{"id":"https://openalex.org/W2186470745","doi":"https://doi.org/10.1515/znc-1987-0620","title":"Site-Directed Mutations of Two Histidine Residues in the D2 Protein Inactivate and Destabilize Photosystem II in the Cyanobacterium Synechocystis 6803","display_name":"Site-Directed Mutations of Two Histidine Residues in the D2 Protein Inactivate and Destabilize Photosystem II in the Cyanobacterium Synechocystis 6803","publication_year":1987,"publication_date":"1987-06-01","ids":{"openalex":"https://openalex.org/W2186470745","doi":"https://doi.org/10.1515/znc-1987-0620","mag":"2186470745"},"language":"en","primary_location":{"id":"doi:10.1515/znc-1987-0620","doi":"https://doi.org/10.1515/znc-1987-0620","is_oa":true,"landing_page_url":"https://doi.org/10.1515/znc-1987-0620","pdf_url":"https://www.degruyter.com/document/doi/10.1515/znc-1987-0620/pdf","source":{"id":"https://openalex.org/S67401564","display_name":"Zeitschrift f\u00fcr Naturforschung C","issn_l":"0341-0471","issn":["0341-0471","0939-5075","1865-7125"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift f\u00fcr Naturforschung C","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.degruyter.com/document/doi/10.1515/znc-1987-0620/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014328287","display_name":"Wim F. J. Vermaas","orcid":"https://orcid.org/0000-0003-3322-2737","observed_orcids":["https://orcid.org/0000-0003-3322-2737"]},"institutions":[{"id":"https://openalex.org/I1316910977","display_name":"DuPont (United States)","ror":"https://ror.org/03g3m1w62","country_code":"US","type":"company","lineage":["https://openalex.org/I1316910977"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wim F. J. Vermaas","raw_affiliation_strings":["E. I. du Pont de Nemours and Company. Central Research and Development Department. Building 402. Wilmington. DE 19898. USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"E. I. du Pont de Nemours and Company. Central Research and Development Department. Building 402. Wilmington. DE 19898. USA","institution_ids":["https://openalex.org/I1316910977"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109238934","display_name":"John Garnett Williams","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316910977","display_name":"DuPont (United States)","ror":"https://ror.org/03g3m1w62","country_code":"US","type":"company","lineage":["https://openalex.org/I1316910977"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John G. K. Williams","raw_affiliation_strings":["E. I. du Pont de Nemours and Company. Central Research and Development Department. Building 402. Wilmington. DE 19898. USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"E. I. du Pont de Nemours and Company. Central Research and Development Department. Building 402. Wilmington. DE 19898. USA","institution_ids":["https://openalex.org/I1316910977"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006641197","display_name":"Charles J. Arntzen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316910977","display_name":"DuPont (United States)","ror":"https://ror.org/03g3m1w62","country_code":"US","type":"company","lineage":["https://openalex.org/I1316910977"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles J. Arntzen","raw_affiliation_strings":["E. I. du Pont de Nemours and Company. Central Research and Development Department. Building 402. Wilmington. DE 19898. USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"E. I. du Pont de Nemours and Company. Central Research and Development Department. Building 402. Wilmington. DE 19898. USA","institution_ids":["https://openalex.org/I1316910977"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I1316910977"],"apc_list":{"value":2400,"currency":"EUR","value_usd":2712},"apc_paid":{"value":2400,"currency":"EUR","value_usd":2712},"fwci":1.7905,"has_fulltext":true,"cited_by_count":32,"citation_normalized_percentile":{"value":0.86010555,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"42","issue":"6","first_page":"762","last_page":"768"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10303","display_name":"Photosynthetic Processes and Mechanisms","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10303","display_name":"Photosynthetic Processes and