{"id":"https://openalex.org/W2188660874","doi":null,"title":"Physiological and Pathological Roles for MicroRNAs: Implications for Immunity Complications","display_name":"Physiological and Pathological Roles for MicroRNAs: Implications for Immunity Complications","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2188660874","mag":"2188660874"},"language":"en","primary_location":{"id":"mag:2188660874","doi":null,"is_oa":false,"landing_page_url":"http://ijml.ssu.ac.ir/article-1-31-fa.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063152116","display_name":"Ali Dehghani Firoozabadi","orcid":"https://orcid.org/0000-0002-9406-9505","observed_orcids":["https://orcid.org/0000-0002-9406-9505"]},"institutions":[{"id":"https://openalex.org/I223669574","display_name":"Shahid Sadoughi University of Medical Sciences and Health Services","ror":"https://ror.org/01zby9g91","country_code":"IR","type":"education","lineage":["https://openalex.org/I223669574"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Ali Dehghani Firoozabadi","raw_affiliation_strings":["Yazd Cardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran"],"raw_orcid":"https://orcid.org/0000-0002-9406-9505","affiliations":[{"raw_affiliation_string":"Yazd Cardiovascular Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran","institution_ids":["https://openalex.org/I223669574"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Samaneh Shojaeii","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I86958956","display_name":"Ferdowsi University of Mashhad","ror":"https://ror.org/00g6ka752","country_code":"IR","type":"education","lineage":["https://openalex.org/I86958956"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Samaneh Shojaeii","raw_affiliation_strings":["Department of Biology, Faculty of Science, Ferdowsi University of Mashhad. Mashhad, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Faculty of Science, Ferdowsi University of Mashhad. Mashhad, Iran","institution_ids":["https://openalex.org/I86958956"]}]},{"author_position":"last","author":{"id":null,"display_name":"Hossien Hadinedoushan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223669574","display_name":"Shahid Sadoughi University of Medical Sciences and Health Services","ror":"https://ror.org/01zby9g91","country_code":"IR","type":"education","lineage":["https://openalex.org/I223669574"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Hossien Hadinedoushan","raw_affiliation_strings":["Department of Immunology, Reproductive Immunology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology, Reproductive Immunology Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran","institution_ids":["https://openalex.org/I223669574"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5063152116"],"corresponding_institution_ids":["https://openalex.org/I223669574"],"apc_list":null,"apc_paid":null,"fwci":0.2043,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.49977165,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"1","issue":"1","first_page":"61","last_page":"75"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":1.0},{"id":"https://openalex.org/keywords/autoimmune-disease","display_name":"autoimmune disease","score":0.9319999814033508},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.656000018119812},{"id":"https://openalex.org/keywords/post-transcriptional-regulation","display_name":"post-transcriptional regulation","score":0.921999990940094},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.9120000004768372},{"id":"https://openalex.org/keywords/autoimmunity","display_name":"autoimmunity","score":0.6549999713897705},{"id":"https://openalex.org/keywords/microrna-expression-profiling","display_name":"miRNA expression profiling","score":0.6100000143051147},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.8019999861717224}],"concepts":[{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.8138994574546814},{"id":"https://openalex.org/C2780130043","wikidata":"https://www.wikidata.org/wiki/Q192360","display_name":"Autoimmunity","level":3,"score":0.7228939533233643},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.7092112898826599},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6730642914772034},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.5428696870803833},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.541179358959198},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.5155336856842041},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.4846670925617218},{"id":"https://openalex.org/C2779075594","wikidata":"https://www.wikidata.org/wiki/Q8084905","display_name":"Autoimmune disease","level":3,"score":0.46416833996772766},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.436831533908844},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.43019622564315796},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.4113803505897522},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.252626895904541},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21866640448570251},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.10067421197891235},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.08149588108062744}],"mesh":[],"locations_count":2,"locations":[{"id":"mag:2188660874","doi":null,"is_oa":false,"landing_page_url":"http://ijml.ssu.ac.ir/article-1-31-fa.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"mag:2522011275","doi":null,"is_oa":false,"landing_page_url":"https://ijml.ssu.ac.ir/files/site1/user_files_f703af/admin-A-10-1-8-7921745.