{"id":"https://openalex.org/W2188494985","doi":null,"title":"Recent Advances in Understanding Carcinogenicity of Oral Squamous Cell Carcinoma: From Basic Molecular Biology to Latest Genomic and Proteomic Findings.","display_name":"Recent Advances in Understanding Carcinogenicity of Oral Squamous Cell Carcinoma: From Basic Molecular Biology to Latest Genomic and Proteomic Findings.","publication_year":2004,"publication_date":"2004-07-01","ids":{"openalex":"https://openalex.org/W2188494985","mag":"2188494985","pmid":"https://pubmed.ncbi.nlm.nih.gov/31394607"},"language":"en","primary_location":{"id":"pmid:31394607","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31394607","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer genomics & proteomics","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054115710","display_name":"Ravi Mehrotra","orcid":"https://orcid.org/0000-0001-9453-1408","observed_orcids":["https://orcid.org/0000-0001-9453-1408"]},"institutions":[{"id":"https://openalex.org/I168893459","display_name":"University of Allahabad","ror":"https://ror.org/03vrx7m55","country_code":"IN","type":"education","lineage":["https://openalex.org/I168893459"]},{"id":"https://openalex.org/I3056136","display_name":"Motilal Nehru Medical College","ror":"https://ror.org/03jmdp146","country_code":"IN","type":"education","lineage":["https://openalex.org/I3056136"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Ravi Mehrotra","raw_affiliation_strings":["Department of Pathology, Moti Lal Nehru Medical College, University of Allahabad, 16/2, Lowther Road, Allahabad-211002, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Moti Lal Nehru Medical College, University of Allahabad, 16/2, Lowther Road, Allahabad-211002, India","institution_ids":["https://openalex.org/I168893459","https://openalex.org/I3056136"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047281940","display_name":"Endre Normann Vasstrand","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4432739","display_name":"University of Bergen","ror":"https://ror.org/03zga2b32","country_code":"NO","type":"education","lineage":["https://openalex.org/I4432739"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Endre Normann Vasstrand","raw_affiliation_strings":["Dental Faculty-Periodontology, University of Bergen, Arstadveien 17, 5009 Bergen"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dental Faculty-Periodontology, University of Bergen, Arstadveien 17, 5009 Bergen","institution_ids":["https://openalex.org/I4432739"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101355584","display_name":"Salah Osman Ibrahim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4432739","display_name":"University of Bergen","ror":"https://ror.org/03zga2b32","country_code":"NO","type":"education","lineage":["https://openalex.org/I4432739"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Salah Osman Ibrahim","raw_affiliation_strings":["Department of Biomedicine, Section of Biochemistry and Molecular Biology, University of Bergen, Jonas Lies Vei 91, 5009 Bergen, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedicine, Section of Biochemistry and Molecular Biology, University of Bergen, Jonas Lies Vei 91, 5009 Bergen, Norway","institution_ids":["https://openalex.org/I4432739"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3899,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.63857849,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"1","issue":"4","first_page":"283","last_page":"294"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11452","display_name":"Oral Health Pathology and Treatment","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oral-squamous-cell-carcinoma","display_name":"oral squamous cell carcinoma","score":1.0},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"carcinogenesis","score":0.902999997138977},{"id":"https://openalex.org/keywords/molecular-biomarkers","display_name":"molecular biomarkers","score":0.7559999823570251},{"id":"https://openalex.org/keywords/cancer-genomics","display_name":"cancer genomics","score":0.847000002861023},{"id":"https://openalex.org/keywords/tobacco-and-alcohol-use","display_name":"alcohol and tobacco use","score":0.6399999856948853},{"id":"https://openalex.org/keywords/etiology","display_name":"etiology","score":0.6679999828338623},{"id":"https://openalex.org/keywords/signaling-pathways","display_name":"signaling pathways","score":0.7369999885559082},{"id":"https://openalex.org/keywords/tumor-classification","display_name":"tumor classification","score":0.7039999961853027}],"concepts":[{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6105720400810242},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5168655514717102},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.5165630578994751},{"id":"https://openalex.org/C46111723","wikidata":"https://www.wikidata.org/wiki/Q471857","display_name":"Proteomics","level":3,"score":0.513127863407135},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.46672549843788147},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.40672481060028076},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.4044390022754669},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.36488938331604004},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.33166617155075073},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.24769359827041626},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.17146334052085876},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.16950830817222595},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.14276456832885742}],"mesh":[],"locations_count":2,"locations":[{"id":"pmid:31394607","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31394607","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer