{"id":"https://openalex.org/W2188304609","doi":null,"title":"Inhibitory effects of 2-hydroxybenzaldehyde on the activity of phenoloxidase from Pieris rapae (Lepidoptera) larvae","display_name":"Inhibitory effects of 2-hydroxybenzaldehyde on the activity of phenoloxidase from Pieris rapae (Lepidoptera) larvae","publication_year":2008,"publication_date":"2008-06-01","ids":{"openalex":"https://openalex.org/W2188304609","mag":"2188304609"},"language":"en","primary_location":{"id":"mag:2188304609","doi":null,"is_oa":true,"landing_page_url":"http://nopr.niscair.res.in/bitstream/123456789/1931/1/IJBB%2045%283%29%20184-191.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S104480359","display_name":"Indian Journal of Biochemistry and Biophysics","issn_l":"0301-1208","issn":["0301-1208","0975-0959"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310318680","host_organization_name":"NISCAIR","host_organization_lineage":["https://openalex.org/P4310318680","https://openalex.org/P4310318672"],"host_organization_lineage_names":["NISCAIR","Council of Scientific and Industrial Research"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Indian Journal of Biochemistry and Biophysics","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://nopr.niscair.res.in/bitstream/123456789/1931/1/IJBB%2045%283%29%20184-191.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065732495","display_name":"Chao\u2010Bin Xue","orcid":"https://orcid.org/0000-0001-6891-7120","observed_orcids":["https://orcid.org/0000-0001-6891-7120"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chao\u2010Bin Xue","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6891-7120","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112376004","display_name":"Luo Wan-chun","orcid":"https://orcid.org/0009-0006-2449-8765","observed_orcids":["https://orcid.org/0009-0006-2449-8765"]},"institutions":[{"id":"https://openalex.org/I74485261","display_name":"Shandong Agricultural University","ror":"https://ror.org/02ke8fw32","country_code":"CN","type":"education","lineage":["https://openalex.org/I74485261"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Luo Wan-chun","raw_affiliation_strings":["Shandong agricultural University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shandong agricultural University","institution_ids":["https://openalex.org/I74485261"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049049288","display_name":"Qing\u2010Xi Chen","orcid":"https://orcid.org/0000-0001-7845-1571","observed_orcids":["https://orcid.org/0000-0001-7845-1571"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Qing\u2010Xi Chen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041613131","display_name":"MA De-ying","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"MA De-ying","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"Qian Wang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Qian Wang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2496,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.48431318,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"45","issue":"3","first_page":"184","last_page":"191"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10423","display_name":"Neurobiology and Insect Physiology Research","score":0.1860000044107437,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10423","display_name":"Neurobiology and Insect Physiology Research","score":0.1860000044107437,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11747","display_name":"Metal-Catalyzed Oxygenation Mechanisms","score":0.10980000346899033,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11144","display_name":"melanin and skin pigmentation","score":0.09229999780654907,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/phenoloxidase","display_name":"phenoloxidase","score":0.9459999799728394},{"id":"https://openalex.org/keywords/2-hydroxybenzaldehyde","display_name":"2-hydroxybenzaldehyde","score":0.9829999804496765},{"id":"https://openalex.org/keywords/enzyme-inhibition","display_name":"enzyme inhibition","score":0.9079999923706055},{"id":"https://openalex.org/keywords/small-white-butterfly","display_name":"small white butterfly","score":0.8650000095367432},{"id":"https://openalex.org/keywords/caterpillars","display_name":"caterpillars","score":0.7490000128746033},{"id":"https://openalex.org/keywords/monophenolase-activity","display_name":"monophenolase activity","score":0.8970000147819519},{"id":"https://openalex.org/keywords/diphenolase-activity","display_name":"diphenolase activity","score":0.9990000128746033},{"id":"https://openalex.org/keywords/l-tyrosine-oxidation","display_name":"L-tyrosine oxidation","score":0.9879999756813049},{"id":"https://openalex.org/keywords/l-dopa-oxidation","display_name":"L-DOPA oxidation","score":0.9940000176429749},{"id":"https://openalex.org/keywords/enzyme-kinetics","display_name":"enzyme kinetics","score":0.6389999985694885},{"id":"https://openalex.org/keywords/insect-development","display_name":"insect development","score":0.43700000643730164}],"concepts":[{"id":"https://openalex.org/C2777248757","wikidata":"https://www.wikidata.org/wiki/Q27653","display_name":"Pieris rapae","level":3,"score":0.8287135362625122},{"id":"https://openalex.org/C2781109383","wikidata":"https://www.wikidata.org/wiki/Q898497","display_name":"Hydroxylation","level":3,"score":0.7241140007972717},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6252055168151855},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.5817570090293884},{"id":"https://openalex.org/C177756618","wikidata":"https://www.wikidata.org/wiki/Q6527674","display_name":"Lepidoptera