{"id":"https://openalex.org/W2188449444","doi":"https://doi.org/10.24729/00000558","title":"Molecular Pathological Study on Interstrain Differences in the Skeletal Muscle Lesions between Dysferlin-deficient SJL and A/J Mice","display_name":"Molecular Pathological Study on Interstrain Differences in the Skeletal Muscle Lesions between Dysferlin-deficient SJL and A/J Mice","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W2188449444","doi":"https://doi.org/10.24729/00000558","mag":"2188449444"},"language":"en","primary_location":{"id":"pmh:oai:irdb.nii.ac.jp:01059:0000900444","doi":"https://doi.org/10.24729/00000558","is_oa":true,"landing_page_url":"https://omu.repo.nii.ac.jp/records/565","pdf_url":"https://omu.repo.nii.ac.jp/record/565/files/k1235.pdf","source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"doctoral thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://omu.repo.nii.ac.jp/record/565/files/k1235.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112249135","display_name":"Kinji Kobayashi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Kinji Kobayashi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5112249135"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12400","display_name":"Neurogenetic and Muscular Disorders Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dysferlin-deficiency","display_name":"dysferlin deficiency","score":0.8870000243186951},{"id":"https://openalex.org/keywords/limb-girdle-muscular-dystrophy","display_name":"limb-girdle muscular dystrophy","score":0.8519999980926514},{"id":"https://openalex.org/keywords/skeletal-muscle-injury","display_name":"skeletal muscle injury","score":0.8309999704360962},{"id":"https://openalex.org/keywords/interstrain-differences","display_name":"interstrain differences","score":0.9139999747276306},{"id":"https://openalex.org/keywords/sjl-mice","display_name":"SJL mice","score":0.9649999737739563},{"id":"https://openalex.org/keywords/a-j-mice","display_name":"A/J mice","score":0.9980000257492065},{"id":"https://openalex.org/keywords/muscular-dystrophy","display_name":"muscular dystrophy","score":0.6880000233650208},{"id":"https://openalex.org/keywords/molecular-pathology","display_name":"molecular pathology","score":0.5260000228881836},{"id":"https://openalex.org/keywords/muscle-fiber-degeneration","display_name":"muscle fiber degeneration","score":0.4950000047683716},{"id":"https://openalex.org/keywords/mouse-model","display_name":"mouse model","score":0.3089999854564667}],"concepts":[{"id":"https://openalex.org/C37113945","wikidata":"https://www.wikidata.org/wiki/Q14885337","display_name":"Dysferlin","level":3,"score":0.8641622066497803},{"id":"https://openalex.org/C2779959927","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Skeletal muscle","level":2,"score":0.6652427911758423},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.5908746123313904},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.42894458770751953},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3515636622905731},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.3255423307418823}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:irdb.nii.ac.jp:01059:0000900444","doi":"https://doi.org/10.24729/00000558","is_oa":true,"landing_page_url":"https://omu.repo.nii.ac.jp/records/565","pdf_url":"https://omu.repo.nii.ac.jp/record/565/files/k1235.pdf","source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"doctoral thesis"},{"id":"mag:2188449444","doi":null,"is_oa":false,"landing_page_url":"http://repository.osakafu-u.ac.jp/dspace/bitstream/10466/10406/1/2010900006.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"mag:2352576046","doi":null,"is_oa":false,"landing_page_url":"http://ci.nii.ac.jp/naid/500000510221?l=ja","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:irdb.nii.ac.jp:01059:0000900444","doi":"https://doi.org/10.24729/00000558","is_oa":true,"landing_page_url":"https://omu.repo.nii.ac.jp/records/565","pdf_url":"https://omu.repo.nii.ac.jp/record/565/files/k1235.pdf","source":{"id":"https://openalex.org/S7407056385","display_name":"Institutional Repositories DataBase (IRDB)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I184597095","host_organization_name":"National Institute of Informatics","host_organization_lineage":["https://openalex.org/I184597095"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"doctoral thesis"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320327566","display_name":"Mitsubishi Tanabe Pharma Corporation","ror":"https://ror.org/038ehsm73"},{"id":"https://openalex.org/F4320336503","display_name":"School of Life and Environmental Sciences, Deakin