Mechanisms","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11626","display_name":"Metalloenzymes and iron-sulfur proteins","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2105","display_name":"Renewable Energy, Sustainability and the Environment"},"field":{"id":"https://openalex.org/fields/21","display_name":"Energy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/photosystem-ii","display_name":"photosystem II","score":0.9779999852180481},{"id":"https://openalex.org/keywords/d2-protein","display_name":"D2 protein","score":0.9369999766349792},{"id":"https://openalex.org/keywords/histidine-residues","display_name":"histidine residues","score":0.949999988079071},{"id":"https://openalex.org/keywords/synechocystis-sp-pcc-6803","display_name":"Synechocystis sp. PCC 6803","score":0.9150000214576721},{"id":"https://openalex.org/keywords/site-directed-mutagenesis","display_name":"site-directed mutagenesis","score":0.796999990940094},{"id":"https://openalex.org/keywords/cp43","display_name":"CP43","score":0.7080000042915344},{"id":"https://openalex.org/keywords/cp47","display_name":"CP47","score":0.9959999918937683},{"id":"https://openalex.org/keywords/herbicide-binding","display_name":"herbicide binding","score":0.8379999995231628},{"id":"https://openalex.org/keywords/low-temperature-fluorescence","display_name":"low-temperature fluorescence","score":0.7829999923706055},{"id":"https://openalex.org/keywords/protein-destabilization","display_name":"protein destabilization","score":0.7889999747276306},{"id":"https://openalex.org/keywords/cyanobacteria","display_name":"cyanobacteria","score":0.8169999718666077}],"concepts":[{"id":"https://openalex.org/C80298142","wikidata":"https://www.wikidata.org/wiki/Q22327014","display_name":"Photosystem II","level":3,"score":0.8218531608581543},{"id":"https://openalex.org/C2780238584","wikidata":"https://www.wikidata.org/wiki/Q7662346","display_name":"Synechocystis","level":4,"score":0.7870924472808838},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.704985499382019},{"id":"https://openalex.org/C2778460671","wikidata":"https://www.wikidata.org/wiki/Q485277","display_name":"Histidine","level":3,"score":0.700129508972168},{"id":"https://openalex.org/C177499756","wikidata":"https://www.wikidata.org/wiki/Q7117940","display_name":"P680","level":5,"score":0.6920738220214844},{"id":"https://openalex.org/C2775895851","wikidata":"https://www.wikidata.org/wiki/Q185906","display_name":"Asparagine","level":3,"score":0.657031238079071},{"id":"https://openalex.org/C188231169","wikidata":"https://www.wikidata.org/wiki/Q418676","display_name":"Photosynthetic reaction centre","level":3,"score":0.5564447641372681},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5146232843399048},{"id":"https://openalex.org/C104292427","wikidata":"https://www.wikidata.org/wiki/Q899781","display_name":"Protein subunit","level":3,"score":0.5019233226776123},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4968293011188507},{"id":"https://openalex.org/C2776165026","wikidata":"https://www.wikidata.org/wiki/Q188017","display_name":"Tyrosine","level":2,"score":0.4551146626472473},{"id":"https://openalex.org/C154828652","wikidata":"https://www.wikidata.org/wiki/Q4339518","display_name":"Photosystem I","level":4,"score":0.4175458550453186},{"id":"https://openalex.org/C2776373379","wikidata":"https://www.wikidata.org/wiki/Q43177","display_name":"Chlorophyll","level":2,"score":0.41277840733528137},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3572632968425751},{"id":"https://openalex.org/C183688256","wikidata":"https://www.wikidata.org/wiki/Q11982","display_name":"Photosynthesis","level":2,"score":0.3490634560585022},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.32127365469932556},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.2322465479373932},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10859787464141846},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1515/znc-1987-0620","doi":"https://doi.org/10.1515/znc-1987-0620","is_oa":true,"landing_page_url":"https://doi.org/10.1515/znc-1987-0620","pdf_url":"https://www.degruyter.com/document/doi/10.1515/znc-1987-0620/pdf","source":{"id":"https://openalex.org/S67401564","display_name":"Zeitschrift f\u00fcr Naturforschung