{"id":"https://openalex.org/W2187345485","doi":null,"title":"Natural therapies for ocular disorders, part one: diseases of the retina.","display_name":"Natural therapies for ocular disorders, part one: diseases of the retina.","publication_year":1999,"publication_date":"1999-10-01","ids":{"openalex":"https://openalex.org/W2187345485","mag":"2187345485","pmid":"https://pubmed.ncbi.nlm.nih.gov/10559549"},"language":"en","primary_location":{"id":"pmid:10559549","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10559549","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alternative medicine review : a journal of clinical therapeutic","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055293786","display_name":"Kathi Head","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"K A Head","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5055293786"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3001,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.53225654,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"4","issue":"5","first_page":"342","last_page":"59"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.9580000042915344,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.9580000042915344,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.0357000008225441,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/natural-medicine","display_name":"natural medicine","score":0.7139999866485596},{"id":"https://openalex.org/keywords/eye-diseases","display_name":"eye diseases","score":0.6690000295639038},{"id":"https://openalex.org/keywords/retinal-disease","display_name":"retinal disease","score":0.9409999847412109},{"id":"https://openalex.org/keywords/macular-degeneration","display_name":"macular degeneration","score":0.9789999723434448},{"id":"https://openalex.org/keywords/diabetic-retinopathy","display_name":"diabetic retinopathy","score":0.9990000128746033},{"id":"https://openalex.org/keywords/retinopathy-of-prematurity","display_name":"retinopathy of prematurity","score":0.9490000009536743},{"id":"https://openalex.org/keywords/retinitis-pigmentosa","display_name":"retinitis pigmentosa","score":0.9850000143051147},{"id":"https://openalex.org/keywords/vitamin-e","display_name":"vitamin E","score":0.6190000176429749},{"id":"https://openalex.org/keywords/vitamin-c","display_name":"vitamin C","score":0.8019999861717224},{"id":"https://openalex.org/keywords/carotenoids","display_name":"carotenoids","score":0.9860000014305115},{"id":"https://openalex.org/keywords/zinc","display_name":"zinc","score":0.7229999899864197},{"id":"https://openalex.org/keywords/selenium","display_name":"selenium","score":1.0},{"id":"https://openalex.org/keywords/antioxidants","display_name":"antioxidants","score":0.718999981880188},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.8679999709129333},{"id":"https://openalex.org/keywords/taurine","display_name":"taurine","score":0.9010000228881836},{"id":"https://openalex.org/keywords/vitamin-a-supplementation","display_name":"vitamin A supplementation","score":0.875},{"id":"https://openalex.org/keywords/dietary-intervention","display_name":"dietary intervention","score":0.41600000858306885}],"concepts":[{"id":"https://openalex.org/C2781114197","wikidata":"https://www.wikidata.org/wiki/Q847057","display_name":"Retinitis pigmentosa","level":3,"score":0.9035089015960693},{"id":"https://openalex.org/C2776403814","wikidata":"https://www.wikidata.org/wiki/Q27429789","display_name":"Macular degeneration","level":2,"score":0.6512587070465088},{"id":"https://openalex.org/C2779829184","wikidata":"https://www.wikidata.org/wiki/Q631361","display_name":"Diabetic retinopathy","level":3,"score":0.6230541467666626},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6197614669799805},{"id":"https://openalex.org/C2778313320","wikidata":"https://www.wikidata.org/wiki/Q550455","display_name":"Retinopathy","level":3,"score":0.5008373260498047},{"id":"https://openalex.org/C2779701627","wikidata":"https://www.wikidata.org/wiki/Q207051","display_name":"Taurine","level":3,"score":0.4609127640724182},{"id":"https://openalex.org/C2778129702","wikidata":"https://www.wikidata.org/wiki/Q2655893","display_name":"Vitamin