{"id":"https://openalex.org/W2187201608","doi":null,"title":"Diethylstilbestrol-Treated Adult Rats with Altered Epididymal Sperm Numbers and Sperm Motility Parameters, but Without Alterations in Sperm Production","display_name":"Diethylstilbestrol-Treated Adult Rats with Altered Epididymal Sperm Numbers and Sperm Motility Parameters, but Without Alterations in Sperm Production","publication_year":2001,"publication_date":"2001-01-01","ids":{"openalex":"https://openalex.org/W2187201608","mag":"2187201608"},"language":"en","primary_location":{"id":"mag:2187201608","doi":null,"is_oa":false,"landing_page_url":"https://www.bioone.org/doi/pdf/10.1095/biolreprod64.3.927","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017699305","display_name":"Sperm Morphology","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sperm Morphology","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064574473","display_name":"Hari Om Goyal","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hari Om Goyal","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101461695","display_name":"Mahmoud M Mansour","orcid":"https://orcid.org/0000-0003-0268-3573","observed_orcids":["https://orcid.org/0000-0003-0268-3573"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mahmoud Mansour","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0268-3573","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5079657878","display_name":"A. Kamaleldin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. Kamaleldin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.22072988,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10686","display_name":"Effects and risks of endocrine disrupting chemicals","score":0.8134999871253967,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10686","display_name":"Effects and risks of endocrine disrupting chemicals","score":0.8134999871253967,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.16599999368190765,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diethylstilbestrol","display_name":"diethylstilbestrol","score":1.0},{"id":"https://openalex.org/keywords/estrogenic-effects","display_name":"estrogenic effects","score":0.703000009059906},{"id":"https://openalex.org/keywords/male-reproductive-toxicity","display_name":"male reproductive toxicity","score":0.7760000228881836},{"id":"https://openalex.org/keywords/epididymal-sperm-count","display_name":"epididymal sperm count","score":0.8889999985694885},{"id":"https://openalex.org/keywords/sperm-motility","display_name":"sperm motility","score":0.9980000257492065},{"id":"https://openalex.org/keywords/epididymis","display_name":"epididymis","score":0.722000002861023},{"id":"https://openalex.org/keywords/seminal-vesicle","display_name":"seminal vesicle","score":0.9959999918937683},{"id":"https://openalex.org/keywords/spermatogenesis","display_name":"spermatogenesis","score":0.921999990940094},{"id":"https://openalex.org/keywords/testosterone","display_name":"testosterone","score":0.6549999713897705},{"id":"https://openalex.org/keywords/luteinizing-hormone","display_name":"luteinizing hormone","score":0.8880000114440918},{"id":"https://openalex.org/keywords/fertility","display_name":"fertility","score":0.7990000247955322},{"id":"https://openalex.org/keywords/dose-response-relationship","display_name":"dose-response relationship","score":0.8130000233650208},{"id":"https://openalex.org/keywords/endocrine-disruptors","display_name":"endocrine disruptors","score":0.6779999732971191}],"concepts":[{"id":"https://openalex.org/C2781087480","wikidata":"https://www.wikidata.org/wiki/Q17145","display_name":"Sperm","level":2,"score":0.8451375961303711},{"id":"https://openalex.org/C2781254305","wikidata":"https://www.wikidata.org/wiki/Q1973610","display_name":"Epididymis","level":3,"score":0.7863840460777283},{"id":"https://openalex.org/C123765429","wikidata":"https://www.wikidata.org/wiki/Q36961","display_name":"Spermatogenesis","level":2,"score":0.7208498120307922},{"id":"https://openalex.org/C2777632594","wikidata":"https://www.wikidata.org/wiki/Q27116486","display_name":"Sperm motility","level":3,"score":0.6901815533638},{"id":"https://openalex.org/C2778206080","wikidata":"https://www.wikidata.org/wiki/Q856775","display_name":"Corn oil","level":2,"score":0.6413354873657227},{"id":"https://openalex.org/C2781397067","wikidata":"https://www.wikidata.org/wiki/Q423989","display_name":"Diethylstilbestrol","level":3,"score":0.5890077948570251},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5593915581703186},{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.5379036664962769},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5307742357254028},{"id":"https://openalex.org/C2781171107","wikidata":"https://www.wikidata.org/wiki/Q217259","display_name":"Seminal