{"id":"https://openalex.org/W2188064209","doi":null,"title":"Evaluating Human Health Risks from Exposure to Perfluorooctanoic Acid (PFOA): Recommendations to the Science Advisory Board's PFOA Review Panel","display_name":"Evaluating Human Health Risks from Exposure to Perfluorooctanoic Acid (PFOA): Recommendations to the Science Advisory Board's PFOA Review Panel","publication_year":2005,"publication_date":"2005-01-01","ids":{"openalex":"https://openalex.org/W2188064209","mag":"2188064209"},"language":"en","primary_location":{"id":"mag:2188064209","doi":null,"is_oa":false,"landing_page_url":"https://yosemite.epa.gov/sab/sabproduct.nsf/ded77e69fc8ced288525711e006fe16b/$file/kropp-ewg.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038479729","display_name":"Timothy Kropp","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Timothy Kropp","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051462300","display_name":"Toxicologist","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Toxicologist","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5052188204","display_name":"Jane Houlihan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jane Houlihan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9327,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.7233809,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":95},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11869","display_name":"Per- and polyfluoroalkyl substances research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2304","display_name":"Environmental Chemistry"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11869","display_name":"Per- and polyfluoroalkyl substances research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2304","display_name":"Environmental Chemistry"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10122","display_name":"Toxic Organic Pollutants Impact","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/perfluorooctanoic-acid","display_name":"perfluorooctanoic acid","score":0.9990000128746033},{"id":"https://openalex.org/keywords/human-health-risk-assessment","display_name":"human health risk assessment","score":0.9909999966621399},{"id":"https://openalex.org/keywords/lifetime-cancer-risk","display_name":"lifetime cancer risk","score":0.7110000252723694},{"id":"https://openalex.org/keywords/benchmark-dose","display_name":"benchmark dose","score":0.8820000290870667},{"id":"https://openalex.org/keywords/non-cancer-risk-assessment","display_name":"non-cancer risk assessment","score":0.9229999780654907},{"id":"https://openalex.org/keywords/blood-levels","display_name":"blood concentration","score":0.5329999923706055},{"id":"https://openalex.org/keywords/carcinogenicity","display_name":"carcinogenicity","score":0.5370000004768372},{"id":"https://openalex.org/keywords/toxic-equivalents","display_name":"toxic equivalents","score":0.31700000166893005}],"concepts":[{"id":"https://openalex.org/C2775979320","wikidata":"https://www.wikidata.org/wiki/Q418348","display_name":"Perfluorooctanoic acid","level":2,"score":0.9013717174530029},{"id":"https://openalex.org/C12174686","wikidata":"https://www.wikidata.org/wiki/Q1058438","display_name":"Risk assessment","level":2,"score":0.596184253692627},{"id":"https://openalex.org/C2987857752","wikidata":"https://www.wikidata.org/wiki/Q12147","display_name":"Human health","level":2,"score":0.5055372714996338},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4910135567188263},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.47995665669441223},{"id":"https://openalex.org/C108170787","wikidata":"https://www.wikidata.org/wiki/Q3951828","display_name":"Agency (philosophy)","level":2,"score":0.47593143582344055},{"id":"https://openalex.org/C3017489713","wikidata":"https://www.wikidata.org/wiki/Q4686866","display_name":"Advisory committee","level":2,"score":0.47464829683303833},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.10821983218193054},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.10777556896209717},{"id":"https://openalex.org/C107872376","wikidata":"https://www.wikidata.org/wiki/Q321355","display_name":"Environmental chemistry","level":1,"score":0.10596418380737305},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.09529644250869751},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C38652104","wikidata":"https://www.wikidata.org/wiki/Q3510521","display_name":"Computer security","level":1,"score":0.0},{"id":"https://openalex.org/C3116431","wikidata":"https://www.wikidata.org/wiki/Q31728","display_name":"Public administration","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2188064209","doi":null,"is_oa":false,"landing_page_url":"https://yosemite.epa.gov/sab/sabproduct.nsf/ded77e69fc8ced288525711e006fe16b/$file/kropp-ewg.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W1964923030","https://openalex.org/W1972258539","https://openalex.org/W1976770880","https://openalex.org/W1985972532","https://openalex.org/W1996023595","https://openalex.org/W1997309359","https://openalex.org/W1997432183","https://openalex.org/W1999600038","https://openalex.org/W2018652424","https://openalex.org/W2020138408","https://openalex.org/W2024165817","https://openalex.org/W2029596629","https://openalex.org/W2034901755","https://openalex.org/W2035966708","https://openalex.org/W2043748391","https://openalex.org/W2046719094","https://openalex.org/W2057310849","https://openalex.org/W2057662606","https://openalex.org/W2067923517","https://openalex.org/W2068751295","https://openalex.org/W2070530203","https://openalex.org/W2075016249","https://openalex.org/W2076884184","https://openalex.org/W2078553897","https://openalex.org/W2081345559","https://openalex.org/W2088561659","https://openalex.org/W2096576358","https://openalex.org/W2096655617","https://openalex.org/W2097049516","https://openalex.org/W2105954461","https://openalex.org/W2127587781","https://openalex.org/W2165677144","https://openalex.org/W2169545575"],"related_works":["https://openalex.org/W4409722463","https://openalex.org/W4412736474","https://openalex.org/W4380051075","https://openalex.org/W2079469720","https://openalex.org/W2187245822","https://openalex.org/W2094265808","https://openalex.org/W2096655617","https://openalex.org/W2076027583","https://openalex.org/W2169621267","https://openalex.org/W7166470992"],"abstract_inverted_index":{"We":[0,17,50],"also":[1,51,113],"recommend":[2],"an":[3,19],"alternate":[4],"method":[5,27,111],"for":[6,23,28,34,58,79,92,96],"evaluating":[7,29],"human":[8,123],"health":[9,124],"risk":[10,33,60,98],"than":[11],"that":[12,78],"selected":[13,114],"by":[14,63,115],"the":[15,37,64,70,103],"Agency.":[16],"describe":[18,52],"ED10":[20],"(estimated":[21],"dose":[22,84],"10":[24],"percent":[25],"response)":[26],"excess":[30],"lifetime":[31],"cancer":[32],"three":[35],"of":[36,67,105,122],"tumor":[38],"types":[39],"found":[40],"at":[41],"statistically":[42],"significant":[43],"levels":[44,99],"in":[45,73,81,107,117],"animals":[46],"dosed":[47],"with":[48],"PFOA.":[49],"a":[53,74,83],"Benchmark":[54],"Dose":[55],"(BMD)":[56],"methodology":[57],"non-cancer":[59],"assessment":[61],"recommended":[62],"National":[65],"Academy":[66],"Sciences":[68],"as":[69],"preferred":[71],"approach":[72],"situation":[75],"analogous":[76],"to":[77],"PFOA,":[80],"which":[82,97],"without":[85],"harmful":[86],"effect":[87],"has":[88],"not":[89],"been":[90],"identified":[91],"lowdose":[93],"endpoints,":[94],"and":[95],"are":[100],"defined":[101],"on":[102],"basis":[104],"concentrations":[106],"blood":[108],"(2).":[109],"This":[110],"was":[112],"3M":[116],"its":[118],"recently":[119],"published":[120],"evaluation":[121],"risks":[125],"from":[126],"PFOA":[127],"exposures":[128],"(3).":[129]},"counts_by_year":[{"year":2014,"cited_by_count":2}],"updated_date":"2025-11-06T04:12:42.849631","created_date":"2016-06-24T00:00:00"}