714","doi":null,"is_oa":false,"landing_page_url":"http://repositorio-aberto.up.pt/bitstream/10216/72875/3/8301.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064878620","display_name":"Hern\u00e2ni Monteiro","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Hern\u00e2ni Monteiro","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5064878620"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.7759000062942505,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.7759000062942505,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.11919999867677689,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":0.07919999957084656,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heart-failure","display_name":"heart failure","score":0.996999979019165},{"id":"https://openalex.org/keywords/rodent-models","display_name":"rodent models","score":0.9350000023841858},{"id":"https://openalex.org/keywords/animal-models-of-heart-failure","display_name":"animal models of heart failure","score":0.7960000038146973},{"id":"https://openalex.org/keywords/genetically-engineered-mouse-models","display_name":"genetically engineered mouse models","score":0.7760000228881836},{"id":"https://openalex.org/keywords/heart-failure-with-preserved-ejection-fraction","display_name":"heart failure with preserved ejection fraction","score":0.871999979019165},{"id":"https://openalex.org/keywords/congestive-heart-failure","display_name":"congestive heart failure","score":0.953000009059906},{"id":"https://openalex.org/keywords/myocardial-function","display_name":"myocardial function","score":0.6460000276565552},{"id":"https://openalex.org/keywords/pathophysiology-of-heart-failure","display_name":"heart failure pathophysiology","score":0.7919999957084656},{"id":"https://openalex.org/keywords/translational-research","display_name":"translational research","score":0.6380000114440918}],"concepts":[{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.7811001539230347},{"id":"https://openalex.org/C2778117688","wikidata":"https://www.wikidata.org/wiki/Q264024","display_name":"Animal model","level":2,"score":0.538110077381134},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5110071897506714},{"id":"https://openalex.org/C3019111730","wikidata":"https://www.wikidata.org/wiki/Q159236","display_name":"Genetically engineered","level":3,"score":0.4903395175933838},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.4410456717014313},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.2213951051235199},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.19413867592811584},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.18595600128173828},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2188952714","doi":null,"is_oa":false,"landing_page_url":"http://repositorio-aberto.up.pt/bitstream/10216/72875/3/8301.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":322,"referenced_works":["https://openalex.org/W47453547","https://openalex.org/W111885494","https://openalex.org/W120094593","https://openalex.org/W135043852","https://openalex.org/W173191817","https://openalex.org/W176124711","https://openalex.org/W185697375","https://openalex.org/W195435902","https://openalex.org/W200355954","https://openalex.org/W750868314","https://openalex.org/W1482626390","https://openalex.org/W1533702935","https://openalex.org/W1537667391","https://openalex.org/W1549603309","https://openalex.org/W1586735310","https://openalex.org/W1604252033","https://openalex.org/W1607217644","https://openalex.org/W1754620482","https://openalex.org/W1858389298","https://openalex.org/W1896220440","https://openalex.org/W1905550713","https://openalex.org/W1913748006","https://openalex.org/W1920308062","https://openalex.org/W1967425852","https://openalex.org/W1967800726","https://openalex.org/W1967922846","https://openalex.org/W1969098967","https://openalex.org/W1969362382","https://openalex.org/W1969479372","https://openalex.org/W1970800813","https://openalex.org/W1971284289","https://openalex.org/W1971377957","https://openalex.org/W1972913443","https://openalex.org/W1973403