A deficiency","level":4,"score":0.43529683351516724},{"id":"https://openalex.org/C2776940978","wikidata":"https://www.wikidata.org/wiki/Q34956","display_name":"Vitamin","level":2,"score":0.40587088465690613},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.40332239866256714},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.3981824517250061},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27738121151924133},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2522750496864319},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.21578696370124817},{"id":"https://openalex.org/C2779573558","wikidata":"https://www.wikidata.org/wiki/Q424976","display_name":"Retinol","level":3,"score":0.1932642161846161},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.14781039953231812},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1224689781665802},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000596","descriptor_name":"Amino Acids","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008517","descriptor_name":"Phytotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008903","descriptor_name":"Minerals","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D012164","descriptor_name":"Retinal Diseases","qualifier_ui":"Q000178","qualifier_name":"diet therapy","is_major_topic":false},{"descriptor_ui":"D012164","descriptor_name":"Retinal Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D012164","descriptor_name":"Retinal Diseases","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D014815","descriptor_name":"Vitamins","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:10559549","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10559549","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alternative medicine review : a journal of clinical therapeutic","raw_type":"Journal Article"},{"id":"mag:2187345485","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10559549","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0},{"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2","score":0.40450000762939453}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":91,"referenced_works":["https://openalex.org/W16176175","https://openalex.org/W28972838","https://openalex.org/W44893264","https://openalex.org/W45173793","https://openalex.org/W58303909","https://openalex.org/W73677737","https://openalex.org/W138633476","https://openalex.org/W155945970","https://openalex.org/W156851963","https://openalex.org/W182376669","https://openalex.org/W208033357","https://openalex.org/W1214309681","https://openalex.org/W1481288115","https://openalex.org/W1512972301","https://openalex.org/W1568669194","https://openalex.org/W1595216892","https://openalex.org/W1904985075","https://openalex.org/W1913824527","https://openalex.org/W1968097361","https://openalex.org/W1968328053","https://openalex.org/W1971090773","https://openalex.org/W1974834290","https://openalex.org/W1978693840","https://openalex.org/W1981897333","https://openalex.org/W1983227673","https://openalex.org/W1983478334","https://openalex.org/W1984490683","https://openalex.org/W1984892876","https://openalex.org/W1985174092","https://openalex.org/W1988041601","https://openalex.org/W1989335652","https://openalex.org/W1993746533","https://openalex.org/W1993979684","https://openalex.org/W1994752964","https://openalex.org/W1995926057","https://openalex.org/W2000334153","https://openalex.org/W2000663727","https://openalex.org/W2005335651","https://openalex.org/W2007111898","https://openalex.org/W2011481332","https://openalex.org/W2015734619","https://openalex.org/W2016200686","https://openalex.org/W2016982574","https://openalex.org/W2017071825","https://openalex.org/W2032849378","https://openalex.org/W2036317458","https://openalex.org/W2036409475","https://openalex.org/W2045604827","https://openalex.org/W2054872235","https://openalex.org/W2056643569","https://openalex.org/W2057572931","https://openalex.org/W2058846383","https://openalex.org/W2061439834","https://openalex.org/W2067762870","https://openalex.org/W2068222189","https://openalex.org/W2069157247","https://openalex.org/W2069425627","https://openalex.org/W2070536196","https://openalex.org/W2