{"id":"https://openalex.org/W218836485","doi":null,"title":"[Dehydroepiandrosterone (DHEA)--structure, clinical importance and the role in human body].","display_name":"[Dehydroepiandrosterone (DHEA)--structure, clinical importance and the role in human body].","publication_year":2001,"publication_date":"2001-01-01","ids":{"openalex":"https://openalex.org/W218836485","mag":"218836485","pmid":"https://pubmed.ncbi.nlm.nih.gov/11875781"},"language":"pl","primary_location":{"id":"pmid:11875781","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11875781","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Postepy higieny i medycyny doswiadczalnej","raw_type":"English Abstract"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067875981","display_name":"Zygmunt Zdrojewicz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I385303915","display_name":"Wroclaw Medical University","ror":"https://ror.org/01qpw1b93","country_code":"PL","type":"education","lineage":["https://openalex.org/I385303915"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Z Zdrojewicz","raw_affiliation_strings":["Katedra i Klinika Endokrynologii i Diabetologii Akademii Medycznej we Wroc\u0142awiu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Katedra i Klinika Endokrynologii i Diabetologii Akademii Medycznej we Wroc\u0142awiu","institution_ids":["https://openalex.org/I385303915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5001130817","display_name":"Beata Ciszko","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B Ciszko","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.02258367,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"55","issue":"6","first_page":"835","last_page":"54"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11146","display_name":"Hormonal and reproductive studies","score":0.9214000105857849,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11146","display_name":"Hormonal and reproductive studies","score":0.9214000105857849,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":0.07400000095367432,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13736","display_name":"Steroid Chemistry and Biochemistry","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dehydroepiandrosterone","display_name":"dehydroepiandrosterone","score":0.996999979019165},{"id":"https://openalex.org/keywords/dhea-sulfate","display_name":"DHEA sulfate","score":0.8859999775886536},{"id":"https://openalex.org/keywords/adrenal-cortex","display_name":"adrenal cortex","score":0.7960000038146973},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.6499999761581421},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.7850000262260437},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.8349999785423279},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.9990000128746033},{"id":"https://openalex.org/keywords/anti-atherogenic-effects","display_name":"antiatherogenic effects","score":0.7329999804496765},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.7720000147819519},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.8479999899864197},{"id":"https://openalex.org/keywords/memory","display_name":"memory","score":0.8989999890327454},{"id":"https://openalex.org/keywords/anticarcinogenic-activity","display_name":"anticarcinogenic activity","score":0.9409999847412109},{"id":"https://openalex.org/keywords/pregnancy-biomarkers","display_name":"pregnancy biomarkers","score":0.7110000252723694}],"concepts":[{"id":"https://openalex.org/C2776992908","wikidata":"https://www.wikidata.org/wiki/Q408376","display_name":"Dehydroepiandrosterone","level":4,"score":0.8796363472938538},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.8616422414779663},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.551340639591217},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.550621747970581},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5016238689422607},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4637364149093628},{"id":"https://openalex.org/C2777911890","wikidata":"https://www.wikidata.org/wiki/Q62614","display_name":"Androgen","level":3,"score":0.1857137680053711}],"mesh":[{"descriptor_ui":"D000305","descriptor_name":"Adrenal Cortex Hormones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D003072","descriptor_name":"Cognition Disorders","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003920","descriptor_name":"Diabetes Mellitus","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D003920","descriptor_name":"Diabetes Mellitus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009140","descriptor_name":"Musculoskeletal Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D009140","descriptor_name":"Musculoskeletal Diseases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D009765","descriptor_name":"Obesity","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019314","descriptor_name":"Dehydroepiandrosterone Sulfate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019314","descriptor_name":"Dehydroepiandrosterone Sulfate","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:11875781","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11875781","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Postepy higieny i medycyny doswiadczalnej","raw_type":"English Abstract"},{"id":"mag:218836485","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11875781","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2460860512","https://openalex.org/W567340657","https://openalex.org/W4250485486","https://openalex.org/W2159342892","https://openalex.org/W2944329329","https://openalex.org/W4385616783","https://openalex.org/W2068126594","https://openalex.org/W4407170257","https://openalex.org/W170667365","https://openalex.org/W1993292496"],"abstract_inverted_index":{"DHEA":[0,96],"and":[1,92,134],"DHEA-S":[2,102],"are":[3,16,30,56,77,84,123,149],"hormones":[4,15,29,76,111],"synthetized":[5],"primarily":[6],"by":[7],"the":[8,21,72,99,118,157,162],"adrenal":[9],"cortex.":[10],"The":[11,25,107],"levels":[12,26,73,108,148],"oh":[13],"this":[14,28,75,110,154],"systematically":[17],"decreased,":[18],"beginning":[19],"from":[20],"fourth":[22],"life":[23],"decade.":[24],"of":[27,36,64,74,95,109,120,127,131],"also":[31,57,104,114],"abberrated":[32],"as":[33,161],"a":[34,115,125],"consequence":[35],"divorce":[37],"systematical":[38],"diseases":[39],"like":[40,89],"cardiovascular":[41],"diseases,":[42,44,88,91],"skeletal":[43],"diabetes":[45],"mellitus":[46],"or":[47],"obesity.":[48],"This":[49],"hormones,":[50],"probably,":[51],"have":[52,103],"antiaheromatic":[53],"facilities.":[54,106],"There":[55,122],"data":[58],"suggesting":[59],"their":[60,141,147],"influence":[61],"on":[62],"stimulation":[63],"immunological":[65],"system.":[66],"It":[67],"is":[68,136],"already":[69],"confirmed":[70],"that":[71,83],"modified":[78],"in":[79,86,143],"congenital":[80],"function":[81],"disorders":[82],"present":[85],"different":[87,132],"Alzheimer":[90],"oral":[93],"administration":[94],"can":[97,112],"improves":[98],"memory.":[100],"Presumably":[101],"anticarcinogenic":[105],"be":[113],"marker":[116],"monitoring":[117],"course":[119],"pregnancy.":[121],"still":[124],"lot":[126],"discrepancies":[128],"between":[129],"results":[130],"studies":[133],"it":[135],"very":[137],"difficult":[138],"to":[139],"describe":[140],"role":[142],"human":[144],"body.":[145],"Because":[146],"decreased":[150],"with":[151],"ageing":[152],"process,":[153],"observation":[155],"makes":[156],"researchers":[158],"call":[159],"them":[160],"\"youth":[163],"hormones\".":[164]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}