University","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2188449444.pdf","grobid_xml":"https://content.openalex.org/works/W2188449444.grobid-xml"},"referenced_works_count":63,"referenced_works":["https://openalex.org/W2367701","https://openalex.org/W1546118090","https://openalex.org/W1551392207","https://openalex.org/W1557990274","https://openalex.org/W1772894161","https://openalex.org/W1818696466","https://openalex.org/W1874895667","https://openalex.org/W1967957095","https://openalex.org/W1969205297","https://openalex.org/W1970090817","https://openalex.org/W1973410416","https://openalex.org/W1977421049","https://openalex.org/W1979572992","https://openalex.org/W1981507632","https://openalex.org/W1982268478","https://openalex.org/W1983625376","https://openalex.org/W1988482079","https://openalex.org/W1992220071","https://openalex.org/W1992604276","https://openalex.org/W1994513923","https://openalex.org/W1996100466","https://openalex.org/W1997049749","https://openalex.org/W1998883208","https://openalex.org/W2005366749","https://openalex.org/W2019826234","https://openalex.org/W2020068349","https://openalex.org/W2023397454","https://openalex.org/W2024475665","https://openalex.org/W2026024868","https://openalex.org/W2028603831","https://openalex.org/W2037243869","https://openalex.org/W2038996595","https://openalex.org/W2039745340","https://openalex.org/W2042450333","https://openalex.org/W2051025707","https://openalex.org/W2051702381","https://openalex.org/W2052034388","https://openalex.org/W2054885202","https://openalex.org/W2058537437","https://openalex.org/W2061827083","https://openalex.org/W2072330397","https://openalex.org/W2077295583","https://openalex.org/W2080746281","https://openalex.org/W2082690417","https://openalex.org/W2089328676","https://openalex.org/W2092772857","https://openalex.org/W2099194855","https://openalex.org/W2099249565","https://openalex.org/W2102565806","https://openalex.org/W2108244474","https://openalex.org/W2113821057","https://openalex.org/W2119321661","https://openalex.org/W2121781519","https://openalex.org/W2131523552","https://openalex.org/W2133017132","https://openalex.org/W2137392137","https://openalex.org/W2145150576","https://openalex.org/W2154756699","https://openalex.org/W2157599849","https://openalex.org/W2159361003","https://openalex.org/W2165188979","https://openalex.org/W2170722828","https://openalex.org/W2418448546"],"related_works":["https://openalex.org/W1490140359","https://openalex.org/W2084782873","https://openalex.org/W4254626299","https://openalex.org/W2442124751","https://openalex.org/W2361677571","https://openalex.org/W2019725015","https://openalex.org/W3091050743","https://openalex.org/W3207343334","https://openalex.org/W2066870043","https://openalex.org/W2754265268"],"abstract_inverted_index":{"Muscular":[0],"dystrophy":[1,139,151],"is":[2,153],"a":[3,39,154,183,189],"generic":[4],"term":[5],"used":[6],"to":[7,9,38,52,85],"refer":[8],"as":[10,129,214],"hereditary":[11],"muscle":[12,18,21,31,91,155,160],"disorder":[13,156],"characterized":[14],"clinically":[15],"in":[16,25,166,219],"progressive":[17],"weakness":[19,158],"and":[20,23,27,43,143,159,164,179,210],"atrophy,":[22],"histopathologically":[24],"degeneration/necrosis":[26],"regeneration":[28],"of":[29,34,47,54,89,146,170,195,222],"skeletal":[30],"fibers.The":[32],"progression":[33],"disease":[35],"confines":[36],"patients":[37],"wheelchair":[40],"or":[41,64],"ventilator,":[42],"detracts":[44],"from":[45],"quality":[46],"life":[48],"(QOL).Although":[49],"various":[50],"approaches":[51],"therapy":[53,60,67],"muscular":[55,95,98,101,105,108,113,123,136,150,177],"dystrophy,":[56,96,99,102,114,137],"for":[57],"example,":[58],"gene":[59],"including":[61],"exon":[62],"skipping":[63],"cell":[65],"based":[66],"(Arnett":[68],"et":[69,72,75,119,140],"al.,":[70,73,76],"2009;Farini":[71],"2009;Wang":[74],"2009),":[77],"are":[78],"just":[79],"sought,":[80],"the":[81,167,193,196,201,211,220],"standard":[82],"therapies":[83],"remain":[84],"be":[86],"established.This":[87],"group":[88],"inherited":[90],"disorders":[92],"includes":[93],"Duchenne":[94],"Becker":[97],"Emery-Dreifuss":[100],"limb":[103,148,171],"girdle":[104,149],"dystrophies,":[106,124],"distal":[107,130],"dystrophies":[109,178],"(Miyoshi":[110],"myopathy,":[111,116],"tibial":[112],"myofibrillary/desmin-related":[115],"Welander":[117],"myopathy":[118,126,131],"al.),":[120],"Fukuyama/non-Fukuyama":[121],"congenital":[122],"Nonakel":[125],"(also":[127],"known":[128],"with":[132,200],"rimmed":[133],"vacuoles),":[134],"facioscapulohumeral":[135],"myotonic":[138],"al.":[141],"(Cohn":[142],"Campbell,":[144],"2000).Out":[145],"these,":[147],"(LGMD)":[152],"which":[157],"atrophy":[161],"progress":[162],"slowly":[163],"symmetrically":[165],"proximal":[168],"muscles":[169],"girdles.Because":[172],"LGMD":[173,203],"included":[174],"many":[175],"unclassified":[176],"were":[180],"etiologically":[181],"heterogeneous,":[182],"locus-based":[184],"classification":[185],"was":[186],"proposed":[187],"by":[188],"consortium":[190],"meeting":[191],"under":[192],"auspices":[194],"European":[197],"Neuromuscular":[198],"Centre,":[199],"dominant":[202],"loci":[204],"designated":[205],"LGMD1A,":[206],"B,":[207,216],"C,":[208,217],"etc.":[209,218],"recessive":[212],"froms":[213],"LGMD2A,":[215],"order":[221],"their":[223],"identification":[224],"(Bushby,":[225],"1999).":[226]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