071315700","https://openalex.org/W2076485085","https://openalex.org/W2076605543","https://openalex.org/W2078471699","https://openalex.org/W2080678410","https://openalex.org/W2081824794","https://openalex.org/W2084274226","https://openalex.org/W2089878313","https://openalex.org/W2102446763","https://openalex.org/W2117127611","https://openalex.org/W2119442484","https://openalex.org/W2123460349","https://openalex.org/W2124115547","https://openalex.org/W2147440920","https://openalex.org/W2151384013","https://openalex.org/W2155003672","https://openalex.org/W2161727220","https://openalex.org/W2181480652","https://openalex.org/W2277961239","https://openalex.org/W2313592832","https://openalex.org/W2337454357","https://openalex.org/W2401739309","https://openalex.org/W2403485929","https://openalex.org/W2408961477","https://openalex.org/W2409137064","https://openalex.org/W2410021823","https://openalex.org/W2410691056","https://openalex.org/W2414503391","https://openalex.org/W2417064761","https://openalex.org/W2419802058","https://openalex.org/W2434323026","https://openalex.org/W2521067036","https://openalex.org/W4236696010"],"related_works":["https://openalex.org/W4398140875","https://openalex.org/W1794384384","https://openalex.org/W2127838013","https://openalex.org/W4307267206","https://openalex.org/W1563989015","https://openalex.org/W170043687","https://openalex.org/W2923507203","https://openalex.org/W2010499532","https://openalex.org/W77458768","https://openalex.org/W7151778246"],"abstract_inverted_index":{"Diseases":[0],"of":[1,8,28,30,39,51,67,109,139,145,149,161,167,200,207,222],"the":[2,5,11,24,40,49,62,137,143,150,173],"retina":[3],"are":[4,106],"leading":[6],"causes":[7],"blindness":[9],"throughout":[10],"world.":[12],"Evidence":[13],"points":[14,47],"to":[15,48,88,188,195,212],"potential":[16,50],"benefit":[17,224],"from":[18,225],"nutritional":[19],"and":[20,26,42,55,59,64,82,111,117,129,219],"botanical":[21],"interventions":[22],"for":[23,142],"prevention":[25,63,144],"treatment":[27,66],"several":[29],"these":[31],"conditions,":[32],"including":[33],"macular":[34,68],"degeneration,":[35],"diabetic":[36,93],"retinopathy,":[37],"retinopathy":[38,94,119],"newborn,":[41],"retinitis":[43,183,217],"pigmentosa.":[44],"Epidemiological":[45],"evidence":[46],"antioxidant":[52,132],"vitamins":[53],"E":[54,141,163],"C,":[56],"carotenoids,":[57],"zinc,":[58],"selenium":[60],"in":[61,78,85,159,177,191,216],"possible":[65],"degeneration.":[69],"In":[70],"addition,":[71],"dietary":[72],"components":[73],"such":[74],"as":[75],"red":[76],"wine-high":[77],"important":[79,131,202],"flavonoids-and":[80],"fruits":[81],"vegetables":[83],"high":[84],"carotenoids":[86],"appear":[87,187,194],"offer":[89],"some":[90],"protection.":[91],"While":[92,180],"can":[95],"best":[96],"be":[97,189],"prevented":[98],"by":[99,120],"maintaining":[100],"good":[101],"blood":[102],"sugar":[103],"control,":[104],"there":[105],"a":[107,214,220],"number":[108],"nutrients":[110],"botanicals":[112],"which":[113],"may":[114],"help":[115],"prevent":[116],"treat":[118],"inhibiting":[121],"protein":[122],"glycosylation,":[123],"stabilizing":[124],"collagen,":[125],"decreasing":[126],"capillary":[127],"permeability,":[128],"providing":[130],"effects.":[133],"Extensive":[134],"research":[135],"on":[136],"use":[138],"vitamin":[140,162,208],"retrolental":[146],"fibroplasia":[147],"(retinopathy":[148],"newborn),":[151],"despite":[152],"yielding":[153],"promising":[154],"results,":[155],"has":[156],"not":[157,186],"resulted":[158],"incorporation":[160],"into":[164],"conventional":[165],"standards":[166],"care":[168],"protocols.":[169],"Retinitis":[170],"pigmentosa":[171,184],"resembles":[172],"retinal":[174],"damage":[175],"seen":[176],"taurine-deficient":[178],"cats.":[179],"patients":[181,223],"with":[182],"do":[185],"deficient":[190],"taurine,":[192],"they":[193],"have":[196],"faulty":[197],"cellular":[198],"uptake":[199],"this":[201],"amino":[203],"acid.":[204],"Disturbed":[205],"utilization":[206],"A":[209],"also":[210],"appears":[211],"play":[213],"part":[215],"pigmentosa,":[218],"subgroup":[221],"supplementation.":[226]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}