{"id":"https://openalex.org/W2187501599","doi":null,"title":"Effect of Ubiquinone and Resveratrol on Experimentally Induced","display_name":"Effect of Ubiquinone and Resveratrol on Experimentally Induced","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W2187501599","mag":"2187501599"},"language":"en","primary_location":{"id":"mag:2187501599","doi":null,"is_oa":false,"landing_page_url":"https://omicsonline.com/open-access/effect-of-ubiquinone-and-resveratrol-on-experimentally-induced-parkinsonism.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033458349","display_name":"ParkinsonismM Kabel","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"ParkinsonismM Kabel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5065633068","display_name":"Sanad S El Kholy","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sanad S El Kholy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"1","issue":"3","first_page":"1","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9330999851226807,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9330999851226807,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13012","display_name":"Coenzyme Q10 studies and effects","score":0.061400000005960464,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13991","display_name":"Nuclear Receptors and Signaling","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":0.9959999918937683},{"id":"https://openalex.org/keywords/coenzyme-q10","display_name":"coenzyme Q10","score":0.9010000228881836},{"id":"https://openalex.org/keywords/resveratrol","display_name":"resveratrol","score":0.9779999852180481},{"id":"https://openalex.org/keywords/l-dopa","display_name":"L-DOPA","score":0.906000018119812},{"id":"https://openalex.org/keywords/mptp-induced-parkinsonism","display_name":"MPTP-induced parkinsonism","score":0.9890000224113464},{"id":"https://openalex.org/keywords/dopaminergic-neurons","display_name":"dopaminergic neurons","score":0.7009999752044678},{"id":"https://openalex.org/keywords/substantia-nigra","display_name":"substantia nigra","score":0.8659999966621399},{"id":"https://openalex.org/keywords/mitochondrial-dysfunction","display_name":"mitochondrial dysfunction","score":0.7929999828338623},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9649999737739563},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.9980000257492065},{"id":"https://openalex.org/keywords/striatal-dopamine","display_name":"striatal dopamine","score":0.7440000176429749},{"id":"https://openalex.org/keywords/glutathione-reductase","display_name":"glutathione reductase","score":0.8130000233650208},{"id":"https://openalex.org/keywords/malondialdehyde","display_name":"malondialdehyde","score":0.8019999861717224},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.9539999961853027},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.8880000114440918},{"id":"https://openalex.org/keywords/catalepsy","display_name":"catalepsy","score":0.8009999990463257},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.7200000286102295}],"concepts":[{"id":"https://openalex.org/C2778674702","wikidata":"https://www.wikidata.org/wiki/Q239816","display_name":"MPTP","level":4,"score":0.9276797771453857},{"id":"https://openalex.org/C2780938664","wikidata":"https://www.wikidata.org/wiki/Q753278","display_name":"Substantia nigra","level":4,"score":0.6867835521697998},{"id":"https://openalex.org/C2776816829","wikidata":"https://www.wikidata.org/wiki/Q407329","display_name":"Resveratrol","level":2,"score":0.6720417141914368},{"id":"https://openalex.org/C2778401633","wikidata":"https://www.wikidata.org/wiki/Q418661","display_name":"Malondialdehyde","level":3,"score":0.6473977565765381},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5634612441062927},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.5393677949905396},{"id":"https://openalex.org/C538909803","wikidata":"https://www.wikidata.org/wiki/Q116907","display_name":"Glutathione","level":3,"score":0.5366001129150391},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5199724435806274},{"id":"https://openalex.org/C137183658","wikidata":"https://www.wikidata.org/wiki/Q461076","display_name":"Dopaminergic","level":3,"score":0.49410274624824524},{"id":"https://openalex.org/C519581460","wikidata":"https://www.wikidata.org/wiki/Q207843","display_name":"Nitric oxide","level":2,"score":0.4844384491443634},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.4550004303455353},{"id":"https://openalex.org/C2776525014","wikidata":"https://www.wikidata.org/wiki/Q1531991","display_name":"Parkinsonism","level":3,"score":0.41003215312957764},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4018929600715637},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4016619324684143},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3634452223777771},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23306599259376526},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0943509042263031},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"mag:2187501599","doi":null,"is_oa":false,"landing_page_url":"https://omicsonline.com/open-access/effect-of-ubiquinone-and-resveratrol-on-experimentally-induced-parkinsonism.