{"id":"https://openalex.org/W2186976560","doi":null,"title":"Some Biochemical and Haematological Studies on the Methanolic Extract of Anthocleista Grandiflora Stem Bark","display_name":"Some Biochemical and Haematological Studies on the Methanolic Extract of Anthocleista Grandiflora Stem Bark","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W2186976560","mag":"2186976560"},"language":"en","primary_location":{"id":"mag:2186976560","doi":null,"is_oa":false,"landing_page_url":"http://www.ijastnet.com/journals/Vol_2_No_5_May_2012/6.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061956809","display_name":"Odeghe Othuke","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Odeghe Othuke","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5061956809"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9344,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.76921509,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9818999767303467,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9818999767303467,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12685","display_name":"Phytochemical compounds biological activities","score":0.010900000110268593,"subfield":{"id":"https://openalex.org/subfields/3002","display_name":"Drug Discovery"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/stem-bark-extract","display_name":"stem bark extract","score":0.8820000290870667},{"id":"https://openalex.org/keywords/methanol-extract","display_name":"methanol extract","score":0.8289999961853027},{"id":"https://openalex.org/keywords/plasmodium-berghei","display_name":"Plasmodium berghei","score":0.9139999747276306},{"id":"https://openalex.org/keywords/malaria","display_name":"malaria","score":0.7429999709129333},{"id":"https://openalex.org/keywords/chloroquine","display_name":"chloroquine","score":0.9169999957084656},{"id":"https://openalex.org/keywords/antimalarial-activity","display_name":"antimalarial activity","score":0.7820000052452087},{"id":"https://openalex.org/keywords/hematological-parameters","display_name":"hematological parameters","score":0.8679999709129333},{"id":"https://openalex.org/keywords/liver-enzymes","display_name":"liver enzymes","score":0.6230000257492065},{"id":"https://openalex.org/keywords/aspartate-aminotransferase","display_name":"aspartate aminotransferase","score":0.9309999942779541},{"id":"https://openalex.org/keywords/alanine-aminotransferase","display_name":"alanine aminotransferase","score":0.996999979019165},{"id":"https://openalex.org/keywords/alkaline-phosphatase","display_name":"alkaline phosphatase","score":0.9890000224113464},{"id":"https://openalex.org/keywords/urea","display_name":"urea","score":0.8569999933242798},{"id":"https://openalex.org/keywords/mice","display_name":"mice","score":0.35499998927116394}],"concepts":[{"id":"https://openalex.org/C160160445","wikidata":"https://www.wikidata.org/wiki/Q24769688","display_name":"Alkaline phosphatase","level":3,"score":0.6770727634429932},{"id":"https://openalex.org/C2777425658","wikidata":"https://www.wikidata.org/wiki/Q422438","display_name":"Chloroquine","level":3,"score":0.5760138034820557},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.5636993050575256},{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.5223796963691711},{"id":"https://openalex.org/C2777397205","wikidata":"https://www.wikidata.org/wiki/Q275792","display_name":"Saline","level":2,"score":0.5056633949279785},{"id":"https://openalex.org/C2992872382","wikidata":"https://www.wikidata.org/wiki/Q305481","display_name":"Alanine aminotransferase","level":2,"score":0.5007786750793457},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4757665991783142},{"id":"https://openalex.org/C2777237215","wikidata":"https://www.wikidata.org/wiki/Q65021","display_name":"Plasmodium berghei","level":3,"score":0.47084566950798035},{"id":"https://openalex.org/C3018023364","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Significant