{"id":"https://openalex.org/W2188169649","doi":null,"title":"Formulation and Evaluation of Ocular in Situ Gelling System of Moxifloxacin Hydrochloride","display_name":"Formulation and Evaluation of Ocular in Situ Gelling System of Moxifloxacin Hydrochloride","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2188169649","mag":"2188169649"},"language":"en","primary_location":{"id":"mag:2188169649","doi":null,"is_oa":false,"landing_page_url":"https://www.pharmaresearchlibrary.com/wp-content/uploads/2013/10/PRL2013-JPBMAL-1779.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059074110","display_name":"Anaparthi Sireesha","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anaparthi Sireesha","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017827401","display_name":"K. Arshad","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K. Arshad","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5108937096","display_name":"C. Sowmya","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C. Sowmya","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10997","display_name":"Ocular Surface and Contact Lens","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/moxifloxacin-hydrochloride","display_name":"moxifloxacin hydrochloride","score":0.996999979019165},{"id":"https://openalex.org/keywords/in-situ-gel","display_name":"in situ gel","score":0.8550000190734863},{"id":"https://openalex.org/keywords/ocular-drug-delivery","display_name":"ocular drug delivery","score":0.7689999938011169},{"id":"https://openalex.org/keywords/ph-triggered-gelation","display_name":"pH-triggered gelation","score":0.8360000252723694},{"id":"https://openalex.org/keywords/sodium-alginate","display_name":"sodium alginate","score":0.9959999918937683},{"id":"https://openalex.org/keywords/hydroxypropyl-methylcellulose","display_name":"hydroxypropyl methylcellulose","score":0.9269999861717224},{"id":"https://openalex.org/keywords/benzalkonium-chloride","display_name":"benzalkonium chloride","score":0.9200000166893005},{"id":"https://openalex.org/keywords/sustained-release","display_name":"sustained drug release","score":0.8270000219345093},{"id":"https://openalex.org/keywords/in-vitro-drug-diffusion","display_name":"in vitro drug diffusion","score":0.6669999957084656},{"id":"https://openalex.org/keywords/drug-polymer-compatibility","display_name":"drug-polymer compatibility","score":0.7839999794960022},{"id":"https://openalex.org/keywords/fluoroquinolones","display_name":"fluoroquinolones","score":0.7730000019073486}],"concepts":[{"id":"https://openalex.org/C2778836808","wikidata":"https://www.wikidata.org/wiki/Q424940","display_name":"Moxifloxacin","level":3,"score":0.6226224899291992},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6070747971534729},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5829912424087524},{"id":"https://openalex.org/C67031304","wikidata":"https://www.wikidata.org/wiki/Q274579","display_name":"Preservative","level":2,"score":0.5432549118995667},{"id":"https://openalex.org/C2776460385","wikidata":"https://www.wikidata.org/wiki/Q420060","display_name":"Hydrochloride","level":2,"score":0.4944894313812256},{"id":"https://openalex.org/C2777822432","wikidata":"https://www.wikidata.org/wiki/Q216681","display_name":"In situ","level":2,"score":0.4611852765083313},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.33438587188720703},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.2635161280632019},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.18504777550697327},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13831213116645813},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.11629635095596313}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2188169649","doi":null,"is_oa":false,"landing_page_url":"https://www.pharmaresearchlibrary.com/wp-content/uploads/2013/10/PRL2013-JPBMAL-1779.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W2003761017","https://openalex.org/W2007991128","https://openalex.org/W2030857049","https://openalex.org/W2074208432","https://openalex.org/W2086053592","https://openalex.org/W2185703866"],"related_works":["https://openalex.org/W2182258972","https://openalex.org/W2169634958","https://openalex.org/W2246373414","https://openalex.org/W6893264197","https://openalex.org/W849117291","https://openalex.org/W2090409395","https://openalex.org/W2253625110","https://openalex.org/W2980960875","https://openalex.org/W4391291178","https://openalex.org/W6893452496"],"abstract_inverted_index":{"The":[0,75,97],"aim":[1],"of":[2,107],"the":[3],"current":[4],"study":[5,61,89],"is":[6],"to":[7],"design":[8],"and":[9,73,90,93,114],"chara":[10],"cterize":[11],"pH":[12,84],"triggered":[13],"in":[14,37,125],"situ":[15,126],"ophthalmic":[16,136],"gel":[17],"forming":[18],"solution":[19],"using":[20],"a":[21],"fourth":[22],"gene":[23],"ration":[24],"fluoroquinolone":[25],"antibiotic,":[26],"Moxifloxacin":[27],"hydrochlor":[28],"ide.":[29],"Sodium":[30],"alginate":[31],"was":[32,54,62],"used":[33,55],"as":[34,46,56,132],"gelling":[35,127],"agent":[36],"combination":[38],"with":[39,117],"hydro":[40],"xyl":[41],"propyl":[42],"methyl":[43],"cellulose":[44],"(E15LV)":[45],"viscosifying":[47],"agent.":[48],"Benzalkoni":[49],"um":[50],"ch":[51],"suitable":[52],"concentration":[53],"preservative.":[57],"Dr":[58],"ug":[59],"compatibility":[60],"performed":[63],"by":[64],"FTIR":[65],"studies,":[66],"which":[67],"indicates":[68],"no":[69],"interaction":[70],"among":[71],"drug":[72,91],"polymers.":[74],"prepared":[76],"formulations":[77],"were":[78],"evaluated":[79],"for":[80,103,134],"visual":[81],"appearance,":[82],"clarity,":[83],"measurement,":[85],"viscosity,":[86],"vitro":[87],"gellation":[88],"content":[92],"in-vitro":[94],"diffusion":[95],"studies.":[96],"selected":[98],"formulation":[99],"showed":[100,121],"sustained":[101],"release":[102],"t":[104],"he":[105],"period":[106],"10":[108],"hours":[109],"thus":[110,124],"showing":[111],"increased":[112],"residence":[113],"contact":[115],"time":[116],"eye.":[118],"All":[119],"studies":[120],"favourable":[122],"results":[123],"system":[128],"can":[129],"be":[130],"considered":[131],"alternative":[133],"conventional":[135],"drops.":[137]},"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2025-11-06T04:12:42.849631","created_date":"2016-06-24T00:00:00"}