{"id":"https://openalex.org/W2186942563","doi":null,"title":"Retinol Binding Protien-4 Levels in Early Diabetic Nephropathy in Egyptian Patients with Type 2 Diabetes","display_name":"Retinol Binding Protien-4 Levels in Early Diabetic Nephropathy in Egyptian Patients with Type 2 Diabetes","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W2186942563","mag":"2186942563"},"language":"en","primary_location":{"id":"mag:2186942563","doi":null,"is_oa":false,"landing_page_url":"http://www.idosi.org/gjbb/gjbb10(1)15/6.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026328995","display_name":"Ibrahim W. Hasani","orcid":"https://orcid.org/0000-0002-7333-5851","observed_orcids":["https://orcid.org/0000-0002-7333-5851"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Ibrahim W. Hasani","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-7333-5851","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5026328995"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.11216107,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":95},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.6601999998092651,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.6601999998092651,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.33149999380111694,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10170","display_name":"Retinal Diseases and Treatments","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/retinol-binding-protein-4","display_name":"retinol-binding protein 4","score":0.9850000143051147},{"id":"https://openalex.org/keywords/diabetic-nephropathy","display_name":"diabetic nephropathy","score":0.9089999794960022},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.949999988079071},{"id":"https://openalex.org/keywords/microalbuminuria","display_name":"microalbuminuria","score":0.984000027179718},{"id":"https://openalex.org/keywords/adipokines","display_name":"adipokines","score":0.9380000233650208},{"id":"https://openalex.org/keywords/serum-biomarkers","display_name":"serum biomarkers","score":0.7200000286102295},{"id":"https://openalex.org/keywords/glycemic-control","display_name":"glycemic control","score":0.6759999990463257},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.6840000152587891}],"concepts":[{"id":"https://openalex.org/C2776465410","wikidata":"https://www.wikidata.org/wiki/Q14911599","display_name":"Retinol binding protein 4","level":5,"score":0.8663082718849182},{"id":"https://openalex.org/C2781203188","wikidata":"https://www.wikidata.org/wiki/Q1676817","display_name":"Microalbuminuria","level":3,"score":0.8390688896179199},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.83226478099823},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7528624534606934},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.7318775653839111},{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.6586992740631104},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.5675871968269348},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.5620410442352295},{"id":"https://openalex.org/C2779922275","wikidata":"https://www.wikidata.org/wiki/Q1129105","display_name":"Diabetic nephropathy","level":3,"score":0.5370010733604431},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.49228063225746155},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.47111940383911133},{"id":"https://openalex.org/C2781184683","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Nephropathy","level":3,"score":0.43520915508270264},{"id":"https://openalex.org/C194832188","wikidata":"https://www.wikidata.org/wiki/Q2638593","display_name":"Adipokine","level":4,"score":0.4312061667442322}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2186942563","doi":null,"is_oa":false,"landing_page_url":"http://www.idosi.org/gjbb/gjbb10(1)15/6.