difference","level":2,"score":0.4370039999485016},{"id":"https://openalex.org/C2780365088","wikidata":"https://www.wikidata.org/wiki/Q48318","display_name":"Urea","level":2,"score":0.43026003241539},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3656703531742096},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3642290532588959},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.29817214608192444},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.25915732979774475},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.21085262298583984},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1385599672794342}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2186976560","doi":null,"is_oa":false,"landing_page_url":"http://www.ijastnet.com/journals/Vol_2_No_5_May_2012/6.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W13647380","https://openalex.org/W158489181","https://openalex.org/W1481014086","https://openalex.org/W1499233278","https://openalex.org/W1535207151","https://openalex.org/W1545004908","https://openalex.org/W1902076426","https://openalex.org/W1960332590","https://openalex.org/W1979336714","https://openalex.org/W1986200639","https://openalex.org/W1986459557","https://openalex.org/W1995354641","https://openalex.org/W2001672474","https://openalex.org/W2003471941","https://openalex.org/W2006514190","https://openalex.org/W2013340411","https://openalex.org/W2014862126","https://openalex.org/W2029918421","https://openalex.org/W2058946584","https://openalex.org/W2080183548","https://openalex.org/W2092425839","https://openalex.org/W2107188298","https://openalex.org/W2125299541","https://openalex.org/W2132507895","https://openalex.org/W2138999678","https://openalex.org/W2144252964","https://openalex.org/W2169304723","https://openalex.org/W2183488156","https://openalex.org/W2256248620","https://openalex.org/W2490450809","https://openalex.org/W2492480966","https://openalex.org/W2618895222","https://openalex.org/W2798310077"],"related_works":["https://openalex.org/W4415938734","https://openalex.org/W2338244561","https://openalex.org/W3169068700","https://openalex.org/W1998045748","https://openalex.org/W7098554395","https://openalex.org/W3037014071","https://openalex.org/W7199636541","https://openalex.org/W7008581876","https://openalex.org/W4416568823","https://openalex.org/W7132895395"],"abstract_inverted_index":{"This":[0],"research":[1],"was":[2],"designed":[3],"to":[4,121],"access":[5],"the":[6,21,25,31,127,145],"interaction":[7,29],"of":[8,23,27,33,38,132],"Anthocleista":[9],"grandiflora":[10],"plant":[11],"and":[12,46,55,60,68,77,86,92,96,115,142],"chloroquine":[13,99],"in":[14,30,111,144],"mice":[15,40],"induced":[16],"with":[17,20,62,70,79,88,98,126],"Plasmodium":[18],"berghei":[19],"aim":[22],"ascertaining":[24],"significance":[26],"such":[28],"treatment":[32],"malaria":[34,146],"infection.":[35],"A":[36],"total":[37],"89":[39],"were":[41,47,148],"used":[42],"for":[43],"this":[44],"study":[45],"divided":[48],"into":[49],"six":[50],"groups.":[51],"Group":[52,57,65],"1":[53],"uninfected":[54],"untreated,":[56],"2":[58],"infected":[59,67,76,85,95,103],"treated":[61,69,78,87,97,105],"normal":[63],"saline,":[64],"3":[66,120],"300mg/kg":[71],"b.wt":[72,81,90],"extract,":[73,82],"group":[74,83,93],"4":[75],"500mg/kg":[80],"5":[84],"700mg/kg":[89],"extract":[91,104],"6":[94],"(5mg/kg":[100],"b.wt).":[101],"The":[102,129],"animals":[106],"had":[107],"significant":[108],"(P<0.05)":[109],"difference":[110],"PCV,":[112],"Hb,":[113],"WBC":[114],"platelet":[116],"count":[117],"from":[118],"day":[119,122],"14":[123],"when":[124],"compared":[125],"control.":[128],"elevated":[130],"levels":[131],"aspartate":[133],"aminotransferase":[134,137],"(AST),":[135],"alanine":[136],"(ALT),":[138],"alkaline":[139],"phosphatase":[140],"(ALP)":[141],"urea":[143],"rats":[147],"significantly":[149],"(p<0.05)":[150],"decreased.":[151]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":3}],"updated_date":"2025-11-06T04:12:42.849631","created_date":"2016-06-24T00:00:00"}