{"id":"https://openalex.org/W2186561283","doi":null,"title":"Diabetes and Cardiovascular Disease Intensive Glucose Lowering and Cardiovascular Disease Prevention in Diabetes Reconciling the Recent Clinical Trial Data","display_name":"Diabetes and Cardiovascular Disease Intensive Glucose Lowering and Cardiovascular Disease Prevention in Diabetes Reconciling the Recent Clinical Trial Data","publication_year":2016,"publication_date":"2016-09-12","ids":{"openalex":"https://openalex.org/W2186561283","mag":"2186561283"},"language":"en","primary_location":{"id":"pmh:oai:CiteSeerX.psu:10.1.1.873.3932","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.873.3932","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://circ.ahajournals.org/content/122/21/2201.full.pdf","raw_type":"text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110088558","display_name":"Theodore Mazzone","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Theodore Mazzone Md","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5110088558"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.00160531,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.9150000214576721,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.9150000214576721,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.06459999829530716,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":0.010200000368058681,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cardiovascular-disease-prevention","display_name":"cardiovascular disease prevention","score":0.9150000214576721},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.8669999837875366},{"id":"https://openalex.org/keywords/type-1-diabetes","display_name":"type 1 diabetes","score":0.9869999885559082},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.8320000171661377},{"id":"https://openalex.org/keywords/carotid-intima-media-thickness","display_name":"carotid intima-media thickness","score":0.9509999752044678},{"id":"https://openalex.org/keywords/coronary-artery-calcium","display_name":"coronary artery calcium","score":0.9959999918937683},{"id":"https://openalex.org/keywords/cardiovascular-risk-factors","display_name":"cardiovascular risk factors","score":0.7250000238418579},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.6209999918937683},{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.8610000014305115},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.7799999713897705},{"id":"https://openalex.org/keywords/blood-coagulation","display_name":"coagulation","score":0.8899999856948853}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8572914600372314},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.770351767539978},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6907143592834473},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.6578093767166138},{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.5937342047691345},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.583162784576416},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5703074932098389},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.540486216545105},{"id":"https://openalex.org/C2994533308","wikidata":"https://www.wikidata.org/wiki/Q5629407","display_name":"Coronary artery calcium","level":3,"score":0.47740212082862854},{"id":"https://openalex.org/C2909478654","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Atherosclerotic cardiovascular disease","level":3,"score":0.4610063433647156},{"id":"https://openalex.org/C2779339615","wikidata":"https://www.wikidata.org/wiki/Q2698596","display_name":"Intima-media thickness","level":3,"score":0.4208138883113861},{"id":"https://openalex.org/C2987047532","wikidata":"https://www.wikidata.org/wiki/Q214275","display_name":"Carotid arteries","level":2,"score":0.4111219644546509},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.17740607261657715}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:CiteSeerX.psu:10.1.1.873.3932","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.873.3932","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://circ.ahajournals.org/content/122/21/2201.full.pdf","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":76,"referenced_works":["https://openalex.org/W1502524639","https://openalex.org/W1526927233","https://openalex.org/W1594856996","https://openalex.org/W1752045965","https://openalex.org/W1782778410","https://openalex.org/W1967265218","https://openalex.org/W1967539655","https