{"id":"https://openalex.org/W2187304137","doi":null,"title":"Frequency and Predisposing Factors of Hepatocellular Carcinoma in a Hepatology Outpatient Unit","display_name":"Frequency and Predisposing Factors of Hepatocellular Carcinoma in a Hepatology Outpatient Unit","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2187304137","mag":"2187304137"},"language":"en","primary_location":{"id":"mag:2187304137","doi":null,"is_oa":false,"landing_page_url":"https://www.hsj.gr/abstract/frequency-and-predisposing-factors-of-hepatocellularrncarcinoma-in-a-hepatology-outpatient-unit-3802.html","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030142698","display_name":"Nikolaos V. Fotos","orcid":"https://orcid.org/0000-0001-8917-4012","observed_orcids":["https://orcid.org/0000-0001-8917-4012"]},"institutions":[{"id":"https://openalex.org/I200777214","display_name":"National and Kapodistrian University of Athens","ror":"https://ror.org/04gnjpq42","country_code":"GR","type":"education","lineage":["https://openalex.org/I200777214"]}],"countries":["GR"],"is_corresponding":false,"raw_author_name":"Fotos V Nikolaos","raw_affiliation_strings":["national & kapodistrian university of athens"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"national & kapodistrian university of athens","institution_ids":["https://openalex.org/I200777214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061074754","display_name":"Ioannis S Elefsiniotis","orcid":"https://orcid.org/0000-0002-8118-7190","observed_orcids":["https://orcid.org/0000-0002-8118-7190"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Elefsiniotis Ioannis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103623236","display_name":"Giakoumidakis Konstantinos","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Giakoumidakis Konstantinos","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059326720","display_name":"Evangelos Argyropoulos","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Evangelos Argyropoulos","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055843118","display_name":"Patris Vasileios","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Patris Vasileios","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5041349013","display_name":"Hero Brokalaki","orcid":"https://orcid.org/0000-0002-8597-081X","observed_orcids":["https://orcid.org/0000-0002-8597-081X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Brokalaki Hero","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1697,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.53158099,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"9","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.9746000170707703,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.9746000170707703,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10340","display_name":"Hepatitis B Virus Studies","score":0.019200000911951065,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10151","display_name":"Hepatitis C virus research","score":0.002199999988079071,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"hepatocellular carcinoma","score":0.9919999837875366},{"id":"https://openalex.org/keywords/chronic-viral-hepatitis","display_name":"chronic viral hepatitis","score":0.9639999866485596},{"id":"https://openalex.org/keywords/chronic-hepatitis-b","display_name":"chronic hepatitis B","score":0.9679999947547913},{"id":"https://openalex.org/keywords/chronic-hepatitis-c","display_name":"chronic hepatitis C","score":1.0},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.9139999747276306},{"id":"https://openalex.org/keywords/liver-cirrhosis","display_name":"liver cirrhosis","score":0.8989999890327454},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.9950000047683716},{"id":"https://openalex.org/keywords/age","display_name":"age","score":0.48899999260902405},{"id":"https://openalex.org/keywords/duration-of-infection","display_name":"infection duration","score":0.6759999990463257}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8423731923103333},{"id":"https://openalex.org/C41260117","wikidata":"https://www.wikidata.org/wiki/Q668064","display_name":"Hepatology","level":2,"score":0.8262374401092529},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7950230240821838},{"id":"https://openalex.org/C3019393901","wikidata":"https://www.wikidata.org/wiki/Q232932","display_name":"Open access