genomics & proteomics","raw_type":"Journal Article"},{"id":"mag:2188494985","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31394607","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":74,"referenced_works":["https://openalex.org/W166360991","https://openalex.org/W238668910","https://openalex.org/W271570111","https://openalex.org/W1482809148","https://openalex.org/W1500427884","https://openalex.org/W1552426876","https://openalex.org/W1573307804","https://openalex.org/W1819302943","https://openalex.org/W1823994930","https://openalex.org/W1965874670","https://openalex.org/W1973773835","https://openalex.org/W1974582859","https://openalex.org/W1978793149","https://openalex.org/W1980229989","https://openalex.org/W1984248172","https://openalex.org/W1989566285","https://openalex.org/W1991174524","https://openalex.org/W1991494214","https://openalex.org/W1991501966","https://openalex.org/W1992666472","https://openalex.org/W1994060558","https://openalex.org/W1997215876","https://openalex.org/W1999748460","https://openalex.org/W2001480633","https://openalex.org/W2007042973","https://openalex.org/W2010614361","https://openalex.org/W2016946646","https://openalex.org/W2025872333","https://openalex.org/W2029253199","https://openalex.org/W2036615276","https://openalex.org/W2036672802","https://openalex.org/W2047156246","https://openalex.org/W2049424656","https://openalex.org/W2050937592","https://openalex.org/W2051143564","https://openalex.org/W2059072983","https://openalex.org/W2060302602","https://openalex.org/W2060498325","https://openalex.org/W2061455950","https://openalex.org/W2062119404","https://openalex.org/W2066202207","https://openalex.org/W2070090934","https://openalex.org/W2073576377","https://openalex.org/W2083750858","https://openalex.org/W2084475506","https://openalex.org/W2085317185","https://openalex.org/W2086698289","https://openalex.org/W2090900427","https://openalex.org/W2091270781","https://openalex.org/W2092378183","https://openalex.org/W2092585633","https://openalex.org/W2097463865","https://openalex.org/W2100669379","https://openalex.org/W2101212813","https://openalex.org/W2113104785","https://openalex.org/W2113541178","https://openalex.org/W2114160852","https://openalex.org/W2114578349","https://openalex.org/W2115372159","https://openalex.org/W2123416081","https://openalex.org/W2127230663","https://openalex.org/W2137884121","https://openalex.org/W2138178697","https://openalex.org/W2146216596","https://openalex.org/W2150048971","https://openalex.org/W2168909179","https://openalex.org/W2170718479","https://openalex.org/W2188359579","https://openalex.org/W2316326259","https://openalex.org/W2398710775","https://openalex.org/W2407861721","https://openalex.org/W2434457919","https://openalex.org/W2804842145","https://openalex.org/W7115593218"],"related_works":["https://openalex.org/W2041968747","https://openalex.org/W2176831718","https://openalex.org/W1968026652","https://openalex.org/W4406079815","https://openalex.org/W2080702512","https://openalex.org/W4285247244","https://openalex.org/W2009075029","https://openalex.org/W6992887785","https://openalex.org/W7009365158","https://openalex.org/W2045412230"],"abstract_inverted_index":{"The":[0],"global":[1],"increase":[2],"in":[3,22,39,58,70,84,167],"incidence":[4],"and":[5,27,47,60,72,87,103,124,163,165],"mortality,":[6],"as":[7,9],"well":[8],"the":[10,23,50,64,73,108,148,155],"poor":[11],"prognosis":[12],"of":[13,25,30,35,44,52,67,110,128,136,141,144],"oral":[14],"squamous":[15],"cell":[16],"carcinoma":[17],"(OSCC),":[18],"has":[19],"intensified":[20],"efforts":[21],"field":[24],"prevention":[26],"early":[28,105],"detection":[29],"this":[31,53,114],"disfiguring":[32],"disease.":[33,126],"Prevalence":[34],"OSCC":[36,92],"is":[37,63,79,146],"common":[38],"areas":[40],"with":[41],"high":[42],"consumption":[43],"tobacco":[45],"products":[46],"alcohol.":[48],"Understanding":[49],"carcinogenicity":[51],"cancer,":[54,121],"using":[55],"innovative":[56],"techniques":[57,89,132],"genomic":[59],"proteomic":[61],"analysis,":[62],"main":[65],"focus":[66],"current":[68],"research":[69],"OSCC,":[71],"hunt":[74],"for":[75,119,133],"potential":[76,142],"molecular":[77,96,130,161],"biomarkers":[78],"accelerating.":[80],"Although":[81],"recent":[82],"advances":[83],"preventive,":[85],"diagnostic":[86],"therapeutic":[88],"related":[90],"to":[91,113,169],"have":[93],"yielded":[94],"novel":[95],"targets,":[97],"partially":[98],"uncovered":[99],"signal":[100],"pathway":[101],"dominance":[102],"advanced":[104,129],"neoplasia":[106],"detection,":[107],"number":[109],"deaths":[111],"attributed":[112],"disease":[115],"exceeds":[116],"that":[117],"reported":[118],"cervical":[120],"malignant":[122],"melanoma":[123],"Hodgkin's":[125],"Application":[127],"biology":[131],"classification,":[134],"profiling":[135],"tumour":[137],"tissues":[138],"and/or":[139],"identification":[140],"markers":[143],"OSCCs":[145],"on":[147,158],"rise.":[149],"This":[150],"review":[151],"aims":[152],"at":[153],"outlining":[154],"available":[156],"knowledge":[157],"epidemiology,":[159],"aetiology,":[160],"biology,":[162],"genomics":[164],"proteomics":[166],"relation":[168],"OSCCs.":[170]},"counts_by_year":[{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}