://openalex.org/W1969157512","https://openalex.org/W1972063989","https://openalex.org/W1977952802","https://openalex.org/W1983007636","https://openalex.org/W1983269691","https://openalex.org/W1988270660","https://openalex.org/W1994064869","https://openalex.org/W2023239847","https://openalex.org/W2031484324","https://openalex.org/W2034501137","https://openalex.org/W2035717904","https://openalex.org/W2037449342","https://openalex.org/W2042518766","https://openalex.org/W2048587558","https://openalex.org/W2050820265","https://openalex.org/W2053365438","https://openalex.org/W2056762166","https://openalex.org/W2063489619","https://openalex.org/W2064617441","https://openalex.org/W2070327180","https://openalex.org/W2075812158","https://openalex.org/W2076573528","https://openalex.org/W2091525545","https://openalex.org/W2097703150","https://openalex.org/W2099478560","https://openalex.org/W2100089051","https://openalex.org/W2100738935","https://openalex.org/W2100945845","https://openalex.org/W2101699044","https://openalex.org/W2102643074","https://openalex.org/W2106774879","https://openalex.org/W2107776862","https://openalex.org/W2110600904","https://openalex.org/W2113570813","https://openalex.org/W2115616588","https://openalex.org/W2116544253","https://openalex.org/W2118710233","https://openalex.org/W2120861740","https://openalex.org/W2125921569","https://openalex.org/W2126805583","https://openalex.org/W2127365004","https://openalex.org/W2129902595","https://openalex.org/W2138533265","https://openalex.org/W2138674605","https://openalex.org/W2139171405","https://openalex.org/W2141819264","https://openalex.org/W2143600334","https://openalex.org/W2144020184","https://openalex.org/W2144125787","https://openalex.org/W2145138855","https://openalex.org/W2147563150","https://openalex.org/W2148034645","https://openalex.org/W2148715056","https://openalex.org/W2152084424","https://openalex.org/W2154442601","https://openalex.org/W2158666727","https://openalex.org/W2159969745","https://openalex.org/W2165379936","https://openalex.org/W2166180770","https://openalex.org/W2167788046","https://openalex.org/W2168205528","https://openalex.org/W2170271198","https://openalex.org/W2170942247","https://openalex.org/W2171294019","https://openalex.org/W2172232070","https://openalex.org/W2172488527","https://openalex.org/W2188846692","https://openalex.org/W2337454357","https://openalex.org/W3001949083"],"related_works":["https://openalex.org/W2099342238","https://openalex.org/W7095919366","https://openalex.org/W7099212011","https://openalex.org/W1973110506","https://openalex.org/W3025320509","https://openalex.org/W82798829","https://openalex.org/W4365457168","https://openalex.org/W2186895859","https://openalex.org/W7100086060","https://openalex.org/W2039647866"],"abstract_inverted_index":{"Cardiovascular":[0],"disease":[1],"(CVD)":[2],"is":[3,27,97],"a":[4,28,112],"very":[5],"common,":[6,10],"if":[7],"notthe":[8],"most":[9],"cause":[11],"of":[12,89,114],"morbidity":[13],"and":[14,19,92,110,120,123,132],"mortality":[15],"in":[16,57,95,116,121],"developed":[17],"countries,":[18],"there":[20],"has":[21],"been":[22,65],"longstanding":[23],"recog-nition":[24],"that":[25,126],"diabetes":[26,42,62,96,105],"potent":[29],"risk":[30,94],"factor":[31],"for":[32],"CVD.1\u20133":[33],"Individuals":[34],"with":[35,61,102],"either":[36],"type":[37,40,103],"1":[38],"or":[39,80],"2":[41,104],"mellitus":[43,106],"manifest":[44,111],"CVD":[45,93],"rates":[46],"up":[47],"to":[48,50,67,129,133],"4":[49],"10":[51],"times":[52],"higher":[53],"than":[54],"those":[55],"observed":[56],"nondiabetic":[58],"subjects.":[59],"Subjects":[60],"also":[63],"have":[64,68,108],"shown":[66],"more":[69],"advanced":[70],"atherosclerosis,":[71],"as":[72],"measured":[73],"by":[74],"carotid":[75],"intima-media":[76],"thickness":[77],"(CIMT)":[78],"mea-sures":[79],"coronary":[81],"artery":[82],"calcium":[83],"(CAC)":[84],"scores.4\u20137":[85],"The":[86],"potential":[87],"pathophysiology":[88],"accelerated":[90],"atherosclero-sis":[91],"complex8":[98],"(Table":[99],"1).":[100],"Patients":[101],"commonly":[107],"hypertension":[109],"number":[113],"abnormalities":[115],"systemic":[117],"lipopro-tein":[118],"metabolism":[119],"inflammatory":[122],"coagulation":[124],"path-ways":[125],"are":[127],"predicted":[128],"be":[130],"proatherogenic":[131],"increase":[134]},"counts_by_year":[{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2025-10-27T00:00:00"}