genitalia","level":2,"score":0.5786497592926025},{"id":"https://openalex.org/C28212737","wikidata":"https://www.wikidata.org/wiki/Q5381543","display_name":"Enzyme assay","level":3,"score":0.5757662057876587},{"id":"https://openalex.org/C2776165026","wikidata":"https://www.wikidata.org/wiki/Q188017","display_name":"Tyrosine","level":2,"score":0.5408616065979004},{"id":"https://openalex.org/C148898269","wikidata":"https://www.wikidata.org/wiki/Q1108792","display_name":"Kinetics","level":2,"score":0.5078545212745667},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.49931955337524414},{"id":"https://openalex.org/C56856141","wikidata":"https://www.wikidata.org/wiki/Q883112","display_name":"Enzyme kinetics","level":4,"score":0.4867110550403595},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.4844946563243866},{"id":"https://openalex.org/C93391505","wikidata":"https://www.wikidata.org/wiki/Q658700","display_name":"Reaction rate constant","level":3,"score":0.41460299491882324},{"id":"https://openalex.org/C41183919","wikidata":"https://www.wikidata.org/wiki/Q423026","display_name":"Active site","level":3,"score":0.2728212773799896},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2598557472229004},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.19231659173965454},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.18862152099609375},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2188304609","doi":null,"is_oa":true,"landing_page_url":"http://nopr.niscair.res.in/bitstream/123456789/1931/1/IJBB%2045%283%29%20184-191.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S104480359","display_name":"Indian Journal of Biochemistry and Biophysics","issn_l":"0301-1208","issn":["0301-1208","0975-0959"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310318680","host_organization_name":"NISCAIR","host_organization_lineage":["https://openalex.org/P4310318680","https://openalex.org/P4310318672"],"host_organization_lineage_names":["NISCAIR","Council of Scientific and Industrial Research"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Indian Journal of Biochemistry and Biophysics","raw_type":null}],"best_oa_location":{"id":"mag:2188304609","doi":null,"is_oa":true,"landing_page_url":"http://nopr.niscair.res.in/bitstream/123456789/1931/1/IJBB%2045%283%29%20184-191.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S104480359","display_name":"Indian Journal of Biochemistry and Biophysics","issn_l":"0301-1208","issn":["0301-1208","0975-0959"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310318680","host_organization_name":"NISCAIR","host_organization_lineage":["https://openalex.org/P4310318680","https://openalex.org/P4310318672"],"host_organization_lineage_names":["NISCAIR","Council of Scientific and Industrial Research"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Indian Journal of Biochemistry and Biophysics","raw_type":null},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2028363784","https://openalex.org/W2353395383","https://openalex.org/W2021973123","https://openalex.org/W1997639669","https://openalex.org/W2382433562","https://openalex.org/W2393402942","https://openalex.org/W2385966875","https://openalex.org/W2132585785","https://openalex.org/W2382457745","https://openalex.org/W2350647204"],"abstract_inverted_index":{"Phenoloxidase":[0],"(PO)":[1],"is":[2],"a":[3,58,122,175],"key":[4],"enzyme":[5,101,110,159,191],"in":[6,40,47,160],"insect":[7],"development,":[8],"responsible":[9],"for":[10,31,139,146,184],"catalyzing":[11],"the":[12,25,28,48,69,85,100,105,109,150,158,161,168,185,190],"hydroxylation":[13],"of":[14,20,50,65,74,90,95,108,127,134,152,154,163,166,187],"tyrosine":[15],"into":[16,22],"O-diphenols":[17,21],"and":[18,43,54,71,87,104,130,141],"oxidation":[19,49,97,153],"O-quinones.":[23],"In":[24,149],"present":[26],"study,":[27],"kinetic":[29,45],"assay":[30],"PO":[32,75],"from":[33],"Pieris":[34],"rapae":[35],"(L.)":[36],"larvae":[37],"was":[38,60,102,115,178],"performed":[39],"air-saturated":[41],"solutions":[42],"its":[44],"behavior":[46],"L-tyrosine":[51,96],"(a":[52],"monophenol)":[53],"L-DOPA":[55,155],"(L-3,":[56],"4-dihydroxyphenylalanine,":[57],"diphenol)":[59],"studied.":[61,78],"The":[62,92,113,180],"inhibitory":[63],"effects":[64],"2-hydroxybenzaldehyde":[66],"(2-HBD)":[67],"on":[68],"monophenolase":[70,86,140],"diphenolase":[72,88,147],"activities":[73,89],"were":[76,192],"also":[77],"Results":[79],"showed":[80],"that":[81],"2-HBD":[82,188],"inhibit":[83],"both":[84],"PO.":[91],"lag":[93],"period":[94],"catalyzed":[98,156],"by":[99,157],"lengthened":[103],"steady-state":[106],"activity":[107],"sharply":[111],"decreased.":[112],"inhibitor":[114],"found":[116],"to":[117],"be":[118],"noncompetitively":[119],"reversible":[120],"with":[121,171,189],"KI":[123],"(KI":[124],"=":[125],"KIS)":[126],"1.21":[128],"mmol/L":[129,138,145],"an":[131],"estimated":[132],"IC50":[133],"8.08":[135],"\u00b1":[136,143],"0.11":[137],"4.14":[142],"0.08":[144],"activities.":[148],"time-course":[151],"presence":[162],"different":[164],"concentrations":[165],"2-HBD,":[167],"rate":[169,182],"decreased":[170],"increasing":[172],"time":[173],"until":[174],"straight":[176],"line":[177],"reached.":[179],"microscopic":[181],"constants":[183],"reaction":[186],"determined.":[193]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2016-06-24T00:00:00"}