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1490939051","https://openalex.org/W1991398238","https://openalex.org/W1991944268","https://openalex.org/W1992259695","https://openalex.org/W2040365189","https://openalex.org/W2060140841","https://openalex.org/W2087460127","https://openalex.org/W2138947863","https://openalex.org/W2141124822","https://openalex.org/W2151516056","https://openalex.org/W2161835278","https://openalex.org/W2169055011","https://openalex.org/W2182150538","https://openalex.org/W2468012934"],"related_works":["https://openalex.org/W2066141991","https://openalex.org/W2076583954","https://openalex.org/W2355748920","https://openalex.org/W3083897754","https://openalex.org/W1992259695","https://openalex.org/W4312820967","https://openalex.org/W2130540377","https://openalex.org/W2086351020","https://openalex.org/W2147316125","https://openalex.org/W2391647256"],"abstract_inverted_index":{"3":[0],"Abstract:":[1],"Plasma":[2],"retinol-binding":[3],"protein":[4],"4":[5],"(RBP4)":[6],"is":[7,30,66],"a":[8,80,84],"new":[9],"adipokine":[10],"linked":[11],"to":[12,37,121,152,262,270,273,278],"obesity-induced":[13],"insulin":[14],"resistance":[15],"and":[16,46,93,109,117,129,205,207,220,231,248,269],"type":[17,75,89,309],"2":[18,64,76,90,192,308,310],"diabetes.":[19],"The":[20,103,234],"impact":[21],"of":[22,44,72,87,190,285,295],"diabetic":[23,77,91,311],"nephropathy":[24],"on":[25],"serum":[26,42,70,145,156,188,235,257,286,304],"RBP4":[27,45,73,128,146,191,219,236,258,287,305],"levels,":[28],"however,":[29],"not":[31],"well":[32,173],"known.":[33],"This":[34],"study":[35,59,301],"aimed":[36],"investigate":[38],"the":[39,57,61,100,122,249,293,299],"relationships":[40],"between":[41,218],"levels":[43,158,237,259,284,306],"various":[47,274],"metabolic":[48],"parameters":[49,276],"in":[50,74,99,125,144,148,159,164,175,238,245,265,292,307],"Egyptian":[51],"patients":[52,92,112,166,178,240,247,312],"with":[53,68,168,180,196,210,267,281],"T":[54,185,296],"DM.":[55,297],"Additionally,":[56],"present":[58,101,300],"tested":[60],"hypothesis":[62],"that":[63,256,303],"microalbuminuria":[65,118],"associated":[67,280],"elevated":[69,264],"concentrations":[71,147],"subjects.":[78,251],"In":[79,184],"case":[81],"control":[82,153,170,182,250],"study,":[83],"total":[85],"number":[86],"60":[88],"20":[94],"healthy":[95],"subjects":[96,150,266],"were":[97,105,113,131,161,214,241,260],"enrolled":[98],"study.":[102],"participants":[104],"matched":[106],"by":[107,133,315],"age":[108],"sex.":[110],"Diabetic":[111],"classified":[114],"into":[115],"normoalbuminuria":[116],"subgroups":[119],"according":[120],"microalbumin":[123],"level":[124],"urine.":[126],"Serum":[127],"micoalbumin":[130],"measured":[132],"an":[134],"enzyme-linked":[135],"immunosorbent":[136],"assay":[137],"(ELISA).The":[138],"results":[139],"demonstrated":[140],"statistically":[141],"significant":[142,216],"elevation":[143],"T2DM":[149,165,177,268],"compared":[151,167,179],"subjects,":[154],"also":[155],"RBP-4":[157],"males":[160],"significantly":[162,242],"higher":[163,243],"male":[169],"group,":[171],"as":[172,174],"females":[176],"female":[181,211],"group.":[183],"DM":[186],"patients,":[187],"concentration":[189],"was":[193],"positively":[194],"correlated":[195,209],"age,":[197],"fasting":[198],"blood":[199,203],"sugar,":[200],"post":[201],"prandial":[202],"sugar":[204],"HbA1c":[206],"inversely":[208],"gender.":[212],"There":[213],"no":[215],"correlations":[217],"BMI,":[221],"GFR,":[222],"cholesterol,":[223],"triglyceride,":[224],"HDL,":[225],"LDL,":[226],"urea,":[227],"creatinine,":[228],"creatinine":[229],"clearance":[230],"uric":[232],"acid.":[233],"micromacroalbuminuric":[239],"than":[244],"normoalbuminuric":[246],"It":[252],"could":[253],"be":[254,263,271,279],"concluded":[255],"found":[261],"related":[272],"clinical":[275],"known":[277],"T2DM,":[282],"so":[283],"might":[288],"play":[289],"important":[290],"role":[291],"pathogenesis":[294],"Also,":[298],"suggests":[302],"are":[313],"affected":[314],"incipient":[316],"nephropathy.":[317]},"counts_by_year":[{"year":2022,"cited_by_count":2}],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}