{"id":"https://openalex.org/W2188846409","doi":null,"title":"[Evaluation of usefulness of urinary nuclear matrix protein 22 (NMP22) in the detection of urothelial transitional cell carcinoma].","display_name":"[Evaluation of usefulness of urinary nuclear matrix protein 22 (NMP22) in the detection of urothelial transitional cell carcinoma].","publication_year":2001,"publication_date":"2001-06-01","ids":{"openalex":"https://openalex.org/W2188846409","mag":"2188846409","pmid":"https://pubmed.ncbi.nlm.nih.gov/11496392"},"language":"ja","primary_location":{"id":"pmid:11496392","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11496392","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hinyokika kiyo. Acta urologica Japonica","raw_type":"Clinical Trial"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071189878","display_name":"Yasuo Miyoshi","orcid":"https://orcid.org/0000-0001-8535-4008","observed_orcids":["https://orcid.org/0000-0001-8535-4008"]},"institutions":[{"id":"https://openalex.org/I4387152949","display_name":"Kanagawa Cancer Center","ror":"https://ror.org/00aapa202","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4387152949"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Y Miyoshi","raw_affiliation_strings":["Department of Urology, Kanagawa Cancer Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Kanagawa Cancer Center","institution_ids":["https://openalex.org/I4387152949"]}]},{"author_position":"middle","author":{"id":null,"display_name":"J Matsuzaki","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J Matsuzaki","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5101409282","display_name":"Takuya Miura","orcid":"https://orcid.org/0000-0001-9929-9169","observed_orcids":["https://orcid.org/0000-0001-9929-9169"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T Miura","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"47","issue":"6","first_page":"379","last_page":"83"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10458","display_name":"Bladder and Urothelial Cancer Treatments","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10458","display_name":"Bladder and Urothelial Cancer Treatments","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10279","display_name":"Urinary Bladder and Prostate Research","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12695","display_name":"Urinary and Genital Oncology Studies","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nmp22","display_name":"NMP22","score":0.9200000166893005},{"id":"https://openalex.org/keywords/urine-cytology","display_name":"urine cytology","score":0.9570000171661377},{"id":"https://openalex.org/keywords/tumor-detection","display_name":"tumor detection","score":0.5699999928474426},{"id":"https://openalex.org/keywords/hematuria","display_name":"hematuria","score":0.9259999990463257},{"id":"https://openalex.org/keywords/sensitivity-and-specificity","display_name":"sensitivity and specificity","score":0.8569999933242798},{"id":"https://openalex.org/keywords/tumor-stage","display_name":"tumor stage","score":0.7839999794960022},{"id":"https://openalex.org/keywords/urinary-diversion","display_name":"urinary diversion","score":0.6959999799728394},{"id":"https://openalex.org/keywords/false-positive-results","display_name":"false positives","score":0.7990000247955322}],"concepts":[{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.8192867040634155},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.755124568939209},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7167414426803589},{"id":"https://openalex.org/C2778065480","wikidata":"https://www.wikidata.org/wiki/Q2501186","display_name":"Transitional cell carcinoma","level":4,"score":0.6309940814971924},{"id":"https://openalex.org/C18823058","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cytology","level":2,"score":0.5711126327514648},{"id":"https://openalex.org/C2779762690","wikidata":"https://www.wikidata.org/wiki/Q9382","display_name":"Urinary bladder","level":2,"score":0.5637281537055969},{"id":"https://openalex.org/C2777540882","wikidata":"https://www.wikidata.org/wiki/Q11878994","display_name":"Urothelium","level":3,"score":0.4877096116542816},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.4176560044288635},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.26072078943252563},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.2434026300907135},{"id":"https://openalex.org/C2780352672","wikidata":"https://www.wikidata.org/wiki/Q504775","display_name":"Bladder cancer","level":3,"score":0.19890210032463074},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1956716775894165},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0732358992099762},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002295","descriptor_name":"Carcinoma, Transitional Cell","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D003581","descriptor_name":"Cytodiagnosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009687","descriptor_name":"Nuclear Proteins","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true},{"descriptor_ui":"D014571","descriptor_name":"Urologic Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:11496392","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11496392","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hinyokika kiyo. Acta urologica Japonica","raw_type":"Clinical Trial"},{"id":"mag:2188846409","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11496392","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9922999739646912,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":3,"referenced_works":["https://openalex.org/W1982131415","https://openalex.org/W2006069963","https://openalex.org/W2093197634"],"related_works":["https://openalex.org/W7146333114","https://openalex.org/W2357982072","https://openalex.org/W7062917909","https://openalex.org/W1838298936","https://openalex.org/W7073763671","https://openalex.org/W2082031299","https://openalex.org/W2273815480","https://openalex.org/W2279476366","https://openalex.org/W2439044160","https://openalex.org/W2377165814"],"abstract_inverted_index":{"We":[0],"evaluated":[1],"the":[2,16,54,61,69,99,142],"usefulness":[3,128],"of":[4,18,33,68,131,144],"urinary":[5,13,47,57,73,84,96,102,111,117,136,151],"nuclear":[6],"matrix":[7],"protein":[8],"22":[9],"(NMP22)":[10],"compared":[11,59],"to":[12,60,150],"cytology":[14,85],"in":[15,53,98],"detection":[17,130,143],"urothelial":[19,44,132],"transitional":[20],"cell":[21],"carcinoma":[22],"(TCC).":[23],"Between":[24],"July":[25],"1999":[26],"and":[27,66,77,80,88,114],"March":[28],"2000,":[29],"227":[30],"patients":[31,41,55,100],"complaining":[32],"microscopic":[34],"or":[35],"gross":[36],"hematuria":[37],"were":[38,75,86,93],"analyzed.":[39],"Twenty-four":[40],"(10.6%)":[42],"had":[43],"TCC.":[45,133],"The":[46,64,116],"NMP22":[48,74,97,118,137],"level":[49,119],"was":[50,120,147],"significantly":[51,121],"higher":[52],"with":[56,72,95,101,123],"TCC":[58],"other":[62,109],"patients.":[63],"sensitivity":[65,140],"specificity":[67],"results":[70,92],"obtained":[71,82,94],"58.3%":[76],"84.2%,":[78],"respectively,":[79],"those":[81],"by":[83],"45.8%":[87],"98.0%,":[89],"respectively.":[90],"False-positive":[91],"diversion":[103],"using":[104],"intestine,":[105],"bladder":[106],"invasion":[107],"from":[108],"cancers,":[110],"tract":[112],"infection,":[113],"urolithiasis.":[115],"associated":[122],"tumor":[124],"stage,":[125],"suggesting":[126],"its":[127],"for":[129,141],"However,":[134],"although":[135],"showed":[138],"equal":[139],"TCC,":[145],"it":[146],"not":[148],"superior":[149],"cytology.":[152]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-11-02T09:45:03.842371","created_date":"2016-06-24T00:00:00"}