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"mag:2249688925","doi":null,"is_oa":false,"landing_page_url":"https://www.longdom.org/open-access/effect-of-ubiquinone-and-resveratrol-on-experimentally-induced-parkinsonism.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Journal of Research and Development","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9907000064849854,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W62603772","https://openalex.org/W1516068437","https://openalex.org/W1573392996","https://openalex.org/W1775749144","https://openalex.org/W1964477960","https://openalex.org/W1965621563","https://openalex.org/W1970979752","https://openalex.org/W1973894442","https://openalex.org/W1975619206","https://openalex.org/W1980131618","https://openalex.org/W1986118996","https://openalex.org/W1988091123","https://openalex.org/W1993735050","https://openalex.org/W2005395349","https://openalex.org/W2010414623","https://openalex.org/W2011222672","https://openalex.org/W2011963023","https://openalex.org/W2026166234","https://openalex.org/W2034908515","https://openalex.org/W2035492000","https://openalex.org/W2038205497","https://openalex.org/W2045984937","https://openalex.org/W2046632451","https://openalex.org/W2046857998","https://openalex.org/W2049509711","https://openalex.org/W2053054955","https://openalex.org/W2053180614","https://openalex.org/W2055930420","https://openalex.org/W2057394844","https://openalex.org/W2062001650","https://openalex.org/W2062781235","https://openalex.org/W2066762007","https://openalex.org/W2068223162","https://openalex.org/W2074475472","https://openalex.org/W2081026933","https://openalex.org/W2102323773","https://openalex.org/W2102440831","https://openalex.org/W2103258031","https://openalex.org/W2144592798","https://openalex.org/W2146887970","https://openalex.org/W2148071155","https://openalex.org/W2151317627","https://openalex.org/W2158211941","https://openalex.org/W2160188792","https://openalex.org/W2164666524","https://openalex.org/W2166926510","https://openalex.org/W2170667061","https://openalex.org/W2394508062","https://openalex.org/W2496090432"],"related_works":["https://openalex.org/W2249688925","https://openalex.org/W2932888163","https://openalex.org/W3127111450","https://openalex.org/W4386095609","https://openalex.org/W2045984937","https://openalex.org/W1981776904","https://openalex.org/W4309476570","https://openalex.org/W2519007348","https://openalex.org/W2912631745","https://openalex.org/W2392356594"],"abstract_inverted_index":{"Parkinson's":[0],"disease":[1],"is":[2,34,45,58],"one":[3],"of":[4,16,80,88,91,221],"the":[5,17,21,40,86,89,175,202,207,219],"motor":[6],"system":[7],"diseases":[8,75],"caused":[9],"by":[10],"factors":[11],"that":[12,51,63,209],"interfere":[13],"with":[14,98,186,198],"survival":[15],"dopaminergic":[18],"neurons":[19],"in":[20,39,47,96,105,174,189,201,239],"substantia":[22],"nigra.":[23],"Its":[24],"mechanisms":[25],"include":[26],"mitochondrial":[27,42,149,153,182],"dysfunction,":[28],"oxidative":[29],"stress":[30],"and":[31,44,76,94,157,166,181,195,223,227],"neuroinflammation.":[32],"Ubiquinone":[33],"a":[35,59,230],"fat-soluble":[36],"vitamin":[37],"found":[38],"inner":[41],"membrane":[43],"involved":[46],"electron":[48],"transport":[49],"chain":[50],"supplies":[52],"energy":[53],"to":[54,67,84,214],"vital":[55],"organs.":[56],"Resveratrol":[57],"natural":[60],"polyphenolic":[61],"compound":[62],"has":[64],"been":[65],"shown":[66],"offer":[68],"protective":[69],"effects":[70],"against":[71],"many":[72],"cardiovascular,":[73],"neurodegenerative":[74],"cancer.":[77],"The":[78,162],"aim":[79],"this":[81],"work":[82],"was":[83],"study":[85],"effect":[87,232],"combination":[90,163,220],"L-dopa,":[92],"ubiquinone":[93,127,168,224],"resveratrol":[95,133,170,228],"comparison":[97],"L-dopa":[99,121,125,131,165,211,222,226,234],"alone":[100,212,235],"on":[101,236],"1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine":[102],"(MPTP)-induced":[103],"parkinsonism":[104],"mice.":[106,240],"50":[107],"albino":[108],"mice":[109],"were":[110,160],"divided":[111],"into":[112],"5":[113],"equal":[114],"groups:":[115],"Control":[116],"untreated":[117],"group,":[118,120,124,130],"MPTP":[119,123,129,135],"+":[122,126,128,132,134],"group.":[136,216],"Striatal":[137],"dopamine,":[138,178],"tumor":[139],"necrosis":[140],"factor":[141],"alpha":[142],"(TNF-\u03b1),":[143],"glutathione":[144,179],"reductase,":[145],"malondialdehyde,":[146],"nitric":[147,193],"oxide,":[148],"adenosine":[150],"triphosphate":[151],"(ATP),":[152],"complex":[154,183],"I":[155,184],"activity":[156,185],"catalepsy":[158,203],"score":[159,204],"measured.":[161],"between":[164],"either":[167],"or":[169,225],"induced":[171],"significant":[172,187,199],"increase":[173],"striatal":[176,190],"ATP,":[177],"reductase":[180],"decrease":[188],"TNF-\u03b1":[191],"level,":[192],"oxide":[194],"malondialdehyde":[196],"level":[197],"improvement":[200],"better":[205,231],"than":[206,233],"group":[208],"received":[210],"compared":[213],"MPTP-treated":[215],"In":[217],"conclusion,":[218],"had":[229],"MPTP-induced":[237],"Parkinsonism":[238]},"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}