{"id":"https://openalex.org/W2188737726","doi":"https://doi.org/10.19026/bjpt.4.5404","title":"Determination of Phytochemical Constituents of the Aqueous Extracts of the Leaves, Stem Bark and Root Bark of Vitex doniana and its Effects on Lipid Profile of Albino Rats","display_name":"Determination of Phytochemical Constituents of the Aqueous Extracts of the Leaves, Stem Bark and Root Bark of Vitex doniana and its Effects on Lipid Profile of Albino Rats","publication_year":2013,"publication_date":"2013-12-25","ids":{"openalex":"https://openalex.org/W2188737726","doi":"https://doi.org/10.19026/bjpt.4.5404","mag":"2188737726"},"language":"en","primary_location":{"id":"doi:10.19026/bjpt.4.5404","doi":"https://doi.org/10.19026/bjpt.4.5404","is_oa":true,"landing_page_url":"https://doi.org/10.19026/bjpt.4.5404","pdf_url":"https://www.maxwellsci.com/announce/BJPT/4-210-214.pdf","source":{"id":"https://openalex.org/S4210199532","display_name":"British Journal of Pharmacology and Toxicology","issn_l":"2044-2459","issn":["2044-2459","2044-2467"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4360969362","host_organization_name":"Maxwell Scientific Publication Corp.","host_organization_lineage":["https://openalex.org/P4360969362"],"host_organization_lineage_names":["Maxwell Scientific Publication Corp."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Pharmacology and Toxicology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.maxwellsci.com/announce/BJPT/4-210-214.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017275131","display_name":"Dorcas Bolanle James","orcid":"https://orcid.org/0000-0002-0732-4740","observed_orcids":["https://orcid.org/0000-0002-0732-4740"]},"institutions":[{"id":"https://openalex.org/I12789410","display_name":"Ahmadu Bello University","ror":"https://ror.org/019apvn83","country_code":"NG","type":"education","lineage":["https://openalex.org/I12789410"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"D.B. James","raw_affiliation_strings":["Department of Biochemistry, Ahmadu Bello University, Samaru Zaria, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Ahmadu Bello University, Samaru Zaria, Nigeria","institution_ids":["https://openalex.org/I12789410"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044714596","display_name":"O.A. Kadejo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I12789410","display_name":"Ahmadu Bello University","ror":"https://ror.org/019apvn83","country_code":"NG","type":"education","lineage":["https://openalex.org/I12789410"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"O.A. Kadejo","raw_affiliation_strings":["Department of Biochemistry, Ahmadu Bello University, Samaru Zaria, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Ahmadu Bello University, Samaru Zaria, Nigeria","institution_ids":["https://openalex.org/I12789410"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010813663","display_name":"C. Nwochiri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I12789410","display_name":"Ahmadu Bello University","ror":"https://ror.org/019apvn83","country_code":"NG","type":"education","lineage":["https://openalex.org/I12789410"]},{"id":"https://openalex.org/I161374704","display_name":"University of Jos","ror":"https://ror.org/009kx9832","country_code":"NG","type":"education","lineage":["https://openalex.org/I161374704"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"C. Nwochiri","raw_affiliation_strings":["Department of Biochemistry, Ahmadu Bello University, Samaru Zaria, Nigeria","Department of Biochemistry, University of Jos, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Ahmadu Bello University, Samaru Zaria, Nigeria","institution_ids":["https://openalex.org/I12789410"]},{"raw_affiliation_string":"Department of Biochemistry, University of Jos, Nigeria","institution_ids":["https://openalex.org/I161374704"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103938378","display_name":"Carlo De Luca","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I12789410","display_name":"Ahmadu Bello University","ror":"https://ror.org/019apvn83","country_code":"NG","type":"education","lineage":["https://openalex.org/I12789410"]},{"id":"https://openalex.org/I161374704","display_name":"University