{"id":"https://openalex.org/W2187269679","doi":null,"title":"HPTLC DETERMINATION OF FREE PAROXETINE IN HUMAN SERUM","display_name":"HPTLC DETERMINATION OF FREE PAROXETINE IN HUMAN SERUM","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2187269679","mag":"2187269679"},"language":"en","primary_location":{"id":"mag:2187269679","doi":null,"is_oa":false,"landing_page_url":"https://www.ijpbs.net/cms/php/upload/3590_pdf.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764788474","display_name":"International Journal of Pharma and Bio Sciences","issn_l":"0975-6299","issn":["0975-6299"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4322697007","host_organization_name":"Ubitech Solutions","host_organization_lineage":["https://openalex.org/P4322697007"],"host_organization_lineage_names":["Ubitech Solutions"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Pharma and Bio Sciences","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"P. B. Pushpalatha","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P. B. Pushpalatha","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102548631","display_name":"Rajendra Kumar Sarin","orcid":"https://orcid.org/0000-0001-5126-1866","observed_orcids":["https://orcid.org/0000-0001-5126-1866"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rajendra Kumar Sarin","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-5126-1866","affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Mohd Hanafi Idris","orcid":"https://orcid.org/0000-0003-3003-4108","observed_orcids":["https://orcid.org/0000-0003-3003-4108"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mohd Hanafi Idris","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3003-4108","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028888740","display_name":"Mesineni Anand Rao","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mesineni Anand Rao","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112459321","display_name":"Tulsidas Ramachandra Rao Baggi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tulsidas Ramachandra Rao Baggi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5086204982","display_name":"M. Satish Varma","orcid":"https://orcid.org/0009-0006-0912-8432","observed_orcids":["https://orcid.org/0009-0006-0912-8432"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Satish Varma","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10800","display_name":"Forensic Toxicology and Drug Analysis","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10800","display_name":"Forensic Toxicology and Drug Analysis","score":0.9804999828338623,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":0.018799999728798866,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10908","display_name":"Analytical Chemistry and Chromatography","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/paroxetine","display_name":"paroxetine","score":0.9909999966621399},{"id":"https://openalex.org/keywords/free-drug-quantification","display_name":"free drug quantification","score":0.8360000252723694},{"id":"https://openalex.org/keywords/human-serum","display_name":"human serum","score":0.9800000190734863},{"id":"https://openalex.org/keywords/hptlc","display_name":"HPTLC","score":0.7739999890327454},{"id":"https://openalex.org/keywords/forensic-toxicology","display_name":"forensic toxicology","score":0.7599999904632568},{"id":"https://openalex.org/keywords/drug-detection","display_name":"drug detection","score":0.40400001406669617},{"id":"https://openalex.org/keywords/liquid-liquid-extraction","display_name":"liquid-liquid extraction","score":0.8600000143051147},{"id":"https://openalex.org/keywords/densitometric-analysis","display_name":"densitometric analysis","score":0.6710000038146973},{"id":"https://openalex.org/keywords/method-validation","display_name":"method validation","score":0.5}],"concepts":[{"id":"https://openalex.org/C119128265","wikidata":"https://www.wikidata.org/wiki/Q900165","display_name":"Detection limit","level":2,"score":0.7890962362289429},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.7561960220336914},{"id":"https://openalex.org/C23531484","wikidata":"https://www.wikidata.org/wiki/Q3196863","display_name":"Calibration curve","level":3,"score":0.7169873118400574},{"id":"https://openalex.org/C2779532046","wikidata":"https://www.wikidata.org/wiki/Q308976","display_name":"Silica gel","level":2,"score":0.5629610419273376},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5521921515464783},{"id":"https://openalex.org/C95986675","wikidata":"https://www.wikidata.org/wiki/Q185168","display_name":"Quantitative analysis (chemistry)","level":2,"score":0.41056588292121887},{"id":"https://openalex.org/C113196181","wikidata":"https://www.wikidata.org/wiki/Q485223","display_name":"Analytical Chemistry (journal)","level":2,"score":0.32378318905830383}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2187269679","doi":null,"is_oa":false,"landing_page_url":"https://www.ijpbs.net/cms/php/upload/3590_pdf.