publishing","level":2,"score":0.7725753784179688},{"id":"https://openalex.org/C2778019345","wikidata":"https://www.wikidata.org/wiki/Q1148337","display_name":"Hepatocellular carcinoma","level":2,"score":0.767387866973877},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.5623039603233337},{"id":"https://openalex.org/C3020110884","wikidata":"https://www.wikidata.org/wiki/Q695416","display_name":"Outpatient clinic","level":2,"score":0.4625382423400879},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.12304842472076416},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2187304137","doi":null,"is_oa":false,"landing_page_url":"https://www.hsj.gr/abstract/frequency-and-predisposing-factors-of-hepatocellularrncarcinoma-in-a-hepatology-outpatient-unit-3802.html","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W162512385","https://openalex.org/W1920952588","https://openalex.org/W1966804887","https://openalex.org/W1988051941","https://openalex.org/W2002004237","https://openalex.org/W2008039498","https://openalex.org/W2013054466","https://openalex.org/W2023725755","https://openalex.org/W2029318640","https://openalex.org/W2054789893","https://openalex.org/W2092740203","https://openalex.org/W2093542694","https://openalex.org/W2094608386","https://openalex.org/W2096314243","https://openalex.org/W2097494822","https://openalex.org/W2100798947","https://openalex.org/W2116448477","https://openalex.org/W2118901299","https://openalex.org/W2142137274","https://openalex.org/W2153883677","https://openalex.org/W2154841493","https://openalex.org/W2155893993","https://openalex.org/W2171354548"],"related_works":["https://openalex.org/W4399747106","https://openalex.org/W4400012550","https://openalex.org/W7138856841","https://openalex.org/W2893475285","https://openalex.org/W2560286568","https://openalex.org/W2311183637","https://openalex.org/W3201705971","https://openalex.org/W2518979558","https://openalex.org/W2503106639","https://openalex.org/W2062038385"],"abstract_inverted_index":{"Background:":[0],"Patientswithchronicviralhepatitisareathighriskofdeveloping\ufffd":[1],"hepatocellularcarcinoma\ufffd(HCC).\ufffdVariouspredisposingfactorshavebeendescribed\ufffd":[2],"fortheoccurrenceofHCCinthesepatients.\ufffd":[3],"Theaimofthepresentstudywasto\ufffd":[4],"identifytheseriskfactors.":[5],"Method":[6],"and":[7],"Material:\ufffdAretrospectivedescriptiveepidemiologicalstudy,\ufffdof\ufffd549\ufffd":[8],"patientswithchronicviralhepatitiswasconducted.\ufffdPatientswereexaminedfrom\ufffd":[9],"January":[10],"1":[11],"st":[12,14],"\ufffd2007\ufffdtoSeptember\ufffd31":[13],"2013\ufffdattheHepatologyoutpatientunitofa\ufffd":[15],"GeneralHospitalofAthens-Greece.\ufffdDemographic,\ufffdclinicalcharacteristicsofpatients\ufffd":[16],"andlaboratorytestresultsweregatheredfromtheregistryoftheoutpatientunit.\ufffd":[17],"StatisticalanalysiswasperformedwiththePASW18\ufffdsoftware,\ufffd":[18],"usingPearson'schi-":[19],"squaretest.\ufffdPvaluesoflessthan\ufffd0.05\ufffdwereconsideredsignificant.":[20],"Results:":[21],"Filesof\ufffd549\ufffdexaminedpatientsintheoutpatientunitwerereviewedand\ufffd":[22],"253\ufffd(46.1%)\ufffdwerediagnosedwithchronichepatitisB\ufffd(CHB)\ufffdand\ufffd296\ufffd(53.9%)\ufffdwith\ufffd":[23],"chronichepatitisC\ufffd(CHC).\ufffdThemajorityofpatients\ufffd(57.2%)\ufffdweremenandless\ufffd":[24],"than\ufffd65\ufffdyearsold\ufffd(87.4%).\ufffdThefrequencyofHCCwas\ufffd4.4%\ufffd(24\ufffdpatients).\ufffdFifteen\ufffd":[25],"patientswerediagnosedwithCHBand\ufffd9\ufffdwithCHC\ufffd(P=0.039).\ufffdThefactorsfound\ufffd":[26],"tobeassociatedwiththedevelopmentofHCCinourstudywereage\ufffd\u2265\ufffd65\ufffdyears\ufffd":[27],"(P<0.001),\ufffddiabetesmellitus\ufffd(P=0.003),\ufffdchronicity\ufffd(\u2265\ufffd10\ufffdyears)\ufffdofviralinfection\ufffd":[28],"(P=0.007)\ufffdandlivercirrhosis\ufffd(P<0.001).":[29],"Conclusions:":[30],"TheprevalenceofHCCwassignificantlyhigherin":[31],"patientswithCHB\ufffd":[32],"comparedwithCHCpatients.\ufffd":[33],"Age\ufffd\u2265\ufffd65\ufffdyears,\ufffddiabetesmellitus,\ufffdchronicityofviral\ufffd":[34],"infectionandlivercirrhosiswerethemainpredisposingfactorsfortheoccurrence\ufffd":[35],"ofHCC.\ufffdTheearlydiagnosisofdiabetesandtheearlytreatmentofviralhepatitis\ufffd":[36],"couldcontributetothepreventionofHCC.\ufffd\ufffd":[37]},"counts_by_year":[{"year":2017,"cited_by_count":1}],"updated_date":"2026-10-12T09:40:04.860316","created_date":"2016-06-24T00:00:00"}