of Jos","ror":"https://ror.org/009kx9832","country_code":"NG","type":"education","lineage":["https://openalex.org/I161374704"]}],"countries":["NG"],"is_corresponding":false,"raw_author_name":"C.D. Luca","raw_affiliation_strings":["Department of Biochemistry, University of Jos, Nigeria","Department of Biochemistry, Ahmadu Bello University, Samaru Zaria, Nigeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Jos, Nigeria","institution_ids":["https://openalex.org/I161374704"]},{"raw_affiliation_string":"Department of Biochemistry, Ahmadu Bello University, Samaru Zaria, Nigeria","institution_ids":["https://openalex.org/I12789410"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3753,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.71675565,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"4","issue":"6","first_page":"210","last_page":"214"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.8949999809265137,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.8949999809265137,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13828","display_name":"Natural Products and Biological Research","score":0.03929999843239784,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12215","display_name":"Phytochemical Studies and Bioactivities","score":0.032099999487400055,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vitex-doniana","display_name":"Vitex doniana","score":1.0},{"id":"https://openalex.org/keywords/phytochemical-screening","display_name":"phytochemical screening","score":0.9359999895095825},{"id":"https://openalex.org/keywords/plant-aqueous-extracts","display_name":"aqueous plant extract","score":0.9290000200271606},{"id":"https://openalex.org/keywords/leaf-extract","display_name":"leaf extract","score":0.7829999923706055},{"id":"https://openalex.org/keywords/stem-bark","display_name":"stem bark","score":0.7900000214576721},{"id":"https://openalex.org/keywords/root-bark","display_name":"root bark","score":1.0},{"id":"https://openalex.org/keywords/lipid-profile","display_name":"lipid profile","score":0.953000009059906},{"id":"https://openalex.org/keywords/saponins","display_name":"saponins","score":0.7699999809265137},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.984000027179718},{"id":"https://openalex.org/keywords/tannins","display_name":"tannins","score":0.8629999756813049},{"id":"https://openalex.org/keywords/cardiac-glycosides","display_name":"cardiac glycosides","score":0.9100000262260437},{"id":"https://openalex.org/keywords/glycosides","display_name":"glycosides","score":0.9369999766349792},{"id":"https://openalex.org/keywords/lipid-lowering-effect","display_name":"hypolipidemic effect","score":0.8100000023841858},{"id":"https://openalex.org/keywords/albino-rats","display_name":"albino rats","score":0.6340000033378601}],"concepts":[{"id":"https://openalex.org/C195475562","wikidata":"https://www.wikidata.org/wiki/Q1639139","display_name":"Phytochemical","level":2,"score":0.8395110368728638},{"id":"https://openalex.org/C133446333","wikidata":"https://www.wikidata.org/wiki/Q38681","display_name":"Bark (sound)","level":2,"score":0.763045072555542},{"id":"https://openalex.org/C194671627","wikidata":"https://www.wikidata.org/wiki/Q192639","display_name":"Glycoside","level":2,"score":0.6280155777931213},{"id":"https://openalex.org/C2778564307","wikidata":"https://www.wikidata.org/wiki/Q207653","display_name":"Saponin","level":3,"score":0.6043485403060913},{"id":"https://openalex.org/C2776055120","wikidata":"https://www.wikidata.org/wiki/Q132607","display_name":"Vitex","level":2,"score":0.5825701355934143},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.5749059915542603},{"id":"https://openalex.org/C2778270857","wikidata":"https://www.wikidata.org/wiki/Q2723972","display_name":"Lipid