{"id":"https://openalex.org/W2186844006","doi":null,"title":"Triple Antiplatelet Therapy in Acute Coronary Syndrome in 2014","display_name":"Triple Antiplatelet Therapy in Acute Coronary Syndrome in 2014","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W2186844006","mag":"2186844006"},"language":"en","primary_location":{"id":"mag:2186844006","doi":null,"is_oa":false,"landing_page_url":"http://www.csi.org.in/Cardio_pdf/SEC_1/Ch-18.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050767196","display_name":"Rajeev Lochan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Rajeev Lochan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5050767196"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11064","display_name":"Antiplatelet Therapy and Cardiovascular Diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11064","display_name":"Antiplatelet Therapy and Cardiovascular Diseases","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/triple-antiplatelet-therapy","display_name":"triple antiplatelet therapy","score":0.9950000047683716},{"id":"https://openalex.org/keywords/acute-coronary-syndrome","display_name":"acute coronary syndrome","score":0.9990000128746033},{"id":"https://openalex.org/keywords/percutaneous-coronary-intervention","display_name":"percutaneous coronary intervention","score":0.9879999756813049},{"id":"https://openalex.org/keywords/platelet-aggregation","display_name":"platelet aggregation","score":0.6499999761581421},{"id":"https://openalex.org/keywords/clopidogrel","display_name":"clopidogrel","score":0.7670000195503235},{"id":"https://openalex.org/keywords/ticlopidine","display_name":"ticlopidine","score":0.875},{"id":"https://openalex.org/keywords/aspirin","display_name":"aspirin","score":0.9750000238418579},{"id":"https://openalex.org/keywords/warfarin","display_name":"warfarin","score":0.9010000228881836},{"id":"https://openalex.org/keywords/vitamin-k-antagonists","display_name":"vitamin K antagonists","score":0.7360000014305115},{"id":"https://openalex.org/keywords/antiplatelet-drugs","display_name":"antiplatelet agents","score":0.6169999837875366},{"id":"https://openalex.org/keywords/bleeding-risk","display_name":"bleeding risk","score":0.6520000100135803},{"id":"https://openalex.org/keywords/stent-implantation","display_name":"stenting","score":0.6000000238418579},{"id":"https://openalex.org/keywords/coronary-thrombosis","display_name":"coronary thrombosis","score":0.6470000147819519}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9064896106719971},{"id":"https://openalex.org/C2777849778","wikidata":"https://www.wikidata.org/wiki/Q410237","display_name":"Clopidogrel","level":3,"score":0.6386094689369202},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6361259818077087},{"id":"https://openalex.org/C2777698277","wikidata":"https://www.wikidata.org/wiki/Q266018","display_name":"Acute coronary syndrome","level":3,"score":0.6098947525024414},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5781130194664001},{"id":"https://openalex.org/C2781362458","wikidata":"https://www.wikidata.org/wiki/Q1588755","display_name":"Thrombus","level":2,"score":0.5700669884681702},{"id":"https://openalex.org/C2780326628","wikidata":"https://www.wikidata.org/wiki/Q539795","display_name":"Angioplasty","level":2,"score":0.533564567565918},{"id":"https://openalex.org/C2780400711","wikidata":"https://www.wikidata.org/wiki/Q2008344","display_name":"Percutaneous coronary intervention","level":3,"score":0.5074467062950134},{"id":"https://openalex.org/C2777628954","wikidata":"https://www.wikidata.org/wiki/Q18216","display_name":"Aspirin","level":2,"score":0.4958668649196625},{"id":"https://openalex.org/C45393284","wikidata":"https://www.wikidata.org/wiki/Q191012","display_name":"Conventional PCI","level":3,"score":0.4341140687465668},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3230486214160919},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.23232784867286682}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2186844006","doi":null,"is_oa":false,"landing_page_url":"http://www.csi.org.in/Cardio_pdf/SEC_1/Ch-18.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":74,"referenced_works":["https://openalex.org/W9692900","https://openalex.org/W18470154","https://openalex.org/W42860337","https://openalex.org/W191387349","https://openalex.org/W207590421","https://openalex.org/W979638655","https://openalex.org/W1519150396","https://openalex.org/W1964913108","https://openalex.org/W1975843310","https://openalex.org/W1979363567","https://openalex.org/W1980104968","https://openalex.org/W1981102487","https://openalex.org/W1990988714","https://openalex.org/W1991549653","https://openalex.org/W2001688139","https://openalex.org/W2003506380","https://openalex.org/W2016234644","https://openalex.org/W2022311002","https://openalex.org/W2024531696","https://openalex.org/W2025