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4210206842","display_name":"International Journal of Medical Laboratory","issn_l":"2423-3706","issn":["2423-3706","2423-3714"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319396","host_organization_name":"Knowledge E","host_organization_lineage":["https://openalex.org/P4310319396"],"host_organization_lineage_names":["Knowledge E"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Medical Laboratory","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":97,"referenced_works":["https://openalex.org/W45613634","https://openalex.org/W144423133","https://openalex.org/W1529039901","https://openalex.org/W1562744397","https://openalex.org/W1595490711","https://openalex.org/W1694838020","https://openalex.org/W1799806109","https://openalex.org/W1966624053","https://openalex.org/W1967025862","https://openalex.org/W1972238386","https://openalex.org/W1977745306","https://openalex.org/W1979206745","https://openalex.org/W1980269624","https://openalex.org/W1982024411","https://openalex.org/W1984666548","https://openalex.org/W1985707457","https://openalex.org/W1987917226","https://openalex.org/W1988740302","https://openalex.org/W1990868443","https://openalex.org/W1991320836","https://openalex.org/W1992711646","https://openalex.org/W1994216821","https://openalex.org/W1997329576","https://openalex.org/W1997724110","https://openalex.org/W1998915895","https://openalex.org/W1999319492","https://openalex.org/W2001573429","https://openalex.org/W2006222585","https://openalex.org/W2006831423","https://openalex.org/W2008535165","https://openalex.org/W2009258758","https://openalex.org/W2009901264","https://openalex.org/W2013852511","https://openalex.org/W2014946489","https://openalex.org/W2014974499","https://openalex.org/W2017481656","https://openalex.org/W2023458128","https://openalex.org/W2023869046","https://openalex.org/W2026053005","https://openalex.org/W2027996995","https://openalex.org/W2031143568","https://openalex.org/W2031217896","https://openalex.org/W2033445369","https://openalex.org/W2033459613","https://openalex.org/W2042004955","https://openalex.org/W2047833751","https://openalex.org/W2049772720","https://openalex.org/W2053572539","https://openalex.org/W2058484411","https://openalex.org/W2061664626","https://openalex.org/W2066588601","https://openalex.org/W2069046566","https://openalex.org/W2070017388","https://openalex.org/W2073803015","https://openalex.org/W2074549189","https://openalex.org/W2075860675","https://openalex.org/W2081416658","https://openalex.org/W2082825961","https://openalex.org/W2086809547","https://openalex.org/W2088476840","https://openalex.org/W2094273627","https://openalex.org/W2096388504","https://openalex.org/W2097063436","https://openalex.org/W2098199767","https://openalex.org/W2099706116","https://openalex.org/W2110029925","https://openalex.org/W2114331979","https://openalex.org/W2118343231","https://openalex.org/W2118375123","https://openalex.org/W2119013116","https://openalex.org/W2121126920","https://openalex.org/W2123938528","https://openalex.org/W2124957695","https://openalex.org/W2125945390","https://openalex.org/W2127586500","https://openalex.org/W2127669794","https://openalex.org/W2129038286","https://openalex.org/W2130894316","https://openalex.org/W2136059996","https://openalex.org/W2136068960","https://openalex.org/W2138090246","https://openalex.org/W2138201174","https://openalex.org/W2138664009","https://openalex.org/W2140102579","https://openalex.org/W2143890525","https://openalex.org/W2144893470","https://openalex.org/W2151922790","https://openalex.org/W2152758419","https://openalex.org/W2155898804","https://openalex.org/W2157586673","https://openalex.org/W2157825858","https://openalex.org/W2161425478","https://openalex.org/W2164087707","https://openalex.org/W2166916498","https://openalex.org/W2486559230","https://openalex.org/W2735553444","https://openalex.org/W2742484040"],"related_works":["https://openalex.org/W7096201810","https://openalex.org/W2088476840","https://openalex.org/W1973491685","https://openalex.org/W7096492025","https://openalex.org/W1981155855","https://openalex.org/W2342290396","https://openalex.org/W2149021149","https://openalex.org/W2381021428","https://openalex.org/W1988740302","https://openalex.org/W2011618006"],"abstract_inverted_index":{"MicroRNAs":[0],"(miRNAs)":[1],"are":[2,16],"small":[3],"non-coding":[4],"regulatory":[5,25],"RNAs":[6],"molecules":[7],"with":[8],"a":[9,86],"size":[10],"of":[11,39,43,102,109],"approximately":[12],"22":[13],"nucleotides":[14],"that":[15,70],"implicated":[17],"in":[18,77,89,104],"regulating":[19],"gene":[20],"expression":[21],"at":[22],"the":[23,100,105],"post-transcriptional":[24],"levels.":[26],"Inflammatory":[27],"disorders":[28],"especially":[29],"autoimmune":[30,111],"diseases":[31,82],"(ADs)":[32],"occur":[33],"from":[34],"an":[35],"abnormal":[36],"immune":[37,90],"response":[38,91],"body":[40],"against":[41],"cells":[42],"their":[44],"own":[45],"specific":[46],"tissues":[47],"or":[48],"multiple":[49],"organ":[50],"systems":[51],"leading":[52],"to":[53,62],"chronic":[54],"and":[55,59,79,93,107],"sustain":[56],"inflammatory":[57,81],"responses":[58],"thus":[60],"contribute":[61],"cell":[63],"damage.":[64],"Some":[65],"recent":[66],"studies":[67],"have":[68,85],"reported":[69],"several":[71,110],"miRNAs":[72,103],"may":[73],"be":[74],"expressed":[75],"differentially":[76],"ADs":[78],"other":[80],"which":[83],"can":[84],"critical":[87],"role":[88,101],"modulation":[92],"autoimmunity.":[94],"This":[95],"review":[96],"is":[97],"focused":[98],"on":[99],"pathogenesis":[106],"progression":[108],"diseases.":[112]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}