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764788474","display_name":"International Journal of Pharma and Bio Sciences","issn_l":"0975-6299","issn":["0975-6299"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4322697007","host_organization_name":"Ubitech Solutions","host_organization_lineage":["https://openalex.org/P4322697007"],"host_organization_lineage_names":["Ubitech Solutions"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Pharma and Bio Sciences","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8199999928474426,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":34,"referenced_works":["https://openalex.org/W1605185674","https://openalex.org/W1972642955","https://openalex.org/W1973808585","https://openalex.org/W1984359144","https://openalex.org/W1990404021","https://openalex.org/W1996825251","https://openalex.org/W2001191499","https://openalex.org/W2019914348","https://openalex.org/W2021366235","https://openalex.org/W2026973648","https://openalex.org/W2028678429","https://openalex.org/W2031500874","https://openalex.org/W2032495422","https://openalex.org/W2033763423","https://openalex.org/W2037911192","https://openalex.org/W2042648503","https://openalex.org/W2049489184","https://openalex.org/W2058776829","https://openalex.org/W2060032237","https://openalex.org/W2066610947","https://openalex.org/W2067903360","https://openalex.org/W2074050752","https://openalex.org/W2074735840","https://openalex.org/W2086678059","https://openalex.org/W2089234222","https://openalex.org/W2091003844","https://openalex.org/W2091185023","https://openalex.org/W2127273541","https://openalex.org/W2130471373","https://openalex.org/W2131075465","https://openalex.org/W2142008729","https://openalex.org/W2151135774","https://openalex.org/W2162253908","https://openalex.org/W2486780633"],"related_works":["https://openalex.org/W4235535156","https://openalex.org/W2019914348","https://openalex.org/W2408955787","https://openalex.org/W1990720855","https://openalex.org/W2083229713","https://openalex.org/W1975841224","https://openalex.org/W2151135774","https://openalex.org/W2391216779","https://openalex.org/W2067044568","https://openalex.org/W2043462218"],"abstract_inverted_index":{"A":[0],"rapid,":[1],"sensitive":[2],"and":[3,12,52,98,119,127,145,166],"specific":[4],"high-performance":[5],"thin-layer":[6],"chromatographic":[7],"(HPTLC)":[8],"method":[9,38,158],"was":[10,29,73,137],"developed":[11],"validated":[13],"for":[14,61],"quantitative":[15],"determination":[16],"of":[17,26,64,83,91,100,102,131,147,152,156],"free":[18,27,65,132,161],"Paroxetine":[19],"(PAX)":[20],"in":[21,79,171],"human":[22,135],"serum.":[23],"Densitometric":[24],"analysis":[25],"PAX":[28,66,133,162],"carried":[30],"at":[31],"293nm":[32],"after":[33],"simple":[34],"liquid-liquid":[35],"extraction.":[36],"The":[37,70,154],"uses":[39],"HPTLC":[40],"aluminium":[41],"plates":[42],"pre-coated":[43],"with":[44,88,163],"silica":[45],"gel":[46],"G":[47],"60F254":[48],"as":[49,58],"stationary":[50],"phase":[51,60],"acetone:":[53],"carbon":[54],"tetrachloride:":[55],"triethylamine":[56],"(5:5:0.3,v/v/v)":[57],"mobile":[59],"the":[62,80,148],"separation":[63],"from":[67,112,134,142],"serum":[68,113,136],"constituents.":[69],"calibration":[71],"curve":[72],"linear":[74],"(r":[75],"2":[76],"=":[77],"0.996)":[78],"tested":[81],"range":[82],"95-240":[84],"ng":[85,95,105],"spot":[86,96,106],"-1":[87,97,107],"a":[89],"limit":[90,99],"detection":[92],"(LOD)":[93],"30":[94],"quantification":[101],"(LOQ)":[103],"95":[104],".":[108],"Free":[109],"drug":[110],"recovery":[111],"averaged":[114],"94.4%":[115],"to":[116,159],"99.28%.":[117],"Intra-":[118],"inter-day":[120],"precision":[121],"(%":[122],"RSD)":[123],"values":[124],"were":[125],"<1.83%":[126],"<5.66%,":[128],"respectively.":[129],"Analysis":[130],"successfully":[138],"performed":[139],"without":[140],"interference":[141],"endogenous":[143],"materials":[144],"some":[146],"other":[149],"common":[150],"drugs":[151],"abuse.":[153],"ability":[155],"this":[157],"quantify":[160],"precision,":[164],"accuracy":[165],"sensitivity":[167],"makes":[168],"it":[169],"useful":[170],"forensic":[172],"examination.":[173]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2016-06-24T00:00:00"}