C","issn_l":"0341-0471","issn":["0341-0471","0939-5075","1865-7125"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift f\u00fcr Naturforschung C","raw_type":"journal-article"},{"id":"doi:10.1515/znc-1987-7-803","doi":"https://doi.org/10.1515/znc-1987-7-803","is_oa":true,"landing_page_url":"https://doi.org/10.1515/znc-1987-7-803","pdf_url":"https://www.degruyter.com/document/doi/10.1515/znc-1987-7-803/pdf","source":{"id":"https://openalex.org/S67401564","display_name":"Zeitschrift f\u00fcr Naturforschung C","issn_l":"0341-0471","issn":["0341-0471","0939-5075","1865-7125"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift f\u00fcr Naturforschung C","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1515/znc-1987-0620","doi":"https://doi.org/10.1515/znc-1987-0620","is_oa":true,"landing_page_url":"https://doi.org/10.1515/znc-1987-0620","pdf_url":"https://www.degruyter.com/document/doi/10.1515/znc-1987-0620/pdf","source":{"id":"https://openalex.org/S67401564","display_name":"Zeitschrift f\u00fcr Naturforschung C","issn_l":"0341-0471","issn":["0341-0471","0939-5075","1865-7125"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310313990","host_organization_name":"De Gruyter","host_organization_lineage":["https://openalex.org/P4310313990"],"host_organization_lineage_names":["De Gruyter"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zeitschrift f\u00fcr Naturforschung C","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2186470745.pdf","grobid_xml":"https://content.openalex.org/works/W2186470745.grobid-xml"},"referenced_works_count":1,"referenced_works":["https://openalex.org/W2490682949"],"related_works":["https://openalex.org/W76658436","https://openalex.org/W2154943115","https://openalex.org/W1995707055","https://openalex.org/W2203651561","https://openalex.org/W2095548295","https://openalex.org/W2132719679","https://openalex.org/W2189409596","https://openalex.org/W1964474487","https://openalex.org/W2134000559","https://openalex.org/W2214008628"],"abstract_inverted_index":{"Site-directed":[0],"mutations":[1],"were":[2],"created":[3],"in":[4,33,62,107,123,160,194],"the":[5,15,26,118,124,132,135,139,143,179,195],"cyanobacterium":[6],"Synecliocystis":[7],"6803":[8],"to":[9,52,130,154,185],"alter":[10],"specific":[11],"histidine":[12],"residues":[13,122],"of":[14,97,117,147,162,174,192],"photosystem":[16],"II":[17,59,67,181],"(PS":[18],"II)":[19],"D2":[20,125,136,177],"protein.":[21],"In":[22,172],"one":[23],"mutant":[24,35,44,80],"(tyr-197).":[25],"his-197":[27,119,157],"residue":[28],"was":[29,38,70,73,104],"replaced":[30],"by":[31,190],"tyrosine,":[32],"another":[34],"(asn-214).":[36],"his-214":[37,121,165],"changed":[39],"into":[40],"asparagine.":[41],"The":[42,78],"tyr-197":[43],"did":[45,91],"not":[46,92],"show":[47],"any":[48],"low-temperature":[49,84],"fluorescence":[50,85],"attributable":[51],"PS":[53,58,66,74,180],"II.":[54],"but":[55,90],"contained":[56],"a":[57,82,94,113,175],"chlorophyll-protein.":[60,68],"CP-47,":[61],"significant":[63,95],"quantities.":[64],"Another":[65],"CP-43,":[69],"absent,":[71],"as":[72,188],"II-related":[75],"herbicide":[76],"binding.":[77],"asn-214":[79],"showed":[81],"blue-shifted":[83],"maximum":[86],"around":[87],"682":[88],"nm.":[89],"have":[93,150],"amount":[96],"membrane-incorporated":[98],"CP-43":[99],"or":[100],"CP-47.":[101],"Herbicide":[102],"binding":[103,161],"also":[105],"absent":[106],"this":[108,155],"mutant.":[109],"These":[110],"data":[111],"indicate":[112],"very":[114],"important":[115],"role":[116],"and":[120,127,138,164,170],"protein,":[126,178],"are":[128],"interpreted":[129],"support":[131],"hypothesis":[133],"that":[134],"protein":[137],"M":[140],"subunit":[141],"from":[142],"photosynthetic":[144],"reaction":[145],"center":[146],"purple":[148],"bacteria":[149],"analogous":[151],"functions.":[152],"According":[153],"hypothesis,":[156],"is":[158],"involved":[159],"P680,":[163],"forms":[166],"ligands":[167],"with":[168],"Q\u1d00":[169],"Fe2+.":[171],"absence":[173],"functional":[176],"core":[182],"complex":[183],"appears":[184],"be":[186],"destabilized":[187],"evidenced":[189],"loss":[191],"chlorophvll-proteins":[193],"mutants.":[196]},"counts_by_year":[{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}