{"id":"https://openalex.org/W2186945703","doi":null,"title":"Development of Different Polymer Matrix Systems for Galantamine Hydrobromide Sustained Release","display_name":"Development of Different Polymer Matrix Systems for Galantamine Hydrobromide Sustained Release","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2186945703","mag":"2186945703"},"language":"en","primary_location":{"id":"mag:2186945703","doi":null,"is_oa":false,"landing_page_url":"http://globalresearchonline.net/journalcontents/v30-1/21.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026757371","display_name":"Angel Aleksiev","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Angel Aleksiev","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050394583","display_name":"Bistra Kostova","orcid":"https://orcid.org/0000-0003-0296-2150","observed_orcids":["https://orcid.org/0000-0003-0296-2150"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bistra Kostova","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0296-2150","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5007179311","display_name":"Dimitar Rachev","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dimitar Rachev","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.9550999999046326,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.9550999999046326,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.029400000348687172,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/galantamine-hydrobromide","display_name":"galantamine hydrobromide","score":1.0},{"id":"https://openalex.org/keywords/sustained-release","display_name":"sustained drug release","score":0.8939999938011169},{"id":"https://openalex.org/keywords/hydrophilic-polymers","display_name":"hydrophilic polymers","score":0.7360000014305115},{"id":"https://openalex.org/keywords/hydrophobic-polymers","display_name":"hydrophobic polymers","score":0.9120000004768372},{"id":"https://openalex.org/keywords/methocel","display_name":"Methocel","score":0.7149999737739563},{"id":"https://openalex.org/keywords/swelling-rate","display_name":"swelling rate","score":0.6150000095367432},{"id":"https://openalex.org/keywords/erosion-rate","display_name":"erosion rate","score":0.9210000038146973},{"id":"https://openalex.org/keywords/in-vitro-drug-release","display_name":"in vitro drug release","score":0.875},{"id":"https://openalex.org/keywords/release-kinetics","display_name":"release kinetics","score":0.8420000076293945},{"id":"https://openalex.org/keywords/fickian-diffusion","display_name":"Fickian diffusion","score":0.9309999942779541},{"id":"https://openalex.org/keywords/non-fickian-diffusion","display_name":"non-Fickian diffusion","score":0.8289999961853027}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5943238735198975},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.5857839584350586},{"id":"https://openalex.org/C69357855","wikidata":"https://www.wikidata.org/wiki/Q163214","display_name":"Diffusion","level":2,"score":0.5477355122566223},{"id":"https://openalex.org/C2778540859","wikidata":"https://www.wikidata.org/wiki/Q152234","display_name":"Swelling","level":2,"score":0.5273153185844421},{"id":"https://openalex.org/C106487976","wikidata":"https://www.wikidata.org/wiki/Q685816","display_name":"Matrix (chemical analysis)","level":2,"score":0.5127614140510559},{"id":"https://openalex.org/C2779176119","wikidata":"https://www.wikidata.org/wiki/Q20974920","display_name":"Hydrobromide","level":2,"score":0.45738476514816284},{"id":"https://openalex.org/C148898269","wikidata":"https://www.wikidata.org/wiki/Q1108792","display_name":"Kinetics","level":2,"score":0.4202921390533447},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.3251917064189911},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.3202117383480072},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.23220860958099365},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.1820824146270752},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.12245070934295654},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.11728796362876892},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2186945703","doi":null,"is_oa":false,"landing_page_url":"http://globalresearchonline.net/journalcontents/v30-1/21.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.7246000170707703,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1545800183","https://openalex.org/W1977072597","https://openalex.org/W2016149437","https://openalex.org/W2026403832","https://openalex.org/W2029890144","https://openalex.org/W2043264586","https://openalex.org/W2074561945","https://openalex.org/W2080316505","https://openalex.org/W2086130473","https://openalex.org/W2088756537","https://openalex.org/W2108042514","https://openalex.org/W2122320288","https://openalex.org/W2175242143","https://openalex.org/W2187048991","https://openalex.org/W2468385695","https://openalex.org/W2470021514","https://openalex.org/W2488522105"],"related_works":["https://openalex.org/W2188165820","https://openalex.org/W2076387183","https://openalex.org/W2787061458","https://openalex.org/W3093772567","https://openalex.org/W2900829248","https://openalex.org/W2189249990","https://openalex.org/W2362254616","https://openalex.org/W2554142812","https://openalex.org/W6986141871","https://openalex.org/W4210689424"],"abstract_inverted_index":{"This":[0],"paper":[1],"outlines":[2],"the":[3,19,57,71,86,89,96],"development":[4],"of":[5,26,56,78,88],"controlled":[6],"release":[7,74,98],"matrix":[8],"systems":[9],"containing":[10],"galantamine":[11,79],"hydrobromide.":[12,80],"The":[13,44],"model":[14],"compositions":[15],"were":[16,60,65],"developed":[17],"by":[18],"direct":[20],"compression":[21],"technique,":[22],"using":[23],"a":[24],"variety":[25],"hydrophilic":[27],"and":[28,38,46,76],"hydrophobic":[29],"polymer":[30,90],"carriers:":[31],"Methocel\u00ae":[32,34],"K100LV,":[33],"K4M,":[35],"Kollidon\u00ae":[36,39],"VA64":[37],"SR":[40],"at":[41],"different":[42],"concentrations.":[43],"swelling":[45],"erosion":[47],"rate,":[48],"as":[49,51],"well":[50],"in":[52,67,72,95],"vitro":[53,73],"drugrelease":[54],"characteristics":[55],"studied":[58],"matrices":[59],"investigated.":[61],"Various":[62],"mathematical":[63],"models":[64],"used":[66],"order":[68],"to":[69,93,103],"evaluate":[70],"kinetics":[75],"mechanism":[77,99],"It":[81],"was":[82],"found":[83],"out":[84],"that":[85],"increase":[87],"quantity":[91],"leads":[92],"change":[94],"drug":[97],"from":[100],"Fickian":[101],"diffusion":[102],"Anomalous":[104],"(non-Fickian)":[105],"diffusion.":[106]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}