{"id":"https://openalex.org/W2188912010","doi":"https://doi.org/10.12692/ijb/6.4.118-123","title":"Influence of the CYP1B1 gene polymorphisms and uterine leiomyoma risk in Iranian women","display_name":"Influence of the CYP1B1 gene polymorphisms and uterine leiomyoma risk in Iranian women","publication_year":2015,"publication_date":"2015-02-28","ids":{"openalex":"https://openalex.org/W2188912010","doi":"https://doi.org/10.12692/ijb/6.4.118-123","mag":"2188912010"},"language":"en","primary_location":{"id":"doi:10.12692/ijb/6.4.118-123","doi":"https://doi.org/10.12692/ijb/6.4.118-123","is_oa":false,"landing_page_url":"http://doi.org/10.12692/ijb/6.4.118-123","pdf_url":null,"source":{"id":"https://openalex.org/S4210228880","display_name":"International Journal of Biosciences (IJB)","issn_l":"2220-6655","issn":["2220-6655","2222-5234"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Biosciences (IJB)","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5150063056","display_name":"Int J. Biosci","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Int J. Biosci","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161066910","display_name":"Mojdeh Sedighi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mojdeh Sedighi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161115585","display_name":"Shima Karimnejad","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shima Karimnejad","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160991690","display_name":"Batol Farhadi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Batol Farhadi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161053156","display_name":"Morteza Hashemzadeh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Morteza Hashemzadeh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100670343","display_name":"Masoud Amiri","orcid":"https://orcid.org/0000-0002-5145-4833","observed_orcids":["https://orcid.org/0000-0002-5145-4833"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Masoud Amiri","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5069154330","display_name":"Sepideh Miraj","orcid":"https://orcid.org/0000-0002-0012-4527","observed_orcids":["https://orcid.org/0000-0002-0012-4527"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sepideh Miraj","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.15670342,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"6","issue":"4","first_page":"118","last_page":"123"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10989","display_name":"Uterine Myomas and Treatments","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10989","display_name":"Uterine Myomas and Treatments","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1310","display_name":"Endocrinology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/uterine-fibroids","display_name":"uterine fibroids","score":0.9639999866485596},{"id":"https://openalex.org/keywords/cyp1b1","display_name":"CYP1B1","score":0.9710000157356262},{"id":"https://openalex.org/keywords/genetic-polymorphism","display_name":"genetic polymorphism","score":0.8870000243186951},{"id":"https://openalex.org/keywords/genetic-susceptibility","display_name":"genetic susceptibility","score":0.9800000190734863},{"id":"https://openalex.org/keywords/premenopausal-women","display_name":"premenopausal women","score":0.8669999837875366},{"id":"https://openalex.org/keywords/iranian-women","display_name":"Iranian women","score":0.9700000286102295}],"concepts":[{"id":"https://openalex.org/C3017725331","wikidata":"https://www.wikidata.org/wiki/Q556281","display_name":"Uterine leiomyoma","level":3,"score":0.8398575186729431},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.7992292642593384},{"id":"https://openalex.org/C2777795800","wikidata":"https://www.wikidata.org/wiki/Q4667534","display_name":"Leiomyoma","level":2,"score":0.6199688911437988},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.6100183725357056},{"id":"https://openalex.org/C155701950","wikidata":"https://www.wikidata.org/wiki/Q14905165","display_name":"CYP1B1","level":4,"score":0.5999899506568909},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.5697373747825623},{"id":"https://openalex.org/C37463918","wikidata":"https://www.wikidata.org/wiki/Q387981","display_name":"Allele frequency","level":4,"score":0.5197853446006775},{"id":"https://openalex.org/C146304588","wikidata":"https://www.wikidata.org/wiki/Q961652","display_name":"Case-control study","level":2,"score":0.5091320872306824},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.5058571696281433},{"id":"https://openalex.org/C149737253","wikidata":"https://www.wikidata.org/wiki/Q3240252","display_name":"Polymorphism (computer science)","level":4,"score":0.49927759170532227},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4845832586288452},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.47870850563049316},{"id":"https://openalex.org/C168007829","wikidata":"https://www.wikidata.org/wiki/Q857299","display_name":"Restriction