vesicle","level":4,"score":0.51531982421875},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5081026554107666},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.5026097297668457},{"id":"https://openalex.org/C58207958","wikidata":"https://www.wikidata.org/wiki/Q33596","display_name":"Motility","level":2,"score":0.4718587100505829},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.21576601266860962},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.15021950006484985},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.14663320779800415},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2187201608","doi":null,"is_oa":false,"landing_page_url":"https://www.bioone.org/doi/pdf/10.1095/biolreprod64.3.927","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W1513211408","https://openalex.org/W1544169104","https://openalex.org/W1676501327","https://openalex.org/W1963785171","https://openalex.org/W1967167117","https://openalex.org/W1985747461","https://openalex.org/W1988611170","https://openalex.org/W1988719974","https://openalex.org/W1991130847","https://openalex.org/W1997049000","https://openalex.org/W2005813248","https://openalex.org/W2013977341","https://openalex.org/W2016167081","https://openalex.org/W2016323993","https://openalex.org/W2019590136","https://openalex.org/W2028768910","https://openalex.org/W2035725571","https://openalex.org/W2039472232","https://openalex.org/W2041455522","https://openalex.org/W2045366965","https://openalex.org/W2058636110","https://openalex.org/W2070282026","https://openalex.org/W2070907292","https://openalex.org/W2073883348","https://openalex.org/W2077320485","https://openalex.org/W2080058556","https://openalex.org/W2087902564","https://openalex.org/W2100898329","https://openalex.org/W2101984211","https://openalex.org/W2127288137","https://openalex.org/W2128242453","https://openalex.org/W2140870683","https://openalex.org/W2146355385","https://openalex.org/W2149350777","https://openalex.org/W2149870169","https://openalex.org/W2152454741","https://openalex.org/W2153596741","https://openalex.org/W2155274896","https://openalex.org/W2162143779","https://openalex.org/W2170716128","https://openalex.org/W2298699312"],"related_works":["https://openalex.org/W2159834699","https://openalex.org/W2109060290","https://openalex.org/W2023729384","https://openalex.org/W2941803300","https://openalex.org/W1965451195","https://openalex.org/W7097983931","https://openalex.org/W7095138627","https://openalex.org/W1987335784","https://openalex.org/W2026254092","https://openalex.org/W2021651734"],"abstract_inverted_index":{"In":[0,234],"this":[1],"study,":[2,238],"we":[3],"characterized":[4],"estrogenic":[5],"effects":[6,87],"of":[7,47,50,58,111,116,121,129,134,147,174,193,245],"diethylstilbestrol":[8],"(DES)":[9],"on":[10,34],"reproductive":[11],"parameters":[12,177],"in":[13,90,105,131,141,156,167,178,206,216,224],"male":[14],"rats":[15,41],"to":[16,191,201,211],"identify":[17],"a":[18,56,212,235,243],"minimal":[19],"dose":[20,96],"level":[21,198,205,215,231],"that":[22],"alters":[23],"epididymal":[24],"and":[25,94,98,108,114,124,137,170,186,210],"sperm":[26,35,130,142,161,171],"functions":[27],"but":[28,229],"has":[29],"little":[30],"or":[31,38,69,226],"no":[32,151],"effect":[33],"production":[36],"and/":[37],"spermatogenesis.":[39],"Adult":[40],"(five":[42],"animals/group)":[43],"received":[44,82,240],"s.c.":[45],"injections":[46],"0.2":[48],"ml":[49],"corn":[51,83],"oil":[52,84],"containing":[53],"DES":[54,86,241],"at":[55,242],"rate":[57,244],"1.0":[59],"mg,":[60,62,64,66,68],"200":[61],"40":[63],"8":[65],"1.6":[67],"320":[70],"ng":[71],"rat":[72],"21":[73,75],"day":[74],"for":[76],"12":[77],"days.":[78],"The":[79],"control":[80],"group":[81,93,181,188,219],"only.":[85],"were":[88,154,189],"similar":[89],"the":[91,112,117,122,135,145,148,175,179,207,217],"8-mg":[92],"higher":[95],"groups":[97,209],"included":[99],"significant":[100,152],"(P":[101],"#":[102],"0.05)":[103],"reductions":[104],"1)":[106],"absolute":[107],"relative":[109,157],"weights":[110],"head":[113],"body":[115],"epididymis":[118],"(EP),":[119],"tail":[120,146],"EP,":[123,136],"seminal":[125,183],"vesicle,":[126],"2)":[127],"numbers":[128],"both":[132],"regions":[133],"3)":[138],"motility":[139],"characteristics":[140],"collected":[143],"from":[144],"EP.":[149],"Conversely,":[150],"changes":[153],"observed":[155],"testis":[158],"weight,":[159],"daily":[160],"production,":[162],"spermatogenesis,":[163],"seminiferous":[164],"epithelial":[165],"height":[166],"stage":[168],"VII,":[169],"morphology.":[172],"All":[173],"above":[176],"1.6-mg":[180,218],"(except":[182],"vesicle":[184],"weight)":[185],"320-ng":[187,227],"comparable":[190],"those":[192],"controls.":[194],"Plasma":[195],"testosterone":[196],"(T)":[197],"was":[199,232],"reduced":[200],"an":[202],"almost":[203],"undetectable":[204],"$8-mg":[208],"very":[213],"low":[214],"(0.35":[220],"vs.":[221],"2.36":[222],"ng/ml":[223],"controls":[225],"group),":[228],"LH":[230],"unaltered.":[233],"parallel":[236],"fertility":[237],"males":[239],"40,":[246]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2016-06-24T00:00:00"}