238343","https://openalex.org/W2026202162","https://openalex.org/W2030747318","https://openalex.org/W2032335787","https://openalex.org/W2040251457","https://openalex.org/W2040335095","https://openalex.org/W2041936661","https://openalex.org/W2049913259","https://openalex.org/W2053379248","https://openalex.org/W2053481310","https://openalex.org/W2055474976","https://openalex.org/W2059136191","https://openalex.org/W2064739148","https://openalex.org/W2069049455","https://openalex.org/W2075868476","https://openalex.org/W2083900024","https://openalex.org/W2084210046","https://openalex.org/W2084632272","https://openalex.org/W2085260510","https://openalex.org/W2085652917","https://openalex.org/W2087305090","https://openalex.org/W2096069261","https://openalex.org/W2097646648","https://openalex.org/W2100089051","https://openalex.org/W2107547421","https://openalex.org/W2109450652","https://openalex.org/W2113089341","https://openalex.org/W2113513640","https://openalex.org/W2127090290","https://openalex.org/W2127489984","https://openalex.org/W2136351044","https://openalex.org/W2139834809","https://openalex.org/W2141610267","https://openalex.org/W2142848477","https://openalex.org/W2143582526","https://openalex.org/W2143777566","https://openalex.org/W2158389123","https://openalex.org/W2159258236","https://openalex.org/W2160395675","https://openalex.org/W2162886638","https://openalex.org/W2166950143","https://openalex.org/W2167166510","https://openalex.org/W2169387542","https://openalex.org/W2316166446","https://openalex.org/W2316376271","https://openalex.org/W2325460018","https://openalex.org/W2329622594","https://openalex.org/W2329837630","https://openalex.org/W2330351728","https://openalex.org/W2395313915","https://openalex.org/W2400296613","https://openalex.org/W2422601502","https://openalex.org/W2493925730","https://openalex.org/W3022148767","https://openalex.org/W3105096449"],"related_works":["https://openalex.org/W3094531551","https://openalex.org/W59652332","https://openalex.org/W289741063","https://openalex.org/W2154032239","https://openalex.org/W7100414107","https://openalex.org/W1968958117","https://openalex.org/W2085856226","https://openalex.org/W1569563801","https://openalex.org/W2533431678","https://openalex.org/W2078423968"],"abstract_inverted_index":{"INTRODUCTION":[0],"Percutaneous":[1],"coronary":[2,118,201],"intervention":[3],"(PCI)":[4],"is":[5,37,121,131],"performed":[6],"by":[7,15,80,85,123],"intracoronary":[8],"balloon":[9,140],"dilatation":[10],"of":[11,31,135,150,175],"atheromatous":[12],"plaque":[13,126],"narrowing":[14],"a":[16,167,193],"controlled":[17,84],"injury.":[18],"Endothelial":[19],"injury":[20,141],"stimulates":[21],"platelet":[22,88],"aggregation,":[23],"clumping":[24],"and":[25,53,75,90,105,112,156,185,192,203,207],"thrombus":[26,36,51,81,110],"formation":[27,52,82,111],"utilizing":[28],"various":[29],"factors":[30],"coagulation":[32],"cascade.":[33],"If":[34],"this":[35,96],"bulky":[38],"then":[39],"it":[40],"can":[41,142],"lead":[42],"to":[43,188],"vascular":[44,146],"obstruction.":[45],"Acetyl":[46],"salicylic":[47],"acid":[48],"(aspirin)":[49],"limits":[50],"was":[54,83,166],"used":[55,67],"in":[56,70,95,170,172,205],"PCI":[57,79,165],"or":[58,69],"angioplasty.1-7":[59],"Vitamin":[60],"K":[61],"antagonist":[62],"(VKA)":[63],"warfarin":[64],"has":[65,162,212],"been":[66,163,213],"alone":[68],"combination":[71,210],"with":[72,128],"aspirin.8-11":[73],"Acute":[74,117],"subacute":[76],"occlusion":[77,160],"after":[78,200],"counteracting":[86],"the":[87,92,109,124,145,158,181],"aggregation":[89],"agglutination,":[91],"first":[93],"step":[94],"process.":[97],"Later":[98],"stronger":[99],"adenosine":[100],"receptor":[101],"pathway":[102],"blockers":[103],"ticlopidine":[104],"clopidogrel":[106],"drastically":[107],"reduced":[108],"replaced":[113],"antithrombotic":[114,186],"agent":[115],"warfarin.12-15":[116],"syndrome":[119],"(ACS)":[120],"precipitated":[122],"vulnerable":[125],"rupture":[127],"hyperactive":[129],"platelets,":[130],"at":[132],"high":[133],"risk":[134],"thrombotic":[136],"occlusion.":[137,147],"Even":[138],"therapeutic":[139],"further":[143],"accelerate":[144],"In":[148],"spite":[149],"dual":[151],"antiplatelet":[152,184],"agents,":[153],"e.g.":[154],"aspirin":[155],"clopidogrel,":[157],"acute":[159,190],"post-PCI":[161],"unacceptable.":[164],"relative":[168],"contraindication":[169],"ACS":[171],"early":[173],"days":[174],"angioplasty":[176,202],"era.":[177],"Search":[178],"for":[179,208],"finding":[180],"newer":[182],"better":[183],"agents":[187],"limit":[189],"thrombosis":[191],"triple":[194],"therapy":[195],"without":[196],"aggravating":[197],"systemic":[198],"bleeding":[199],"stenting":[204],"ACSs":[206],"best":[209],"regimen":[211],"continued.":[214]},"counts_by_year":[],"updated_date":"2025-11-06T04:12:42.849631","created_date":"2016-06-24T00:00:00"}