fragment length polymorphism","level":4,"score":0.47055983543395996},{"id":"https://openalex.org/C76252995","wikidata":"https://www.wikidata.org/wiki/Q3395645","display_name":"Gene polymorphism","level":4,"score":0.4693542420864105},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4566792845726013},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.4552553594112396},{"id":"https://openalex.org/C49105822","wikidata":"https://www.wikidata.org/wiki/Q176996","display_name":"Polymerase chain reaction","level":3,"score":0.4370213747024536},{"id":"https://openalex.org/C3018023364","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Significant difference","level":2,"score":0.4122897982597351},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3568532466888428},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.32347798347473145},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3109532296657562},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.27336597442626953},{"id":"https://openalex.org/C526171541","wikidata":"https://www.wikidata.org/wiki/Q407693","display_name":"Cytochrome P450","level":3,"score":0.0651913583278656},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.12692/ijb/6.4.118-123","doi":"https://doi.org/10.12692/ijb/6.4.118-123","is_oa":false,"landing_page_url":"http://doi.org/10.12692/ijb/6.4.118-123","pdf_url":null,"source":{"id":"https://openalex.org/S4210228880","display_name":"International Journal of Biosciences (IJB)","issn_l":"2220-6655","issn":["2220-6655","2222-5234"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Biosciences (IJB)","raw_type":"journal-article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.736.8383","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.736.8383","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.innspub.net/wp-content/uploads/2015/03/IJB-V6No4-p118-123.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1604866531","https://openalex.org/W1646169967","https://openalex.org/W1963487709","https://openalex.org/W1970205798","https://openalex.org/W1977660995","https://openalex.org/W1980883029","https://openalex.org/W1982087405","https://openalex.org/W2007822731","https://openalex.org/W2013978980","https://openalex.org/W2020226978","https://openalex.org/W2025204070","https://openalex.org/W2028614333","https://openalex.org/W2044540929","https://openalex.org/W2047374996","https://openalex.org/W2052528439","https://openalex.org/W2081850327","https://openalex.org/W2088018702","https://openalex.org/W2093612217","https://openalex.org/W2100690704","https://openalex.org/W2121662909","https://openalex.org/W2146886004","https://openalex.org/W2151765685","https://openalex.org/W2153265041","https://openalex.org/W2164116103","https://openalex.org/W2264069562","https://openalex.org/W2325845762"],"related_works":["https://openalex.org/W1996365724","https://openalex.org/W2098418016","https://openalex.org/W1995381569","https://openalex.org/W2020226978","https://openalex.org/W7099602903","https://openalex.org/W2340408005","https://openalex.org/W2473403964","https://openalex.org/W2182912749","https://openalex.org/W2938231131","https://openalex.org/W2348708111"],"abstract_inverted_index":{"Uterine":[0],"leiomyoma":[1,30],"(UL)":[2],"is":[3],"the":[4,23,72,77,82,105,113],"most":[5],"common":[6],"gynecological":[7],"benign":[8],"tumor":[9],"with":[10,28,57],"unknown":[11],"etiology":[12],"and":[13,39,61,109],"pathogenesis.":[14],"This":[15],"case-":[16],"control":[17],"study":[18],"was":[19,69,102],"performed":[20],"to":[21,130],"investigate":[22],"association":[24],"between":[25,81,112],"CYP1B1gene":[26],"polymorphisms":[27,111],"uterine":[29],"in":[31,53,128,132],"Iranian":[32,133],"women.":[33,134],"Polymorphisms":[34],"CYP1B1":[35,106,121],"Arg48Gly,":[36,107],"Ala119Ser,":[37],"Leu432Val":[38,78,122],"Asp449Asp":[40,110],"were":[41],"genotyped":[42],"by":[43],"using":[44],"polymerase":[45],"chain":[46],"reaction\u2013restriction":[47],"fragment":[48],"length":[49],"polymorphism":[50,80],"(PCR-RFLP)":[51],"method":[52],"300":[54],"premenopausal":[55],"women":[56],"diagnosed":[58],"UL":[59,131],"(cases)":[60],"200":[62],"healthy":[63],"normal":[64],"(controls).":[65],"A":[66],"significant":[67,100],"difference":[68,101],"found":[70,103],"for":[71,104],"C":[73],"allele":[74],"frequencies":[75],"of":[76],"C>G":[79],"two":[83,114],"groups":[84,115],"(OR":[85],"=":[86,89,94],"0.71,":[87],"P":[88],"0.04,":[90],"95":[91],"%":[92],"CI":[93],"0.48":[95],"\u2013":[96],"1.03).":[97],"However,":[98],"no":[99],"Ala119Ser":[108],"(p>0.05).":[116],"Our":[117],"findings":[118],"indicated":[119],"that":[120],"CC":[123],"genotype":[124],"may":[125],"be":[126],"involved":[127],"susceptibility":[129]},"counts_by_year":[{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}