849","https://openalex.org/W1974044017","https://openalex.org/W1974159422","https://openalex.org/W1976907821","https://openalex.org/W1978545009","https://openalex.org/W1981047025","https://openalex.org/W1981694347","https://openalex.org/W1982411138","https://openalex.org/W1984007376","https://openalex.org/W1985292788","https://openalex.org/W1987032880","https://openalex.org/W1987399592","https://openalex.org/W1987413126","https://openalex.org/W1987980762","https://openalex.org/W1988536074","https://openalex.org/W1989463892","https://openalex.org/W1989679097","https://openalex.org/W1991589560","https://openalex.org/W1991605997","https://openalex.org/W1991635641","https://openalex.org/W1991935271","https://openalex.org/W1992248841","https://openalex.org/W1992552002","https://openalex.org/W1993237363","https://openalex.org/W1993420218","https://openalex.org/W1994103758","https://openalex.org/W1994734582","https://openalex.org/W1996423501","https://openalex.org/W1997666894","https://openalex.org/W1998137947","https://openalex.org/W1999207957","https://openalex.org/W1999452262","https://openalex.org/W2000014568","https://openalex.org/W2001965896","https://openalex.org/W2002629623","https://openalex.org/W2002971318","https://openalex.org/W2003001641","https://openalex.org/W2003937760","https://openalex.org/W2004620514","https://openalex.org/W2004958384","https://openalex.org/W2006008619","https://openalex.org/W2006221479","https://openalex.org/W2006767632","https://openalex.org/W2007011346","https://openalex.org/W2007277319","https://openalex.org/W2007424272","https://openalex.org/W2009507281","https://openalex.org/W2009527263","https://openalex.org/W2010319438","https://openalex.org/W2010632028","https://openalex.org/W2010820499","https://openalex.org/W2011574657","https://openalex.org/W2012863777","https://openalex.org/W2013167680","https://openalex.org/W2014268281","https://openalex.org/W2015734123","https://openalex.org/W2016279653","https://openalex.org/W2016892245","https://openalex.org/W2017133833","https://openalex.org/W2018146294","https://openalex.org/W2018385177","https://openalex.org/W2019831571","https://openalex.org/W2020160382","https://openalex.org/W2020594690","https://openalex.org/W2021202201","https://openalex.org/W2021476349","https://openalex.org/W2021497986","https://openalex.org/W2022075597","https://openalex.org/W2022784588","https://openalex.org/W2023226461","https://openalex.org/W2023540223","https://openalex.org/W2023651395","https://openalex.org/W2023928179","https://openalex.org/W2026182775","https://openalex.org/W2029562982","https://openalex.org/W2030317008","https://openalex.org/W2031595603","https://openalex.org/W2031683702","https://openalex.org/W2032783599","https://openalex.org/W2033538830","https://openalex.org/W2033967077","https://openalex.org/W2035192492","https://openalex.org/W2035457896","https://openalex.org/W2036154804","https://openalex.org/W2036352096","https://openalex.org/W2036424054","https://openalex.org/W2036744352","https://openalex.org/W2039426841","https://openalex.org/W2039820898","https://openalex.org/W2041421960","https://openalex.org/W2041963336","https://openalex.org/W2042878974","https://openalex.org/W2043698693","https://openalex.org/W2044101767","https://openalex.org/W2044163427","https://openalex.org/W2044331022","https://openalex.org/W2045143786","https://openalex.org/W2045914318","https://openalex.org/W2046794596","https://openalex.org/W2046822720","https://openalex.org/W2047620295","https://openalex.org/W2048304484","https://openalex.org/W2048867275","https://openalex.org/W2049401019","https://openalex.org/W2050036109","https://openalex.org/W2051182592","https://openalex.org/W2051192888","https://openalex.org/W2051229276","https://openalex.org/W2051450681","https://openalex.org/W2052306269","https://openalex.org/W2052396447","https://openalex.org/W2053291556","https://openalex.org/W2054465223","https://openalex.org/W2055162678","https://openalex.org/W2055809956","https://openalex.org/W2055917628","https://openalex.org/W2058099844","https://openalex.org