profile","level":3,"score":0.506154477596283},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.47037380933761597},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.46983903646469116},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.34919607639312744},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2533312141895294},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23392829298973083},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10357698798179626},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.19026/bjpt.4.5404","doi":"https://doi.org/10.19026/bjpt.4.5404","is_oa":true,"landing_page_url":"https://doi.org/10.19026/bjpt.4.5404","pdf_url":"https://www.maxwellsci.com/announce/BJPT/4-210-214.pdf","source":{"id":"https://openalex.org/S4210199532","display_name":"British Journal of Pharmacology and Toxicology","issn_l":"2044-2459","issn":["2044-2459","2044-2467"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4360969362","host_organization_name":"Maxwell Scientific Publication Corp.","host_organization_lineage":["https://openalex.org/P4360969362"],"host_organization_lineage_names":["Maxwell Scientific Publication Corp."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Pharmacology and Toxicology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.19026/bjpt.4.5404","doi":"https://doi.org/10.19026/bjpt.4.5404","is_oa":true,"landing_page_url":"https://doi.org/10.19026/bjpt.4.5404","pdf_url":"https://www.maxwellsci.com/announce/BJPT/4-210-214.pdf","source":{"id":"https://openalex.org/S4210199532","display_name":"British Journal of Pharmacology and Toxicology","issn_l":"2044-2459","issn":["2044-2459","2044-2467"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4360969362","host_organization_name":"Maxwell Scientific Publication Corp.","host_organization_lineage":["https://openalex.org/P4360969362"],"host_organization_lineage_names":["Maxwell Scientific Publication Corp."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"British Journal of Pharmacology and Toxicology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.7246000170707703,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2188737726.pdf","grobid_xml":"https://content.openalex.org/works/W2188737726.grobid-xml"},"referenced_works_count":14,"referenced_works":["https://openalex.org/W2008740070","https://openalex.org/W2016750201","https://openalex.org/W2028727254","https://openalex.org/W2035576567","https://openalex.org/W2042670661","https://openalex.org/W2061142443","https://openalex.org/W2084826880","https://openalex.org/W2107528660","https://openalex.org/W2116404316","https://openalex.org/W2125835545","https://openalex.org/W2162331245","https://openalex.org/W2248490504","https://openalex.org/W4236017105","https://openalex.org/W4254009534"],"related_works":["https://openalex.org/W2087019644","https://openalex.org/W2555440783","https://openalex.org/W610415605","https://openalex.org/W854168215","https://openalex.org/W2062158613","https://openalex.org/W2536544877","https://openalex.org/W2261511108","https://openalex.org/W2363265866","https://openalex.org/W2028217557","https://openalex.org/W1531473896"],"abstract_inverted_index":{"The":[0,69],"phytotochemical":[1],"screening":[2,71],"of":[3,10,28,59,66,72,80,86,105,114,122],"Leaves,":[4],"stem":[5,61,75],"bark":[6,9,62,65,76,79],"and":[7,16,63,77,92],"root":[8,64,78],"Vitex":[11,67,81],"doniana":[12,82],"were":[13,20,53],"carried":[14],"out":[15],"some":[17],"Lipid":[18],"profile":[19],"assessed":[21],"in":[22,102,108],"normal":[23],"albino":[24],"rats":[25,35],"after":[26],"administration":[27,113],"the":[29,73,84,95,103,109,115,120,127],"extracts.":[30,110],"Twenty":[31],"mixed":[32],"sex":[33],"Wistar":[34],"weighing":[36],"150-200":[37],"g":[38],"was":[39],"divided":[40],"into":[41],"4":[42,52],"groups.":[43],"Group":[44],"1":[45],"serves":[46],"as":[47],"control":[48],"while":[49,94],"2,":[50],"3,":[51],"administered":[54],"(100":[55,117],"mg/kg)":[56,118],"aqueous":[57],"extracts":[58,116,128],"leaves,":[60,74],"doniana.":[68],"phytochemical":[70],"shows":[83,124],"presence":[85],"Glycosides,":[87],"Cardiac":[88],"glycosides,":[89],"Saponins,":[90],"Flavonoids":[91],"Tannins":[93],"quantitative":[96],"analysis":[97],"showed":[98],"a":[99],"higher":[100],"value":[101],"amount":[104],"saponin":[106],"present":[107],"Daily":[111],"oral":[112],"for":[119],"period":[121],"21days":[123],"that":[125],"all":[126],"significantly":[129],"(p":[130]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-09-23T09:40:40.371523","created_date":"2025-10-10T00:00:00"}