{"id":"https://openalex.org/W2186469841","doi":"https://doi.org/10.1152/ajpheart.1987.253.1.h31","title":"Relation between oxygen consumption and pressure-volume area of in situ dog heart","display_name":"Relation between oxygen consumption and pressure-volume area of in situ dog heart","publication_year":1987,"publication_date":"1987-07-01","ids":{"openalex":"https://openalex.org/W2186469841","doi":"https://doi.org/10.1152/ajpheart.1987.253.1.h31","mag":"2186469841","pmid":"https://pubmed.ncbi.nlm.nih.gov/3605369"},"language":"en","primary_location":{"id":"doi:10.1152/ajpheart.1987.253.1.h31","doi":"https://doi.org/10.1152/ajpheart.1987.253.1.h31","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpheart.1987.253.1.h31","pdf_url":null,"source":{"id":"https://openalex.org/S87338489","display_name":"American Journal of Physiology-Heart and Circulatory Physiology","issn_l":"0363-6135","issn":["0363-6135","1522-1539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Heart and Circulatory Physiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076504113","display_name":"Takashi Nozawa","orcid":"https://orcid.org/0000-0002-1822-5553","observed_orcids":["https://orcid.org/0000-0002-1822-5553","https://orcid.org/0009-0007-7655-7242"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"T. Nozawa","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112222861","display_name":"Yoshio Yasumura","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y. Yasumura","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081419924","display_name":"Shiho Futaki","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. Futaki","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005886945","display_name":"Nobuaki Tanaka","orcid":"https://orcid.org/0000-0002-8324-1728","observed_orcids":["https://orcid.org/0000-0002-8324-1728"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N. Tanaka","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Y. Igarashi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y. Igarashi","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111712544","display_name":"Yasutoshi Goto","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y. Goto","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054598335","display_name":"Hiroyuki Suga","orcid":"https://orcid.org/0000-0001-8977-4691","observed_orcids":["https://orcid.org/0000-0001-8977-4691"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H. Suga","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.9824,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.93959003,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"253","issue":"1","first_page":"H31","last_page":"H40"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.9657999873161316,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.9657999873161316,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.014100000262260437,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11700","display_name":"Hemodynamic Monitoring and Therapy","score":0.0044999998062849045,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oxygen-consumption","display_name":"oxygen consumption","score":0.9670000076293945},{"id":"https://openalex.org/keywords/pressure-volume-area","display_name":"pressure-volume area","score":0.9179999828338623},{"id":"https://openalex.org/keywords/end-systolic-pressure-volume-relationship","display_name":"end-systolic pressure-volume relationship","score":0.8579999804496765},{"id":"https://openalex.org/keywords/left-ventricular-contractility","display_name":"left ventricular contractility","score":0.9369999766349792},{"id":"https://openalex.org/keywords/dobutamine","display_name":"dobutamine","score":0.8360000252723694},{"id":"https://openalex.org/keywords/aortic-occlusion","display_name":"aortic occlusion","score":0.8730000257492065},{"id":"https://openalex.org/keywords/myocardial-work","display_name":"myocardial work","score":0.4449999928474426}],"concepts":[{"id":"https://openalex.org/C2781185063","wikidata":"https://www.wikidata.org/wiki/Q422782","display_name":"Dobutamine","level":3,"score":0.9229066371917725},{"id":"https://openalex.org/C2778921608","wikidata":"https://www.wikidata.org/wiki/Q2002035","display_name":"Ventricle","level":2,"score":0.7986000180244446},{"id":"https://openalex.org/C39133596","wikidata":"https://www.wikidata.org/wiki/Q5165683","display_name":"Contractility","level":2,"score":0.5987386703491211},{"id":"https://openalex.org/C83974742","wikidata":"https://www.wikidata.org/wiki/Q179405","display_name":"Reflex","level":2,"score":0.5456616878509521},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5094037652015686},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.49950575828552246},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.4505794048309326},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.44420239329338074},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.3886590600013733},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.37419354915618896},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3389691412448883},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.2239786982536316}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001794","descriptor_name":"Blood Pressure","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D001810","descriptor_name":"Blood Volume","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D004280","descriptor_name":"Dobutamine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004285","descriptor_name":"Dogs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D009206","descriptor_name":"Myocardium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010101","descriptor_name":"Oxygen Consumption","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1152/ajpheart.1987.253.1.h31","doi":"https://doi.org/10.1152/ajpheart.1987.253.1.h31","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpheart.1987.253.1.h31","pdf_url":null,"source":{"id":"https://openalex.org/S87338489","display_name":"American Journal of Physiology-Heart and Circulatory Physiology","issn_l":"0363-6135","issn":["0363-6135","1522-1539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320261","host_organization_name":"American Physical Society","host_organization_lineage":["https://openalex.org/P4310320261"],"host_organization_lineage_names":["American Physical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Heart and Circulatory Physiology","raw_type":"journal-article"},{"id":"pmid:3605369","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3605369","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of physiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2049023692","https://openalex.org/W983654459","https://openalex.org/W66529803","https://openalex.org/W2432280332","https://openalex.org/W2113480513","https://openalex.org/W2318058409","https://openalex.org/W2099617921","https://openalex.org/W2078013759","https://openalex.org/W2048888717","https://openalex.org/W2415804143"],"abstract_inverted_index":{"We":[0,144],"studied":[1],"the":[2,9,15,23,27,38,71,76,82,88,109,114,139,152],"relation":[3],"between":[4],"O2":[5],"consumption":[6],"(VO2)":[7],"and":[8,22,61,70,107,123,148,166],"systolic":[10],"pressure-volume":[11,29],"area":[12],"(PVA)":[13],"in":[14,46,81,83,87,93,159,163,168,170],"left":[16],"ventricle":[17],"of":[18,26,37,75,98],"open-chest":[19],"dogs.":[20],"PVA":[21,45,147],"slope":[24,130],"(Emax)":[25],"end-systolic":[28],"line":[30,78,111],"were":[31,79],"determined":[32],"by":[33,101,105,118,124,151],"an":[34,169],"abrupt":[35],"occlusion":[36],"ascending":[39],"aorta.":[40],"VO2":[41,72,115,160],"linearly":[42],"correlated":[43],"with":[44,58,66,120,126,136,161],"control":[47],"contractile":[48,99],"state,":[49],"where":[50],"Emax":[51,69,104,149],"was":[52,141],"15.8":[53],"+/-":[54,63],"4.4":[55],"(SD)":[56],"mmHg/ml":[57,65],"intact":[59,121],"reflexes":[60,122],"11.5":[62],"1.2":[64],"blocked":[67,127],"reflexes.":[68,128],"axis":[73,116],"intercept":[74,117],"VO2-PVA":[77,110],"greater":[80],"situ":[84,171],"heart":[85,92],"than":[86],"excised":[89],"cross-circulated":[90],"dog":[91,172],"our":[94],"previous":[95],"study.":[96],"Enhancement":[97],"state":[100],"dobutamine":[102],"increased":[103],"60-80%":[106],"shifted":[108],"upward,":[112],"increasing":[113],"38%":[119],"79%":[125],"The":[129],"had":[131],"a":[132],"tendency":[133],"to":[134],"increase":[135,140],"dobutamine,":[137],"but":[138],"statistically":[142],"insignificant.":[143],"conclude":[145],"that":[146],"obtained":[150],"aortic-occlusion":[153],"method":[154],"can":[155],"account":[156],"for":[157],"changes":[158,162],"loading":[164],"conditions":[165],"contractility":[167],"heart.":[173]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}