/W2058279355","https://openalex.org/W2059202808","https://openalex.org/W2059487482","https://openalex.org/W2059769358","https://openalex.org/W2059948260","https://openalex.org/W2061405398","https://openalex.org/W2061986589","https://openalex.org/W2063355998","https://openalex.org/W2063958202","https://openalex.org/W2064801250","https://openalex.org/W2064858030","https://openalex.org/W2065456701","https://openalex.org/W2066207377","https://openalex.org/W2067307545","https://openalex.org/W2068671266","https://openalex.org/W2068785830","https://openalex.org/W2070105800","https://openalex.org/W2070431417","https://openalex.org/W2070647639","https://openalex.org/W2070742041","https://openalex.org/W2071913945","https://openalex.org/W2072149341","https://openalex.org/W2073596876","https://openalex.org/W2074137489","https://openalex.org/W2075791946","https://openalex.org/W2076160664","https://openalex.org/W2076221202","https://openalex.org/W2076911700","https://openalex.org/W2079156477","https://openalex.org/W2080955459","https://openalex.org/W2082201094","https://openalex.org/W2083887563","https://openalex.org/W2084244289","https://openalex.org/W2084510672","https://openalex.org/W2085250186","https://openalex.org/W2087750804","https://openalex.org/W2087994415","https://openalex.org/W2088849231","https://openalex.org/W2089217198","https://openalex.org/W2092572747","https://openalex.org/W2093619128","https://openalex.org/W2095221846","https://openalex.org/W2095241287","https://openalex.org/W2095510876","https://openalex.org/W2095812275","https://openalex.org/W2097216911","https://openalex.org/W2100179155","https://openalex.org/W2101377455","https://openalex.org/W2101919304","https://openalex.org/W2103879047","https://openalex.org/W2104190934","https://openalex.org/W2108297050","https://openalex.org/W2108866738","https://openalex.org/W2110155078","https://openalex.org/W2111416247","https://openalex.org/W2111426313","https://openalex.org/W2112844674","https://openalex.org/W2113934901","https://openalex.org/W2114196012","https://openalex.org/W2114313623","https://openalex.org/W2114931342","https://openalex.org/W2115032762","https://openalex.org/W2115177374","https://openalex.org/W2116320816","https://openalex.org/W2116504158","https://openalex.org/W2117267805","https://openalex.org/W2119238023","https://openalex.org/W2119951665","https://openalex.org/W2120224742","https://openalex.org/W2120237634","https://openalex.org/W2121395579","https://openalex.org/W2122253126","https://openalex.org/W2122411629","https://openalex.org/W2122482665","https://openalex.org/W2123220577","https://openalex.org/W2124075001","https://openalex.org/W2124114189","https://openalex.org/W2124602153","https://openalex.org/W2125387035","https://openalex.org/W2127410615","https://openalex.org/W2129925176","https://openalex.org/W2130086266","https://openalex.org/W2131032991","https://openalex.org/W2132464326","https://openalex.org/W2132688728","https://openalex.org/W2132791522","https://openalex.org/W2132812047","https://openalex.org/W2132968998","https://openalex.org/W2135287165","https://openalex.org/W2135674333","https://openalex.org/W2135707070","https://openalex.org/W2135874575","https://openalex.org/W2136094484","https://openalex.org/W2136098553","https://openalex.org/W2136136986","https://openalex.org/W2136331900","https://openalex.org/W2137323429","https://openalex.org/W2137535407","https://openalex.org/W2138552407","https://openalex.org/W2139186800","https://openalex.org/W2140199727","https://openalex.org/W2140608810","https://openalex.org/W2140909944","https://openalex.org/W2142377849","https://openalex.org/W2142754357","https://openalex.org/W2143756095","https://openalex.org/W2143827483","https://openalex.org/W2145002491","https://openalex.org/W2145174650","https://openalex.org/W2145570802","https://openalex.org/W2146195218","https://openalex.org/W2146624681","https://openalex.org/W2148687709","https://openalex.org/W2149239576","https://openalex.org/W2152658552","https://openalex.org/W2152776328","https://openalex.org/W2152847900","https://openalex.org/W2153321120","https://openalex.org/W2153616813","https://openalex.org/W2154295247","https://openalex.org/W2154720198","https://openalex.org/W2156433522","https://openalex.org/W2156995088","https://openalex.org/W2158800467","https://openalex.org/W2159511438","https://openalex.org/W2159830700","https://openalex.org/W2160257210","https://openalex.org/W2160302801","https://openalex.org/W2161240048","https://openalex.org/W2161568820","https://openalex.org/W2162489885","https://openalex.org/W2162689981","https://openalex.org/W2162820159","https://openalex.org/W2162919259","https://openalex.org/W2163149796","https://openalex.org/W2163324146","https://openalex.org/W2163680613","https://openalex.org/W2164006129","https://openalex.org/W2164285416","https://openalex.org/W2166046118","https://openalex.org/W2166742894","https://openalex.org/W2166894412","https://openalex.org/W2166998646","https://openalex.org/W2167424221","https://openalex.org/W2167689288","https://openalex.org/W2168130961","https://openalex.org/W2168302554","https://openalex.org/W2168398375","https://openalex.org/W2169580681","https://openalex.org/W2169759136","https://openalex.org/W2170359120","https://openalex.org/W2171777264","https://openalex.org/W2181350280","https://openalex.org/W2183819193","https://openalex.org/W2193142133","https://openalex.org/W2235517549","https://openalex.org/W2305908886","https://openalex.org/W2317417871","https://openalex.org/W2358193432","https://openalex.org/W2368710359","https://openalex.org/W2403211344","https://openalex.org/W2404792766","https://openalex.org/W2409301351","https://openalex.org/W2410645229","https://openalex.org/W2411240035","https://openalex.org/W2412568176","https://openalex.org/W2413440384","https://openalex.org/W2416604847","https://openalex.org/W2581076299","https://openalex.org/W2614781785","https://openalex.org/W2748413158","https://openalex.org/W2792980560"],"related_works":["https://openalex.org/W349299737","https://openalex.org/W2135287165","https://openalex.org/W1985849960","https://openalex.org/W2093439407","https://openalex.org/W4311202141","https://openalex.org/W4319317716","https://openalex.org/W3157329906","https://openalex.org/W4286207807","https://openalex.org/W174211506","https://openalex.org/W2391058109"],"abstract_inverted_index":{"Heart":[0],"failure":[1],"(HF)":[2],"is":[3,16,119],"one":[4,100],"of":[5,21,67,74,99,116,129],"the":[6,29,50,65,97,124],"major":[7],"health":[8],"and":[9,13,32,39,41,55,69,76,87,93,96,122,127,139],"economic":[10],"burdens":[11],"worldwide,":[12],"its":[14,44],"prevalence":[15],"continuously":[17],"increasing.":[18],"The":[19,114],"study":[20,28],"HF":[22,68,83,133,149],"requires":[23],"reliable":[24],"animal":[25,61,89],"models":[26,62],"to":[27,42,63,120],"chronic":[30],"changes":[31],"pharma-":[33],"cologic":[34],"interventions":[35],"in":[36],"myocardial":[37],"structure":[38],"function":[40],"follow":[43],"progression":[45],"toward":[46],"HF.":[47],"Indeed,":[48],"during":[49],"past":[51],"40":[52],"years,":[53],"basic":[54],"translational":[56],"scientists":[57],"have":[58],"used":[59,132],"small":[60],"understand":[64],"pathophysiology":[66],"find":[70],"more":[71],"efficient":[72],"ways":[73],"preventing":[75],"man-":[77],"aging":[78],"patients":[79],"suffering":[80],"from":[81],"congestive":[82],"(CHF).":[84],"Each":[85],"species":[86],"each":[88],"model":[90,101],"has":[91],"advantages":[92],"disad-":[94],"vantages,":[95],"choice":[98],"over":[102],"another":[103],"should":[104],"take":[105],"them":[106],"into":[107],"account":[108],"for":[109],"a":[110,144],"good":[111],"experimental":[112],"design.":[113],"aim":[115],"this":[117],"review":[118],"describe":[121],"highlight":[123],"advan-":[125],"tages":[126],"drawbacks":[128],"some":[130],"commonly":[131],"rodents":[134],"models,":[135,142],"including":[136],"both":[137],"non-genetically":[138],"genetically":[140],"engineered":[141],"with":[143],"specific":[145],"subchapter":[146],"concerning":[147],"diastolic":[148],"models.":[150]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
